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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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SD-Tg(CAG-Flpe)Qly Resource Report Resource Website |
RRID:RRRC_00843 | Rattus norvegicus | A CAG-Flpe cassette was injected into SD zygote to generate this line. The integration site is not determined.This transgenic line could be used to mate with other rat models that contains FRT sites to remove the cassette that is flanked by those FRT sites. Rat Resource and Research Center | 00843 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14695033, 14695033, RRRC_843, RRRC_0843, RRRC_00843 | RGD | 2026-11-07 03:03:46 | 0 | |||||
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SD-Tg(Ddx4-Cas9)SynblRrrc Resource Report Resource Website |
RRID:RRRC_00969 | Rattus norvegicus | rat strain designed to express Cas9 under the control of the rat Ddx4 (Vasa) regulatory elements while also retaining expression of Ddx4. The strategy entailed insertion of a P2A sequence followed by human-codon-optimized Cas9 coding sequences with nuclear localization signals near the C-terminus of the rat Ddx4 (Vasa) gene. Animals express Cas9 in the testis in the spermatogonial layer and in meiosis stages with 4N DNA content. Strain catalyzes high levels of Active Genetic Gene conversion when paired with certain Active Genetic cassettes. ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE Chenyen Lai, Oscar Alvarez, Kristen Read, Don van Fossan,Christopher M Conner, Shannon Xaing-Ru Xu, Dale O. Cowley, Valentino Gantz, David R. Webb, Kurt Jarnagin URL: Doi:10.1101/2022.08.30.505951 URL: Doi:10.1101/2022.08.30.505951 Rat Resource and Research Center | 00969 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_155260362, 155260362, RRRC_969, RRRC_0969, RRRC_00969 | RGD | 2026-11-07 03:03:46 | 0 | |||||
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SD-Tg(CAG.LoxP.EGFP)Zi Resource Report Resource Website |
RRID:RRRC_00689 | Rattus norvegicus | Random insertion of a Cre inducible expression cassette, controlled by the CAG promoter. LacZ is expressed constitutively, GFP only after Cre mediated recombination Rat Resource and Research Center | 00689 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Live Animals; Cryopreserved Sperm; Cryorecovery | RGD_10401195, 10401195, RRRC_689, RRRC_0689, RRRC_00689 | RGD | 2026-11-07 03:03:46 | 0 | |||||
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SD-Tg(Thy1.2-NIPA1) Resource Report Resource Website |
RRID:RRRC_00700 | Rattus norvegicus | Human NIPA1G106R mutation is made by site-directed mutagenesis and then inserted into Thy1.2-promotor cassette. Transgenic vector is injected into fertilized eggs to produce 2 independent lines (A, B) Rat Resource and Research Center | 00700 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm; Cryorecovery | RGD_10401212, 10401212, RRRC_700, RRRC_0700, RRRC_00700 | RGD | 2026-11-07 03:03:45 | 0 | |||||
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LEW-Tg(Col2a1-luc,-mCherry)Rmpt Resource Report Resource Website |
RRID:RRRC_00942 | Rattus norvegicus | Random insertion of transgene consisting of firefly luciferase-T2A-mCherry driven by regulatory elements of rat Col2a1, for conditional expression in chondrogenic cells. Both reporters are expressed by chondrogenic cells, leading to bioluminescence within regions of active chondrogenesis upon injecting rats with D-luciferin Rat Resource and Research Center | 00942 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_149735896, 149735896, RRRC_942, RRRC_0942, RRRC_00942 | RGD | 2026-11-07 03:03:46 | 0 | |||||
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LE-Tg(Slc6a5-icre)1Ottc Resource Report Resource Website |
RRID:RRRC_00750 | Rattus norvegicus | The transgene expresses BAC transgenic using rat GlyT2 (Slc6a5) promoter to express Cre recombinase in glycinergic neurons Optogenetics and Transgenic Technology Core, Rat Resource and Research Center | 00750 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_9588595, 9588595, RRRC_750, RRRC_0750, RRRC_00750 | RGD | 2026-11-07 03:03:45 | 0 | |||||
|
SD-Tg(RIP7-RLuc-YFP)Vpoit Resource Report Resource Website |
RRID:RRRC_00757 | Rattus norvegicus | Transgene: RIP7-RLuc-YFP. This transgene expresses a renilla luciferase-YFP fusion protein under control of the rat insulin 2 gene promoter (RIP7). Rat Resource and Research Center | 00757 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_11084931, 11084931, RRRC_757, RRRC_0757, RRRC_00757 | RGD | 2026-11-07 03:03:46 | 0 | |||||
|
SD-Tg(CAG-GFP-LacZ)Appsc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00879 | Rattus norvegicus | A transgenic line carrying random insertion of transgene cassette CAG-LSL-GFP-LacZ (LSL: loxp-Stop-Loxp). It is used as a Cre reporter/test line expressing GFP and lacZ. Used as lineage tracing tool rat line by mating with tissue specific cre or cre/ERT2 line Deposited at Rat Resource and Research Center | 00879 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_149735366, 149735366, RRRC_879, RRRC_0879, RRRC_00879 | RGD | 2026-11-07 03:03:46 | 2 | |||||
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LE-Tg(cFos-LacZ)1Ottc Resource Report Resource Website |
RRID:RRRC_00759 | Rattus norvegicus | The transgene contains reporter rat expressing beta-galactosidase in cFos expressing cells Optogenetics and Transgenic Technology Core, Rat Resource and Research Center | 00759 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_9588581, 9588581, RRRC_759, RRRC_0759, RRRC_00759 | RGD | 2026-11-07 03:03:45 | 0 | |||||
|
LE-Tg(cFos-TetO-iCre)4Ottc Resource Report Resource Website |
RRID:RRRC_00760 | Rattus norvegicus | The transgene contains Cre recombinase expressed from cFos promoter and controllable by Tet activator/repressor Optogenetics and Transgenic Technology Core, Rat Resource and Research Center | 00760 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_9588583, 9588583, RRRC_760, RRRC_0760, RRRC_00760 | RGD | 2026-11-07 03:03:45 | 0 | |||||
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LE-Tg(EEF1A1-TetR)1Ottc Resource Report Resource Website |
RRID:RRRC_00761 | Rattus norvegicus | The transgene expresses TetR using "ubiquitous" promoter; to be used in combination with TetO containing rats or viral vectors Optogenetics and Transgenic Technology Core, Rat Resource and Research Center | 00761 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_9588587, 9588587, RRRC_761, RRRC_0761, RRRC_00761 | RGD | 2026-11-07 03:03:45 | 0 | |||||
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LE-Tg(EEF1A1-TetR)2Ottc Resource Report Resource Website |
RRID:RRRC_00735 | Rattus norvegicus | The transgene expresses TetR using "ubiquitous" promoter; to be used in combination with TetO containing rats or viral vectors Optogenetics and Transgenic Technology Core, Rat Resource and Research Center | 00735 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_9588589, 9588589, RRRC_735, RRRC_0735, RRRC_00735 | RGD | 2026-11-07 03:03:45 | 0 | |||||
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LE-Tg(Cx3cr1-cre/ERT2)3Ottc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00858 | Rattus norvegicus | This strain was generated by microinjection of LE embyos with a BAC DNA containing the Cx3cr1-cre/ERT2 transgene which is composed of cre/ERT2 recombinase gene driven by the rat genomic Cx3cr1promoter. Rat Resource and Research Center | 00858 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_13441557, 13441557, RRRC_858, RRRC_0858, RRRC_00858 | RGD | 2026-11-07 03:03:46 | 2 | |||||
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LEW-Tg(CAG-OFP)Pic Resource Report Resource Website |
RRID:RRRC_00746 | Rattus norvegicus | random insertion of a transgene carrying orange fluorescent protein (OFP) driven by the CAG promoter Rat Resource and Research Center | 00746 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm; Cryorecovery | RGD_11040565, 11040565, RRRC_746, RRRC_0746, RRRC_00746 | RGD | 2026-11-07 03:03:46 | 0 | |||||
|
SD-Tg(Th-SNCA*)4Ins Resource Report Resource Website |
RRID:RRRC_00635 | Rattus norvegicus | the transgene overexpressing duble-mutated human alpha-synuclein (A53T and A30P) under the control of rat tyrosine hydroxylase (Th)promoter was microinjected into SD ovocytes to generate 3 transgenic rat lines. This line, MA4, shows learning and memory deficits beginning at 9 months of age. It is a model for dementia with Lewy bodies. Rat Resource and Research Center | 00635 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_7245523, 7245523, RRRC_635, RRRC_0635, RRRC_00635 | RGD | 2026-11-07 03:03:45 | 0 | |||||
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SD-Tg(Th-SNCA*)3Ins Resource Report Resource Website |
RRID:RRRC_00634 | Rattus norvegicus | the transgene overexpressing double-mutated human alpha-synuclein (A53T and A30P) under the control of rat tyrosine hydroxylase (Th)promoter was microinjected into SD ovocytes to generate 3 transgenic rat lines. The MA3 line has pre-symptomatic olfactory deficits (beginning at 6 months of age) and motor deficits starting at a later age (19 months of age). Rat Resource and Research Center | 00634 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_7245521, 7245521, RRRC_634, RRRC_0634, RRRC_00634 | RGD | 2026-11-07 03:03:45 | 0 | |||||
|
SD-Tg(ACE2)955Bryd Resource Report Resource Website 1+ mentions |
RRID:RRRC_01001 | Rattus norvegicus | Genetic Alteration(s):human ACE2 gene under expression of the human ACE2 promoter. Thirty (30) copies of the transgene are randomly integrated into an as yet unknown insertion site. Deposited at Rat Resource and Research Center | 01001 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Embryo (as of 2025-11-06) | RGD_629006610, 629006610, RRRC_1001, RRRC_01001 | RGD | 2026-11-07 03:03:47 | 1 | |||||
|
SD-Foxn1rnuTg(Rho-S334X)3LavRrrc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00539 | Rattus norvegicus | This strain was created by crossing “SD-Tg(Rho*S334X)3Lav, RGD: 1358302,”( also known as, SD-Tg(S334ter)3Lav , homozygous for a mutated mouse rhodopsin transgene Rho S334ter-3) with “NTac:NIH-Foxn1rnu, RGD: 7246928,” (also known as NTac:NIH-Whn (NIH nude) males (foxn1-/-). By selective breeding, all animals of this strain (RRRC#539) are homozygous for the rhodopsin mutation, and homo- or hemizygous for the foxn1 mutation. Rat Resource and Research Center | 00539 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryorecovery (as of 2025-09-03) | RGD_626189117, 626189117, RRRC_539, RRRC_0539, RRRC_00539 | RGD | 2026-11-07 03:03:47 | 9 | |||||
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SD-Tg(Thy1-APPD)BWevn Resource Report Resource Website |
RRID:RRRC_01051 | Rattus norvegicus | These rats produce human familial CAA Dutch E22Q mutant amyloid APPB2-protein in brain and develop arteriolar CAA type-2. The deposition of fibrillar APPB2 promotes arteriolar smooth muscle cell loss and cerebral microhemorrhages that can be detected by magnetic resonance imaging and confirmed by histopathology. Random integration of a transgene consisting of 2.1 kb of human APP (isoform 770) cDNA carrying the Dutch E693Q mutation cloned between exons II and IV of a Thy1.2 expression cassette. This leads to expression of chimeric mutant human A beta PP under control of the neuronal specific Thy1.2 promoter. The integration site of the transgene is unknown. Rat Resource and Research Center | 01051 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryorecovery (as of 2025-10-30) | RGD_629006509, 629006509, RRRC_1051, RRRC_01051 | RGD | 2026-11-07 03:03:47 | 0 | |||||
|
SD-Tg(UBC-EGFP)1BalRrrc Resource Report Resource Website |
RRID:RRRC_00052 | Rattus norvegicus | This transgenic strain contains the enhanced green fluorescent protein gene under the control of the human ubiquitin-C promoter with a the woodchuck hepatitis virus posttranscriptional regulatory element (WRE). This transgenic strain was made by injecting the lentivirus vector containing the GFP construct (vector name FUGW) into SD rat embryos. Animals that exhibited fluorescence of tails where then mated. The colony was transferred from Carlos Lois, California Institute of Technology, Pasedena, California to the Rat Resource and Research Center in 2002. This strain has been maintained by inter-breeding of carrier animals. Rat Resource and Research Center | 00052 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-07-10) | RGD_738122, 738122, RRRC_52, RRRC_052, RRRC_0052, RRRC_00052 | RGD | 2026-11-07 03:03:40 | 0 |
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