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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

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  • Species:tetrahymena thermophila (facet)

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Organism Name Proper Citation Species Synonyms Notes Phenotype Affected Gene Genomic Alteration Catalog Number Background Database Database Abbreviation Availability Source References Alternate IDs Record Last Update Mentions Count
∆H3/H4 7 1.4 N*
 
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RRID:TSC_SD02039 Tetrahymena thermophila These are intermediate germline KO heterokaryons. May be early batch and not tested for somatic rescue. Final germline KO strains are #4 and #7. Non-star side. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HHT1 (TTHERM_00570560),HHT2 (TTHERM_00189180), HHF1 (TTHERM_00498190), HHF2 (TTHERM_00189170) Micronucleus: Neo into HHT1, HHF1, HHT2/HHF2 SD02039 hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; hhf1[∆::neo]/hhf1[∆::neo] (mpr1-1; mp-r, ?) TSC, Tetrahymena Stock Center TSC PMID:16908532 2025-04-20 03:37:18 0
RNH2 s KO (7)-9-1
 
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RRID:TSC_SD02831 Tetrahymena thermophila Somatic KO of RNH2 (RNase H-2) of CU427 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. RNH2 (TTHERM_00142290) Macronucleus: neo3 KO of RNH2 SD02831 chx1-1/chx1-1 (rnh2[∆::neo3]; pm-r, VI) TSC, Tetrahymena Stock Center TSC 2025-04-20 03:37:18 0
RNH2 s KO (8)-1-1
 
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RRID:TSC_SD02716 Tetrahymena thermophila Somatic KO of RNH2 (RNase H-2) of CU428 From the Gorovsky lab, University of Rochester. RNH2 (TTHERM_00142290) Macronucleus: neo3 KO of RNH2 SD02716 mpr1-1/mpr1-1 (rnh2[∆::neo3]; pm-r, VII) TSC, Tetrahymena Stock Center TSC 2025-04-20 03:37:18 0
B2KO-2
 
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RRID:TSC_SD01906 Tetrahymena thermophila Heterozygous germline transformant of BTU2 knockout. Derived from Cu428 X B2086 transformed w/ BHAB-2 (construct). When crossed to CU427, gave cyr and pmr progeny. Can mate to B2KO-6. Created 12/29/97, in soybean until 4/98. B2KO-6 mates with B2KO-1,2,3,4,5,7,8. No others mated. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. BTU2 (TTHERM_00836580) Micronucleus: H4-neo replaces BTU2 coding Macronucleus: H4-neo replaces BTU2 coding SD01906 BTU2/btu2[∆,::H4-neo]; MPR1-1/mpr1-1 (BTU2/btu1[∆,::H4-neo]; MPR1-1/mpr1-1; mp-r, pm-r, ?) TSC, Tetrahymena Stock Center TSC PMID:10831613 2025-04-20 03:37:19 0
19788-1
 
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RRID:TSC_SD03091 Tetrahymena thermophila Collected by Paul Doerder on 7/29/2008 from the pond designated SG29 in PA (latitude 41.73, longitude -79.23) Has a micronucleus. Mated with < 6 testers. SD03091 (?) TSC, Tetrahymena Stock Center TSC 2025-04-20 03:37:18 0
A2 DE-HA
 
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RRID:TSC_SD02044 Tetrahymena thermophila pDE124/6 HA rescued GTUKO 5x6 progeny having mutation @ D124-A and E126-A in GTU1-1 gene, also one HA tag@c-terminus; driven by MTT1 promoter. Needs Cd to induce. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. GTU1 (TTHERM_00079520) Micronucleus: Neo2 into GTU1 locus Macronucleus: GTU1 with mutations D124-A and E126-A and HA tag at c-teminus into the MTT1 locus, partial replacement. SD02044 gtu1[∆::neo2]/ gtu1[∆::neo2] (gtu1[∆::neo2]; MTT1/mtt1[∆, (::GTU1, D124A,E126A, HAc)]; pm-r, ?) TSC, Tetrahymena Stock Center TSC PMID:12356864
PMID:16344310
2025-04-20 03:37:18 0
C3 491 1b
 
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RRID:TSC_SD00028 Tetrahymena thermophila See Figure 1 on page 13 of Methods in Cell Biology Volume 62, Tetrahymena thermophila 2000 (Editors D.J. Asai and J.D. Forney) for and excellent diagram explaining how the inbred strains are related to each other. Submitted by Eileen Hamilton, University of California, Santa Barbara SD00028 wild type C3 (wild type C3; wild type C3, I) TSC, Tetrahymena Stock Center TSC 2025-04-20 03:37:19 0
C3 491 6a
 
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RRID:TSC_SD00033 Tetrahymena thermophila See Figure 1 on page 13 of Methods in Cell Biology Volume 62, Tetrahymena thermophila 2000 (Editors D.J. Asai and J.D. Forney) for and excellent diagram explaining how the inbred strains are related to each other. Submitted by Eileen Hamilton, University of California, Santa Barbara SD00033 wild type C3 (wild type C3; wild type C3, VI) TSC, Tetrahymena Stock Center TSC 2025-04-20 03:37:19 0
UCB404
 
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RRID:TSC_SD03302 Tetrahymena thermophila sfr10 complete KO with sfr8::MTT-CHX fully assorted. From the Winey Lab at the University of Colorado Boulder. SFR10 (TTHERM_00392670), SFR8 (TTHERM_00059100) Micronucleus: cen2-1[∆::NEO2] Macronucleus: sfr8-1[∆::MTT-CHX] SD03302 sfr10-1[∆::NEO2] (sfr10-1[∆::NEO2], sfr8-1[∆::MTT-CHX]; Basal body organization defects., ?) TSC, Tetrahymena Stock Center TSC 2025-04-20 03:37:18 0
LH0
 
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RRID:TSC_SD02694 Tetrahymena thermophila Transformation of CU428xB2086, complete knockout of mic histone linker gene with neo2 cassette inserted into Stu1 site. Paromomycin res. to 2 mg/ml Cell lines LH3 and LH6 can mate with each other. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. MLH1 (TTHERM_00471820) Macronucleus: Neo2 cassette inserted into coding of MLH1 SD02694 (mlh1[243::neo2]; pm-r, ?) TSC, Tetrahymena Stock Center TSC PMID:7606784 2025-04-20 03:37:18 0
SB2397P
 
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RRID:TSC_SD01245 Tetrahymena thermophila Resistance to 6-methylpurine was not scored for these panel members. Submitted by Eduardo Orias, University of California, Santa Barbara SD01245 CHX1[C3]/CHX1[C3]; pmr1-1/pmr1-1; MAT?/MAT? (CHX1[C3];pmr1-1; MAT?; cy-s, pm-r, ?) TSC, Tetrahymena Stock Center TSC PMID:8725229
PMID:8601476
2025-04-20 03:37:19 0
Flag-HA-CDH2-2086
 
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RRID:TSC_SD02610 Tetrahymena thermophila Neo3 in the 5’ region of CHD2 with Flag-HA tag after the ATG, complete replacement in MAC. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HPL2 (TTHERM_01337400) SD02610 (tcd1[5’neo3,FLAG HAn] complete replacement by Southern; pm-r, II) TSC, Tetrahymena Stock Center TSC 2025-04-20 03:37:18 0
SB2330A
 
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RRID:TSC_SD01256 Tetrahymena thermophila Resistance to 6-methylpurine was not scored for these panel members. Submitted by Eduardo Orias, University of California, Santa Barbara SD01256 chx1-1/chx1-1; PMR1[C3]/PMR1[C3]; MAT3/MAT3 (chx1-1; PMR1[C3]; MAT3; cy-r, pm-s, ?) TSC, Tetrahymena Stock Center TSC PMID:8725229
PMID:8601476
2025-04-20 03:37:19 0
tG2NHA3
 
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RRID:TSC_SD01412 Tetrahymena thermophila GTU (gamma tubulin) gene with c-terminal HA tag and two neo2 cassette inserted in 3’ flanking region. Partial replacement From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. GTU1 (TTHERM_00079520) Macronucleus: HA tag at c-terminus of GTU1 with neo2 in 3’ flanking region SD01412 mpr1-1/mpr1-1 (GTU1/gtu1[3’neo2neo2,HAc], VII) TSC, Tetrahymena Stock Center TSC PMID:12356864 2025-04-20 03:37:18 0
gl KO HHT2/HHF2 #10
 
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RRID:TSC_SD02623 Tetrahymena thermophila The germline knockout heterokaryon of HHT2/HHF2 and the intergenic region has neo cassette completely replacing coding region. 3 independent lines #9, #10, #11. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HHT2 (TTHERM_00189180) + HHF2 (TTHERM_00189170) Micronucleus: Neo2 replaces the HHF2 gene and HHT2 gene and the sequence between them SD02623 hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2] (mpr1-1; mp-r, II) TSC, Tetrahymena Stock Center TSC PMID:15701804 2025-04-20 03:37:19 0
gl KO HHT1#2
 
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RRID:TSC_SD02621 Tetrahymena thermophila The germline knockout heterokaryon of HHT1 gene with neo cassette completely replacing coding region. Three independent cell lines #1,#2,# 3. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HHT1 (TTHERM_00570560) Micronucleus: Neo KO of HHT1 SD02621 hht1[∆::neo2]/hht1[∆::neo2]; mpr1-1/mpr1-1 (mpr1-1; mp-r, II) TSC, Tetrahymena Stock Center TSC PMID:15701804 2025-04-20 03:37:18 0
TWI11 s KO (8) 8-1
 
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RRID:TSC_SD02864 Tetrahymena thermophila Somatic TWI 11 KO. Part of the coding sequence was replaced by neo3. In CU428 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. TWI11 (TTHERM_00144830) Macronucleus: TWI11 with neo3 SD02864 mpr1-1/mpr1-1 (twi11[∆?::neo3]; pm-r, VII) TSC, Tetrahymena Stock Center TSC 2025-04-20 03:37:18 0
SB2327H
 
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RRID:TSC_SD01259 Tetrahymena thermophila This strain must be crossed to A* for two rounds and cy-r progeny selected to generate the meiotic segregant panel member which is cy-r, pm-s, mat3. Resistance to 6-methylpurine was not scored for these panel members. Submitted by Eduardo Orias, University of California, Santa Barbara SD01259 chx1-1/chx1-1; PMR1[C3]/PMR1[C3]; MAT3/MAT3 (CHX1[C3]; cy-s, ?) TSC, Tetrahymena Stock Center TSC PMID:8601476
PMID:8725229
2025-04-20 03:37:19 0
S-H3.2+GFP/H3.3-431
 
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RRID:TSC_SD01899 Tetrahymena thermophila somatic replace H3.3 coding with H3.2+GFP, neo 2 cassette in 5’ flank of H3.3. Not sure if complete replacement. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. HHT2 (TTHERM_00189180) Macronucleus: HHT2 with GFP c-terminal tag replaces the HHT3 coding region SD01899 mpr1-1/mpr1-1 (HHT3?/htt3[5’neo2, ∆, (::HHT2,GFPc)]; pm-r, VII) TSC, Tetrahymena Stock Center TSC PMID:16908532 2025-04-20 03:37:18 0
TTMN CU428
 
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100+ mentions
RRID:TSC_SD01419 Tetrahymena thermophila CU428 transformed by pTTMN construct and cells selected with 10 mg/ml paromomycin. Partially replaced. Still has wt Metallothionein gene copies in mac as well as other alleles with neo coding. MTT1 (TTHERM_00241640) Macronucleus: Neo coding replaces MTT1 coding of some of MTT1 copies, both present SD01419 mpr1-1/mpr1-1 (pm-r, VII) TSC, Tetrahymena Stock Center TSC PMID:11891286 2025-04-20 03:37:18 110

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