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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Software toolbox for quantitative MRI in neuroscience and clinical research. Open source and flexible tool for qMRI data handling and processing. Allows estimation of high quality multi parameter qMRI maps followed by spatial registration in common space for statistical analysis.
Proper citation: hMRI-toolbox (RRID:SCR_017682) Copy
Software distribution management for life sciences. Channel for Conda package manager specializing in bioinformatics software. Consists of repository of recipes hosted on GitHub, build system turning these recipes into conda packages, repository of packages containing bioinformatics packages ready to use with conda install.
Proper citation: BioConda (RRID:SCR_018316) Copy
https://github.com/HMPNK/CSA2.6
Software pipeline for high-throughput chromosome level vertebrate genome assembly. Pipeline, which after contig assembly performs post assembly improvements by ordering assembly and closing gaps, as well as splitting of low supported regions.
Proper citation: Chromosome Scale Assembler (RRID:SCR_017960) Copy
https://deeptools.readthedocs.io/en/develop/
Python based tools to process, visualize and analyse high-throughput sequencing data, such as ChIP-seq, RNA-seq or MNase-seq. Implemented within Galaxy framework. Used to perform complete bioinformatic workflows ranging from quality controls and normalizations of aligned reads to integrative analyses, including clustering and visualization approaches.
Proper citation: Deeptools (RRID:SCR_016366) Copy
https://crispr.cos.uni-heidelberg.de/
Web tool for CRISPR/Cas9 target prediction. Identifies and ranks all candidate sgRNA target sites according to their off-target quality and displays full documentation.
Proper citation: CCTop (RRID:SCR_016890) Copy
https://github.com/theislab/scanpy
Software Python tool for large scale single cell gene expression data analysis. Integrates analysis possibilities of established R-based frameworks, provides pre processing, visualization, graph-drawing and diffusion maps, clustering, identification of marker genes for clusters via differential expression tests and pseudo temporal ordering via diffusion pseudo time.
Proper citation: scanpy (RRID:SCR_018139) Copy
https://www2.hhu.de/rna/html/hexplorer_score.php
Web tool for genomic HEXploring allows landscaping of novel potential splicing regulatory elements. Allows landscaping of splicing regulatory regions, provides quantitative measure of mutation effects on splice enhancing and silencing properties and permitts calculation of mutationally most effective nucleotide.
Proper citation: HEXplorer score (RRID:SCR_022269) Copy
https://github.com/FRED-2/OptiType
Software tool for precision HLA typing from next generation sequencing data.
Proper citation: OptiType (RRID:SCR_022279) Copy
http://rna.informatik.uni-freiburg.de/MutaRNA/Input.jsp
Web server predicts and visualizes mutation induced structure changes of single nucleotide polymorphism in RNA sequence. This covers changes in accessibility (single strandedness) of molecule, its intra molecular base pairing potential and its base pairing probabilities. One of Freiburg RNA tools.
Proper citation: MutaRNA (RRID:SCR_021723) Copy
Software tool for analysis of non-covalent interactions in molecular dynamics trajectories. Implemented in Python and is universally applicable to any kind of MD trajectory supported by MDAnalysis package.
Proper citation: PyContact (RRID:SCR_025066) Copy
https://pubmed.ncbi.nlm.nih.gov/36123081/
Behavior change intervention software. Participants enter their data as part of online survey, and software generates individualized feedback letters.
Proper citation: PAL:Proactive Automatized Lifestyle intervention (RRID:SCR_025727) Copy
https://github.com/BackofenLab/HVSeeker/tree/main
Software tool for distinguishing between bacterial and phage sequences. Consists of two separate models: one analyzing DNA sequences and the other focusing on proteins.
Proper citation: HVSeeker (RRID:SCR_026120) Copy
https://themilolab.github.io/SPATA2/
Software package provides framework of functions and shiny-applications to work with spatial expression data. Used for spatial transcriptomics analysis.
Proper citation: SPATA2 (RRID:SCR_026167) Copy
https://bioconductor.org/packages/rrvgo/
Software R package to reduce and visualize Gene Ontology terms. Used for interpreting lists of Gene Ontology terms.
Proper citation: rrvgo (RRID:SCR_026680) Copy
https://github.com/AMICI-dev/AMICI/
Software toolbox implemented in C++/Python/MATLAB that provides efficient simulation and sensitivity analysis routines tailored for scalable, gradient-based parameter estimation and uncertainty quantification. Used for high-performance sensitivity analysis for large ordinary differential equation models.
Proper citation: AMICI (RRID:SCR_026913) Copy
A software application which assists in managing and sharing scientific literature. Users can collect and share publications, collaborate with other researchers, and find new resources and publications for research.
Proper citation: BibSonomy (RRID:SCR_013756) Copy
https://masst.gnps2.org/microbemasst/
Web taxonomically informed mass spectrometry search tool, tackles limited microbial metabolite annotation in untargeted metabolomics experiments. Leveraging database of over 60,000 microbial monocultures, users can search known and unknown MS/MS spectra and link them to their respective microbial producers via MS/MS fragmentation patterns.
Proper citation: microbeMASST (RRID:SCR_024713) Copy
https://sites.google.com/site/tdtdecodingtoolbox/
Software Matlab toolbox for multivariate analysis of functional and structural MRI data. Software package for multivariate analyses of functional imaging data.
Proper citation: The Decoding Toolbox (RRID:SCR_017424) Copy
https://github.com/theislab/anndata
Software tool that provides scalable way of keeping track of data and learned annotations. Initially built for Scanpy. Used as generic class for handling annotated data matrices. Stores data matrix with annotations of observations (samples, cells) and variables (features, genes), and unstructured annotations.
Proper citation: Anndata (RRID:SCR_018209) Copy
https://cadd.gs.washington.edu/
Web tool for predicting deleteriousness of variants throughout human genome. Software tool for scoring deleteriousness of single nucleotide variants as well as insertion and deletions variants in human genome.
Proper citation: Combined Annotation Dependent Depletion (RRID:SCR_018393) Copy
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