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https://www.utsouthwestern.edu/research/core-facilities/histo-pathology/

Core offers research histology and anatomic pathology services and customized pathology services. Facilitates morphologic and histologic assessment of murine transgenic and knockout phenotypes as well as experimental procedure-based models of disease for basic and clinical research. We utilize expertise in gross pathology, routine histology, immunohistochemistry, tissue microarray, spatial transcriptomics, spatial proteomics, laser-capture microdissection, materials science, photomicrography, and image analysis.

Proper citation: University of Texas Southwestern Medical Center Dallas Histo Pathology Core Facility (RRID:SCR_027706) Copy   

•   Source: SciCrunch Registry

https://viceprovost.tufts.edu/flow-cytometry-core

Core offers Flow and Laser Cytometry equipment and services including FACS Analysis and Cell Sorting, to the scientific community.

Proper citation: Tufts University Laser Cytometry Core Facility (RRID:SCR_027709) Copy   

•   Source: SciCrunch Registry

http://tucf-genomics.tufts.edu/

Core provides protein sequencing services including Next-Generation DNA Sequencing, Peptide Synthesis, Protein Sequencing, and Mass Spectrometry. Provides expert technical and analytical support.

Proper citation: Tufts University Genomics Core Facility (RRID:SCR_027708) Copy   

•   Source: SciCrunch Registry

https://www.mdanderson.org/saif

Core provides access to imaging instrumentation and expertise that is necessary to integrate advanced imaging technologies into basic and translational biomedical research. Services include Assistance in experimental design; Developing specialty equipment and innovative procedures for imaging; Preparing animals for studies, inducing and maintaining appropriate anesthesia and immobilization of animals during imaging;Processing and interpreting data for publication or grant preparation.

Proper citation: University of Texas MD Anderson Cancer Center Small Animal Imaging Facility (RRID:SCR_027643) Copy   

•   Source: SciCrunch Registry

https://sites.ifi.unicamp.br/gate/gate-ats/criogenia-e-vacuo/

Core produces and supplies liquid helium and nitrogen to the entire IFGW academic community. Laboratory is equipped with helium liquefier from Linde and nitrogen liquefier from Stirling Cryogenics. In addition, it maintains complex support infrastructure essential for production and distribution of cryogenic liquids.

Proper citation: State University of Campinas Gleb Wataghin Physics Institute Criogenia/IFGW Core Facility (RRID:SCR_027638) Copy   

•   Source: SciCrunch Registry

https://www.crukscotlandinstitute.ac.uk/advanced-technologies/mass-spectrometry.html

Core offers proteomics and metabolomics services. Provides support from experimental design to execution, sample processing, data interpretation, and assistance with presentations, manuscript preparation for publication and deposition of data in public repository and data storage on local server. Provides service analysis of post-translational modifications, such as phosphorylation, ubiquitination, acetylation, and others, with precise site localization on either single protein or for entire proteome.Uses Orbitrap Fusion Lumos coupled to Easy-nLC 1200 HPLC system. Facility instruments are operated with various acquisition methods, including classic Data Dependent Analysis (DDA) or more recent Data Independent Analysis (DIA). Acquired data from different methods are used to accurately identify and measure abundance of proteins and peptides employing different quantitation strategies: Label-free, TMT, pulsed-SILAC and Isotope-labelled Iodoacetamide (for Cysteine oxidation).Provides specialized data analysis software like MaxQuant and Mascot for DDA, Spectronaut for DIA of clinical samples and Perseus and Scaffold for data compilation, analysis, and dissemination.

Proper citation: Cancer Research UK Scotland Institute Mass Spectrometry Core Facility (RRID:SCR_027652) Copy   

•   Source: SciCrunch Registry

https://icahn.mssm.edu/research/resources/deans-cores/cryo

Cryo-Electron Microscopy Core facility at ISM offers EM services with state-of art instruments (Vitrobot for sample preparation, Glacios-2 TEM for imaging biological samples at atomic resolution). We offer single particle analysis (SPA) workflow, imaging drug delivery products (ex: liposomes, LNPs, AAVs..)

Proper citation: Icahn School of Medicine at Mount Sinai Mount Sinai Cryo-EM CoRE Core Facility (RRID:SCR_027649) Copy   

•   Source: SciCrunch Registry

https://chem.vt.edu/analyticalservices/crystallography.html

Core specializes in single-crystal structure determination of small molecules, inorganic materials, and minerals. The facility houses a Rigaku-Oxford Diffraction Synergy Single-Crystal X-ray Diffractometer equipped with both Cu and Mo sources, variable temperature capabilities (90 – 500 K) and the setup to perform high-pressure diamond-anvil studies.

Proper citation: Virginia Tech Crystallography Lab Core Facility (RRID:SCR_027620) Copy   

•   Source: SciCrunch Registry

https://chem.vt.edu/analyticalservices/chromatograhy.html

Facility enables complete qualitative and quantitative analysis of components within complex sample matrices. Provides services for separating mixtures, and supports critical research across numerous fields, including:Chemistry and Biochemistry, Biology and Medicine, Environmental Science and Toxicology, Food, Nutrition, and Pharmaceutical Development. Provides extraction, separation, detection, and quantification of organic and other complex mixtures from gas, solid, or liquid matrices.

Proper citation: Virginia Tech Department of Chemistry Chromatography Core Facility (RRID:SCR_027622) Copy   

•   Source: SciCrunch Registry

https://ccg.uni-koeln.de/

Represents central facility and does not operate for profit, engaging in academic research collaborations and service provision on collaborative basis. Provides infrastructure for all kinds of sequencing, gene mapping and whole genome association studies in complex diseases as well as the validation of copy number variations.

Proper citation: University of Cologne Center for Genomics (CCG) Core Facility (RRID:SCR_027822) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/biostatistics

Core provides expertise on study design and statistical analysis. Devoted to developing and understanding ways to derive scientific inferences from quantitative data and to developing methods for achieving this aim. The staff are highly trained in this field and experienced in all of the specialized areas of statistical techniques including clinical trials methodology, survival analysis, epidemiologic methods, analysis of genomics data, statistical genetics, methods for diagnostic medicine, health services research, survivorship, evidence-based medicine and psychometric methods.

Proper citation: Memorial Sloan Kettering Cancer Center Biostatistics Core Facility (RRID:SCR_027821) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/bioinformatics

Core provides bioinformatics support services including creating and maintaining repository of bioinformatics pipelines, providing customized data analysis support, assisting computational researchers in their research efforts, and training staff in computational and bioinformatics techniques. Provides bioinformatics software applications and pipelines for experimental assays ranging from standard genomics pipelines like RNAseq and variant detection to the growing demand for single-cell processing workflows and new spatial-based assays in transcriptomics and proteomics. Provides training and consulatation.

Proper citation: Memorial Sloan Kettering Cancer Center Bioinformatics Core Facility (RRID:SCR_027794) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/pathology

Biobank and Pathology Core provides resources for human biospecimen-based research to be used to study causes, detection, prevention, and treatment of cancer.Central facility for the collection, processing, storage, and distribution of fresh, frozen, and FFPE-processed human biospecimens (tissues, blood, bone marrow, urine, and other liquid samples) for research use. Core also serves as national resource, as evidenced by the several hundred samples from multiple tumor types that have been provided to the Cancer Genome Atlas (TCGA) and NCI’s CPTAC proteogenomic consortium. Histology Service within the Core facilitates selection of appropriate specimens for tissue analyses and provides the basic services of cutting, dissecting, and staining of fresh-frozen and formalin-fixed, paraffin-embedded tissues. It includes construction of tissue microarray blocks and laser capture microdissection for isolation of pure cell populations and tumor cell enrichment. The Core’s Immunohistochemistry Service provides immunostaining using optimized antibodies for clinico-pathologic research studies.

Proper citation: Memorial Sloan Kettering Cancer Center Biobank and Pathology Core Facility (RRID:SCR_027796) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/comparative-medicine-pathology-0

Core supports animal model use in cancer research through teams including Research Animal Resource Center (RARC) and Laboratory of Comparative Pathology (LCP). Animals are employed in the development of new methods for diagnosis and treatment of cancer as well as the elucidation of the basic biological mechanisms resulting in neoplasia. CCMP’s professional and paraprofessional staff (152 FTE) serve as a consultative and technical resource for MSK investigators on all matters related to animal research.

Proper citation: Memorial Sloan Kettering Cancer Center- Center of Comparative Medicine and Pathology Core Facility (RRID:SCR_027798) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/biotherapeutics

Core provides collaborative process development support to investigators across the Center engaged in new Biotherapeutics initiatives. Core staff are responsible for converting research-lab processes into GMP-compliant manufacturing processes. This includes establishing Standard Operating Procedures (SOPs) and batch records for cell processing, cell engineering, and vector production. Provides full support for cGMP manufacturing of cell products: handling patient cells in cGMP environment, from purification and transduction to expansion and formulation, for use in phase 1 and phase 2 clinical trials. Manufactures vector stocks, oversees biosafety and releases testing of generated projects for human use. This includes analysis of patient cells and vector stocks, assessing characteristics such as phenotype, potency, purity, and stability. Gene transfer and expression analyses are also performed. Core performs analytical post-infusion monitoring. For each trial, the Core develops a comprehensive set of analytical tests to ensure quality and safety of the manufactured drug products.

Proper citation: Memorial Sloan Kettering Cancer Center Biotherapeutics Core Facility (RRID:SCR_027797) Copy   

•   Source: SciCrunch Registry

https://hpc.lums.edu.pk/

LUMS High-Performance Computing (HPC) facility is specialized computational research core providing high-density processing power and large-scale data storage. It serves as a central hub for faculty and students to execute data-intensive simulations, machine learning workflows, and complex modeling across various scientific disciplines.

Proper citation: Lahore University of Management Sciences Syed Babar Ali School of Science and Engineering High Performance Computing Core Facility (RRID:SCR_027827) Copy   

•   Source: SciCrunch Registry

https://research.bidmc.org/redcap-core

REDCap (Research Electronic Data Capture) is a secure HIPAA compliant web-based data collection application hosted by Research and Academic Computing (ARC), a department of Beth Israel Deaconess Medical Center (BIDMC) which is itself part of Beth Israel Lahey Health (BILH). The function of the REDCap Core is to provide REDCap-related services and support to all BILH users.

Proper citation: Beth Israel Deaconess Medical Center BILH/BIDMC REDCap Core Facility (RRID:SCR_027761) Copy   

•   Source: SciCrunch Registry

https://microscopie.ibis.ulaval.ca/

IBIS Microscopy platform offers sample preparation and acces to TEM, SEM, STED, confocals and other microscopes.

Proper citation: Laval University IBIS Imaging and Microscopy Platform Core Facility (RRID:SCR_027763) Copy   

•   Source: SciCrunch Registry

https://www.digitalpsych.org/mindlamp1.html

Core collects data to capture and consider the real-time lived experiences of patients. Uses open-source digital platform and mobile app for neuropsychiatric research and clinical care, to monitor, support, and improve brain health by collecting real-time data (like location, activity, heart rate via sensors), conducting digital assessments (surveys, cognitive tests), and delivering interventions (meditation, journaling, psychoeducation) to patients and clinicians. It helps study behavioral patterns, track symptoms, and personalize mental health treatment through features organized around Learn, Assess, Manage, and Prevent.

Proper citation: BIDMC Division of Digital Psychiatry LAMP platform Core Facility (RRID:SCR_027767) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/immune-monitoring

Core provides laboratory services and translational research to support immune monitoring during cancer immunotherapy. Robust immune monitoring assays are essential for characterizing the immune status in patients receiving novel immune-modulating therapies, and the insights gained from studying the immune response in treated patients may help transition promising therapies from the clinical trial phase to standard of care.

Proper citation: Memorial Sloan Kettering Cancer Center Immune Monitoring Core Facility (RRID:SCR_027800) Copy   

•   Source: SciCrunch Registry