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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00038506
Source Database: WormBase (WB)
Availability: available
Synonyms: Whole-genome sequenced strain.
Alternate IDs: WB-STRAIN:VC20573, CGC_VC20573
Notes: Made_by: Vancouver KO Group|"Million Mutation Project strain. This strain was isolated after EMS mutagenesis of VC2010, propagated clonally through F10 to drive mutations to homozygosity, and subjected to whole-genome sequencing. It is homozygous for a large number of mutations determined from sequence data. It may also carry large copy number variations that are not homozygous. Alleles numbered between gk100000 and gk962522 are homozygous; those numbered from gk962523 up should be assumed to be non-homozygous. A graphical representation of these large copy number differences can be seen in the Plot section for each strain on the MMP web site ( URL: genome.sfu.ca/mmp/)."|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00038506 Copy
http://www.wormbase.org/db/get?name=WBStrain00038507
Source Database: WormBase (WB)
Availability: available
Synonyms: Whole-genome sequenced strain.
Alternate IDs: WB-STRAIN:VC20574, CGC_VC20574
Notes: Made_by: Vancouver KO Group|"Million Mutation Project strain. This strain was isolated after EMS mutagenesis of VC2010, propagated clonally through F10 to drive mutations to homozygosity, and subjected to whole-genome sequencing. It is homozygous for a large number of mutations determined from sequence data. It may also carry large copy number variations that are not homozygous. Alleles numbered between gk100000 and gk962522 are homozygous; those numbered from gk962523 up should be assumed to be non-homozygous. A graphical representation of these large copy number differences can be seen in the Plot section for each strain on the MMP web site ( URL: genome.sfu.ca/mmp/)."|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00038507 Copy
http://www.wormbase.org/db/get?name=WBStrain00038588
Source Database: WormBase (WB)
Availability: available
Synonyms: Whole-genome sequenced strain.
Alternate IDs: WB-STRAIN:VC20657, CGC_VC20657
Notes: Made_by: Vancouver KO Group|"Million Mutation Project strain. This strain was isolated after EMS mutagenesis of VC2010, propagated clonally through F10 to drive mutations to homozygosity, and subjected to whole-genome sequencing. It is homozygous for a large number of mutations determined from sequence data. It may also carry large copy number variations that are not homozygous. Alleles numbered between gk100000 and gk962522 are homozygous; those numbered from gk962523 up should be assumed to be non-homozygous. A graphical representation of these large copy number differences can be seen in the Plot section for each strain on the MMP web site ( URL: genome.sfu.ca/mmp/)."|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00038588 Copy
http://www.wormbase.org/db/get?name=WBStrain00038589
Source Database: WormBase (WB)
Availability: available
Synonyms: Whole-genome sequenced strain.
Alternate IDs: WB-STRAIN:VC20658, CGC_VC20658
Notes: Made_by: Vancouver KO Group|"Million Mutation Project strain. This strain was isolated after EMS mutagenesis of VC2010, propagated clonally through F10 to drive mutations to homozygosity, and subjected to whole-genome sequencing. It is homozygous for a large number of mutations determined from sequence data. It may also carry large copy number variations that are not homozygous. Alleles numbered between gk100000 and gk962522 are homozygous; those numbered from gk962523 up should be assumed to be non-homozygous. A graphical representation of these large copy number differences can be seen in the Plot section for each strain on the MMP web site ( URL: genome.sfu.ca/mmp/)."|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00038589 Copy
http://www.wormbase.org/db/get?name=WBStrain00038586
Source Database: WormBase (WB)
Availability: available
Synonyms: Whole-genome sequenced strain.
Alternate IDs: WB-STRAIN:VC20655, CGC_VC20655
Notes: Made_by: Vancouver KO Group|"Million Mutation Project strain. This strain was isolated after EMS mutagenesis of VC2010, propagated clonally through F10 to drive mutations to homozygosity, and subjected to whole-genome sequencing. It is homozygous for a large number of mutations determined from sequence data. It may also carry large copy number variations that are not homozygous. Alleles numbered between gk100000 and gk962522 are homozygous; those numbered from gk962523 up should be assumed to be non-homozygous. A graphical representation of these large copy number differences can be seen in the Plot section for each strain on the MMP web site ( URL: genome.sfu.ca/mmp/)."|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00038586 Copy
http://www.wormbase.org/db/get?name=WBStrain00038505
Source Database: WormBase (WB)
Availability: available
Synonyms: Whole-genome sequenced strain.
Alternate IDs: WB-STRAIN:VC20572, CGC_VC20572
Notes: Made_by: Vancouver KO Group|"Million Mutation Project strain. This strain was isolated after EMS mutagenesis of VC2010, propagated clonally through F10 to drive mutations to homozygosity, and subjected to whole-genome sequencing. It is homozygous for a large number of mutations determined from sequence data. It may also carry large copy number variations that are not homozygous. Alleles numbered between gk100000 and gk962522 are homozygous; those numbered from gk962523 up should be assumed to be non-homozygous. A graphical representation of these large copy number differences can be seen in the Plot section for each strain on the MMP web site ( URL: genome.sfu.ca/mmp/)."|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00038505 Copy
http://www.wormbase.org/db/get?name=WBStrain00038591
Source Database: WormBase (WB)
Availability: available
Synonyms: Whole-genome sequenced strain.
Alternate IDs: WB-STRAIN:VC20660, CGC_VC20660
Notes: Made_by: Vancouver KO Group|"Million Mutation Project strain. This strain was isolated after EMS mutagenesis of VC2010, propagated clonally through F10 to drive mutations to homozygosity, and subjected to whole-genome sequencing. It is homozygous for a large number of mutations determined from sequence data. It may also carry large copy number variations that are not homozygous. Alleles numbered between gk100000 and gk962522 are homozygous; those numbered from gk962523 up should be assumed to be non-homozygous. A graphical representation of these large copy number differences can be seen in the Plot section for each strain on the MMP web site ( URL: genome.sfu.ca/mmp/)."|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00038591 Copy
http://www.wormbase.org/db/get?name=WBStrain00038592
Source Database: WormBase (WB)
Availability: available
Synonyms: Whole-genome sequenced strain.
Alternate IDs: WB-STRAIN:VC20661, CGC_VC20661
Notes: Made_by: Vancouver KO Group|"Million Mutation Project strain. This strain was isolated after EMS mutagenesis of VC2010, propagated clonally through F10 to drive mutations to homozygosity, and subjected to whole-genome sequencing. It is homozygous for a large number of mutations determined from sequence data. It may also carry large copy number variations that are not homozygous. Alleles numbered between gk100000 and gk962522 are homozygous; those numbered from gk962523 up should be assumed to be non-homozygous. A graphical representation of these large copy number differences can be seen in the Plot section for each strain on the MMP web site ( URL: genome.sfu.ca/mmp/)."|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00038592 Copy
http://www.wormbase.org/db/get?name=WBStrain00038590
Source Database: WormBase (WB)
Availability: available
Synonyms: Whole-genome sequenced strain.
Alternate IDs: WB-STRAIN:VC20659, CGC_VC20659
Notes: Made_by: Vancouver KO Group|"Million Mutation Project strain. This strain was isolated after EMS mutagenesis of VC2010, propagated clonally through F10 to drive mutations to homozygosity, and subjected to whole-genome sequencing. It is homozygous for a large number of mutations determined from sequence data. It may also carry large copy number variations that are not homozygous. Alleles numbered between gk100000 and gk962522 are homozygous; those numbered from gk962523 up should be assumed to be non-homozygous. A graphical representation of these large copy number differences can be seen in the Plot section for each strain on the MMP web site ( URL: genome.sfu.ca/mmp/)."|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00038590 Copy
http://www.wormbase.org/db/get?name=WBStrain00038595
Source Database: WormBase (WB)
Availability: available
Synonyms: Whole-genome sequenced strain.
Alternate IDs: WB-STRAIN:VC20664, CGC_VC20664
Notes: Made_by: Vancouver KO Group|"Million Mutation Project strain. This strain was isolated after EMS mutagenesis of VC2010, propagated clonally through F10 to drive mutations to homozygosity, and subjected to whole-genome sequencing. It is homozygous for a large number of mutations determined from sequence data. It may also carry large copy number variations that are not homozygous. Alleles numbered between gk100000 and gk962522 are homozygous; those numbered from gk962523 up should be assumed to be non-homozygous. A graphical representation of these large copy number differences can be seen in the Plot section for each strain on the MMP web site ( URL: genome.sfu.ca/mmp/)."|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00038595 Copy
http://www.wormbase.org/db/get?name=WBStrain00050274
Source Database: WormBase (WB)
Affected Genes: WBGene00011032(ddx-52)
Genomic Alteration: WBGene00011032(ddx-52)
Availability: available
Source References: PMID:32293562, PMID:32652074, PMID:32847964, PMID:33006972, PMID:32958476, PMID:32997655, PMID:33027250, PMID:33034119, PMID:33033228, PMID:33033182, PMID:33065011, PMID:33060131, PMID:33157031, PMID:33096249, PMID:33264285, PMID:33234550, PMID:33239401, PMID:33319748, PMID:33349622, PMID:33361147, PMID:33397797, PMID:33493646, PMID:33516872, PMID:33547005, PMID:33638604, PMID:33677541, PMID:33627403, PMID:33793670, PMID:33820857, PMID:33827942, PMID:33871019, PMID:33963848, PMID:34032213, PMID:34059684, PMID:34114562, PMID:34166401, PMID:34197450, PMID:34195824, PMID:34003969, PMID:34232959, PMID:34244496, PMID:34260587, PMID:34288362, PMID:34312566, PMID:34323218, PMID:34321666, PMID:34397094, PMID:34429473, PMID:34429379, PMID:34469721, PMID:34467850, PMID:34465863, PMID:34373460, PMID:34496246, PMID:34499028, PMID:37039075
Synonyms: ddx-52(gc51) I.
Alternate IDs: CGC_MC817
Notes: ddx-52 mutant|"New Strain - Generated from papers flagged positive during the last month for data type afp_strain/other_strain."|"Temperature-sensitive: can be maintained at 20C, larval arrest (L3) at 25C. gc51 mutants are hypoxia-resistant. Reference: Itani OA, et al. Current Biology. 2021/01/11/ 2021;31(1):128-137.e5. PMID: 33157031."|"WBStrain mapped, WBPaper00060602 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00050274 Copy
http://www.wormbase.org/db/get?name=WBStrain00050292
Source Database: WormBase (WB)
Affected Genes: WBGene00017989(nol-10)
Genomic Alteration: WBGene00017989(nol-10)
Availability: available
Source References: PMID:32293562, PMID:32652074, PMID:32847964, PMID:33006972, PMID:32958476, PMID:32997655, PMID:33027250, PMID:33034119, PMID:33033228, PMID:33033182, PMID:33065011, PMID:33060131, PMID:33157031, PMID:33096249, PMID:33264285, PMID:33234550, PMID:33239401, PMID:33319748, PMID:33349622, PMID:33361147, PMID:33397797, PMID:33493646, PMID:33516872, PMID:33547005, PMID:33638604, PMID:33677541, PMID:33627403, PMID:33793670, PMID:33820857, PMID:33827942, PMID:33871019, PMID:33963848, PMID:34032213, PMID:34059684, PMID:34114562, PMID:34166401, PMID:34197450, PMID:34195824, PMID:34003969, PMID:34232959, PMID:34244496, PMID:34260587, PMID:34288362, PMID:34312566, PMID:34323218, PMID:34321666, PMID:34397094, PMID:34429473, PMID:34429379, PMID:34469721, PMID:34467850, PMID:34465863, PMID:34373460, PMID:34496246, PMID:34499028
Synonyms: nol-10(gc58) IV.
Alternate IDs: CGC_MC896
Notes: Gain-of-function mutation. Suppresses hypoxia resistance of ddx-52(gc51). Reference: Itani OA, et al. Current Biology. 2021/01/11/ 2021;31(1):128-137.e5. PMID: 33157031.|"New Strain - Generated from papers flagged positive during the last month for data type afp_strain/other_strain."|"WBStrain mapped, WBPaper00060602 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00050292 Copy
http://www.wormbase.org/db/get?name=WBStrain00050290
Source Database: WormBase (WB)
Affected Genes: WBGene00006739(ulp-4)
Genomic Alteration: WBGene00006739(ulp-4)
Availability: available
Source References: PMID:32293562, PMID:32652074, PMID:32847964, PMID:33006972, PMID:32958476, PMID:32997655, PMID:33027250, PMID:33034119, PMID:33033228, PMID:33033182, PMID:33065011, PMID:33060131, PMID:33157031, PMID:33096249, PMID:33264285, PMID:33234550, PMID:33239401, PMID:33319748, PMID:33349622, PMID:33361147, PMID:33397797, PMID:33493646, PMID:33516872, PMID:33547005, PMID:33638604, PMID:33677541, PMID:33627403, PMID:33793670, PMID:33820857, PMID:33827942, PMID:33871019, PMID:33963848, PMID:34032213, PMID:34059684, PMID:34114562, PMID:34166401, PMID:34197450, PMID:34195824, PMID:34003969, PMID:34232959, PMID:34244496, PMID:34260587, PMID:34288362, PMID:34312566, PMID:34323218, PMID:34321666, PMID:34397094, PMID:34429473, PMID:34429379, PMID:34469721, PMID:34467850, PMID:34465863, PMID:34373460, PMID:34496246, PMID:34499028
Synonyms: ulp-4(gc54) II.
Alternate IDs: CGC_MC894
Notes: New Strain - Generated from papers flagged positive during the last month for data type afp_strain/other_strain.|"Suppresses hypoxia resistance of ddx-52(gc51). gc54 and gc55 are both missense alleles of ulp-4, but may behave somewhat differently. Reference: Itani OA, et al. Current Biology. 2021/01/11/ 2021;31(1):128-137.e5. PMID: 33157031."|"WBStrain mapped, WBPaper00060602 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00050290 Copy
http://www.wormbase.org/db/get?name=WBStrain00050297
Source Database: WormBase (WB)
Affected Genes: WBGene00022269(aatf-1)
Genomic Alteration: WBGene00022269(aatf-1)
Availability: available
Source References: PMID:32293562, PMID:32652074, PMID:32847964, PMID:33006972, PMID:32958476, PMID:32997655, PMID:33027250, PMID:33034119, PMID:33033228, PMID:33033182, PMID:33065011, PMID:33060131, PMID:33157031, PMID:33096249, PMID:33264285, PMID:33234550, PMID:33239401, PMID:33319748, PMID:33349622, PMID:33361147, PMID:33397797, PMID:33493646, PMID:33516872, PMID:33547005, PMID:33638604, PMID:33677541, PMID:33627403, PMID:33793670, PMID:33820857, PMID:33827942, PMID:33871019, PMID:33963848, PMID:34032213, PMID:34059684, PMID:34114562, PMID:34166401, PMID:34197450, PMID:34195824, PMID:34003969, PMID:34232959, PMID:34244496, PMID:34260587, PMID:34288362, PMID:34312566, PMID:34323218, PMID:34321666, PMID:34397094, PMID:34429473, PMID:34429379, PMID:34469721, PMID:34467850, PMID:34465863, PMID:34373460, PMID:34496246, PMID:34499028
Synonyms: aatf-1(gc63 gc64) I.
Alternate IDs: CGC_MC907
Notes: Gain-of-function mutation. Suppresses hypoxia resistance of ddx-52(gc51). gc63 gc64 occurred in the same mutagenesis; unclear which allele (or if both) is causing the gain of function. Reference: Itani OA, et al. Current Biology. 2021/01/11/ 2021;31(1):128-137.e5. PMID: 33157031.|"New Strain - Generated from papers flagged positive during the last month for data type afp_strain/other_strain."|"WBStrain mapped, WBPaper00060602 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00050297 Copy
http://www.wormbase.org/db/get?name=WBStrain00050587
Source Database: WormBase (WB)
Affected Genes: WBGene00003377(mls-2)
Genomic Alteration: WBGene00003377(mls-2)
Availability: available
Source References: PMID:35224463
Synonyms: mls-2(vy248[mNG::mls-2]) X.
Alternate IDs: CGC_IX4506
Notes: mNG tag inserted into endogenous mls-2 locus after the start codon using CRISPR/Cas9 engineering, producing a translational mNG::MLS-2 reporter protein. Derived by SEC excision of mls-2(vy247[mNG::SEC::mls-2 knock-in]) in parental strain. mNG::MLS-2 is detected in the nucleus of a few cells in embryos, and localizes to the nucleus of a subset of head cells and the M mesoblast in larvae and adults. Reference: Xiong R., et al. (2022). mNG-tagged mls-2 knock-in alleles in C. elegans. microPublication Biology. 10.17912/micropub.biology.000529.|"[2022-02-11T04:54:57.984Z WBPerson12028] New Strain: mls-2(vy248[mNG::mls-2 knock-in]) X; WBPaper00062471"
Proper citation: RRID:WB-STRAIN:WBStrain00050587 Copy
http://www.wormbase.org/db/get?name=WBStrain00040197
Source Database: WormBase (WB)
Availability: available
Synonyms: hjSi20 IV.
Alternate IDs: WB-STRAIN:VS21, CGC_VS21
Notes: hjSi20 [myo-2p::mCherry::unc-54 3'UTR]. Targeting construct derived from pCFJ90. Single copy transgene by MosSCI, inserted into cxTi10882.
Proper citation: RRID:WB-STRAIN:WBStrain00040197 Copy
http://www.wormbase.org/db/get?name=WBStrain00040199
Source Database: WormBase (WB)
Affected Genes: WBGene00011964(saeg-2)
Genomic Alteration: WBGene00011964(saeg-2)
Availability: available
Synonyms: saeg-2(hj9) III.
Alternate IDs: WB-STRAIN:VS23, CGC_VS23
Notes: Suppressor of activated EGL-4. Reference: Hao Y, et al. PLoS Genet. 2011 May;7(5):e1002065.
Proper citation: RRID:WB-STRAIN:WBStrain00040199 Copy
http://www.wormbase.org/db/get?name=WBStrain00040195
Source Database: WormBase (WB)
Affected Genes: WBGene00017123(maoc-1)
Genomic Alteration: WBGene00017123(maoc-1)
Availability: available
Synonyms: maoc-1(hj14) II.
Alternate IDs: WB-STRAIN:VS19, CGC_VS19
Notes: Reference: Zhang SO, et al. Proc Natl Acad Sci U S A. 2010;107(10):4640-5.
Proper citation: RRID:WB-STRAIN:WBStrain00040195 Copy
http://www.wormbase.org/db/get?name=WBStrain00040117
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwIs18.
Alternate IDs: WB-STRAIN:VL412, CGC_VL412
Notes: Made_by: N Martinez/M Ow|"wwIs18 [mir-79p::GFP + unc-119(+)]. Wild type."
Proper citation: RRID:WB-STRAIN:WBStrain00040117 Copy
http://www.wormbase.org/db/get?name=WBStrain00040115
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwEx31.
Alternate IDs: WB-STRAIN:VL397, CGC_VL397
Notes: Made_by: N Martinez/M Ow|"wwEx31 [mir-268p::GFP + unc-119(+)]. Maintain by picking WT."
Proper citation: RRID:WB-STRAIN:WBStrain00040115 Copy
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