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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00007104
Source Database: WormBase (WB)
Affected Genes: WBGene00006752(unc-13)
Genomic Alteration: WBGene00006752(unc-13)
Availability: available
Source References: PMID:36653384
Synonyms: unc-13(s69) I.
Alternate IDs: WB-STRAIN:EG9631, CGC_EG9631
Notes: Aldicarb resistant. This allele is a small exonic deletion that frameshifts exon 21, thus deleting the MUN domain of both long and short isoforms of unc-13. The reference allele e51 is R471-stop, affecting only UNC-13L. Derived by 2x outcross of BC168. Reference: Rose AM & Baillie DL. Genetics. 1980 Nov;96(3):639-48.|"Mutagen: Formaldehyde"
Proper citation: RRID:WB-STRAIN:WBStrain00007104 Copy
http://www.wormbase.org/db/get?name=WBStrain00007125
Source Database: WormBase (WB)
Affected Genes: WBGene00003030(lin-45)
Genomic Alteration: WBGene00003030(lin-45)
Availability: available
Source References: PMID:37643243
Synonyms: lin-45(dx19) IV/nT1 [unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:EJ521, CGC_EJ521
Notes: Heterozygotes are Unc and segregate Unc, non-Unc Steriles, larval lethals and dead eggs. dx19 is a strong lin-45 raf allele: dx19 homozygotes from dx19/+ heterozygous parents are 13% larval lethal and among the adults, 100% are Sterile and Vul.|"Supplementary_genotype lin-45(dx19)/nT1 [unc(n754) let] (IV;V)"
Proper citation: RRID:WB-STRAIN:WBStrain00007125 Copy
http://www.wormbase.org/db/get?name=WBStrain00007122
Source Database: WormBase (WB)
Affected Genes: WBGene00006765(unc-29)
Genomic Alteration: WBGene00006765(unc-29)
Availability: available
Source References: PMID:9383054
Synonyms: unc-29(e1072)/dxDf1 I.
Alternate IDs: WB-STRAIN:EJ275, CGC_EJ275
Notes: Heterozygotes are WT and segregate WT, Uncs and dead eggs.
Proper citation: RRID:WB-STRAIN:WBStrain00007122 Copy
http://www.wormbase.org/db/get?name=WBStrain00007120
Source Database: WormBase (WB)
Affected Genes: WBGene00003186(mek-2)|WBGene00006751(unc-11)
Genomic Alteration: WBGene00003186(mek-2), WBGene00006751(unc-11)
Availability: available
Source References: PMID:7671816
Synonyms: mek-2(q425) unc-11(e47) I; sDp2 (I;f).
Alternate IDs: WB-STRAIN:EJ238, CGC_EJ238
Notes: Animals with the duplication are WT. Animals which have lost the duplication are Unc, Sterile and Vul at all temperatures.
Proper citation: RRID:WB-STRAIN:WBStrain00007120 Copy
http://www.wormbase.org/db/get?name=WBStrain00007119
Source Database: WormBase (WB)
Affected Genes: WBGene00001651(gon-2)
Genomic Alteration: WBGene00001651(gon-2)
Availability: available
Source References: PMID:37624117, PMID:37729202, PMID:38446031
Synonyms: gon-2(q362) I.
Alternate IDs: WB-STRAIN:EJ26, CGC_EJ26
Notes: Starvation sensitive gonadogenesis defect.|"Supplementary_genotype gon-2(q362) I."|"WBStrain provided so WBPaper00061436 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00007119 Copy
http://www.wormbase.org/db/get?name=WBStrain00007257
Source Database: WormBase (WB)
Affected Genes: WBGene00004804(skn-1)
Genomic Alteration: WBGene00004804(skn-1)
Availability: available
Synonyms: skn-1(or12) IV/nT1 [unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:EU139, CGC_EU139
Notes: Heterozygotes are Unc and segregate Unc, WT which give only dead eggs, and dead eggs. Maintain by picking Unc. Received new stock 11/2002.|"Made_by: P Martin/B Bowerman"
Proper citation: RRID:WB-STRAIN:WBStrain00007257 Copy
http://www.wormbase.org/db/get?name=WBStrain00007255
Source Database: WormBase (WB)
Affected Genes: WBGene00004804(skn-1)|WBGene00006745(unc-5)
Genomic Alteration: WBGene00004804(skn-1), WBGene00006745(unc-5)
Availability: available
Source References: PMID:1547503
Synonyms: unc-5(e53) skn-1(zu67) IV/nT1 [let-?(m435)] (IV;V).
Alternate IDs: WB-STRAIN:EU84, CGC_EU84
Notes: Heterozygotes are WT and segregate WT, Uncs which give only dead eggs, and dead eggs.
Proper citation: RRID:WB-STRAIN:WBStrain00007255 Copy
http://www.wormbase.org/db/get?name=WBStrain00007251
Source Database: WormBase (WB)
Affected Genes: WBGene00004804(skn-1)
Genomic Alteration: WBGene00004804(skn-1)
Availability: available
Source References: PMID:32302543, PMID:33851304, PMID:36653384, PMID:37606250, PMID:38754743
Synonyms: skn-1(zu135) IV/nT1 [unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:EU31, CGC_EU31
Notes: Heterozygotes are Unc and segregate Unc, WT which give only dead eggs, and dead eggs. Maintain by picking Unc.|"Made_by: P Martin/B Bowerman"|"WBStrain mapped, WBPaper00059578 added based on AFP_Strain data."|"WBStrain provided so WBPaper00059477 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00061925 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00007251 Copy
http://www.wormbase.org/db/get?name=WBStrain00007250
Source Database: WormBase (WB)
Affected Genes: WBGene00001077(dpy-18)|WBGene00004027(pie-1)|WBGene00004804(skn-1)
Genomic Alteration: WBGene00001077(dpy-18), WBGene00004027(pie-1), WBGene00004804(skn-1)
Availability: available
Source References: PMID:1547503
Synonyms: dpy-18(e364) pie-1(zu154) III; skn-1(zu67)/nT1 [unc-?(n754) let-?] IV; +/nT1 V; eDp6 (III;f).
Alternate IDs: WB-STRAIN:EU16, CGC_EU16
Notes: Heterozygotes are Unc. Segregates Uncs (dpy-18 pie-1; skn-1/DnT1; eDp6), Dpy non-Uncs (dpy-18 pie-1; skn-1 with no Dp) which give only dead embryos, and DpyUncs (dpy-18 pie-1; skn-1/DnT1 with no Dp) which give only dead eggs, WT looking (dpy-18 pie-1; skn-1; eDp6) which give only dead embryos, and dead eggs.
Proper citation: RRID:WB-STRAIN:WBStrain00007250 Copy
http://www.wormbase.org/db/get?name=WBStrain00007249
Source Database: WormBase (WB)
Affected Genes: WBGene00004804(skn-1)
Genomic Alteration: WBGene00004804(skn-1)
Availability: available
Source References: PMID:1547503, PMID:31432005, PMID:31510078, PMID:33602504, PMID:33654835, PMID:37122724, PMID:37726773, PMID:38632209, PMID:39273603
Synonyms: skn-1(zu67) IV/nT1 [unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:EU1, CGC_EU1
Notes: Heterozygotes are Unc and segregate Unc, WT which give only dead eggs, and dead eggs. Maintain by picking Unc.|"Reference WBPaper00057259 added based on published strain data identified by Textpresso literature search."|"Reference WBPaper00058621 added based on published strain data identified by Textpresso literature search."|"Supplementary_genotype [skn-1(zu67) IV/nT1(IV;V)]"|"WBStrain mapped, WBPaper00061072 added based on AFP_Strain data."|"WBStrain mapped, WBPaper00061110 added based on AFP_Strain data."|"WBStrain provided so WBPaper00059477 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00007249 Copy
http://www.wormbase.org/db/get?name=WBStrain00007248
Source Database: WormBase (WB)
Affected Genes: WBGene00000517(cki-2)|WBGene00000912(daf-16)|WBGene00001609(glp-1)
Genomic Alteration: WBGene00000517(cki-2), WBGene00000912(daf-16), WBGene00001609(glp-1)
Availability: available
Synonyms: daf-16(mu86) I; cki-2(ok2105) II; glp-1(ar202) III.
Alternate IDs: WB-STRAIN:ET507, CGC_ET507
Notes: Temperature-sensitive. Maintain at 15C. Animals form germline tumors that prevent fertility at restrictive temerature (25C). This is the first strain reported to be used for the isolation of germ cells for in vitro culture. This strain allows germ cells to remain viable for longer periods than other tumorous mutant strains tested. Reference: Chaudhari SH, et al. Dev Cell. 2016 Jul 11;38(1):33-46.
Proper citation: RRID:WB-STRAIN:WBStrain00007248 Copy
http://www.wormbase.org/db/get?name=WBStrain00007247
Source Database: WormBase (WB)
Affected Genes: WBGene00001079(dpy-20)|WBGene00010890(ddb-1)
Genomic Alteration: WBGene00001079(dpy-20), WBGene00010890(ddb-1)
Availability: available
Synonyms: ddb-1(tm1769)/dpy-20(e2017) IV.
Alternate IDs: WB-STRAIN:ET263, CGC_ET263
Notes: Heterozygotes are WT and segregate WT, Dpy and ddb-1 homozygotes, which arrest as L2-stage larvae (approx. 15%) or become sterile adults with protruding vulva (approx. 85%).|"Made_by: S. Mitani/E. Kipreos"|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00007247 Copy
http://www.wormbase.org/db/get?name=WBStrain00007268
Source Database: WormBase (WB)
Affected Genes: WBGene00001609(glp-1)|WBGene00003395(mom-2)
Genomic Alteration: WBGene00001609(glp-1), WBGene00003395(mom-2)
Availability: available
Synonyms: glp-1(e2141) III; mom-2(or42) IV/nT1 [unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:EU367, CGC_EU367
Notes: Maintain at 15C. Animals are Unc.
Proper citation: RRID:WB-STRAIN:WBStrain00007268 Copy
http://www.wormbase.org/db/get?name=WBStrain00007301
Source Database: WormBase (WB)
Affected Genes: WBGene00006974(zen-4)
Genomic Alteration: WBGene00006974(zen-4)
Availability: available
Synonyms: zen-4(or153) IV.
Alternate IDs: WB-STRAIN:EU716, CGC_EU716
Notes: Temperature-sensitive, embryonic-lethal mutant that lacks a central spindle during early embryonic mitosis and exhibits a late cytokinesis defect (cleavage furrows regress after ingressing in nearly to the center of dividing embryonic cells). About 100% of embryos produced by homozygous mothers hatch at 15C; 0% hatch at 26C. ZEN-4 = vertebrate MKLP1 kinesin. There are two mis-sense mutations present in zen-4(or153). One is a D520N (GAC to AAC) and the other is D735N (GAT to AAT). Whether one or both is responsible for the phenotype is not know. Maintain at 15C. Shift L4s to 26 overnight to observe mutant phenotype on embyros produced by adults.
Proper citation: RRID:WB-STRAIN:WBStrain00007301 Copy
http://www.wormbase.org/db/get?name=WBStrain00007266
Source Database: WormBase (WB)
Affected Genes: WBGene00002368(let-99)
Genomic Alteration: WBGene00002368(let-99)
Availability: available
Synonyms: let-99(or81) IV/nT1 [unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:EU363, CGC_EU363
Notes: Heterozygotes are Unc.
Proper citation: RRID:WB-STRAIN:WBStrain00007266 Copy
http://www.wormbase.org/db/get?name=WBStrain00007264
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00001067(dpy-5)|WBGene00003397(mom-5)
Genomic Alteration: WBGene00000254(bli-4), WBGene00001067(dpy-5), WBGene00003397(mom-5)
Availability: available
Source References: PMID:9288749
Synonyms: dpy-5(e61) mom-5(or57)/hT2 I; +/hT2 [bli-4(e937) let-?(h661)] III.
Alternate IDs: WB-STRAIN:EU311, CGC_EU311
Notes: Heterozygotes are WT and segregate WT, Dpys and dead eggs. Dpys give only embryonic lethals which lack endoderm and make excess mesoderm. or57 is a recessive maternal-effect lethal.|"mut-2 background"
Proper citation: RRID:WB-STRAIN:WBStrain00007264 Copy
http://www.wormbase.org/db/get?name=WBStrain00007263
Source Database: WormBase (WB)
Affected Genes: WBGene00001068(dpy-6)|WBGene00003056(lon-2)|WBGene00003394(mom-1)
Genomic Alteration: WBGene00001068(dpy-6), WBGene00003056(lon-2), WBGene00003394(mom-1)
Availability: available
Synonyms: +/szT1 [lon-2(e678)] I; mom-1(or10) dpy-6(e14)/szT1 X.
Alternate IDs: WB-STRAIN:EU308, CGC_EU308
Notes: Heterozygotes are WT and segregate WT, Lon males, lots of dead eggs, and Dpys. The Dpys should give all dead embryos at all temperatures. Approximately 60% of these dead embryos make excess mesoderm at the expense of endoderm, due to an E to MS fate transformation. Embryonic lethality is 100% penetrant for or10.
Proper citation: RRID:WB-STRAIN:WBStrain00007263 Copy
http://www.wormbase.org/db/get?name=WBStrain00007262
Source Database: WormBase (WB)
Affected Genes: WBGene00001068(dpy-6)|WBGene00003056(lon-2)|WBGene00003394(mom-1)
Genomic Alteration: WBGene00001068(dpy-6), WBGene00003056(lon-2), WBGene00003394(mom-1)
Availability: available
Synonyms: +/szT1 [lon-2(e678)] I; mom-1(or46) dpy-6(e14)/szT1 X.
Alternate IDs: WB-STRAIN:EU307, CGC_EU307
Notes: Heterozygotes are WT and segregate WT, Lon males, lots of dead eggs, and Dpys. The Dpys should give all dead embryos at all temperatures. Approximately 60% of these dead embryos make excess mesoderm at the expense of endoderm, due to an E to MS fate transformation. Embryonic lethality is 100% penetrant for or46.
Proper citation: RRID:WB-STRAIN:WBStrain00007262 Copy
http://www.wormbase.org/db/get?name=WBStrain00007261
Source Database: WormBase (WB)
Affected Genes: WBGene00000168(apx-1)
Genomic Alteration: WBGene00000168(apx-1)
Availability: available
Synonyms: apx-1(or22) V/nT1 [unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:EU176, CGC_EU176
Notes: Heterozygotes are Unc and segregate Unc and wild type animals which give only dead progeny.
Proper citation: RRID:WB-STRAIN:WBStrain00007261 Copy
http://www.wormbase.org/db/get?name=WBStrain00007279
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00003396(mom-4)|WBGene00006752(unc-13)
Genomic Alteration: WBGene00000254(bli-4), WBGene00003396(mom-4), WBGene00006752(unc-13)
Availability: available
Source References: PMID:9288749
Synonyms: unc-13(e1091) mom-4(or39)/hT2 I; +/hT2 [bli-4(e937) let-?(h661)] III.
Alternate IDs: WB-STRAIN:EU446, CGC_EU446
Notes: Heterozygotes are WT. Segregates Uncs which give only embryonic lethals which lack gut and make excess mesoderm (E adopts an MS-like fate). or39 is a recessive maternal-effect embryonic lethal.
Proper citation: RRID:WB-STRAIN:WBStrain00007279 Copy
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