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http://cww.charite.de

Core Facility for the development and manufacturing of experimental medical devices. Offers advise on experimental design, draft technical proposals, and support in the realization of prototypes and patent ideas.

Proper citation: Charité Berlin University of Medicine Scientific Workshop Core Facility (RRID:SCR_028422) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/translational-imaging

Core provides specialized preclinical imaging services including image acquisition, quantitative image analysis, multidimensional renderings and data sets for research purposes.

Proper citation: Roswell Park Comprehensive Cancer Center Translational Imaging Shared Resource TISR Core Facility (RRID:SCR_028388) Copy   

•   Source: SciCrunch Registry

https://cancer.mcw.edu/researchers-and-clinicians/shared-resources/Biostatistics-Shared-Resource-BSSR

Core services include experimental design, sample size calculation, randomization, analysis plans, data analysis, grant and manuscript preparation, full clinical trial support, and innovative targeted methods development.

Proper citation: Medical College of Wisconsin Cancer Center Biostatistics Shared Resource Core Facility (RRID:SCR_028382) Copy   

•   Source: SciCrunch Registry

https://johnshopkins.ilab.agilent.com/service_center/show_external/6418/the_center_for_proteomics_discovery

Core facility that helps biomedical researchers design and execute proteomics (and metabolomics/lipidomics) studies from sample preparation and LC-MS/MS data acquisition to protein/PTM identification and quantification and advanced bioinformatics/statistical analysis. CPD supports workflows, including label-free (DIA/DDA) and TMT multiplexed quantitative proteomics, phosphoproteomics/other PTMs, targeted PRM, single-cell proteomics, spatial proteomics, cell-type-specific proteomics, thermal proteome profiling, and more.

Proper citation: Johns Hopkins University School of Medicine Center for Proteomics Discovery CPD Core Facility (RRID:SCR_028384) Copy   

•   Source: SciCrunch Registry

https://semc.nysbc.org

Provides advanced resources in structural biology. Offers access to instruments, including multiple transmission electron microscopes (TEMs) and cryo-FIB/SEM systems. Trains scientists, from beginners to experienced users, on sample preparation (plunge/high-pressure freezers) and advanced EM techniques. Helps researchers solve the 3D structures of proteins and cellular components at atomic resolution.

Proper citation: New York Structural Biology Center SEMC Core Facility (RRID:SCR_028358) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/bioanalytics-metabolomics-pharmacokinetics

Core provides highly sensitive measurements for an extensive array of chemotherapeutic agents and metabolites to support basic research and preclinical/clinical drug development.

Proper citation: Roswell Park Comprehensive Cancer Center Bioanalytics, Metabolomics and Pharmacokinetics Shared Resource BMPK Core Facility (RRID:SCR_028367) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/genomics

Core offers services including expert technical staff performing all aspects of sample preparation, QC, assay design and analysis. Provides integrated set of tools and services for genomic analysis. Expertise and services include clone generation, high throughput mapping, array technology development. Offers genomics platforms including data analysis, training and education on instruments and methodologies, complete discovery/screening to validation services, and full Laboratory Information Management System (LIMS) request, workflow and sample management.

Proper citation: Roswell Park Comprehensive Cancer Center Genomics Shared Resource GSR Core Facility (RRID:SCR_028368) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/large-animal-imaging-facility-core

Core facilitates advanced MR image-guided interventional and noninvasive procedures to support research across a broad range of disease areas, including neurodegenerative, cardiothoracic, and reproductive disorders. Imaging capabilities span structural MRI, diffusion imaging, DCE and ASL perfusion, spectroscopy, angiography, cardiac imaging, tissue elastography, functional imaging, flow quantification, and quantitative T1, T2, and T2* mapping.In collaboration with the Division of Veterinary Resources (DVR), we encourage investigators to consult with our teams on all scientific, medical, technical, and compliance aspects of studies involving large animal models. Investigators are expected to obtain Institutional Animal Care and Use Committee (IACUC) approval before initiating study activities. Core provides comprehensive data processing, post-processing, and quantitative image analysis support to help investigators extract meaningful outcomes from complex imaging datasets. These services include image reconstruction workflows, multimodal image registration, segmentation, volumetric and regional quantification, diffusion and tract-based analysis, spectroscopy processing, and development of customized pipelines tailored to specific study needs.Provides support in generating high-quality preliminary data for grant applications, instrument proposals, and translational research initiatives by helping design imaging strategies, optimize acquisition protocols, and deliver rigorous quantitative analyses that strengthen scientific aims.For larger research programs, the LAIF Core can assist with processing and managing large-scale imaging datasets to support longitudinal studies, multisubject analyses, and publication-ready results.

Proper citation: Children's Hospital of Philadelphia CHOP Large Animal Imaging Facility LAIF Core Facility (RRID:SCR_028404) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/small-animal-imaging-facility

Core serves CHOP researchers with translational imaging capabilities. Provided imaging platform integrates multiple modalities including MRI, PET, CT, Optical, and US for monitoring disease progression and therapeutic response in vivo in small animal models. Services include Selecting the optimal imaging modality, Design and optimization of acquisition protocols, Expert execution of in vivo imaging experiments, Training for new users on image acquisition, Advanced data analysis and project management.Provides technical expertise and translational capability.

Proper citation: Children's Hospital of Philadelphia CHOP Small Animal Imaging Facility SAIF Core Facility (RRID:SCR_028405) Copy   

•   Source: SciCrunch Registry

https://hollingscancercenter.musc.edu/research/shared-resources/cell-molecular-imaging

Core provides MUSC Hollings Cancer Center members with sophisticated equipment, technologies, training, and expertise required for successful, cell and tissue-based microscopic imaging and image analysis.Optical Microscopy Services include equipment and expertise to facilitate imaging of tissues and cells by Hollings members. Innovative Techniques service include development and application of new imaging techniques to meet the emerging scientific needs of Hollings members.Education and Training services include education, trainning, and consultation on imaging technologies that enable scientific discovery, including a biennial Charleston Workshop on Light Microscopy for the Biomedical Sciences, as well as a lecture series on cell and molecular imaging, especially as it relates to tumor biology.

Proper citation: Medical University of South Carolina Hollings Cancer Center Cell and Molecular Imaging Core Facility (RRID:SCR_028369) Copy   

•   Source: SciCrunch Registry

https://chop.ilab.agilent.com/sc/4962/clinical-vector-core/?tab=about

Core provides manufacturing of clinical and pre-clinical Adeno-Associated Virus (AAV) vectors of serotypes 1, 2, 5, 6, 8, 9, and Lentivirus (LV) vectors. Novel or modified serotypes will require development prior to scale-up. Products for clinical use are manufactured in compliance with Current Good Manufacturing Practices (cGMP) for Phase 1 and 2 clinical trials. To support pre-clinical work, including pharmacology and toxicology studies, core offers products manufactured using a GMP-comparable process. Research-grade products for proof-of- principle and bridging studies are also offered.Core Facility uses a patented vector production technology and a highly efficient purification process that uses combined column and gradient centrifugation-based process steps. This system has manufactured clinical-grade AAV vectors. Prior to the final release of the clinical vectors, the vector product is subjected to numerous tests to ensure quality. Core also provides federal regulatory documentation and necessary certifications.

Proper citation: Children's Hospital of Philadelphia CHOP Clinical Vector Characterization Core Facility (RRID:SCR_028402) Copy   

•   Source: SciCrunch Registry

https://www.chop.edu/centers-programs/clinical-vivo-gene-therapy

Core experts offers complex gene therapy trials. Ensures licensed gene therapies are available in our clinics.

Proper citation: Children's Hospital of Philadelphia CHOP Clinical In Vivo Gene Therapy Core Facility (RRID:SCR_028403) Copy   

•   Source: SciCrunch Registry

https://cal-cryo.berkeley.edu/

Core provides researchers with access to Cryo Electron Microscopes and related tools for high resolution structural biology imaging experiments.

Proper citation: University of California at Berkeley Cal-Cryo QB3-Berkeley Core Facility (RRID:SCR_028363) Copy   

•   Source: SciCrunch Registry

https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/refs/heads/main/PDF/SCR_028362.pdf

High-throughput, 32-spot Surface Plasmon Resonance (SPR) system. The "Pro" designation commonly used by Bruker highlights its capabilities, including 8 flow cells with 4 spots each, designed for rapid, label-free molecular interaction analysis. Used for the Real-Time, Label-Free characterization of molecular interactions.

Proper citation: Bruker Sierra SPR-32 Pro Analyzer (RRID:SCR_028362) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/cag-biorepository-core

Pediatric biobank, hosting more than 600,000 biological samples that have been genotyped or sequenced in CAGs CLIA and CAP-accredited high-throughput centers. This core offers services in DNA and RNA extraction and QC.

Proper citation: Children's Hospital of Philadelphia CHOP CAG Biorepository Core Facility (RRID:SCR_028399) Copy   

•   Source: SciCrunch Registry

https://www.medschool.umaryland.edu/cibr/core/confocal/

Core provides researchers with confocal imaging equipment to enable acquisition of high resolution images (both in vivo and in vitro). Offers training and assistance in the use of confocal microscopes. Optimization of data acquisition and image processing are both part of the training, thus enabling researchers to efficiently design studies, acquire image data and extract relevant data features.

Proper citation: University of Maryland Baltimore Confocal Microscopy Core Facility (RRID:SCR_028432) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/human-pluripotent-stem-cell-core

Core generates induced pluripotent stem cell (iPSC) lines from somatic cells including peripheral blood mononuclear cells and fibroblasts. The Core has established standard operating procedures for Pluripotent stem cell growth and maintenance, Genome editing technologies including CRISPR-CAS9 and Differentiation to germ layer and derivative tissues of interest. Provides enrichment training courses for investigators interested in learning how to work with pluripotent stem cells and/or establish the pluripotent stem cell technology in their own labs.

Proper citation: Children's Hospital of Philadelphia CHOP Human Pluripotent Stem Cell Core Facility (RRID:SCR_028390) Copy   

•   Source: SciCrunch Registry

https://www.fieldmuseum.org/science/centers-and-labs/elemental-analysis-facility

Core consists of an Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) laboratory, an X-ray Fluorescence laboratory, a Raman laboratory, and an optical mineralogy laboratory. Museum curators and researchers are using this instrumentation extensively to further research programs on early state expansion in the Andes, evolving social networks on the north coast of Papua New Guinea, the social dynamics of early village societies and the emergence of early states, African pre-industrial civilizations and, trade and exchange around the Indian Ocean (Laure Dussubieux). In addition to research conducted by Field Museum staff, the EAF collaborates with scientists from other institutions, bringing researchers and students from all over the country to The Field Museum to learn about compositional analysis of ancient materials to enhance their research on a very wide range of anthropological topics.

Proper citation: Field Museum of Natural History Elemental Analysis Core Facility (RRID:SCR_028396) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/transgenic

Transgenic Core at Childrens Hospital Research Institute, working in partnership with the University of Pennsylvania CRISPR Core Facility, build complex mouse and rat models,genetically manipulating the mouse and rat genome to meet specific research needs utilizing genetic engineering approaches. Core provides services for the generation and preservation of genetically altered mice or rats.

Proper citation: Children's Hospital of Philadelphia CHOP Transgenic Core Facility (RRID:SCR_028397) Copy   

•   Source: SciCrunch Registry

https://www.ucl.ac.uk/medical-sciences/divisions/cancer/translational-technology-platforms/pathology-translational-technology-platform

Facility provides a range of histology and tissue-based molecular services to research scientists within the UCL Cancer Institute and across UCL.The facility also maintains a range of equipment available for use by UCL researchers to support a range of projects involving human and animal samples. We work in close collaboration with the UCL / UCLH Biobank for Studying Health and Disease and the UCL/UCLH Cancer Biomarker Centre (CBC) which provides a framework for the governance of research involving human samples and supports researchers in meeting regulatory standards.

Proper citation: University College London Cancer Institute Pathology Translational Technology Platform TTP Core Facility (RRID:SCR_028430) Copy   

•   Source: SciCrunch Registry