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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioextract.org/GuestLogin
An open, web-based system designed to aid researchers in the analysis of genomic data by providing a platform for the creation of bioinformatic workflows. Scientific workflows are created within the system by recording tasks performed by the user. These tasks may include querying multiple, distributed data sources, saving query results as searchable data extracts, and executing local and web-accessible analytic tools. The series of recorded tasks can then be saved as a reproducible, sharable workflow available for subsequent execution with the original or modified inputs and parameter settings. Integrated data resources include interfaces to the National Center for Biotechnology Information (NCBI) nucleotide and protein databases, the European Molecular Biology Laboratory (EMBL-Bank) non-redundant nucleotide database, the Universal Protein Resource (UniProt), and the UniProt Reference Clusters (UniRef) database. The system offers access to numerous preinstalled, curated analytic tools and also provides researchers with the option of selecting computational tools from a large list of web services including the European Molecular Biology Open Software Suite (EMBOSS), BioMoby, and the Kyoto Encyclopedia of Genes and Genomes (KEGG). The system further allows users to integrate local command line tools residing on their own computers through a client-side Java applet.
Proper citation: BioExtract (RRID:SCR_005397) Copy
http://bioapps.sabanciuniv.edu/mugex/v02/
Service that automatically extracts mutation-gene pairs from MEDLINE abstracts for a given disease.
Proper citation: MuGeX (RRID:SCR_005306) Copy
http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/AnneOTate.cgi
A web based search tool to help you gain an overview of the set of articles (up to 25,000 most recent articles) retrieved by a PubMed query. Once you enter a query, you can select different types of summary information to view: Important words, Topics, Authors, Affiliations, Journals, Year, Clustered by topic.
Proper citation: Anne O'Tate (RRID:SCR_005340) Copy
http://agbase.msstate.edu/cgi-bin/tools/goprofiler_select.pl
Service that provides a summary of GO annotations available for each species. The user provides a taxon id and GOProfiler displays the number of GO associations and the number of annotated proteins for that species. The results are listed by evidence code and a separate list of unannotated proteins is also provided.
Proper citation: GOProfiler (RRID:SCR_005683) Copy
https://www.hpcwire.com/2005/10/28/swami_the_next_generation_biology_workbench/
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. The Next Generation Biology Workbench is a free resource for research and education in Bioinformatics, Genomics, Proteomics, and Phylogenetics. The NGBW is a re-engineering of the Biology Workbench which was designed by Shankar Subramaniam and his group to provide an integrated environment where tools, user data, and public data resources can be easily accessed. The NGBW is designed to be an organic tool that evolves with the needs of the Biomedical research and education communities. The Next Generation Biology Workbench (NGBW) is now available for public use, in its production release.
Proper citation: Swami: The Next Generation Biology Workbench (RRID:SCR_007217) Copy
http://www.proquest.com/en-US/products/dissertations/
ProQuest Dissertation Publishing has been publishing dissertations and theses since 1938. In that time, we have published over 2 million graduate works from graduate schools around the world. We have over 700 active university publishing partners, and publish more than 70,000 new graduate works each year. In addition to publishing, we provide access to graduate works for thousands of libraries around the world. Based on your interests, you should find the information you need below: * Authors - Information for authors on why and how to publish their graduate work with us. * Grad Schools & Libraries - Learn about the benefits of publishing, and why to submit online. * Researchers - We can help you find the dissertation or thesis you need.
Proper citation: ProQuest Dissertation Publishing (RRID:SCR_006075) Copy
http://vis.stanford.edu/wrangler/
Wrangler is an interactive tool for data cleaning and transformation. Spend less time formatting and more time analyzing your data. Why wrangle? * Too much time is spent manipulating data just to get analysis and visualization tools to read it. Wrangler is designed to accelerate this process: spend less time fighting with your data and more time learning from it. * Wrangler allows interactive transformation of messy, real-world data into the data tables analysis tools expect. Export data for use in Excel, R, Tableau, Protovis, ... * Want to learn more about Wrangler''s design? Take a look at our research paper. * Wrangler is still a work-in-progress. Please share your feedback and feature requests!
Proper citation: DataWrangler (RRID:SCR_006335) Copy
http://snps.ccbr.utoronto.ca:8080/SNPdryad/
Service to predict deleterious non-synonymous human Single Nucleotide Polymorphisms (SNPs) using only orthologous protein sequences.
Proper citation: SNPdryad (RRID:SCR_006414) Copy
http://www.biobase-international.com/product/genome-trax
Service that provides a comprehensive compilation of variant knowledge that allows you to identify pathogenic variants in human whole genome or exome sequences. It makes it easy to upload a complete genome?s worth of variations and identify the biologically relevant subset of known mutations, mutations that are novel and appear in a candidate disease genes, or mutations that are predicted to have a deleterious effect. The database includes a comprehensive collection of disease causing mutations from HGMD Professional, regulatory sites from TRANSFAC , and disease genes, drug targets and pathways from PROTEOME, as well as pharmacogenomic variants. It integrates the best public data-sets on somatic mutations, allele frequencies and clinical variants, in their most up-to-date version, for a total of more than 165 million annotations. It is possible to identify known pathogenic variants, remove harmless common variants, and obtain deleterious predictions for novel variants. With family data, it is possible to identify variants that are de novo, compound heterozygous only in the offspring. All of the results can be downloaded to Excel for further review. For core facilities and bioinformaticians, the complete underlying data is made available for download and easy integration into custom analysis pipelines. Genome Trax data is optimized to work with many other software packages, such as ANNOVARTM, CLC bio, Alamut, SimulConsult, and Cartagenia.
Proper citation: Genome Trax (RRID:SCR_001234) Copy
http://bionimbus.opensciencedatacloud.org/
A cloud-based infrastructure for managing, analyzing and sharing genomics datasets.
Proper citation: Bionimbus (RRID:SCR_001189) Copy
http://neuronalarchitects.com/about-the-workshop.html
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 17, 2016. Statistical and biomedical informatics software studio that develops neuroscience applications and brain computer interface games. They are dedicated to the integration of medical research, neuroscience, time series analysis, computer programming, statistics, sensor technologies, graphics design, artificial intelligence and entertainment to build gaming systems for neuroscientific research and intelligent tutoring in the classroom and lab. The current focus of The Cromwell Workshop/Neuronal Architects is on theoretical neuroscience and experimental modeling of psychological and neural processes that involve attention, emotion, motivation and executive functions that are impaired by neurological diseases. The outcome of this work is to use these results in the design of multiple genre brain computer interface gaming systems that can be used in both clinical and at home settings. If you would like to explore any collaborative opportunities to use their software or enhance your existing statistical products with their .NET, Java, R and Matlab code bases, let them know.
Proper citation: The Cromwell Workshop (RRID:SCR_001588) Copy
A free online service to easily create and share webpages.
Proper citation: Google Sites (RRID:SCR_000112) Copy
http://www.scienceexchange.com/facilities/genomics-services-lab
A lab that offers genetic research tools such as RNA sequencing and a variety of arrays.
Proper citation: HudsonAlpha Genomics Services Lab (RRID:SCR_000353) Copy
http://www.scienceexchange.com/facilities/ksf-labs
THIS RESOURCE IS NO LONGER IN SERVICE, documented on February 3rd, 2022. KSF Labs is the virtual/real workshop(s).
Proper citation: KSF Labs (RRID:SCR_010987) Copy
http://www.allseq.com/default.aspx
Free online tools to find the best Sequencing Service provider for your project.
Proper citation: AllSeq (RRID:SCR_010053) Copy
http://helixweb.nih.gov/dnaworks
DNAWorks automates the design of oligonucleotides for gene synthesis by PCR-based methods. The availability of sequences of entire genomes has dramatically increased the number of protein targets, many of which will need to be overexpressed in cells other than the original source of DNA. Gene synthesis often provides a fast and economically efficient approach. The synthetic gene can be optimized for expression and constructed for easy mutational manipulation without regard to the parent genome. DNAWorks accesses a computer program that automates the design of oligonucleotides for gene synthesis. The website provides forms for simple input information, i.e. amino acid sequence of the target protein and melting temperature (needed for the gene assembly) of synthetic oligonucleotides. The program outputs a series of oligonucleotide sequences with codons optimized for expression in an organism of choice. Those oligonucleotides are characterized by highly homogeneous melting temperatures and a minimized tendency for hairpin formation. The approach presented here simplifies the production of proteins from a wide variety of organisms for genomics-based studies.
Proper citation: DNAWorks at Helix Systems (RRID:SCR_008470) Copy
http://www.sanger.ac.uk/cgi-bin/blast/submitblast/d_rerio
This Blast server offers searches against all D. rerio finished and unfinished clones in the Sanger sequencing pipeline. You can now also search the de novo assemblies generated from sequencing of one doubled haploid homozygous individual of each the AB and Tuebingen strain. Both fish were sequenced to ~40x coverage using Illumina GA sequencing technology and the sequences were assembled using Phusion2, resulting in a 1,33 Gb AB and a 1.48 Gb Tuebingen assembly. Due to the short reads and short inserts and no integration of physical or genetic map data, both assemblies are highly fragmented - with an N50 contig size of about 5kb. Mis-assembly errors may also be present in the contigs. Please note these assemblies are independent additions to the assemblies released by the zebrafish genome project and are intended to aid identification of polymorphisms between these two strains. Charity. Genome Research Limited is a charity registered in England with number 1021457
Proper citation: D. rerio Blast Server (RRID:SCR_008461) Copy
https://www.microbialtec.com/aerobic-cultivation.html
Aerobic cultivation services to culture various microorganisms that can be isolated from readily available sources.
Proper citation: Creative Biogene Aerobic Cultivation Service Resource (RRID:SCR_022099) Copy
https://www.microbialtec.com/strain-anaerobic-culture.html
Service for anaerobic bacteria cultivation and culture using variety of culture media and culture conditions. Includes collection, strain cultivation, isolation, identification and strain preservation.
Proper citation: Creative Biogene Strain Anaerobic Culture Service Resource (RRID:SCR_022097) Copy
https://pna.creative-peptides.com/services/synthesis-by-fmoc-chemistry.html
Provides Fmoc based PNA synthesis. Route consists of repeated cycles of deprotection, activation, coupling and capping.Synthesis of small scale PNA oligomers, which can be performed on common DNA synthesis platforms.
Proper citation: Creative Peptides Chemical Synthesis of PNA Oligomers with Fmoc Service Resource (RRID:SCR_022132) Copy
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