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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
GeneSigDB
 
Resource Report
Resource Website
10+ mentions
GeneSigDB (RRID:SCR_013275) GeneSigDB analysis service resource, data access protocol, data analysis service, data or information resource, data repository, database, production service resource, service resource, software resource, storage service resource, web service Database of traceable, standardized, annotated gene signatures which have been manually curated from publications that are indexed in PubMed. The Advanced Gene Search will perform a One-tailed Fisher Exact Test (which is equivalent to Hypergeometric Distribution) to test if your gene list is over-represented in any gene signature in GeneSigDB. Gene expression studies typically result in a list of genes (gene signature) which reflect the many biological pathways that are concurrently active. We have created a Gene Signature Data Base (GeneSigDB) of published gene expression signatures or gene sets which we have manually extracted from published literature. GeneSigDB was creating following a thorough search of PubMed using defined set of cancer gene signature search terms. We would be delighted to accept or update your gene signature. Please fill out the form as best you can. We will contact you when we get it and will be happy to work with you to ensure we accurately report your signature. GeneSigDB is capable of providing its functionality through a Java RESTful web service. gene, gene signature, curated gene signature, gene expression, gene expression signature, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Dana-Farber Cancer Institute
has parent organization: Computational Biology and Functional Genomics Laboratory at Harvard
Cancer Genome Research Institute ;
Dana-Farber Cancer Institute ;
Women's Cancers Program ;
Claudia Adams Barr Foundation ;
NLM 1R01 LM010129;
NCI 1U19 CA148065;
NHGRI 1P50 HG004233
PMID:22110038 biotools:genesigdb, nlx_149342 https://bio.tools/genesigdb SCR_013275 Gene Signature Data Base, GeneSigDB - Curated Gene Signatures Database 2026-09-12 12:58:01 24
PIAGE
 
Resource Report
Resource Website
PIAGE (RRID:SCR_013124) software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 24,2023. Software program that performs estimation of power and sample sizes required to detect genetic and environmental main, as well as gene-environment interaction (GxE) effects in indirect matched case-control studies (1:1 matching). When the hypothesis of GxE is tested, power/sample size will be estimated for the detection of GxE, as well as for the detection of genetic and environmental marginal effects. Furthermore, power estimation is implemented for the joint test of genetic marginal and GxE effects (Kraft P et al., 2007). Power and sample size estimations are based on Gauderman''s (2002) asymptotic approach for power and sample size estimations in direct studies of GxE. Hardy-Weinberg equilibrium and independence of genotypes and environmental exposures in the population are assumed. The estimates are based on genotypic codes (G=1 (G=0) for individuals who carry a (non-) risk genotype), which depend on the mode of inheritance (dominant, recessive, or multiplicative). A conditional logistic regression approach is used, which employs a likelihood-ratio test with respect to a biallelic candidate SNP, a binary environmental factor (E=1 (E=0) in (un)exposed individuals), and the interaction between these components. (entry from Genetic Analysis Software) gene, genetic, genomic, r, ms-windows, linux is listed by: Genetic Analysis Software THIS RESOURCE IS NO LONGER IN SERVICE nlx_154534, SCR_009372, nlx_154594 SCR_013124 R/PIAGE, Power of Indirect Association Studies of Gene-Environment Interactions 2026-09-12 12:57:59 0
BOOST
 
Resource Report
Resource Website
10+ mentions
BOOST (RRID:SCR_013133) BOOST data analysis software, data processing software, software application, software resource Software application (entry from Genetic Analysis Software) for a method for detecting gene-gene interactions. It allows examining all pairwise interactions in genome-wide case-control studies. gene, genetic, genomic, logistic regression model, gene-gene interactions is listed by: Genetic Analysis Software Free, Available for download nlx_154249 SCR_013133 BOolean Operation based Screening and Testing 2026-09-12 12:57:59 33
Sequencing of Candida Albicans
 
Resource Report
Resource Website
10+ mentions
Sequencing of Candida Albicans (RRID:SCR_013437) data or information resource, portal, topical portal The Stanford Genome Technology Center began a whole genome shotgun sequencing of strain SC5314 of Candida albicans. After reaching its original goal of 1.5X mean coverage of the haploid genome (16Mb) in summer, 1998, Stanford was awarded a supplemental grant to continue sequencing up to a coverage of 10X, performing as much assembly of the sequence as possible, using recognizable genes as nucleation points. Candida albicans is one of the most commonly encountered human pathogens, causing a wide variety of infections ranging from mucosal infections in generally healthy persons to life-threatening systemic infections in individuals with impaired immunity. Oral and esophogeal Candida infections are frequently seen in AIDS patients. Few classes of drugs are effective against these fungal infections, and all of them have limitations with regard to efficacy and side-effects. stanford, genome, technology, shotgun, sequencing, strain, haploid, gene, nucleation, health, life, aids, drug, patient has parent organization: Stanford University; Stanford; California Burroughs Wellcome Fund ;
NIDCR DE12302-02S2;
NIAID RO1AI16567;
NIAID RO1AI46351;
NIAID NO1AI05406;
NIDCR R01DE12940;
NIDCR P01DE07946
nif-0000-30294 SCR_013437 Candida Albicans 2026-09-12 12:58:03 21
L2L Microarray Analysis Tool
 
Resource Report
Resource Website
1+ mentions
L2L Microarray Analysis Tool (RRID:SCR_013440) L2L analysis service resource, data analysis service, data analysis software, data or information resource, data processing software, data repository, database, production service resource, service resource, software application, software resource, storage service resource THIS RESOURCE IS NO LONGER IN SERVICE, documented May 10, 2017. A pilot effort that has developed a centralized, web-based biospecimen locator that presents biospecimens collected and stored at participating Arizona hospitals and biospecimen banks, which are available for acquisition and use by researchers. Researchers may use this site to browse, search and request biospecimens to use in qualified studies. The development of the ABL was guided by the Arizona Biospecimen Consortium (ABC), a consortium of hospitals and medical centers in the Phoenix area, and is now being piloted by this Consortium under the direction of ABRC. You may browse by type (cells, fluid, molecular, tissue) or disease. Common data elements decided by the ABC Standards Committee, based on data elements on the National Cancer Institute''s (NCI''s) Common Biorepository Model (CBM), are displayed. These describe the minimum set of data elements that the NCI determined were most important for a researcher to see about a biospecimen. The ABL currently does not display information on whether or not clinical data is available to accompany the biospecimens. However, a requester has the ability to solicit clinical data in the request. Once a request is approved, the biospecimen provider will contact the requester to discuss the request (and the requester''s questions) before finalizing the invoice and shipment. The ABL is available to the public to browse. In order to request biospecimens from the ABL, the researcher will be required to submit the requested required information. Upon submission of the information, shipment of the requested biospecimen(s) will be dependent on the scientific and institutional review approval. Account required. Registration is open to everyone.. Documented on August 26, 2019.

Database of published microarray gene expression data, and a software tool for comparing that published data to a user''''s own microarray results. It is very simple to use - all you need is a web browser and a list of the probes that went up or down in your experiment. If you find L2L useful please consider contributing your published data to the L2L Microarray Database in the form of list files. L2L finds true biological patterns in gene expression data by systematically comparing your own list of genes to lists of genes that have been experimentally determined to be co-expressed in response to a particular stimulus - in other words, published lists of microarray results. The patterns it finds can point to the underlying disease process or affected molecular function that actually generated the observed changed in gene expression. Its insights are far more systematic than critical gene analyses, and more biologically relevant than pure Gene Ontology-based analyses. The publications included in the L2L MDB initially reflected topics thought to be related to Cockayne syndrome: aging, cancer, and DNA damage. Since then, the scope of the publications included has expanded considerably, to include chromatin structure, immune and inflammatory mediators, the hypoxic response, adipogenesis, growth factors, hormones, cell cycle regulators, and others. Despite the parochial origins of the database, the wide range of topics covered will make L2L of general interest to any investigator using microarrays to study human biology. In addition to the L2L Microarray Database, L2L contains three sets of lists derived from Gene Ontology categories: Biological Process, Cellular Component, and Molecular Function. As with the L2L MDB, each GO sub-category is represented by a text file that contains annotation information and a list of the HUGO symbols of the genes assigned to that sub-category or any of its descendants. You don''''t need to download L2L to use it to analyze your microarray data. There is an easy-to-use web-based analysis tool, and you have the option of downloading your results so you can view them at any time on your own computer, using any web browser. However, if you prefer, the entire L2L project, and all of its components, can be downloaded from the download page. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible
microarray, gene expression, adipogenesis, biological, biological process, cancer, cell cycle regulator, cellular component, chromatin, cockayne syndrome, dna damage, growth factor, hormone, human biology, hypoxic response, immune mediator, inflammatory mediator, molecular function, molecular neuroanatomy resource, adipocyte, development, hypoxia, immune, inflammation, metabolism, mitogen, neuro, rna, vascular, transcription, tissue, splicing, mouse, human, rat, source code, statistical analysis, gene, chromatin structure is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of Washington; Seattle; USA
Cockayne syndrome, DNA damage, Other, Aging, Cancer Cora May Poncin Foundation ;
NIGMS GM41624
PMID:16168088 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10463 http://depts.washington.edu/l2l/about.html SCR_013440 L2L Microarray Database, L2L Microarray Analysis Tool: A simple tool for discovering the hidden biological significance in microarray expression data, L2L MDB 2026-09-12 12:58:03 1
PlasmoDB
 
Resource Report
Resource Website
1000+ mentions
PlasmoDB (RRID:SCR_013331) analysis service resource, data access protocol, data analysis service, data or information resource, data repository, database, production service resource, service resource, software resource, storage service resource, web service Functional genomic database for malaria parasites. Database for Plasmodium spp. Provides resource for data analysis and visualization in gene-by-gene or genome-wide scale. PlasmoDB 5.5 contains annotated genomes, evidence of transcription, proteomics evidence, protein function evidence, population biology and evolution data. Data can be queried by selecting from query grid or drop down menus. Results can be combined with each other on query history page. Search results can be downloaded with associated functional data and registered users can store their query history for future retrieval or analysis.Key community database for malaria researchers, intersecting many types of laboratory and computational data, aggregated by gene. Functional, genomic, database, malaria, parasite, data, analysis, visualization, gene, genome, annotation, transcription, proteomics, protein, evolution, FASEB list uses: SynView
is related to: GeneDB Pfalciparum
has parent organization: Eukaryotic Pathogen Database Resources
has parent organization: Pennsylvania State University
has parent organization: University of Georgia; Georgia; USA
malaria NIAID PMID:18957442 nif-0000-03314, SCR_017665, r3d100011569 SCR_013331 PlasmoDB, Plasmodium Genomics Resource, PlasmoDB 5.5, Plasmodium genome-resource 2026-09-12 12:58:02 1324
PiGenome
 
Resource Report
Resource Website
PiGenome (RRID:SCR_013394) PiGenome analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Database for ESTs (Expressed Sequence Tags), consensus sequences, bacterial artificial chromosome (BAC) clones, BES (BAC End Sequences). They have generated 69,545 ESTs from 6 full-length cDNA libraries (Porcine Abdominal Fat, Porcine Fat Cell, Porcine Loin Muscle, Liver and Pituitary gland). They have also identified a total of 182 BAC contigs from chromosome 6. It is very valuable resources to study porcine quantitative trait loci (QTL) mapping and genome study. Users can explore genomic alignment of various data types, including expressed sequence tags (ESTs), consensus sequences, singletons, QTL, Marker, UniGene and BAC clones by several options. To estimate the genomic location of sequence dataset, their data aligned BES (BAC End Sequences) instead of genomic sequence because Pig Genome has low-coverage sequencing data. Sus scrofa Genome Database mainly provide comparative map of four species (pig, cattle, dog and mouse) in chromosome 6. gene expression, genome, sequence, gene, expressed sequence tag, consensus sequence, bac clone, bac end sequence, bac contig, quantitative trait loci, singleton, marker, unigene, chromosome 6, blast, transcript, bacterial artificial chromosome, snp, alignment is related to: Gene Ontology
has parent organization: National Institute of Animal Science; Gyeonggi-do; South Korea
National Institute of Animal Science; Gyeonggi-do; Korea ;
Korean Rural Development Administration ;
Biogreen21 Project 20050301034467
PMID:19082661 nlx_153888 http://pigenome.nabc.go.kr/ SCR_013394 Sus scrofa Genome database, Pig Genome Database, Pigenome database 2026-09-12 12:58:02 0
ENIGMA
 
Resource Report
Resource Website
100+ mentions
ENIGMA (RRID:SCR_013400) data analysis software, data processing software, software application, software resource A software tool to extract gene expression modules from perturbational microarray data, based on the use of combinatorial statistics and graph-based clustering. The modules are further characterized by incorporating other data types, e.g. GO annotation, protein interactions and transcription factor binding information, and by suggesting regulators that might have an effect on the expression of (some of) the genes in the module. Version : ENIGMA 1.1 used GO annotation version : Aug 29th 2007 genome, gene, genetic software, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Ghent University; Ghent; Belgium
is parent organization of: ENIGMA-DTI Pipeline
PMID:18402676 biotools:enigma, nlx_144365 https://bio.tools/enigma SCR_013400 2026-09-12 12:58:02 133
R/FEST
 
Resource Report
Resource Website
1+ mentions
R/FEST (RRID:SCR_013347) software application, software resource An R package for simulations and likelihood calculations of pair-wise family relationships using DNA marker data. (entry from Genetic Analysis Software) gene, genetic, genomic, r is listed by: Genetic Analysis Software nlx_154111, SCR_000830, nlx_154582 SCR_013347 FEST 2026-09-12 12:58:02 2
Residual Variation Intolerance Score (RVIS)
 
Resource Report
Resource Website
1+ mentions
Residual Variation Intolerance Score (RVIS) (RRID:SCR_013850) RVIS data or information resource, narrative resource, standard specification A gene-based score intended to help in the interpretation of human sequence data. The score is designed to rank genes in terms of whether they have more or less common functional genetic variation relative to the genome wide expectation given the amount of apparently neutral variation the gene has. A gene with a positive score has more common functional variation, and a gene with a negative score has less and is referred to as intolerant. gene, score, sequence, interpretation, rank, functional genetic variation is listed by: Columbia University; New York; USA NIH Epi4K Sequencing ;
Bioinformatics and Biostatistics Core U01NS077303
DOI:10.1371/journal.pgen.1003709 SCR_013850 Residual Variation Intolerance Score 2026-09-12 12:58:10 8
RatsPub
 
Resource Report
Resource Website
RatsPub (RRID:SCR_018905) data access protocol, software application, software resource, text-mining software, web service Web service that conducts comprehensive literature mining to identify roles of genes in addiction. Searches PubMed to find abstracts containing genes of interest and list of curated addiction related keywords. Literature mining, addiction gene, PubMed abstract, gene, addiction, addiction relationship, neurogenetics NIDA P30 DA044223;
NIDA U01 DA047638
Free, Freely available https://github.com/chen42/ratspub SCR_018905 rats.pub, Rats.pub, Relationship with Addiction Through Searches of PubMed 2026-09-12 12:59:07 0
GOnet
 
Resource Report
Resource Website
1+ mentions
GOnet (RRID:SCR_018977) data access protocol, service resource, software resource, web service Web tool for interactive Gene Ontology analysis of any biological data sources resulting in gene or protein lists. Gene Ontology, interactive analysis, data, gene, protein, gene list, protein list, analysis, bio.tools is listed by: Debian
is listed by: bio.tools
works with: Gene Ontology
NHGRI R24 HG010032;
NIAID U19 AI118610;
NIAID U19 AI118626;
NIGMS ;
NIH Common Fund
PMID:30526489 biotools:GOnet https://github.com/mikpom/gonet, https://bio.tools/GOnet SCR_018977 2026-09-12 12:59:08 7
Glimmer-MG
 
Resource Report
Resource Website
1+ mentions
Glimmer-MG (RRID:SCR_011932) Glimmer-MG software resource A software system for finding genes in environmental shotgun DNA sequences. metagenomics, gene is listed by: OMICtools
is related to: Glimmer
has parent organization: University of Maryland; Maryland; USA
Open unspecified license, OSI certified OMICS_01487 SCR_011932 Glimmer-MG: Metagenomics Gene-Finding System, Gene Locator and Interpolated Markov ModelER - MetaGenomics 2026-09-12 12:57:42 9
Algal Functional Annotation Tool
 
Resource Report
Resource Website
Algal Functional Annotation Tool (RRID:SCR_012034) Algal Functional Annotation Tool analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Tools to search gene lists for functional term enrichment as well as to dynamically visualize proteins onto pathway maps. Additionally, integrated expression data may be used to discover similarly expressed genes based on a starting gene of interest. gene, pathway, visualization, annotation, function, protein family, ontology, protein, genomics is listed by: OMICtools
is related to: Gene Ontology
is related to: KEGG
is related to: MetaCyc
is related to: Reactome
is related to: Pfam
is related to: InterPro
has parent organization: University of California at Los Angeles; California; USA
DOE ;
NAABB ;
IGP ;
Air Force Office of Scientific Research
PMID:21749710 OMICS_02226 SCR_012034 2026-09-12 12:57:44 0
funRiceGenes
 
Resource Report
Resource Website
50+ mentions
funRiceGenes (RRID:SCR_015778) data or information resource, data set, database Dataset of functionally characterized rice genes and members of different gene families. The dataset was created by integrating data from available databases and reviewing publications of rice functional genomic studies. rice, functional genomics, interaction network, genetic improvement, gene, data integration National Key Research and Development Program of China 2016YFD0100903;
National Natural Science Foundation of China 31771873 and National Natural Science Foundation of China;
Outstanding Young Talents Program
Freely available, Public, Available for download, Free https://github.com/venyao/RICENCODE, http://funricegenes.ncpgr.cn/ SCR_015778 RICENCODE 2026-09-12 12:58:30 53
CluePedia Cytoscape plugin
 
Resource Report
Resource Website
100+ mentions
CluePedia Cytoscape plugin (RRID:SCR_015784) data analysis software, data processing software, data visualization software, software application, software resource Data analysis software and search tool for new markers potentially associated to pathways. CluePedia calculates linear and non-linear statistical dependencies from experimental data and investigates interrelations within each pathway to reveal associations through gene/protein/miRNA enrichments. cytoscape, cluepedia, search tool, marker, pathway, experimental data, in silico data, linear dependence, gene, protein, miRNA is a plug in for: Cytoscape INCa ;
Canceropole Ile de France ;
INSERM ;
MedImmune ;
Qatar National Research Fund NPRP09-1174-3-291;
European Commission 7FP Geninca 202230);
LabEx Immuno-Oncology
PMID:23325622 Free for non-profits, Free for academic use, Available for download, Commercially available, Available for purchase SCR_015784 CluePedia: A ClueGO plugin, CluePedia: A ClueGO plugin for pathway insights using integrated experimental and in silico data 2026-09-12 12:58:30 193
Piggy
 
Resource Report
Resource Website
10+ mentions
Piggy (RRID:SCR_015941) data analysis software, data processing software, software application, software resource Pipeline for analyzing intergenic regions in bacteria. It is designed to be used in conjunction with Roary (https://github.com/sanger-pathogens/Roary). intergenic, region, bacterial, analysis, gene, genome, assembly Medical Research Council Free, Available for download SCR_015941 2026-09-12 12:58:32 32
UK Brain Expression Consortium
 
Resource Report
Resource Website
1+ mentions
UK Brain Expression Consortium (RRID:SCR_015889) UKBEC consortium, data or information resource, organization portal, portal Consortium studying the regulation and alternative splicing of gene expression in multiple tissues from human brains. The UKBEC dataset comprises of brains from individuals free of neurodegenerative disorders. neurodegenerative, brain, disorder, mrna, dna, eqtl, snp, gene, visualization, expression is parent organization of: Braineac SCR_015889 2026-09-12 12:58:32 3
Barrnap
 
Resource Report
Resource Website
500+ mentions
Barrnap (RRID:SCR_015995) data analysis software, data processing software, sequence analysis software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software to predict the location of ribosomal RNA genes in genomes. It supports bacteria, archaea, mitochondria, and eukaryotes. It takes FASTA DNA sequence as input, writes GFF3 as output, and supports multithreading., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. multithreading, fasta, sequencing, software, predict, location, ribosomal, gene, genome, RNA, prediction, bacteria, archaea, mitochondria, eukaryote, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
THIS RESOURCE IS NO LONGER IN SERVICE biotools:barrnap, OMICS_13988 https://github.com/tseemann/barrnap, https://bio.tools/barrnap, https://sources.debian.org/src/barrnap/ SCR_015995 Barrnap: Basic rapid ribosomal RNA predictor 2026-09-12 12:58:33 722
National Gene Vector Laboratories
 
Resource Report
Resource Website
1+ mentions
National Gene Vector Laboratories (RRID:SCR_015944) NGVL data or information resource, portal, topical portal The National Gene Vector Laboratories (NGVL) was established as a cooperative national effort to produce and distribute vectors for human gene transfer studies. gene, therapy, manufacturing, toxicology, human, research, vector, transfer, study is used by: Adobe Illustrator NIH SCR_015944 2026-09-12 12:58:32 2

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