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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00050586
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:35224463
Synonyms: EMPTY
Notes: [2022-02-11T04:53:40.239Z WBPerson12028] New Strain: mls-2(vy247[mNG::SEC::mls-2 knock-in]) X; WBPaper00062471
Proper citation: RRID:WB-STRAIN:WBStrain00050586 Copy
http://www.wormbase.org/db/get?name=WBStrain00050584
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:33392968
Synonyms: EMPTY
Notes: [2022-01-28T00:07:28.948Z WBPerson12028] New Strain: [HSF-1::GFP], WBPaper00060830
Proper citation: RRID:WB-STRAIN:WBStrain00050584 Copy
http://www.wormbase.org/db/get?name=WBStrain00050588
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:33634121
Synonyms: xnIs3[par-6:PAR-6::GFP + unc-119(+)]; ltIs44 [pie-1p-mCherry::PH (PLC1delta1) + unc-119(+)]V.
Notes: Generated from the supplementary table in Kunz et al 2021 - BV43 - (FT17xOD70) xnIs3[par-6:PAR-6::GFP + unc-119(+)]; ltIs44 [pie-1p-mCherry::PH (PLC1delta1) + unc-119(+)]V.|"Generated via a cross of FT17xOD70"
Proper citation: RRID:WB-STRAIN:WBStrain00050588 Copy
http://www.wormbase.org/db/get?name=WBStrain00050629
Source Database: WormBase (WB)
Availability: unknown
Synonyms: kyIs262 IV; acEx25.
Notes: kyIs262 [unc-86::myr::GFP + odr-1::RFP] IV. acEx25 [odr-1p::srbc-48::GFP]. Maintain by picking GFP+ to maintain array. Extra-chromosomal GFP expression in AWC neurons. Integrated RFP expression in AWB and AWC. acEx25 rescues srbc-48 mediated defects. Reference: Kaur S & Aballay A. Cell Reports. 2020 May 19; 31(7): 107662. PMID: 32433971|"Made_by: Supender Kaur"
Proper citation: RRID:WB-STRAIN:WBStrain00050629 Copy
http://www.wormbase.org/db/get?name=WBStrain00050572
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:32905774
Synonyms: (dma-1(yan126[pat-3sp]) I;catp-8(yan22) IV; wyIs592).
Notes: Generated from papers flagged positive during the last month for data type afp_otherstrain and contains genotype and gene data.
Proper citation: RRID:WB-STRAIN:WBStrain00050572 Copy
http://www.wormbase.org/db/get?name=WBStrain00050571
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:32905774
Synonyms: (dma-1(yan51) I; wyIs592).
Notes: Generated from papers flagged positive during the last month for data type afp_otherstrain and contains genotype and gene data.
Proper citation: RRID:WB-STRAIN:WBStrain00050571 Copy
http://www.wormbase.org/db/get?name=WBStrain00050574
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:32905774
Synonyms: (crt-1(yan77) V; wyIs592).
Notes: Generated from papers flagged positive during the last month for data type afp_otherstrain and contains genotype and gene data.
Proper citation: RRID:WB-STRAIN:WBStrain00050574 Copy
http://www.wormbase.org/db/get?name=WBStrain00050578
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:34706230
Synonyms: catp-8(yan22) egl-20(yan129 [pat-3sp]); lqIs58
Notes: Generated from papers flagged positive during the last month for data type afp_otherstrain and contains genotype and gene data.
Proper citation: RRID:WB-STRAIN:WBStrain00050578 Copy
http://www.wormbase.org/db/get?name=WBStrain00050619
Source Database: WormBase (WB)
Affected Genes: WBGene00016216(pals-22)
Genomic Alteration: WBGene00016216(pals-22)
Availability: unknown
Synonyms: pals-22(kea8[pals-22::GFP::degron]) III.
Notes: C-terminal GFP::degron tag was inserted into the endogenous pals-22 locus. Generated in N2 background. Reference: Willis AR, et al. Sci Adv. 2021 May 5;7(19):eabf3114. PMID: 33952520 [NOTE: pals22(kea8) is a C-terminal tag; the methods section of the paper incorrectly describes the tag as an N-terminal insertion.]|"Made_by: Winnie Zhao"
Proper citation: RRID:WB-STRAIN:WBStrain00050619 Copy
http://www.wormbase.org/db/get?name=WBStrain00050618
Source Database: WormBase (WB)
Affected Genes: WBGene00003020(lin-35)
Genomic Alteration: WBGene00003020(lin-35)
Availability: unknown
Synonyms: lin-35(kea7[lin-35p::degron::GFP::lin-35]) I.
Notes: Made_by: Winnie Zhao|"N-terminal degron::GFP tag was inserted into the endogenous lin-35 locus. Generated in N2 background. Reference: Willis AR, et al. Sci Adv. 2021 May 5;7(19):eabf3114. PMID: 33952520 [NOTE: lin-35(kea7) is an N-terminal tag; the methods section of the paper incorrectly describes the tag as a C-terminal insertion.]"
Proper citation: RRID:WB-STRAIN:WBStrain00050618 Copy
http://www.wormbase.org/db/get?name=WBStrain00050682
Source Database: WormBase (WB)
Affected Genes: WBGene00012802(set-25)|WBGene00016313(set-4)|WBGene00019883(met-2)
Genomic Alteration: WBGene00012802(set-25), WBGene00016313(set-4), WBGene00019883(met-2)
Availability: unknown
Synonyms: gwSi17 set-4(n4600) II; met-2(n4256) set-25(n5021) III; gwIs4 X.
Notes: gwSi17 [cec4p::cec4::WmCherry::cec4 3'UTR] II. gwIs4 [baf-1p::GFP-lacI::let-858 3UTR + myo-3p::RFP] X. Worms are slow growing with reduced brood size and become sterile at elevated temperatures. Expresses GFP-LacI throughout development from early embryogenesis, forming a large spot at the lacO array. Worms have red muscle (from L1 stage). CEC-4::WmCherry is visible at the nuclear periphery in embryos and L1 stage animals. Reference: Cabianca DS, et al. Nature 2019 May;569(7758):734-739. PMID: 31118512
Proper citation: RRID:WB-STRAIN:WBStrain00050682 Copy
http://www.wormbase.org/db/get?name=WBStrain00050680
Source Database: WormBase (WB)
Affected Genes: WBGene00012802(set-25)|WBGene00019883(met-2)
Genomic Alteration: WBGene00012802(set-25), WBGene00019883(met-2)
Availability: unknown
Synonyms: met-2(n4256) set-25(n5021) III.
Notes: Made_by: BenjaminD. Towbin|"Worms are slow growing with reduced brood size and become sterile at elevated temperatures. Mutants co-segregate with ~ 20cM distance. Reference: Towbin BD, et al. Cell. 2012 Aug 31;150(5):934-47. PMID: 22939621"
Proper citation: RRID:WB-STRAIN:WBStrain00050680 Copy
http://www.wormbase.org/db/get?name=WBStrain00050686
Source Database: WormBase (WB)
Availability: unknown
Synonyms: bqSi447 II; bqSi495 IV; ygIs1.
Notes: bqSi447 [hsp16.41p::FRT::mCherry::his-58::FRT::GFP::dam + unc-119(+)] II. bqSi495 [myo-3p::FLP::D5 + unc-119(+)] IV. ygIs1 [baf-1p::GFP::lamin(wt) + unc-119(+)]. Strain expressing muscle specific DAM::GFP, used as a control for muscle specific EMR-DamID. Strain also has low level over-expression of GFP::LMN-1. Might still carry unc-119(ed3) or (ed9) in background. Reference: Harr JC, et al. Genes Dev. 2020 Apr 1;34(7-8):560-579. PMID: 32139421|"Made_by: Jennifer Harr"
Proper citation: RRID:WB-STRAIN:WBStrain00050686 Copy
http://www.wormbase.org/db/get?name=WBStrain00050685
Source Database: WormBase (WB)
Availability: unknown
Synonyms: bqsi433 II; bqSi495 IV; ygIs1.
Notes: bqsi433 [hsp16.41p::FRT::mCherry::his-58::FRT::dam::emr-1 + unc-119(+)] II. bqSi495 [myo-3p::FLP::D5 + unc-119(+)] IV. ygIs1 [baf-1p::GFP::lamin(wt) + unc-119(+)]. Strain used to perform muscle specific EMR-DamID, to map lamina-associated domains (LADs). Strain also has low level over-expression of GFP::LMN-1. Might still carry unc-119(ed3) or (ed9) in background. Reference: Harr JC, et al. Genes Dev. 2020 Apr 1;34(7-8):560-579. PMID: 32139421|"Made_by: Jennifer Harr"
Proper citation: RRID:WB-STRAIN:WBStrain00050685 Copy
http://www.wormbase.org/db/get?name=WBStrain00050684
Source Database: WormBase (WB)
Affected Genes: WBGene00019883(met-2)
Genomic Alteration: WBGene00019883(met-2)
Availability: unknown
Synonyms: met-2(gw1419[met-2::FLAG::TEV::mCherry]) III.
Notes: Made_by: Micol Guidi|"Superficially wild-type. Endogenously tagged met-2 locus, with MET-2::mCherry signal detectable in all germline and somatic tissues. Reference: Delaney CE, et al. J Cell Biol. 2019 Mar 4;218(3):820-838. PMID: 30737265"
Proper citation: RRID:WB-STRAIN:WBStrain00050684 Copy
http://www.wormbase.org/db/get?name=WBStrain00050683
Source Database: WormBase (WB)
Affected Genes: WBGene00003082(lsm-8)|WBGene00003514(myo-2)|WBGene00006789(unc-54)
Genomic Alteration: WBGene00003082(lsm-8), WBGene00003514(myo-2), WBGene00006789(unc-54)
Availability: unknown
Synonyms: lsm-8 (xe17[myo-2p::mCherry::unc-54 3'UTR]) IV/nT1 [qIs51] (IV;V); pkIs1582 V/nT1 [qIs51] (IV;V).
Notes: Made_by: Florian Aeschlimann|"pkIs1582 [let-858::GFP + rol-6(su1006)] V. Homozygous lethal lsm-8 deletion balanced by GFP-marked nT1 translocation. xe17 generated by CRISPR/Cas9-engineered replacement of the gene with a red pharyngeal marker. lsm-8 heterozygotes are wild-type (will roll in this case because of pkIs1582) green & red pharynx, and will segregate rolling heterozygotes (green & red pharynx), arrested nT1[qIs51] aneuploids (only green pharynx), and lsm-8 homozygotes (only red pharynx). Homozygous nT1[qIs51] inviable. Pick rollers with green & red pharynx and check for correct segregation of progeny to maintain. Reference: Mattout A, et al. Nat Cell Biol. 2020 May;22(5):579-590. PMID: 32251399"
Proper citation: RRID:WB-STRAIN:WBStrain00050683 Copy
http://www.wormbase.org/db/get?name=WBStrain00050721
Source Database: WormBase (WB)
Affected Genes: WBGene00001569(meg-3)|WBGene00016485(meg-4)
Genomic Alteration: WBGene00001569(meg-3), WBGene00016485(meg-4)
Availability: unknown
Synonyms: meg-3(ax3051[meg-3::OLLAS]) meg-4(ax3052) X.
Notes: P granule size reduced, detection of MEG-3 by anti-OLLAS antibody. References: Smith, J. et al. Elife. 2016 Dec 3;5:e21337. doi: 10.7554/eLife.21337. PMID: 27914198 Schmidt H, bioRxiv 2020.10.15.340570 (2020) doi:10.1101/2020.10.15.340570.
Proper citation: RRID:WB-STRAIN:WBStrain00050721 Copy
http://www.wormbase.org/db/get?name=WBStrain00050727
Source Database: WormBase (WB)
Affected Genes: WBGene00022257(puf-11)
Genomic Alteration: WBGene00022257(puf-11)
Availability: unknown
Synonyms: puf-11(q1128[3xV5::puf-11]) IV.
Notes: 3x V5 epitope tags inserted into endogenous puf-11 locus. Expresses functional 3x V5-tagged PUF-11. Reference: Haupt KA, Genetics. 2020 Jan;214(1):147-161. PMID: 31740451
Proper citation: RRID:WB-STRAIN:WBStrain00050727 Copy
http://www.wormbase.org/db/get?name=WBStrain00050671
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00002225(klp-15)|WBGene00002226(klp-16)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00002225(klp-15), WBGene00002226(klp-16)
Availability: unknown
Synonyms: klp-15(ok1958) klp-16(or1952)/tmC18[dpy-5(tmIs1236)] I; ltIs37 IV; ruIs57.
Notes: itIs37 [pie-1p::mCherry::H2B::pie-1 3'UTR + unc-119(+)] IV. ruIs57 [pie-1p::GFP::tubulin + unc-119(+)]. tmC18 balancer marked with myo-2p::mCherry and Dpy. Heterozygotes are wild-type with pharyngeal mCherry, and segregate mCherry+ heterozygotes, tmC18 homozygotes (mCherry+ Dpy) and non-mCherry klp-15/16 homozygotes. Homozygous double deletion mutants are fertile but produced reduced brood sizes with highly penetrant embryonic lethality; will also segregate some males. Reference: Chuang CH, et al., Biology Open 2020 9: bio052308 doi: 10.1242/bio.052308 Published 25 June 2020|"ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. ruIs57 [pie-1p::GFP::tubulin + unc-119(+)]. tmC18 balancer marked with myo-2p::mCherry and Dpy. Heterozygotes are wild-type with pharyngeal mCherry, and segregate mCherry+ heterozygotes, tmC18 homozygotes (mCherry+ Dpy) and non-mCherry klp-15/16 homozygotes. Homozygous double deletion mutants are fertile but produced reduced brood sizes with highly penetrant embryonic lethality; will also segregate some males. [NOTE: the ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV transgene was previously annotated as itIs37 in this strain. The correct name of the transgene is ltIs37 and not itIs37.] Reference: Chuang CH, et al., Biology Open 2020 9: bio052308 doi: 10.1242/bio.052308 Published 25 June 2020"
Proper citation: RRID:WB-STRAIN:WBStrain00050671 Copy
http://www.wormbase.org/db/get?name=WBStrain00050674
Source Database: WormBase (WB)
Affected Genes: WBGene00001067(dpy-5)|WBGene00002225(klp-15)|WBGene00002226(klp-16)|WBGene00004027(pie-1)|WBGene00006843(unc-119)|WBGene00008107(aspm-1)
Genomic Alteration: WBGene00001067(dpy-5), WBGene00002225(klp-15), WBGene00002226(klp-16), WBGene00004027(pie-1), WBGene00006843(unc-119), WBGene00008107(aspm-1)
Availability: unknown
Synonyms: klp-15(ok1958) aspm-1(syb1260[gfp::aspm-1]) klp-16(or1952) /tmC18[dpy-5(tmIs1236)] I; ltIs37[pie-1p::mCherry::H2B::pie-1 3'UTR + unc-119(+)] IV
Notes: itIs37 [pie-1p::mCherry::H2B::pie-1 3'UTR + unc-119(+)] IV. ruIs57 [pie-1p::GFP::tubulin + unc-119(+)]. GFP tag inserted into endogenous aspm-1 locus. tmC18 balancer marked with myo-2p::mCherry and Dpy. Heterozygotes are wild-type with pharyngeal mCherry, and segregate mCherry+ heterozygotes, tmC18 homozygotes (mCherry+ Dpy) and non-mCherry triple mutant homozygotes. Homozygous triple mutants are fertile but produced reduced brood sizes with highly penetrant embryonic lethality; will also segregate some males. Reference: Chuang CH, et al., Biology Open 2020 9: bio052308 doi: 10.1242/bio.052308 Published 25 June 2020|"ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. ruIs57 [pie-1p::GFP::tubulin + unc-119(+)]. GFP tag inserted into endogenous aspm-1 locus. tmC18 balancer marked with myo-2p::mCherry and Dpy. Heterozygotes are wild-type with pharyngeal mCherry, and segregate mCherry+ heterozygotes, tmC18 homozygotes (mCherry+ Dpy) and non-mCherry triple mutant homozygotes. Homozygous triple mutants are fertile but produced reduced brood sizes with highly penetrant embryonic lethality; will also segregate some males. [NOTE: the ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV transgene was previously annotated as itIs37 in this strain. The correct name of the transgene is ltIs37 and not itIs37.] Reference: Chuang CH, et al., Biology Open 2020 9: bio052308 doi: 10.1242/bio.052308 Published 25 June 2020"
Proper citation: RRID:WB-STRAIN:WBStrain00050674 Copy
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