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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
tweeDEseq
 
Resource Report
Resource Website
1+ mentions
tweeDEseq (RRID:SCR_003038) software resource Software for differential expression analysis of RNA-seq using the Poisson-Tweedie family of distributions. standalone software, unix/linux, mac os x, windows, c, r, rna-seq, differential expression, sequencing, statistical method, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23965047 Free, Available for download, Freely available OMICS_02406, biotools:tweedeseq https://bio.tools/tweedeseq SCR_003038 SciCrunch Registry tweeDEseq: RNA-seq data analysis using the Poisson-Tweedie family of distributions 2026-10-31 12:13:16 4
BRAIN
 
Resource Report
Resource Website
10+ mentions
BRAIN (RRID:SCR_003018) software resource Software package for calculating aggregated isotopic distribution and exact center-masses for chemical substances (in this version composed of C, H, N, O and S). standalone software, mac os x, unix/linux, windows, r, mass spectrometry, proteomics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23350948 GNU General Public License, v2 biotools:brain, OMICS_02410 https://bio.tools/brain SCR_003018 SciCrunch Registry Baffling Recursive Algorithm for Isotopic distributioN calculations, Baffling Recursive Algorithm for Isotope distributioN 2026-10-31 12:13:17 47
SurvComp
 
Resource Report
Resource Website
50+ mentions
SurvComp (RRID:SCR_003054) survcomp software resource R package providing functions to assess and to compare the performance of risk prediction (survival) models. differential expression, gene expression, visualization, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: Bioconductor
PMID:21903630 Free, Available for download, Freely available OMICS_02373 SCR_003054 SciCrunch Registry survcomp - Performance Assessment and Comparison for Survival Analysis 2026-10-31 12:13:17 61
Piano
 
Resource Report
Resource Website
100+ mentions
Piano (RRID:SCR_003200) data analysis software, data processing software, software application, software resource Software R-package for running gene set analysis using various statistical methods, from different gene level statistics and a wide range of gene-set collections. The Piano package contains functions for combining the results of multiple runs of gene set analyses. r, omics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Chalmers University of Technology; Gothenburg; Sweden
has parent organization: Bioconductor
PMID:23444143 Free, Available for download, Freely available OMICS_01558, biotools:piano https://bio.tools/piano SCR_003200 SciCrunch Registry 2026-10-31 12:13:20 188
ddCt
 
Resource Report
Resource Website
100+ mentions
ddCt (RRID:SCR_003396) ddCt software resource Software package providing an approximation method to determine relative gene expression with quantitative real-time PCR (qRT-PCR) experiments. It requires no standard curve for each primer-target pair, therefore reducing the working load and yet returning accurate enough results as long as the assumptions of the amplification efficiency hold. The package implements a pipeline to collect, analyze and visualize qRT-PCR results, for example those from TaqMan SDM software, mainly using the ddCt method. The pipeline can be either invoked by a script in command-line or through the API consisting of S4-Classes, methods and functions. differential expression, gene expression, microtitre plate assay, q-pcr is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02312 SCR_003396 SciCrunch Registry Delta-Delta-Ct 2026-10-31 12:13:24 328
ggbio
 
Resource Report
Resource Website
10+ mentions
ggbio (RRID:SCR_003313) software resource An R package for extending the grammar of graphics for genomic data. The graphics are designed to answer common scientific questions, in particular those often asked of high throughput genomics data. All core Bioconductor data structures are supported, where appropriate. The package supports detailed views of particular genomic regions, as well as genome-wide overviews. Supported overviews include ideograms and grand linear views. High-level plots include sequence fragment length, edge-linked interval to data view, mismatch pileup, and several splicing summaries. standalone software, unix/linux, mac os x, windows, r, infrastructure, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:22937822 Free, Available for download, Freely available biotools:ggbio, OMICS_04660 http://www.tengfei.name/ggbio/, https://bio.tools/ggbio SCR_003313 SciCrunch Registry ggbio - Visualization tools for genomic data 2026-10-31 12:13:23 16
OmicCircos
 
Resource Report
Resource Website
50+ mentions
OmicCircos (RRID:SCR_003292) software resource An R software application and package used to generate high-quality circular plots for visualizing genomic variations, including mutation patterns, copy number variations (CNVs), expression patterns, and methylation patterns. standalone software, unix/linux, mac os x, windows, r, annotation, statistical method, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:24526832 Free, Available for download, Freely available OMICS_04659 http://www.bioconductor.org/packages/release/bioc/html/OmicCircos.html SCR_003292 SciCrunch Registry OmicCircos: High-quality circular visualization of omic data 2026-10-31 12:13:21 83
sRAP
 
Resource Report
Resource Website
10+ mentions
sRAP (RRID:SCR_001297) sRAP software resource Software package that provides a pipeline for gene expression analysis (primarily for RNA-Seq data). The normalization function is specific for RNA-Seq analysis, but all other functions (Quality Control Figures, Differential Expression and Visualization, and Functional Enrichment via BD-Func) will work with any type of gene expression data. gene expression, differential expression, go, gene set enrichment, microarray, preprocessing, quality control, rna-seq, statistical method, visualization is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02038 http://www.bioconductor.org/packages/release/bioc/html/sRAP.html SCR_001297 SciCrunch Registry Simplified RNA-Seq Analysis 2026-10-31 12:12:49 16
yaqcaffy
 
Resource Report
Resource Website
1+ mentions
yaqcaffy (RRID:SCR_001295) yaqcaffy software resource Software package for quality control of Affymetrix GeneChip expression data and reproducibility analysis of human whole genome chips with the MAQC reference datasets. microarray, one channel, quality control, report writing, affymetrix, gene expression, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available BioTools:yaqcaffy, biotools:yaqcaffy, OMICS_02040 http://www.bioconductor.org/packages/release/bioc/html/yaqcaffy.html SCR_001295 SciCrunch Registry yaqcaffy - Affymetrix expression data quality control and reproducibility analysis 2026-10-31 12:12:49 3
SNM
 
Resource Report
Resource Website
1+ mentions
SNM (RRID:SCR_001299) SNM software resource Software package that uses a modeling strategy especially designed for normalizing high-throughput genomic data. The premise is that your data is a function of study-specific variables which are either biological variables that represent the target of the statistical analysis, or adjustment variables that represent factors arising from the experimental or biological setting the data is drawn from. The SNM approach aims to simultaneously model all study-specific variables in order to more accurately characterize the biological or clinical variables of interest. differential expression, exon array, gene expression, microarray, multi channel, multiple comparison, one channel, preprocessing, quality control, transcription, two channel is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02036 SCR_001299 SciCrunch Registry Supervised Normalization of Microarrays 2026-10-31 12:12:49 1
ChIPsim
 
Resource Report
Resource Website
1+ mentions
ChIPsim (RRID:SCR_001293) ChIPsim software resource Software package providing a general framework for the simulation of ChIP-seq data. Although currently focused on nucleosome positioning the package is designed to support different types of experiments. chip-seq, infrastructure, simulation is listed by: OMICtools
has parent organization: Bioconductor
GNU General Public License, v2 or newer OMICS_02042 SCR_001293 SciCrunch Registry ChIPsim - Simulation of ChIP-seq experiments 2026-10-31 12:12:49 1
methyAnalysis
 
Resource Report
Resource Website
1+ mentions
methyAnalysis (RRID:SCR_001290) methyAnalysis software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package for DNA methylation data analysis and visualization. A new class is defined to keep the chromosome location information together with the data. The current version of the package mainly focuses on analyzing the Illumina Infinium methylation array data, but most methods can be generalized to other methylation array or sequencing data. dna methylation, microarray, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:21159174 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02046 SCR_001290 SciCrunch Registry methyAnalysis - DNA methylation data analysis and visualization 2026-10-31 12:12:49 9
les
 
Resource Report
Resource Website
les (RRID:SCR_001291) les software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package that estimates Loci of Enhanced Significance (LES) in tiling microarray data. These are regions of regulation such as found in differential transcription, CHiP-chip, or DNA modification analysis. The package provides a universal framework suitable for identifying differential effects in tiling microarray data sets, and is independent of the underlying statistics at the level of single probes. loci of enhanced significance, tiling microarray, tiling, microarray, chip-chip, dna modification, probe, dna methylation, differential expression, microarray, transcription, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
THIS RESOURCE IS NO LONGER IN SERVICE biotools:les, OMICS_02045 https://bioconductor.org/packages/les/, https://bio.tools/les SCR_001291 SciCrunch Registry les package: Identifying Differential Effects in Tiling Microarray Data, Loci of Enhanced Significance 2026-10-31 12:12:49 0
beadarraySNP
 
Resource Report
Resource Website
beadarraySNP (RRID:SCR_001281) beadarraySNP software resource Software package for importing data from Illumina SNP experiments and performing copy number calculations and reports. copy number variation, data import, genetic variability, preprocessing, snp, two channel is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02056 http://www.bioconductor.org/packages/devel/bioc/html/beadarraySNP.html SCR_001281 SciCrunch Registry beadarraySNP - Normalization and reporting of Illumina SNP bead arrays 2026-10-31 12:12:48 0
RCASPAR
 
Resource Report
Resource Website
RCASPAR (RRID:SCR_001253) RCASPAR software resource Software package for survival time prediction based on a piecewise baseline hazard Cox regression model. It is meant to help predict survival times in the presence of high-dimensional explanatory covariates. gene expression, genetics, proteomics, visualization, acgh is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02087 SCR_001253 SciCrunch Registry 2026-10-31 12:12:48 0
CNVtools
 
Resource Report
Resource Website
10+ mentions
CNVtools (RRID:SCR_001250) CNVtools software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Software package to facilitate the testing of Copy Number Variant data for genetic association, typically in case-control studies. genetic variability, copy number variant, genetic association is listed by: OMICtools
has parent organization: Bioconductor
PMID:18776912 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02090 SCR_001250 SciCrunch Registry CNVtools - A package to test genetic association with CNV data 2026-10-31 12:12:48 12
CGEN
 
Resource Report
Resource Website
10+ mentions
CGEN (RRID:SCR_001251) CGEN data analysis software, data processing software, software application, software resource Software R package for analysis of case-control studies in genetic epidemiology. genetic, epidemiology, r, case-control, clustering, multiple comparison, snp is listed by: OMICtools
has parent organization: Bioconductor
PMID:21387464 Free, Available for download, Freely available OMICS_02089 SCR_001251 SciCrunch Registry CGEN - An R package for analysis of case-control studies in genetic epidemiology 2026-10-31 12:12:48 18
multtest
 
Resource Report
Resource Website
10+ mentions
multtest (RRID:SCR_001255) multtest software resource Software package for non-parametric bootstrap and permutation resampling-based multiple testing procedures (including empirical Bayes methods) for controlling the family-wise error rate (FWER), generalized family-wise error rate (gFWER), tail probability of the proportion of false positives (TPPFP), and false discovery rate (FDR). Several choices of bootstrap-based null distribution are implemented (centered, centered and scaled, quantile-transformed). Single-step and step-wise methods are available. Tests based on a variety of t- and F-statistics (including t-statistics based on regression parameters from linear and survival models as well as those based on correlation parameters) are included. When probing hypotheses with t-statistics, users may also select a potentially faster null distribution which is multivariate normal with mean zero and variance covariance matrix derived from the vector influence function. Results are reported in terms of adjusted p-values, confidence regions and test statistic cutoffs. The procedures are directly applicable to identifying differentially expressed genes in DNA microarray experiments. differential expression, microarray, multiple comparison, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available biotools:multtest, OMICS_02085 https://bio.tools/multtest SCR_001255 SciCrunch Registry multtest - Resampling-based multiple hypothesis testing 2026-10-31 12:12:48 37
ITALICS
 
Resource Report
Resource Website
ITALICS (RRID:SCR_001274) ITALICS software resource Software package to normalize of Affymetrix GeneChip Human Mapping 100K and 500K set. affymetrix, copy number variation, microarray is listed by: OMICtools
has parent organization: Bioconductor
PMID:18252739 Free, Available for download, Freely available OMICS_02064 SCR_001274 SciCrunch Registry 2026-10-31 12:12:48 0
GenoSet
 
Resource Report
Resource Website
GenoSet (RRID:SCR_001275) GenoSet data analysis software, data processing software, software application, software resource Software package to load, manipulate, and plot copynumber and BAF data by providing classes similar to ExpressionSet for copy number analysis. The class extends ExpressionSet by adding a locData slot for a RangedData or GRanegs object. This object contains feature genome location data and provides for efficient subsetting on genome location. CNSet and BAFSet extend GenoSet and require assayData matrices for Copy Number (cn) or Log-R Ratio (lrr) and B-Allele Frequency (baf) data. Implements and provides convenience functions for processing of copy number and B-Allele Frequency data. copy number variation, data representation, infrastructure, microarray, snp is listed by: OMICtools
has parent organization: Bioconductor
Artistic License, v2 OMICS_02063 SCR_001275 SciCrunch Registry genoset - Provides classes similar to ExpressionSet for copy number analysis 2026-10-31 12:12:48 0

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