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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00007178
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00006580(tlp-1)
Genomic Alteration: WBGene00001864(him-5), WBGene00006580(tlp-1)
Availability: available
Source References: PMID:32078235
Synonyms: tlp-1(bx85) IV; him-5(e1490) V.
Alternate IDs: WB-STRAIN:EM347, CGC_EM347
Notes: Although hermaphrodites appear WT in other ways, there are some problems with T cell lineages (affecting the phasmids) and tail cell fusions. Variably Dyf. Male tail tip morphogenesis is also defective, resulting in blobby, leptoderan tails. Males are infertile due to an inability to properly copulate. tlp-1 encodes a nuclear protein with a single C2H2-type zinc finger domain and an N-terminal SPLALLA domain, similar to that of Sp1 transcription factors of vertebrates. The bx85 mutation involves a truncation of TLP-1 due to a frameshift caused by a 5-bp deletion.
Proper citation: RRID:WB-STRAIN:WBStrain00007178 Copy
http://www.wormbase.org/db/get?name=WBStrain00007175
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00003111(mab-20)
Genomic Alteration: WBGene00001864(him-5), WBGene00003111(mab-20)
Availability: available
Source References: PMID:1782863
Synonyms: mab-20(bx61) I; him-5(e1490) V.
Alternate IDs: WB-STRAIN:EM253, CGC_EM253
Notes: Ray 3 and 4 fusion >60% at non-permissive temp. Ray 1 and 2 fusion about 10% at non-permissive temp. ts period is around L3-L4.
Proper citation: RRID:WB-STRAIN:WBStrain00007175 Copy
http://www.wormbase.org/db/get?name=WBStrain00007174
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00006543(tbx-2)
Genomic Alteration: WBGene00001864(him-5), WBGene00006543(tbx-2)
Availability: available
Synonyms: tbx-2(bx59) III; him-5(e1490) V.
Alternate IDs: WB-STRAIN:EM207, CGC_EM207
Notes: Conditional lethal: inviable when grown at 25C. Wild type at 16C. Viable when grown at 20C; partial ray loss at 20C. Shifting males during ray assembly to non-permissive temperature results in ray loss. No lineage defect.
Proper citation: RRID:WB-STRAIN:WBStrain00007174 Copy
http://www.wormbase.org/db/get?name=WBStrain00007171
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00001864(him-5)|WBGene00004300(ram-2)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00001864(him-5), WBGene00004300(ram-2)
Availability: available
Synonyms: dpy-10(e128) ram-2(bx39) II; him-5(e1490) V.
Alternate IDs: WB-STRAIN:EM146, CGC_EM146
Notes: Dpy. Abnormal rays.|"Made_by: Baird S"
Proper citation: RRID:WB-STRAIN:WBStrain00007171 Copy
http://www.wormbase.org/db/get?name=WBStrain00007103
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)
Genomic Alteration: WBGene00001864(him-5)
Availability: available
Synonyms: oxSi255 I; oxTi81 him-5(e1490) V.
Alternate IDs: WB-STRAIN:EG8961, CGC_EG8961
Notes: oxSi255 [snt-1p::GFP + Cbr-unc-119(+)] I. Integration into ttTi4348 mosSCI site (I:-5.32). Pan-neuronal GFP expression visible under dissection microscope. oxTi81 [eft-3p::GFP::H2B::tbb-2 3'UTR + unc-18(+)] V. Nuclear, green fluorescence is broadly expressed (in most cells). Integration into chr.V: 1.21. Him. Combined fluorescent balancer strain for LG I and LG IV. Strain contains him-5(e1490) to generate males for crosses.
Proper citation: RRID:WB-STRAIN:WBStrain00007103 Copy
http://www.wormbase.org/db/get?name=WBStrain00007189
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00044992(rax-2)
Genomic Alteration: WBGene00001864(him-5), WBGene00044992(rax-2)
Availability: available
Synonyms: rax-2(bx131) III; bxIs14 him-5(e1490) V.
Alternate IDs: WB-STRAIN:EM886, CGC_EM886
Notes: bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
Proper citation: RRID:WB-STRAIN:WBStrain00007189 Copy
http://www.wormbase.org/db/get?name=WBStrain00007188
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00004945(sop-2)
Genomic Alteration: WBGene00001864(him-5), WBGene00004945(sop-2)
Availability: available
Synonyms: sop-2(bx91) II; him-5(e1490) V.
Alternate IDs: WB-STRAIN:EM723, CGC_EM723
Notes: Made_by: H. Zhang/S. Emmons|"Temperature sensitive. Early larval arrest at 25C. At 20C, Lon, PVul, Muv, Mog, ectopic Hox gene expression."
Proper citation: RRID:WB-STRAIN:WBStrain00007188 Copy
http://www.wormbase.org/db/get?name=WBStrain00007183
Source Database: WormBase (WB)
Affected Genes: WBGene00001081(dpy-22)|WBGene00001864(him-5)|WBGene00003912(pal-1)
Genomic Alteration: WBGene00001081(dpy-22), WBGene00001864(him-5), WBGene00003912(pal-1)
Availability: available
Synonyms: pal-1(e2091) III; him-5(e1490) V; dpy-22(bx103) X.
Alternate IDs: WB-STRAIN:EM507, CGC_EM507
Notes: V6 produces rays instead of alae in pal-1; sop-1 mutants. No obvious phenotype in a pal-1(+) background. Previously called sop-1(bx103).
Proper citation: RRID:WB-STRAIN:WBStrain00007183 Copy
http://www.wormbase.org/db/get?name=WBStrain00007182
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00001949(hlh-2)|WBGene00003018(lin-32)
Genomic Alteration: WBGene00001864(him-5), WBGene00001949(hlh-2), WBGene00003018(lin-32)
Availability: available
Synonyms: hlh-2(bx108) I; him-5(e1490) V; lin-32(e1926) X.
Alternate IDs: WB-STRAIN:EM496, CGC_EM496
Notes: Males are rayless. hlh-2(bx108) strongly and semi-dominantly enhances the ray-loss phenotype of lin-32(e1926).
Proper citation: RRID:WB-STRAIN:WBStrain00007182 Copy
http://www.wormbase.org/db/get?name=WBStrain00007181
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00003912(pal-1)|WBGene00004946(sop-3)
Genomic Alteration: WBGene00001864(him-5), WBGene00003912(pal-1), WBGene00004946(sop-3)
Availability: available
Synonyms: sop-3(bx96) I; pal-1(e2091) III; him-5(e1490) V.
Alternate IDs: WB-STRAIN:EM493, CGC_EM493
Notes: V6 produces rays instead of alae in sop-3; pal-1 mutants.
Proper citation: RRID:WB-STRAIN:WBStrain00007181 Copy
http://www.wormbase.org/db/get?name=WBStrain00007114
Source Database: WormBase (WB)
Affected Genes: WBGene00004042(plk-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004042(plk-1), WBGene00006843(unc-119)
Availability: available
Synonyms: egxSi100 II; plk-1(egx3[C52V, L115G]); unc-119(ed3) III.
Alternate IDs: WB-STRAIN:EGD334, CGC_EGD334
Notes: egxSi100 [mex-5p::GFP::pos-1 + unc-119(+)] II. Single-copy transgene expressing GFP::POS-1. Reference: Han et al, Current Biology 2017.
Proper citation: RRID:WB-STRAIN:WBStrain00007114 Copy
http://www.wormbase.org/db/get?name=WBStrain00007113
Source Database: WormBase (WB)
Affected Genes: WBGene00003230(mex-5)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00003230(mex-5), WBGene00006843(unc-119)
Availability: available
Synonyms: egxSi100 II; unc-119(ed3) III; mex-5(egx2[T186A]) IV.
Alternate IDs: WB-STRAIN:EGD282, CGC_EGD282
Notes: egxSi100 [mex-5p::GFP::pos-1 + unc-119(+)] II. Single-copy transgene expressing GFP::POS-1 forms a weaker gradient in the cytoplasm of the one-cell zygote than in wild-type. Reference: Han et al, Current Biology 2017.
Proper citation: RRID:WB-STRAIN:WBStrain00007113 Copy
http://www.wormbase.org/db/get?name=WBStrain00007110
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: egxSi109 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:EGD271, CGC_EGD271
Notes: egxSi109 [mex-5p::GFP::pos-1(S199A, S210A, S216A, S237A & T242A) + unc-119(+)] II. Single-copy transgene expressing mutated POS-1 with GFP tag. GFP::POS-1 is uniformly distributed in the cytoplasm of the one-cell zygote. Reference: Han et al, Current Biology 2017.
Proper citation: RRID:WB-STRAIN:WBStrain00007110 Copy
http://www.wormbase.org/db/get?name=WBStrain00007197
Source Database: WormBase (WB)
Affected Genes: WBGene00013672(catp-1)
Genomic Alteration: WBGene00013672(catp-1)
Availability: available
Source References: PMID:32292107
Synonyms: catp-1(kr17) I.
Alternate IDs: WB-STRAIN:EN17, CGC_EN17
Notes: DMPP resistant. Mos1 insertion.|"WBStrain provided so WBPaper00059550 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00007197 Copy
http://www.wormbase.org/db/get?name=WBStrain00007193
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00045079(rax-3)
Genomic Alteration: WBGene00001864(him-5), WBGene00045079(rax-3)
Availability: available
Synonyms: rax-3(bx138) I; bxIs14 him-5(e1490) V.
Alternate IDs: WB-STRAIN:EM908, CGC_EM908
Notes: bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
Proper citation: RRID:WB-STRAIN:WBStrain00007193 Copy
http://www.wormbase.org/db/get?name=WBStrain00007192
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00045079(rax-3)
Genomic Alteration: WBGene00001864(him-5), WBGene00045079(rax-3)
Availability: available
Synonyms: rax-3(bx133) I; bxIs14 him-5(e1490) V.
Alternate IDs: WB-STRAIN:EM907, CGC_EM907
Notes: bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
Proper citation: RRID:WB-STRAIN:WBStrain00007192 Copy
http://www.wormbase.org/db/get?name=WBStrain00007190
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00016539(madd-2)
Genomic Alteration: WBGene00001864(him-5), WBGene00016539(madd-2)
Availability: available
Synonyms: madd-2(bx132) bxIs14 him-5(e1490) V.
Alternate IDs: WB-STRAIN:EM902, CGC_EM902
Notes: bxIs14 [pkd-2::GFP + pdx-1]. Ray axon defective.
Proper citation: RRID:WB-STRAIN:WBStrain00007190 Copy
http://www.wormbase.org/db/get?name=WBStrain00007109
Source Database: WormBase (WB)
Affected Genes: WBGene00003230(mex-5)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00003230(mex-5), WBGene00006843(unc-119)
Availability: available
Synonyms: egxSi100 II; unc-119(ed3) III; mex-5(egx1[F294N & F339N]) IV.
Alternate IDs: WB-STRAIN:EGD263, CGC_EGD263
Notes: egxSi100 [mex-5p::GFP::pos-1 + unc-119(+)] II. Single-copy transgene expressing GFP::POS-1. mex-5(egx1[F294N, F339N]) modifies the endogenous mex-5 locus to disrupt zinc finger motifs. Reference: Han et al, Current Biology 2017.
Proper citation: RRID:WB-STRAIN:WBStrain00007109 Copy
http://www.wormbase.org/db/get?name=WBStrain00007107
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: egxSi100 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:EGD224, CGC_EGD224
Notes: egxSi100 [mex-5p::GFP::pos-1 + unc-119(+)] II. Single-copy transgene expressing GFP::POS-1. Reference: Han et al, Current Biology 2017.
Proper citation: RRID:WB-STRAIN:WBStrain00007107 Copy
http://www.wormbase.org/db/get?name=WBStrain00007105
Source Database: WormBase (WB)
Affected Genes: WBGene00003230(mex-5)|WBGene00004027(pie-1)
Genomic Alteration: WBGene00003230(mex-5), WBGene00004027(pie-1)
Availability: available
Synonyms: pie-1(ne4301[pie-1::gfp]) III; mex-5(egx1[F294N & F339N]) IV.
Alternate IDs: WB-STRAIN:EGD175, CGC_EGD175
Notes: pie-1(ne4301) inserted GFP into pie-1 locus tagging endogenous pie-1 with GFP. mex-5(egx1[F294N, F339N]) modifies the endogenous mex-5 locus to disrupt zinc finger motifs. Reference: Han et al, Current Biology 2017.|"pie-1(ne4301) inserted GFP to pie-1 locus tagging endogenous pie-1 with GFP. mex-5(egx1[F294N, F339N]) modifies the endogenous mex-5 locus to disrupt zinc finger motifs. Reference: Han et al, Current Biology 2017."
Proper citation: RRID:WB-STRAIN:WBStrain00007105 Copy
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