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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Myrna
 
Resource Report
Resource Website
1+ mentions
Myrna (RRID:SCR_006951) Myrna software resource A cloud computing tool for calculating differential gene expression in large RNA-seq datasets. It uses Bowtie for short read alignment and R/Bioconductor for interval calculations, normalization, and statistical testing. These tools are combined in an automatic, parallel pipeline that runs in the cloud (Elastic MapReduce in this case) on a local Hadoop cluster, or on a single computer, exploiting multiple computers and CPUs wherever possible. mapreduce, hadoop, cloud computing, differential expression, gene expression, rna-seq, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: ReCount - A multi-experiment resource of analysis-ready RNA-seq gene count datasets
has parent organization: Johns Hopkins University; Maryland; USA
PMID:20701754 Artistic License OMICS_01310, biotools:myrna https://github.com/BenLangmead/myrna
https://bio.tools/myrna
SCR_006951 Myrna: Cloud-scale differential gene expression for RNA-seq 2025-04-19 06:43:49 1
iFad
 
Resource Report
Resource Website
iFad (RRID:SCR_000271) iFad software resource An R software package implementing a bayesian sparse factor model for the joint analysis of paired datasets, the gene expression and drug sensitivity profiles, measured across the same panel of samples, e.g. cell lines. r, gene expression, drug sensitivity, analysis, drug-pathway association, gene-pathway, pathway, gene, drug is listed by: OMICtools
has parent organization: Yale School of Medicine; Connecticut; USA
PMID:22581178 Free, Public OMICS_01959 SCR_000271 2025-04-19 06:39:38 0
Mfuzz
 
Resource Report
Resource Website
10+ mentions
Mfuzz (RRID:SCR_000523) software resource Software package for noise-robust soft clustering of gene expression time-series data (including a graphical user interface). r, time series, gene expression, clustering, microarray, preprocessing, time course, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Humboldt University of Berlin; Berlin; Germany
has parent organization: Bioconductor
PMID:18084642 GNU General Public License, v2 biotools:mfuzz, OMICS_02012 https://bio.tools/mfuzz http://itb.biologie.hu-berlin.de/~futschik/software/R/Mfuzz/ SCR_000523 Mfuzz - Soft clustering of time series gene expression data 2025-04-19 06:39:53 11
GobyWeb
 
Resource Report
Resource Website
1+ mentions
GobyWeb (RRID:SCR_005443) GobyWeb software resource Web application that facilitates the management and analysis of high-throughput sequencing (HTS) data. In the back-end, it uses the Goby framework, BWA, STAR, Last, GSNAP, Samtools, VCF-tools, along with a cluster of servers to provide rapid alignment and efficient analyses. GobyWeb makes it possible to analyze hundreds of samples in consistent ways without having to use command line tools. GobyWeb provides tools that streamline frequent data analyses for RNA-Seq, Methyl-Seq, RRBS, or DNA-Seq datasets and to enable teams of investigators to share reads and results of analyses. GobyWeb can be extended for new analyses by developing plugins. high-throughput sequencing, gene expression, dna methylation, sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Weill Cornell Medical College; New York; USA
PMID:23936070 Acknowledgement requested, GNU Lesser General Public License, v3 OMICS_00601, biotools:gobyweb https://bio.tools/gobyweb SCR_005443 2025-04-19 06:42:51 3
netClass
 
Resource Report
Resource Website
netClass (RRID:SCR_005672) netClass software resource An R package for network-based feature (gene) selection for biomarkers discovery via integrating biological information. The package adapts the following 5 algorithms for classifying and predicting gene expression data using prior knowledge: # average gene expression of pathway (aep); # pathway activities classification (PAC); # Hub network classification (hubc); # filter via top ranked genes (FrSVM); # network smoothed t-statistic (stSVM). protein-protein interaction network, biomarker discovery, classification, micoarray, gene expression profile, protein-protein interaction, gene expression, gene, biomarker is listed by: OMICtools
has parent organization: SourceForge
PMID:24443376 Free, Public OMICS_02241 SCR_005672 2025-04-19 06:42:58 0
ChIPXpress
 
Resource Report
Resource Website
1+ mentions
ChIPXpress (RRID:SCR_006653) ChIPXpress software resource A R package designed to improve ChIP-seq and ChIP-chip target gene ranking using publicly available gene expression data. It takes as input predicted transcription factor (TF) bound genes from ChIPx data and uses a corresponding database of gene expression profiles downloaded from NCBI GEO to rank the TF bound targets in order of which gene is most likely to be functional TF target. gene expression, chip-seq, chip-chip, transcription factor, target gene, gene, gene expression profile is listed by: OMICtools
is related to: Gene Expression Omnibus
has parent organization: Bioconductor
GNU General Public License, v2 or greater OMICS_00516 SCR_006653 ChIPXpress: enhanced transcription factor target gene identification from ChIP-seq and ChIP-chip data using publicly available gene expression profiles 2025-04-19 06:43:40 2
Pathview
 
Resource Report
Resource Website
100+ mentions
Pathview (RRID:SCR_002732) software resource A tool set for pathway-based data integration and visualization. It maps and renders a wide variety of biological data on relevant pathway graphs. All users need is to supply their data and specify the target pathway. Pathview automatically downloads the pathway graph data, parses the data file, maps user data to the pathway, and render pathway graph with the mapped data. In addition, Pathview also seamlessly integrates with pathway and gene set (enrichment) analysis tools for large-scale and fully automated analysis. software package, r, differential expression, gene expression, gene set enrichment, genetics, graph, network, metabolomics, microarray, pathway, proteomics, rna-seq, sequencing, systems biology, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23740750 GNU General Public License, v3 or greater biotools:pathview, OMICS_05212 http://pathview.r-forge.r-project.org/
https://bio.tools/pathview
SCR_002732 path view 2025-04-19 06:41:19 453
SASqPCR
 
Resource Report
Resource Website
1+ mentions
SASqPCR (RRID:SCR_003056) software resource All-in-one computer program for robust and rapid analysis of quantitative reverse transcription real-time polymerase chain reaction (RT-qPCR) data in SAS. It incorporates all functions important for RT-qPCR data analysis including assessment of PCR efficiencies, validation of internal reference genes and normalizers, normalization of confounding variations across samples and statistical comparisons of target gene expression in parallel samples. The program is highly automatic in data analyses and result output. The input data have no limitations for the number of genes or cDNA samples. Users can simply change the macro variables to test various analytical strategies, optimize results and customize the analytical processes. The program is also extendable allowing advanced SAS users to develop particular statistical tests appropriate for their experimental designs. Thus users are the actual decision-makers controlling RT-qPCR data analyses. The program has to be used in SAS software; however, extensive SAS programming knowledge is not required. standalone software, computation, analysis, statistics, rt-qpcr, cdna, mrna, gene expression, quantification, reference gene, normalization, sas is listed by: OMICtools
has parent organization: Google Code
PMID:22238653 New BSD License OMICS_02375 SCR_003056 SASqPCR: robust and rapid analysis of RT-qPCR data in SAS 2025-04-19 06:41:34 6
SurvComp
 
Resource Report
Resource Website
50+ mentions
SurvComp (RRID:SCR_003054) survcomp software resource R package providing functions to assess and to compare the performance of risk prediction (survival) models. differential expression, gene expression, visualization, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: Bioconductor
PMID:21903630 Artistic License, v2 OMICS_02373 SCR_003054 survcomp - Performance Assessment and Comparison for Survival Analysis 2025-04-19 06:41:34 52
ddCt
 
Resource Report
Resource Website
100+ mentions
ddCt (RRID:SCR_003396) ddCt software resource Software package providing an approximation method to determine relative gene expression with quantitative real-time PCR (qRT-PCR) experiments. It requires no standard curve for each primer-target pair, therefore reducing the working load and yet returning accurate enough results as long as the assumptions of the amplification efficiency hold. The package implements a pipeline to collect, analyze and visualize qRT-PCR results, for example those from TaqMan SDM software, mainly using the ddCt method. The pipeline can be either invoked by a script in command-line or through the API consisting of S4-Classes, methods and functions. differential expression, gene expression, microtitre plate assay, q-pcr is listed by: OMICtools
has parent organization: Bioconductor
GNU Lesser General Public License, v3 OMICS_02312 SCR_003396 Delta-Delta-Ct 2025-04-19 06:41:42 314
unifiedWMWqPCR
 
Resource Report
Resource Website
unifiedWMWqPCR (RRID:SCR_001706) software resource Software package that implements the unified Wilcoxon-Mann-Whitney Test for qPCR data. This modified test allows for testing differential expression in qPCR data. standalone software, mac os x, unix/linux, windows, r, gene expression, microtitre plate assay, qpcr, differential expression, multiple comparison, quality control, visualization, qpcr, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24794933 GNU General Public License, v2 or greater OMICS_03937, biotools:unifiedwmwqpcr https://bio.tools/unifiedwmwqpcr SCR_001706 unifiedWMWqPCR - Unified Wilcoxon-Mann Whitney Test for testing differential expression in qPCR data 2025-04-19 06:40:36 0
ExpressionPlot
 
Resource Report
Resource Website
1+ mentions
ExpressionPlot (RRID:SCR_001904) expressionplot software resource Software package consisting of a default back end, which prepares raw sequencing or Affymetrix microarray data, and a web-based front end, which offers a biologically centered interface to browse, visualize, and compare different data sets. analysis, rna-seq, microarray, gene expression, affymetrix, prototype is listed by: OMICtools PMID:21797991 OMICS_01939 SCR_001904 2025-04-19 06:40:44 9
massiR
 
Resource Report
Resource Website
massiR (RRID:SCR_001157) software resource Software that predicts the sex of samples in gene expression microarray datasets. standalone software, mac os x, unix/linux, windows, r, classification, clustering, gene expression, microarray, quality control, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24659105 GNU General Public License, v3 biotools:massir, OMICS_03638 https://bio.tools/massir SCR_001157 massiR: MicroArray Sample Sex Identifier, MicroArray Sample Sex Identifier 2025-04-19 06:40:22 0
yaqcaffy
 
Resource Report
Resource Website
1+ mentions
yaqcaffy (RRID:SCR_001295) yaqcaffy software resource Software package for quality control of Affymetrix GeneChip expression data and reproducibility analysis of human whole genome chips with the MAQC reference datasets. microarray, one channel, quality control, report writing, affymetrix, gene expression, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Artistic License, v2 BioTools:yaqcaffy, biotools:yaqcaffy, OMICS_02040 https://bio.tools/yaqcaffy
https://bio.tools/yaqcaffy
https://bio.tools/yaqcaffy
SCR_001295 yaqcaffy - Affymetrix expression data quality control and reproducibility analysis 2025-04-19 06:40:25 2
RCASPAR
 
Resource Report
Resource Website
RCASPAR (RRID:SCR_001253) RCASPAR software resource Software package for survival time prediction based on a piecewise baseline hazard Cox regression model. It is meant to help predict survival times in the presence of high-dimensional explanatory covariates. gene expression, genetics, proteomics, visualization, acgh is listed by: OMICtools
has parent organization: Bioconductor
GNU General Public License, v3 or newer OMICS_02087 SCR_001253 2025-04-19 06:40:24 0
sRAP
 
Resource Report
Resource Website
10+ mentions
sRAP (RRID:SCR_001297) sRAP software resource Software package that provides a pipeline for gene expression analysis (primarily for RNA-Seq data). The normalization function is specific for RNA-Seq analysis, but all other functions (Quality Control Figures, Differential Expression and Visualization, and Functional Enrichment via BD-Func) will work with any type of gene expression data. gene expression, differential expression, go, gene set enrichment, microarray, preprocessing, quality control, rna-seq, statistical method, visualization is listed by: OMICtools
has parent organization: Bioconductor
GNU General Public License, v3 OMICS_02038 SCR_001297 Simplified RNA-Seq Analysis 2025-04-19 06:40:25 15
SNM
 
Resource Report
Resource Website
1+ mentions
SNM (RRID:SCR_001299) SNM software resource Software package that uses a modeling strategy especially designed for normalizing high-throughput genomic data. The premise is that your data is a function of study-specific variables which are either biological variables that represent the target of the statistical analysis, or adjustment variables that represent factors arising from the experimental or biological setting the data is drawn from. The SNM approach aims to simultaneously model all study-specific variables in order to more accurately characterize the biological or clinical variables of interest. differential expression, exon array, gene expression, microarray, multi channel, multiple comparison, one channel, preprocessing, quality control, transcription, two channel is listed by: OMICtools
has parent organization: Bioconductor
GNU Lesser General Public License OMICS_02036 SCR_001299 Supervised Normalization of Microarrays 2025-04-19 06:40:25 1
waveTiling
 
Resource Report
Resource Website
waveTiling (RRID:SCR_001322) waveTiling software resource Software package to conduct transcriptome analysis for tiling arrays based on fast wavelet-based functional models. differential expression, microarray, gene expression, time course is listed by: OMICtools
has parent organization: Bioconductor
PMID:22974078 GNU General Public License, v2 or newer OMICS_02014 SCR_001322 waveTiling - Wavelet-Based Models for Tiling Array Transcriptome Analysis 2025-04-19 06:40:26 0
AffyExpress
 
Resource Report
Resource Website
1+ mentions
AffyExpress (RRID:SCR_001321) AffyExpress software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package for quality assessment and to identify differentially expressed genes in the Affymetrix gene expression data. differential expression, microarray, annotation, one channel, preprocessing, quality control, report writing, visualization, gene expression is listed by: OMICtools
has parent organization: Bioconductor
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02015 SCR_001321 AffyExpress - Affymetrix Quality Assessment and Analysis Tool 2025-04-19 06:40:26 2
DEXUS
 
Resource Report
Resource Website
1+ mentions
DEXUS (RRID:SCR_001309) DEXUS software resource Software package that identifies differentially expressed genes in RNA-Seq data under all possible study designs such as studies without replicates, without sample groups, and with unknown conditions. It works also for known conditions, for example for RNA-Seq data with two or multiple conditions. RNA-Seq read count data can be provided both by the S4 class Count Data Set and by read count matrices. Differentially expressed transcripts can be visualized by heatmaps, in which unknown conditions, replicates, and samples groups are also indicated. This software is fast since the core algorithm is written in C. For very large data sets, a parallel version of DEXUS is provided in this package. DEXUS is a statistical model that is selected in a Bayesian framework by an EM algorithm. It does not need replicates to detect differentially expressed transcripts, since the replicates (or conditions) are estimated by the EM method for each transcript. The method provides an informative/non-informative value to extract differentially expressed transcripts at a desired significance level or power. classification, differential expression, gene expression, hapmap, quality control, rna-seq, sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24049071 GNU Lesser General Public License, v2 or newer biotools:dexus, OMICS_02024 https://bio.tools/dexus SCR_001309 DEXUS - Identifying Differential Expression in RNA-Seq Studies with Unknown Conditions or without Replicates 2025-04-19 06:40:26 1

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