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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
casper Resource Report Resource Website 100+ mentions |
casper (RRID:SCR_006613) | casper | software resource | Software to infer alternative splicing from paired-end RNA-seq data. The model is based on counting paths across exons, rather than pairwise exon connections, and estimates the fragment size and start distributions non-parametrically, which improves estimation precision. | bio.tools |
is listed by: OMICtools is listed by: Debian is listed by: bio.tools has parent organization: Bioconductor |
GNU General Public License, v2 or greater | biotools:casper, OMICS_01270 | https://bio.tools/casper | SCR_006613 | casper - Characterization of Alternative Splicing based on Paired-End Reads, Characterization of Alternative Splicing based on Paired-End Reads | 2025-02-14 10:31:31 | 129 | ||||||
|
SpliceTrap Resource Report Resource Website 10+ mentions |
SpliceTrap (RRID:SCR_006728) | SpliceTrap | software resource | A statistic tool for quantifying exon inclusion ratios in paired-end RNA-seq data, with broad applications for the study of alternative splicing. SpliceTrap approaches to exon inclusion level estimation as a Bayesian inference problem. For every exon it quantifies the extent to which it is included, skipped or subjected to size variations due to alternative 3?/5? splice sites or Intron Retention. In addition, SpliceTrap can quantify alternative splicing within a single cellular condition, with no need of a background set of reads. | bio.tools |
is listed by: OMICtools is listed by: Debian is listed by: bio.tools is related to: Galaxy has parent organization: Cold Spring Harbor Laboratory |
PMID:21896509 | biotools:splicetrap, OMICS_01292 | https://bio.tools/splicetrap | SCR_006728 | 2025-02-14 10:30:53 | 16 | |||||||
|
BEDTools Resource Report Resource Website 5000+ mentions |
BEDTools (RRID:SCR_006646) | BEDTools | software resource | A powerful toolset for genome arithmetic allowing one to address common genomics tasks such as finding feature overlaps and computing coverage. Bedtools allows one to intersect, merge, count, complement, and shuffle genomic intervals from multiple files in widely-used genomic file formats such as BAM, BED, GFF/GTF, VCF. While each individual tool is designed to do a relatively simple task (e.g., intersect two interval files), quite sophisticated analyses can be conducted by combining multiple bedtools operations on the UNIX command line. | genomics, bed, sam, bam, overlap, sequencing, intersect, coverage, gff, vcf, bedgraph, interval, genome arithmetic, bio.tools |
is listed by: OMICtools is listed by: Debian is listed by: bio.tools is listed by: SoftCite is related to: Hydra is related to: pybedtools is required by: SL-quant |
PMID:20110278 DOI:10.1093/bioinformatics/btq033 |
GNU General Public License, v2, Acknowledgement requested | OMICS_01159, biotools:bedtools | https://code.google.com/p/bedtools/ https://bio.tools/bedtools https://sources.debian.org/src/bedtools/ |
SCR_006646 | bedtools - a swiss army knife for genome arithmetic, bedtools: a flexible suite of utilities for comparing genomic features | 2025-02-14 10:30:51 | 8670 | |||||
|
ALEXA-Seq Resource Report Resource Website 1+ mentions |
ALEXA-Seq (RRID:SCR_006700) | ALEXA-Seq | software resource | A method for using massively parallel paired-end transcriptome sequencing for ''alternative expression analysis''. | is listed by: OMICtools | OMICS_01328 | SCR_006700 | 2025-02-14 10:30:56 | 6 | ||||||||||
|
SpliceGrapher Resource Report Resource Website 10+ mentions |
SpliceGrapher (RRID:SCR_006657) | SpliceGrapher | software resource | Software that predicts alternative splicing patterns and produces splice graphs that capture in a single structure the ways a gene''s exons may be assembled. It enhances gene models using evidence from next-generation sequencing and EST alignments. |
is listed by: OMICtools has parent organization: SourceForge |
PMID:22293517 | OMICS_01266 | SCR_006657 | 2025-02-14 10:30:55 | 21 | |||||||||
|
ChIPXpress Resource Report Resource Website 1+ mentions |
ChIPXpress (RRID:SCR_006653) | ChIPXpress | software resource | A R package designed to improve ChIP-seq and ChIP-chip target gene ranking using publicly available gene expression data. It takes as input predicted transcription factor (TF) bound genes from ChIPx data and uses a corresponding database of gene expression profiles downloaded from NCBI GEO to rank the TF bound targets in order of which gene is most likely to be functional TF target. | gene expression, chip-seq, chip-chip, transcription factor, target gene, gene, gene expression profile |
is listed by: OMICtools is related to: Gene Expression Omnibus has parent organization: Bioconductor |
GNU General Public License, v2 or greater | OMICS_00516 | SCR_006653 | ChIPXpress: enhanced transcription factor target gene identification from ChIP-seq and ChIP-chip data using publicly available gene expression profiles | 2025-02-14 10:30:55 | 2 | |||||||
|
SoftSearch Resource Report Resource Website 1+ mentions |
SoftSearch (RRID:SCR_006683) | SoftSearch | software resource | A sensitive structural variant (SV) detection software tool for Illumina paired-end next-generation sequencing data. It simultaneously utilizes soft-clipping and read-pair strategies for detecting SVs to increase sensitivity. Soft clips are proxies for split-reads that indicate part of the read maps to the reference genome, but the other part is not localized at the same place (e.g. breakpoint spanning reads). Discordant read-pairs refer to a read and its mate, where the insert size is greater (or less than) the expected distribution of the dataset ? or ? where the mapping orientation of the reads is unexpected (e.g. both on the same strand). SoftSearch looks for areas with soft-clipping in the genome that have discordant read pairs supporting the anomaly. Once areas with both these conditions are identified, the read and mate information is extracted directly from the BAM file containing the discordant reads, obviating the need for time-consuming and error-prone complex alignment strategies. Only a small number of soft-masked bases discordant read-pairs are necessary to identify an SV, which on their own would not be sufficient to make an SV call, thus highlighting SoftSearch?s improved sensitivity. SoftSearch is well suited to be ?plugged in? to most sequence analysis workflows, since it requires standard file inputs, such as a BAM file using almost any aligner and a reference genome FASTA file. Because SoftSearch requires soft-masked bases, the only requirement is that the aligner must have this functionality, which is usually turned on by default by many standard aligners (e.g. BWA, Novoalign, etc). | illumina, structural variant, next-generation sequencing, perl, academic |
is listed by: OMICtools has parent organization: Google Code |
GNU General Public License, v2 | OMICS_00322 | SCR_006683 | SoftSearch - Detecting Structural Variations Using Split Reads and Discordant Read Pairs | 2025-02-14 10:30:55 | 5 | |||||||
|
EDASeq Resource Report Resource Website 100+ mentions |
EDASeq (RRID:SCR_006751) | EDASeq | software resource | Software for numerical and graphical summaries of RNA-Seq read data. Within-lane normalization procedures to adjust for GC-content effect (or other gene-level effects) on read counts: loess robust local regression, global-scaling, and full-quantile normalization (Risso et al., 2011). Between-lane normalization procedures to adjust for distributional differences between lanes (e.g., sequencing depth): global-scaling and full-quantile normalization (Bullard et al., 2010). | data analysis, normalization, rna-seq |
is listed by: OMICtools has parent organization: Bioconductor has parent organization: National Cancer Institute |
OMICS_01231 | SCR_006751 | EDASeq: Exploratory Data Analysis and Normalization for RNA-Seq data | 2025-02-14 10:31:33 | 235 | ||||||||
|
mubiomics Resource Report Resource Website 1+ mentions |
mubiomics (RRID:SCR_006785) | mubiomics | software resource | A set of scripts (mostly python) for processing reads generated by the Roche 454 or Illumina next-gen sequencing platforms. Included are quality control, read demultiplexing and microbiome characterisation scripts for use with usearch, pplacer and RDP classifier. |
is listed by: OMICtools has parent organization: SourceForge |
OMICS_01059 | SCR_006785 | mubiomics - Scripts for processing next-gen sequencing data | 2025-02-14 10:30:58 | 3 | |||||||||
|
ShortRead Resource Report Resource Website 100+ mentions |
ShortRead (RRID:SCR_006813) | ShortRead | software resource | Software package for input, quality assessment and exploration of high-throughput sequence data. Used for input, quality assurance, and basic manipulation of `short read'' DNA sequences such as those produced by Solexa, 454, and related technologies, including exible import of common short read data formats. | high throughput sequence data, short read, DNA sequences, short read data |
is listed by: OMICtools is listed by: Debian is listed by: SoftCite has parent organization: Bioconductor |
PMID:19654119 | Free, Available for download, Freely available | OMICS_01076 | https://sources.debian.org/src/r-bioc-shortread/ | SCR_006813 | ShortRead - Classes and methods for high-throughput short-read sequencing data. | 2025-02-14 10:30:55 | 208 | |||||
|
mutationSeq Resource Report Resource Website 10+ mentions |
mutationSeq (RRID:SCR_006815) | mutationSeq | software resource | A software suite using feature-based classifiers for somatic mutation prediction from paired tumour/normal next-generation sequencing data. mutationSeq has the advantages of integrating different features (e.g., base qualities, mapping qualities, strand bias, and tailed distance features), and validated somatic mutations to make predictions. Given paired normal/tumour bam files, mutationSeq will output the probability of each candidate site being somatic. | next-generation sequencing, somatic mutation, tumor, normal |
is listed by: OMICtools is related to: JointSNVMix has parent organization: BC Cancer Agency |
Tumor, Normal | PMID:22084253 | OMICS_00086 | SCR_006815 | 2025-02-14 10:30:58 | 24 | |||||||
|
RIPSeeker Resource Report Resource Website 1+ mentions |
RIPSeeker (RRID:SCR_006810) | RIPSeeker | software resource | A statistical software package for identifying protein-associated transcripts from RIP-seq experiments. Infer and discriminate RIP peaks from RIP-seq alignments using two-state HMM with negative binomial emission probability. While RIPSeeker is specifically tailored for RIP-seq data analysis, it also provides a suite of bioinformatics tools integrated within this self-contained software package comprehensively addressing issues ranging from post-alignments processing to visualization and annotation. | rip-seq |
is listed by: OMICtools has parent organization: Bioconductor |
GNU General Public License, v2 | OMICS_00569 | SCR_006810 | RIPSeeker: a statistical package for identifying protein-associated transcripts from RIP-seq experiments | 2025-02-14 10:31:34 | 8 | |||||||
|
Qudaich Resource Report Resource Website |
Qudaich (RRID:SCR_006775) | Qudaich | software resource | A software package for local sequence alignment for next-generation sequencing (NGS) data. It generates the pairwise local alignments between a query dataset against a database. The main design purpose of qudaich is to focus on datasets from next generation sequencing. These the datasets generally have hundreds of thousand sequences or more, and so, the input database should contain large number of sequences. Qudaich is flexible and its algorithmic structure imposes no restriction on the absolute limit of the acceptable read length, but the current version of qudaich allow read length <2000 bp. Qudaich can be used to align DNA, translated DNA and protein sequences. | next-generation sequencing, alignment |
is listed by: OMICtools has parent organization: SourceForge |
OMICS_00678 | SCR_006775 | Queries and unique database alignment inferred by clustering homologs | 2025-02-14 10:30:57 | 0 | ||||||||
|
GBS barcode splitter Resource Report Resource Website |
GBS barcode splitter (RRID:SCR_006799) | GBS barcode splitter | software resource | PERL script used to split barcode of Illumina sequencing data created by GBS protocol (www.maizegenetics.net). The barcode has variable size. Paired-end reads are supported. | illumina |
is listed by: OMICtools has parent organization: SourceForge |
Free | OMICS_01050 | SCR_006799 | GBS barcode splitter - PERL script for split GBS reads by barcode | 2025-02-14 10:31:34 | 0 | |||||||
|
EBCall Resource Report Resource Website 10+ mentions |
EBCall (RRID:SCR_006791) | EBCall | software resource | A software package for somatic mutation detection (including InDels). EBCall uses not only paired tumor/normal sequence data of a target sample, but also multiple non-paired normal reference samples for evaluating distribution of sequencing errors, which leads to an accurate mutaiton detection even in case of low sequencing depths and low allele frequencies. | mutation, cancer, genome, sequencing, bio.tools |
is listed by: OMICtools is listed by: bio.tools is listed by: Debian has parent organization: University of Tokyo; Tokyo; Japan |
PMID:23471004 | Copyright conditions, Acknowledgement required | biotools:ebcall, OMICS_00084 | https://bio.tools/ebcall | SCR_006791 | EBCall (Empirical Baysian mutation Calling), Empirical Baysian mutation Calling | 2025-02-14 10:30:58 | 18 | |||||
|
BAMStats Resource Report Resource Website 1+ mentions |
BAMStats (RRID:SCR_006973) | BAMStats | software resource | A GUI desktop tool for calculating and displaying metrics to assess the success of Next Generation Sequencing mapping tools. BAMstats is written in Java and based around the Picard API. | matlab, next generation sequencing, java |
is listed by: OMICtools has parent organization: SourceForge |
GNU General Public License | OMICS_01034 | SCR_006973 | 2025-02-14 10:30:58 | 8 | ||||||||
|
RamiGO Resource Report Resource Website 10+ mentions |
RamiGO (RRID:SCR_006922) | RamiGO | software resource | Software package with an R interface sending requests to AmiGO visualize, retrieving DAG GO trees, parsing GraphViz DOT format files and exporting GML files for Cytoscape. Also uses RCytoscape to interactively display AmiGO trees in Cytoscape. | visualization, analysis, ontology or annotation search engine, ontology or annotation visualization, other analysis, classification, go, graph, network, third party client, windows, mac os x, linux, unix, bio.tools |
is listed by: Gene Ontology Tools is listed by: OMICtools is listed by: Debian is listed by: bio.tools is related to: Gene Ontology is related to: Cytoscape is related to: AmiGO has parent organization: Dana-Farber Cancer Institute has parent organization: Bioconductor |
PMID:23297033 | Artistic License, v2 | biotools:ramigo, OMICS_02267, nlx_149331 | http://bioconductor.org/packages/release/bioc/html/RamiGO.html https://bio.tools/ramigo |
SCR_006922 | ramigo, RamiGO - AmiGO visualize R interface | 2025-02-14 10:30:57 | 11 | |||||
|
RazerS Resource Report Resource Website 10+ mentions |
RazerS (RRID:SCR_006889) | RazerS | software resource | A read mapping software program with adjustable sensitivity based on counting q-grams. RazerS 3 supports shared-memory parallelism, an additional seed-based filter with adjustable sensitivity, a much faster, banded version of the Myers? bit-vector algorithm for verification, memory saving measures and support for the SAM output format. This leads to a much improved performance for mapping reads, in particular long reads with many errors. | next-generation sequencing, c++, openmp, linux, mac os x, windows |
is listed by: OMICtools has parent organization: Free University of Berlin; Berlin; Germany |
PMID:22923295 PMID:19592482 |
GNU General Public License | OMICS_00679 | SCR_006889 | 2025-02-14 10:30:57 | 12 | |||||||
|
ArtificialFastqGenerator Resource Report Resource Website 10+ mentions |
ArtificialFastqGenerator (RRID:SCR_006880) | ArtificialFastqGenerator | software resource | Software to evaluate and improve the accuracy of sequencing error under different experimental conditions. It can identify which components of a system may be suboptimal and which regions of the genome may be problematic. | matlab, java, Next Generation Sequencing, aligns reads, reference genome |
is listed by: OMICtools is listed by: Debian |
PMID:23152858 | GNU GPL v3 | OMICS_00248, SCR_015979 | https://sources.debian.org/src/artfastqgenerator/ | SCR_006880 | Artfastqgenerator - Ouputs artificial FASTQ files derived from a reference genome | 2025-02-14 10:30:56 | 10 | |||||
|
BarraCUDA Resource Report Resource Website 1+ mentions |
BarraCUDA (RRID:SCR_006881) | BarraCUDA | software resource | A sequence mapping software that utilizes the massive parallelism of graphics processing units to accelerate the inexact alignment of short sequence reads to a particular location on a reference genome. It can align a paired-end library containing 14 million pairs of 76bp reads to the Human genome in about 27 minutes (from fastq files to SAM alignment) using a ��380 NVIDIA Geforce GTX 680*. The alignment throughput can be boosted further by using multiple GPUs (up to 8) at the same time. Being based on BWA (http://bio-bwa.sf.net) from the Sanger Institute, BarraCUDA delivers a high level of alignment fidelity and is comparable to other mainstream alignment programs. It can perform gapped alignment with gap extensions, in order to minimise the number of false variant calls in re-sequencing studies. | gpu/cuda, bio.tools |
is listed by: OMICtools is listed by: bio.tools is listed by: Debian has parent organization: University of Cambridge; Cambridge; United Kingdom has parent organization: SourceForge |
PMID:22244497 PMID:19451168 |
Acknowledgement requested | OMICS_00650, biotools:barracuda | https://bio.tools/barracuda | SCR_006881 | 2025-02-14 10:31:00 | 4 |
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