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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://harvard.eagle-i.net/i/0000012e-58c7-d44f-55da-381e80000000
Core to provide gene expression data analysis service. Activities range from the provision of services to fully collaborative grant funded investigations.
Proper citation: Harvard Partners HealthCare Center for Personalized Genetic Medicine Bioinformatics Core Facility (RRID:SCR_000882) Copy
http://www.scienceexchange.com/facilities/4904
A contract research organization based in India that provides services including Clinical Development, Contract Manufacturing and Informatics.
Proper citation: GVK Biosciences Labs and Facilities (RRID:SCR_001044) Copy
http://www.ohri.ca/FacilitiesAndServices/
Portal to research facilities and services within the Ottawa Hospital Research Institute. Facilities and services include access to their bioinformatics facility, flow cytometry facility, human pluripotent stem cell facility, and their clinical research lab.
Proper citation: Ottawa Hospital Research Institute Labs and Facilities (RRID:SCR_001045) Copy
http://www.alliancegenome.org/
Organization that aims to develop and maintain sustainable genome information resources to promote understanding of the genetic and genomic basis of human biology, health, and disease. The Alliance is composed of FlyBase, Mouse Genome Database (MGD), the Gene Ontology Consortium (GOC), Saccharomyces Genome Database (SGD), Rat Genome Database (RGD), WormBase, and the Zebrafish Information Network (ZFIN).
Proper citation: Alliance of Genome Resources (RRID:SCR_015850) Copy
http://www.lajollaneuroscience.org/
Our NINDS Center Core Grant supports centralized resources and facilities shared by investigators with existing NINDS-funded research projects. Our Center is composed of three research cores, each of which will enrich the effectiveness of ongoing research, and promote new research directions. The three Core facilities support Electrophysiology, Neuropathology / Histology, and High-Throughput/High-Content Chemical and Genomic Library screening. By making these important Core Services available to the local Neuroscience community, the La Jolla Neurosciences Program hopes to promote the study of how the nervous system works and develop treatments for nervous system diseases. The cores and their services are available to La Jolla neuroscientists. Core services are available to NINDS-supported neuroscience projects from local investigators as well as young neuroscientists prior to obtaining their first NIH-funded grant. * Electrophysiology: SBMRI Electrophysiology ** The Electrophysiology Core consists of the Sanford-Burnham Electrophysiology Facility. This facility can perform patch-clamp intracellular and extracellular field recordings on a range of material including cultured cells and brain slices. The Sanford-Burnham facility emphasizes electrophysiological analysis of cultured cells and the detailed electrical properties of channels, receptors and recombinant proteins expressed in Xenopus oocytes or mammalian cells. * Neuropathology: UCSD Neuropathology ** The Neuropathology laboratory applies immunocytochemistry, neurochemistry, molecular genetics, transgenic models of disease, and imaging by scanning laser confocal microscopy to analysis of neurological disease in animal models. * Chemical Library Screening: SBIMR Assay Development, SBIMR Chemical Library Screening, SBIMR Cheminformatics, SBIMR High-content Screening ** The Chemical Library Screening core offers high-throughput screening (HTS) of biochemical and cell-based array using traditional HTS readouts and automated microscopy for high-content screening (HCS)> These facilities also offer array development and screening, as well as cheminformatics and medicinal chemistry.
Proper citation: La Jolla Interdisciplinary Neurosciences Center (RRID:SCR_002772) Copy
http://web.mit.edu/Edgerton/www/HighSpeed.html
The MIT Edgerton Center carries on the legacy of Doc Edgerton''s research and teaching by providing the Institute with a continuing expertise in high-speed and scientific imaging. Our facilities include a large studio space, a photographic darkroom, and a digital imaging studio equipped with an array of scanners, digital cameras, printers and plotters, and Macintosh computers. In addition, we have several technical digital cameras, including: * Redlake MASD PCI Motionscope, monochrome high-speed video at up to 8,000 images per second. * Concurrent analog data acquisition via a National Instruments A/D card. * Midas 2.0 motion analysis software from Xcitex, Inc. * NAC Model color high-speed camera (in process of donation). * Redlake MASD Ektapro 1012 high-speed video, monochrome, up to 12,000 images per second. * Redlake MASD Megaplus 1.4i scientific still camera These systems are available for use by interested MIT researchers and instructors, and by students pursuing hands-on projects. Each summer we offer a week-long course on high-speed imaging through the MIT Professional Institute. This subject (6.51s) is designed for scientists, engineers, and photographers who need to gather data on rapidly moving subjects and events for study, motion analysis, and trouble-shooting. Mornings are spent in the lecture hall learning the fundamentals for lighting, imaging technologies, and motion analysis. Afternoons are spent making high-speed images in the laboratory. For MIT students, we offer the popular Strobe Project Lab (6.163) to 24 students each term, where students learn the fundamentals of high-speed imaging and apply these techniques to final projects of their own choosing. Two subjects are offered that investigate digital imaging and image manipulation, SP.757 in Fall terms, and SP.747 in Spring terms.
Proper citation: Edgerton Center High Speed Imaging (RRID:SCR_005960) Copy
Biomedical technology research center that creates optimal facilities and environments and support for macromolecular structure determination by synchrotron X-ray diffraction at the National Synchrotron Light Source for the benefit of outside and in-house investigators. The PXRR innovates new access modes such as Mail-in crystallography, builds new facilities, currently on the X25 undulator, advances automation, develops remote participation software, collaborates with outside groups, teaches novice users, and supports vising investigators with 7-day, 20-hours staff coverage.
Proper citation: Macromolecular Crystallography Research Resource (RRID:SCR_001442) Copy
Biomedical technology research center that provides state-of-the-art surface analysis expertise, instrumentation, experimental protocols, and data analysis methods to address surface-related biomedical problems. NESAC/BIO develops and applies surface science methodologies that produce a full understanding of the surface composition, structure, spatial distribution, and orientation of biomaterials and adsorbed biomolecules. The NESAC/BIO program identifies areas where surface science must evolve to keep pace with the growth in biochemical knowledge and biomaterial fabrication technology, and develops instrumentation, experimental protocols, and data analysis methods to achieve this evolution. NESAC/BIO provides state-of-the-art surface analysis tools to researchers in the biomedical community. You can gain access to the NESAC/BIO facilities in one of the following ways: * Collaborative: Propose a project to collaborate on with NESAC/BIO. The project should be rewarding for both groups, and the results should reflect the utility of surface analysis for biomedical research * Service: Ask NESAC/BIO to analyze your biomaterial specimens. The spectra obtained from the analyses will be interpreted for you. * Training: Visit the University of Washington to receive training in surface analysis and personally run experiments for your individual research projects. These experiments should have a high probability for yielding useful information and should not involve the development of new ESCA techniques or methodologies.
Proper citation: National ESCA and Surface Analysis Center for Biomedical Problems (RRID:SCR_001430) Copy
http://start.sampleofscience.com
THIS RESOURCE IS NO LONGER IN SERVICE.
Free access service resource dedicated to connect researchers creating scientific samples with scientists who need samples for their experiments. With Sample of Science researchers can submit samples, or contact scientists proposing sample for dissemination. Each disseminated sample also gets its description published in Sample of Science Bulletin, a dedicated open access journal. It acquires a Digital Object Identifier (DOI) and becomes a fully citable item. Because both adequate sample descriptions and mutually-agreed dissemination conditions are key factors for a fruitful dissemination that respects mutual interest, Sample of Science provides tools to elaborate, communicate, discuss, and refine both sample description and dissemination conditions. This process, termed peer-adoption process, results in the publication of disseminated sample descriptions in Sample of Science Bulletin, a dedicated open access publication. The publication in Sample of Science Bulletin is useful to provide adequate recognition to Sample Authors who contribute to the development of science by offering visibility to their disseminated samples. To the adopter it provides experimental details regarding the sample under the form of a citable reference useful for any future publications involving this sample. To a larger scientific community interested in material science, it provides a useful tool to stay abreast the activity of sample providers in their respective field of expertise.
Proper citation: Sample of Science (RRID:SCR_001656) Copy
https://med.stanford.edu/sfgf.html
Stanford Genomics formerly Stanford Functional Genomics Facility provides services for high throughput sequencing, single cell assays, gene expression and genotyping studies utilizing microarray and real time PCR, and related services. High throughput sequencing (Illumina HiSeq 4000, NextSeq 500, MiSeq and MiniSeq), microarray gene expression and genotyping services (Affymetrix, Agilent and Illumina). Provides 24/7 access to instruments, equipment and software utilized within genomics field.
Proper citation: Stanford Genomics Service Center Core Facility (RRID:SCR_002050) Copy
Center whose interests and activities encompass several facets of gastrointestinal regulatory physiology and cell biology. It provides an infrastructure to support basic, translational and clinical research and to facilitate interdisciplinary research and training activities in digestive diseases.
Proper citation: CURE - Digestive Diseases Research Center (RRID:SCR_004238) Copy
http://www.biomedcentral.com/developingcountries/
Free, immediate and permanent online access to the full text of all articles published within its portfolio of over 200 peer-reviewed journals, and through its open access waiver fund, ensuring that scientific authors in low-income countries do not face financial barriers to publishing in open access journals. Open access provides a way for researchers from low-income countries to participate more fully in the international research community, and so BioMed Central has created a set of initiatives designed to increase the visibility and output of scientific research from these countries.
Proper citation: Open Access and the developing world (RRID:SCR_006672) Copy
https://www.ohsu.edu/transgenic-mouse-models-core
Core assists investigators with developing genetically engineered rodent models of human diseases for studying mutant genes and investigating molecular mechanisms underlying pathological processes.
Proper citation: OHSU Transgenic Mouse Models Core Facility (RRID:SCR_009994) Copy
https://ualr.edu/bioinformatics/midsouth-bioinformatics-center/
Core provides bioinformatics consulting, training, technical assistance, and access to computational infrastructure for faculty, students, and researchers in region with their bioscience computational needs. Offers private sessions, workshops and training on specialty topics. Computing resources including software, computing cluster, technical advice.
Proper citation: University of Arkansas at Little Rock MidSouth Bioinformatics Center Core Facility (RRID:SCR_017168) Copy
http://harvard.eagle-i.net/i/0000012d-56f2-62b7-2162-17a280000000
Core facility that provides the following services: Ultrasound/sonography access service. Ultrasound, which is also known as sonography, is a painless, non-invasive imaging technique that lets us look inside your child''s body without the use of radiation. It uses high-frequency sound waves to create pictures of organs, bones, tissues and blood vessels.
Proper citation: CHB Ultrasound (RRID:SCR_009608) Copy
http://cau.eagle-i.net/i/00000135-abef-4d3d-ecf8-187780000000
We are equipped for proteomics research including Cell Fractionation on one floor and tabletop Ultracentrifuges (Beckman Coulter) , Fast Protein Liquid Chromatography (FPLC), Two-Dimensional Protein Electrophoresis (Protean II, Biorad), and Gel Documentation Systems (one Bio-Rad and one Fuji Medical). Protein quantification can be done using UV-Vis spectrophotometry ( DU650, Beckman Coulter) or multimode Plate Spectrophotometers in both 96-well and 384-well micro well plate formats. Protein gels can also be visualized, digitized, and documented on Multi-Mode Imager Typhoon 9410.
Proper citation: CAU CCRTD-Proteomics (RRID:SCR_009687) Copy
http://harvard.eagle-i.net/i/0000012e-e30c-f348-cb22-be8c80000000
Core facility that provides the following services: Immunoassay expertise for several methodologies, Specialty hormone analysis. The Specialty Assay Research Core Lab (CLIA certified laboratory) is an analytical research core designed to provide scientific and analytical services to the Partners and non-Partners research communities. The primary objective of the core is to provide sensitive, cost-effective, and reproducible clinical research assays to investigators for endocrine, diabetes, bone markers, inflammatory and sleep medicine related research in both human and animal clinical research protocols. The core hopes to collaborate with investigators in biomarkers discovery and to offer new tools to the scientific community. The core also serves as a central laboratory for multisite studies. The SARC facility offers tests for any investigators (local or national) or industry, but preference may be given to internal users. Different rates may apply.
Proper citation: BWH Specialty Assay Research Core Laboratory (RRID:SCR_009686) Copy
http://harvard.eagle-i.net/i/0000013c-2506-8388-e81d-064c80000000
Core facility that provides the following services: PSG Procedures, PSG Data Archiving, PSG Training to Staff, PSG Data Processing and Analysis Support. The Sleep & EEG Core within the Division of Sleep Medicine (DSM) provides an integrated infrastructure and knowledge base in support of research projects that use polysomnography (PSG), quantitative EEG analysis and related methodologies. The Core consists of a team of specialists lead by the Core director and a chief PSG technologist. The Core provides support and services in different areas: # It provides basic training and certification in PSG and EEG instrumentation to technicians and investigators, particularly those conducting studies at the Center for Clinical Investigation (CCI) at Brigham and Women?s Hospital. # It acts as liaison between DSM investigators and CCI technical staff, and implements and monitors quality assurance measures. # It carries out standard vigilance state scoring of PSG recordings and different types of waking EEG and electrooculogram analyses. # It carries out spectral analysis of sleep and waking EEG. # It evaluates, acquires, and maintains PSG and EEG equipment used by investigators of the CCI. # It carries out PSG procedures such as sleep screens and multiple sleep latency tests. # It assists investigators in the analysis and interpretation of sleep and EEG data. Over the years, the Sleep & EEG Core has been a central part of many projects funded by NIH, the Air Force Office of Scientific Research (AFOSR), and the National Space Biomedical Research Institute (NSBRI) that had a main focus on the physiology of human sleep-wake regulation. Scientifically, the Core has contributed by providing investigators with important quantitative measures of homeostatic and circadian components of the human sleep-wake regulatory system.
Proper citation: BWH Sleep and EEG Core (RRID:SCR_009684) Copy
http://harvard.eagle-i.net/i/0000012c-742b-7e73-c437-ff0b80000000
Core facility that provides the following services: DNA sequencing, Multiplex ligation-dependent probe amplification analysis, Capillary electrophoresis.
The DNA Sequencing Core mission is to provide a highly accurate, high quality DNA sequencing service to the BWH community and other users. Our turn-around-time is 36 to 72 hrs.
Proper citation: BWH DNA Sequencing Core (RRID:SCR_009682) Copy
http://harvard.eagle-i.net/i/0000013c-fd63-dfbb-ea7a-a3a980000000
Core facility that provides the following services: Circulating Tumor Cell analysis, Circulating Tumor Cell Purification. The Circulating Tumor Cell Core Facility uses immunomagnetic technology developed by Veridex, LLC (Raritan, NJ) to isolate rare tumor cells from whole blood. Isolated tumor cells can then be counted or used for downstream analysis such as molecular studies or flow cytometry.
Proper citation: BWH Circulating Tumor Cell Core (RRID:SCR_008258) Copy
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