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https://www.joslin.org/islet-isolation-core.html

Core facility that provides the following services: Rodent and Porcine Islet Isolation Services, Training Services. The main objective of the Islet Isolation Core is to provide Islets of Langerhans to investigators in the Boston area and beyond. By receiving islets from the Core one is assured of consistent high quality and purity of islets for experiments. The Core can isolate rodent and neonatal porcine islets. This leaves the investigator to concentrate on experiments rather than the complexity of islet isolation. The Core can buy the animals or the investigator can provide their own, such as special transgenic mice. Over the last five years the Core has isolated more than 10 million islets. They also provide training and advice. The Core can provide training not only for the isolation procedure but islet viability, islet size measurement, GSIS (Glucose Stimulated Insulin Secretion), STZ-induced diabetes, transplantation under the kidney capsule, and islet graft retrieval.

Proper citation: Joslin Diabetes Center Islet Isolation Core (RRID:SCR_012299) Copy   

•   Source: SciCrunch Registry

http://www.schepens.harvard.edu/graphics

Core facility that provides the following services: Web and graphic services, Web design and content management service, Photography service. Peter Mallen is a designer and illustrator who manages a full-service web and graphics studio in a moderately sized scientific research facility, Schepens Eye Research Institute. He provides a full range of graphic design, scientific illustration, web design and development, content management, and general design and production services. His products are utilized by: faculty and scientific staff (books, scientific publications, slide shows, grant applications); professional staff (Administration, Development & Public Affairs; brochures, books, pamphlets); the general public (Institute websites) as well as clients of our 250-seat state-of-the-art conference center, Starr Center for Scientific Communications.

Proper citation: Harvard SERI Graphic Services Core (RRID:SCR_012309) Copy   

•   Source: SciCrunch Registry

http://www.massgeneral.org/psychiatry/research/pngu_home.aspx

Core facility that provides the following services: SNP genotyping, qPCR for CNV detection / confirmation, Genetic analysis services, DNA extraction, quantification, sample preparation, tracking, and storage. This resource provides custom genotyping (SNP, other), qPCR for CNV detection/confirmation, DNA extraction, quantification, sample preparation, tracking, and storage, and related services to further the PNGU mission of identifying and characterizing the genetic basis of psychiatric, behavioral, and neurodevelopmental disorders and to translate these discoveries to improvements in clinical care and public health.

Proper citation: MGH Psychiatric and Neurodevelopmental Genetics Unit Core Lab (RRID:SCR_012301) Copy   

•   Source: SciCrunch Registry

http://www.neurodiscovery.harvard.edu/resources/atrc.html

Core facility that provides provides state-of-the-art molecular pathology resources to the Harvard community including laser capture microscopy, DNA/RNA/miRNA quality/expression analysis, Luminex FlexMap 3D multiplex bead cytometry, and real-time PCR. The ATRC is a fee-for-use facility. For NeuroDiscovery members, the first 10 hours of training, consultation and instrument use is free. This initial period is intended to provide a first time user with preliminary data/proof of concept regarding their project, and is generally sufficient when investigators work under the aegis of ATRC staff. Thereafter, the base fee varies depending on activity and the extent of your proposed work. Project-based charge-back agreements for large projects can be negotiated with the ATRC Director, Dr. Charles Vanderburg. Although priority is given to NeuroDiscovery members investigating neurodegenerative diseases and the CNS, the facility is also available to any academic investigators within the Harvard medical community and the greater-Boston research community. Under special arrangements the facility may also be made available to the commercial sector. Please contact ATRC Director, Dr. Charles Vanderburg, for details.

Proper citation: HNDC Advanced Tissue Resource Center (RRID:SCR_012670) Copy   

•   Source: SciCrunch Registry

http://bioinformatics.hms.harvard.edu/

Core facility that offers consultations on basic questions in research computing, bioinformatics and computational biology during the initial stages of study design and grant proposals as well as for ongoing, funded studies requiring external expertise. Core has experience in large-scale data management, database design and software development. Staff members can provide assistance in quality assurance and analysis of gene expression arrays, genome-wide SNP arrays, CNV studies and different aspects of second-generation sequencing technologies such as ChIP-seq, RNA-Seq or resequencing efforts. Services also include provision of external information generated from public database, data curation and assistance on choosing the right data format and annotation standard to ensure best practices in data management and submission are being maintained.

Proper citation: Harvard Chan Bioinformatics Core (RRID:SCR_012655) Copy   

•   Source: SciCrunch Registry

http://flowcytometry.sysbio.med.harvard.edu/

Core facility that provides the following services: Sorting and analysis services. The facility houses two state-of-the-art BD analyzers with high-throughput capability, a Stratedigm benchtop analyzer, a high-speed BD cell sorter, and both Mac and PC workstations for data analysis. Sorting services are offered through the facility, as well as instrument and software training.

Proper citation: HMS Systems Biology Flow Cytometry Facility (RRID:SCR_012696) Copy   

•   Source: SciCrunch Registry

http://famu.eagle-i.net/i/00000136-ea13-62c9-2e84-177780000000

A core facility at the Florida Agricultural and Mechanical University.

Proper citation: FAMU Drug Discovery Core Facility (RRID:SCR_000876) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-7441-2a90-c437-ff0b80000000

Core facility that provides the following services: Tissue trimming, cassetting, processing, and embedding, Cutting and staining of paraffin-embedded and cryostat sections, Immunohistochemistry for both routine and novel markers, In situ hybridization, using chromogenic or radioactive detection methods, Laser capture microdissection.

Tissue analysis is critical to validation and evaluation of animal models of human cancer, and human cancer tissues serve as the operating system for translational research. The facility supports a wide spectrum of cancer-relevant research, from basic studies on pathogenic mechanisms in cancer to translational research focused on the development of new tests for biomarkers that stratify patients and direct therapy. The Specialized Histopathology (SHP) Core, was created in 2005 by consolidating five histopathology cores into a single unit with two performance sites: Longwood, Directed by Jon Aster and based at the Brigham and Women?s Hospital and MGH, Directed by Anat Stemmer-Rachamimov and based at Massachusetts General Hospital East in Charlestown. The SHP Core provides professional and technical research pathology services to DF/HCC investigators working in diverse organisms (e.g., rodents, fish, and monkeys) or human tissues. The Core also assists in experimental design and the development and interpretation of tests and their results. As of July 2012, the Longwood site offers CLIA Certified services.

Proper citation: DF/HCC Specialized Histopathology Services Core (RRID:SCR_000872) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-c7e5-e09d-a061-4a6580000000

Core facility that provides the following services: Flow cytometry assay service, Data management system.

The BD FACSCalibur system combines unique dual-laser technology, an automated sample loader option, and powerful software to provide the high throughput necessary to meet productivity requirements of clinical laboratories. The modularity and innovative technology designed into the BD FACSCalibur system also offers investigators the performance and flexibility required for a variety of research applications. Please note that since the NERCE program will end in February 2014, our ability to support new requests for services is limited.

Proper citation: HMS NERCE FACSCalibur Flow Cytometer Resource (RRID:SCR_000879) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013c-40b7-7a2a-f162-a2b280000000

Core facility that provides the following services: PET/SPECT/CT image analysis.

Proper citation: Penn Small Animal Imaging Facility: PET/SPECT/CT Sub-Core (RRID:SCR_000890) Copy   

•   Source: SciCrunch Registry

http://biology.hunter.cuny.edu/index.php?option=com_content&view=article&id=138&Itemid=117

Facility which provides instruments and instrument resources for analyzing DNA, RNA, protein, and radio-labeled substances.

Proper citation: Hunter Genomic Facility (RRID:SCR_001983) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012e-3517-ac53-550e-f59280000000

Core facility that provides metals analytical capabilities to biomedical and non-biomedical researchers and serves as a source for study design consultation and sample QA/QC requirements. The transport, fate, exposure, and toxic effects of heavy metals is a primary focus of research at the Center. It operates as a modified fee-for-service laboratory. Researchers have the option of having the samples run by the Service staff, or of receiving instruction (for themselves or a doctoral or post doctoral trainee) on how to operate the analytical equipment and analyze their own samples. Both options have associated fees and, as with other services, facility access funds can be requested internal or external services when individual grant support is not yet available.

Proper citation: HSPH Trace Metals Laboratory (RRID:SCR_002819) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/00000137-e19e-59a0-d807-77a880000000

Microscopists at Weld Hill will find a range of tools from the simple hand lens to the confocal microscope for 3-D reconstructions.

Proper citation: Arnold Arboretum of Harvard University: Weld Hill Microscopy Lab (RRID:SCR_004485) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-c61a-a13e-b341-4bb480000000

Core facility that provides the following services: Energy Expenditure Assessment, Body Composition Assessment, Physical Activity Assessment. This component of the core utilizes existing institutional resources for measurement of energy balance and provides personnel support that permit assessment of research in energy balance and nutrition assessment.

Proper citation: Vanderbilt Energy Balance Core Laboratory (RRID:SCR_006665) Copy   

•   Source: SciCrunch Registry

http://dartmouth.eagle-i.net/i/0000012a-24fd-6cc0-d8a1-249280000000

Core facility that provides the following services: 7500 fast Q-PCR service, MALDI MS service, Agilent 2100 bioanalyzer service, NanoDrop 1000 service.

Proper citation: Dartmouth Shared Instruments Core Laboratory (RRID:SCR_006415) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012c-60c2-395c-c437-ff0b80000000

Core facility that provides the following services: Cell immortalization through retroviral or lentiviral vectors service, Microscopy training, User-based microscopy service.

Proper citation: BWH Cell Culture and Microscopy Core (RRID:SCR_005562) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000012d-56f2-62b7-2162-17a280000000

Core facility that provides the following services: Ultrasound/sonography access service. Ultrasound, which is also known as sonography, is a painless, non-invasive imaging technique that lets us look inside your child''s body without the use of radiation. It uses high-frequency sound waves to create pictures of organs, bones, tissues and blood vessels.

Proper citation: CHB Ultrasound (RRID:SCR_009608) Copy   

•   Source: SciCrunch Registry

http://harvard.eagle-i.net/i/0000013c-fd63-dfbb-ea7a-a3a980000000

Core facility that provides the following services: Circulating Tumor Cell analysis, Circulating Tumor Cell Purification. The Circulating Tumor Cell Core Facility uses immunomagnetic technology developed by Veridex, LLC (Raritan, NJ) to isolate rare tumor cells from whole blood. Isolated tumor cells can then be counted or used for downstream analysis such as molecular studies or flow cytometry.

Proper citation: BWH Circulating Tumor Cell Core (RRID:SCR_008258) Copy   

•   Source: SciCrunch Registry

http://cdrewu.eagle-i.net/i/00000136-0961-ccb9-1a88-e81c80000000

Core facility that provides the following services: Establishing primary cell line from human tissues, HLA genotyping, Immunohistochemical staining, Immortalization of primary cell lines, Testing RNA quality for mRNA array analysis. Molecular and Translational research in oncology

Proper citation: CDU Cancer Research and Training Core Facility (RRID:SCR_009580) Copy   

•   Source: SciCrunch Registry

http://cau.eagle-i.net/i/00000136-59de-ff9a-982a-4eef80000000

The mission of the CCRTD Research Support Core Facilities is to provide the scientists of CCRTD, Clark Atlanta University, and Atlanta University Center with access to modern technology, resources, and instruments essential for cutting-edge research in molecular biology, genomics, proteomics, cell biology, and biological imaging.

Proper citation: CAU CCRTD-Histology Core (RRID:SCR_009412) Copy   

•   Source: SciCrunch Registry