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http://uwcrispr.org

Service facility offering generation of novel transgenic mouse models using CRISPR/Cas9 gene editing technology. Standard service includes consultation, design, testing, prep, mouse embryo microinjection, and genotyping.

Proper citation: University of Washington Mouse CRISPR Core Facility (RRID:SCR_025836) Copy   

•   Source: SciCrunch Registry

https://www.brandeis.edu/science/resources/light-microscopy/index.html

Facility houses 13 high-end light microscopes including point scanning and spinning disk confocals, Airyscan, 3D-STED super resolution, widefield and TIRF systems. Core offers training, consultation and access to powerful analysis computers with licensed softwares.

Proper citation: Brandeis University Light Microscopy Core Facility (RRID:SCR_025892) Copy   

•   Source: SciCrunch Registry

http://www.kumc.edu/mspc

Mass spectrometry based proteomics.

Proper citation: University of Kansas Medical Center Mass Spectrometry and Proteomics Core Facility (RRID:SCR_025893) Copy   

•   Source: SciCrunch Registry

https://www.rockefeller.edu/hpc/

Provide Rockefeller University researchers and collaborators with infrastructure necessary for computationally intensive workloads, as well as training and support for using these resources.

Proper citation: Rockefeller University High Performance Computing Core Facility (RRID:SCR_025889) Copy   

•   Source: SciCrunch Registry

https://douglas.research.mcgill.ca/molecular-and-cellular-microscopy-platform-mcmp/

Provides access to various microscopes and services, support and training for fluorescence microscopy experiments and image analysis. Facility offers imaging tasks from basic neuron reconstruction to high-speed, deep-tissue optogenetic experiments in brain slices or live animals.

Proper citation: Douglas Institute Molecular and Cellular Microscopy Platform Core Facility (RRID:SCR_026037) Copy   

•   Source: SciCrunch Registry

http://www.douglasbrainbank.ca

Based at the Douglas Research Centre, the Douglas Brain Bank (DBB) houses a large collection of brains from people with diverse psychiatric disorders, including schizophrenia, major depression, bipolar disorder and substance use disorders, as well as brains from individuals with various neurological and developmental disorders such as amyotrophic lateral sclerosis (ALS), Alzheimers disease and autism spectrum disorder (ASD). In addition, the DBCBB manages a large relational database containing demographic, clinical and developmental histories from donors.

Proper citation: Douglas Mental Health University Institute Douglas Brain Bank Core Facility (RRID:SCR_025991) Copy   

•   Source: SciCrunch Registry

https://versiti.org/versiti-blood-research-institute/core-facilities-services/bioinformatics

Core offers bioinformatics consultation, training, and data analysis to help investigators analyze and understand large-scale biological datasets required from different platforms, including next generation sequencing, array-based technologies and mass spectrometry. Provides development and operation of standard and advanced data processing pipelines, covering tasks such as bulk next-generation sequencing analysis (e.g., RNA-Seq, DNA-Seq, methyl-Seq, and ChIP-Seq), single-cell analysis, transcriptome and genome annotation, variant detection and interpretation and metagenomics. Our team members have extensive experience in bioinformatics, biostatistics, genomics, genetics, transcriptomics and translational informatics in human, animal and microbial systems. Our expertise includes big data analysis, statistical analysis, machine learning, neuro network, software development and high-performance computing. Our approach prioritizes scientific collaboration, going beyond mere service provision to leverage our skills and knowledge for the success of your projects. Offers support for grant applications, including key personnel involvement, support letters, and analytical method write-ups.

Proper citation: Versiti Blood Research Institute Bioinformatics Core Facility (RRID:SCR_025993) Copy   

•   Source: SciCrunch Registry

https://bioinspired.syr.edu/MRC/

Provides services involved in fundamental studies of biochemical and physical processes controlling cell functions to development of new technologies for biomedical applications.

Proper citation: Syracuse University BioInspired Materials Research Core Facility (RRID:SCR_025987) Copy   

•   Source: SciCrunch Registry

http://www.lsuhs.edu/fwcc-biorepository

Provides IRB-approved research projects or clinical trials with human tissue samples or hematological samples. Supports translational research by functioning as primary fresh-frozen tissue acquisition and processing facility for human solid tissue and hematopoietic specimens.FWCC Biorepository works in collaboration with medical and surgical teams at Ochsner LSU Health Shreveport, the Department of Pathology to procure remnant tissue for research purposes, and investigators in need of biospecimens for their research. Provides customized services and equipment to assist investigators in the procurement, analyses, and clinicopathologic correlation of human tissue specimens.

Proper citation: Louisiana State University Health Sciences Center Shreveport Feist Weiller Cancer Center Biorepository Core Facility (RRID:SCR_026020) Copy   

•   Source: SciCrunch Registry

https://dac.institutducerveau-icm.org/

Core provides structural support and expertise in processing, integrating, analyzing and managing neuroscience data.

Proper citation: Paris Brain Institute Data Analysis Core Facility (RRID:SCR_026138) Copy   

•   Source: SciCrunch Registry

https://ecosystemslab.sites.stanford.edu/

Ecosystems Laboratory provides bench space, laboratory supplies, chemicals, sample preparation equipment, and sample storage space to enhance and facilitate research within Stanford University community.

Proper citation: Stanford Ecosystems Shared Laboratory Core Facility (RRID:SCR_026190) Copy   

•   Source: SciCrunch Registry

https://research.yale.edu/cores/keck-mass-spectrometry-proteomics-resource

Core provides proteomics and small molecule mass spectrometry services to separate, characterize, profile, and quantify analytes from complex biological samples.

Proper citation: Yale Keck Mass Spectrometry and Proteomics Resource Core Facility (RRID:SCR_026192) Copy   

•   Source: SciCrunch Registry

https://www.bcm.edu/research/atc-core-labs/metabolomics-core

Core provides Untargeted Metabolomics, Untargeted Lipidomics, Targeted Metabolomics, Metabolomics Flux and analysis services.

Proper citation: Baylor College of Medicine Metabolomics Core Facility (RRID:SCR_026214) Copy   

•   Source: SciCrunch Registry

https://www.utmb.edu/mgf/next-generation-sequencing-core

Core offers Next Generation Sequencing services using Element Biosciences AVITI short read sequencer, PacBio Revio and Oxford Nanopore Promethion/GridIon long read sequencers along with 10X Genomics X, 10X Genomics Visium CytAssist, and 10X Xenium Analyzer single cell/spatial technologies.

Proper citation: University of Texas Medical Branch at Galveston Next Generation Sequencing Core Facility (RRID:SCR_026169) Copy   

•   Source: SciCrunch Registry

https://www.mdanderson.org/research/research-resources/core-facilities/cytogenetics-and-cell-authentication-core.html

Facility offers conventional as well as molecular cytogenetic services including karyotyping, analysis of genomic instability, fluorescence in situ hybridization, telomere analysis, Spectral Karyotyping, species identification, inter-species and intra-species cell line contamination, STR fingerprinting service for cell line authentication, mycoplasma contamination testing and distribution of cell lines.

Proper citation: University of Texas MD Anderson Cytogenetics and Cell Authentication Core Facility (RRID:SCR_026262) Copy   

•   Source: SciCrunch Registry

https://www.uni.lu/lcsb-en/facilities/scientific-platforms/bioimaging-platform/

Bioimaging Platform provides access to and support for wide variety of advanced microscopy and flow cytometry instruments, enabling researchers to perform studies from the tissue level and down to sub-cellular scales. Provides access to analytical imaging technologies. As such, the platform comprises of advanced microscopy systems for high resolution studies of fixed and live samples as well as for low-phototoxicity imaging of whole organs and organisms.Bioimaging platform includes seven advanced microscopy systems, two flow cytometers and several high-performance analysis workstations.

Proper citation: University of Luxembourg LCSB Bioimaging Platform Core Facility (RRID:SCR_026352) Copy   

•   Source: SciCrunch Registry

https://benaroyaresearch.org/our-research/core-labs/human-immunophenotyping-core

Core provides access to technologies and services enabling study of human immune-mediated diseases. Offers expertise in human immunology along with innovative assays and technology. Core specializes in high-parameter single-cell assays utilizing conventional, spectral, and mass cytometry (CyTOF), which can be paired with genomic and bioninformatic analyses through our connections with other outstanding BRI cores. Other services include cell sorting, short-term in vitro assays, DNA/RNA extraction, qPCR, and ELISA or multiplex protein analysis (Luminex), guidance on study design and training on new technologies, execution, data analysis and interpretation.

Proper citation: Benaroya Research Institute Human Immunophenotyping Core Facility (RRID:SCR_026355) Copy   

•   Source: SciCrunch Registry

https://sites.google.com/fieldmuseum.org/research/laboratories/core-laboratories/dna?authuser=0

Interdepartmental, multiuser core facility dedicated to genetic analysis and preservation of the world's biodiversity. Provides equipment used in molecular biology enabling to pursue study of genetic diversity throughout tree of life and at all taxonomic levels, from populations to classes to phyla of organisms.

Proper citation: Field Museum of Natural History Pritzker Laboratory for Molecular Systematics and Evolution Core Facility (RRID:SCR_026354) Copy   

•   Source: SciCrunch Registry

https://www.research.uky.edu/flow-cytometry-and-immune-monitoring-core-facility

Core supports research requiring flow cytometry techniques in basic and translational research. Provides access to equipment, and technical and scientific expertise for comprehensive analysis of immune responses. Uses standardized and optimized SOPs and study protocols to obtain reproducible and quality results for our collaborating investigators in cost-effective manner.

Proper citation: University of Kentucky Flow Cytometry and Immune Monitoring Core Facility (RRID:SCR_026358) Copy   

•   Source: SciCrunch Registry

https://www.montana.edu/animalresources/

AAALAC approved animal research facility to study diverse number of animal species. Core maintains animal housing rooms, observation rooms, and procedure rooms at BSL 1 and 2 containment levels. The ARC is supported by certified veterinarians and animal care technicians who provide technical support and veterinary care.

Proper citation: Montana State University Animal Resources Center Core Facility (RRID:SCR_026351) Copy   

•   Source: SciCrunch Registry