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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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SD-Sncaem1Sage Resource Report Resource Website |
RRID:RGD_13782164 | Rattus norvegicus | This model contains a deletion of the endogenous rat SNCA gene, encoding the alpha-synuclein protein. This model was generated using the CRISPR/Cas9 genome targeting strategy. Horizon Discovery | 13782164 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2018-08-24) | 13782164 | RGD | 2026-09-26 02:42:10 | 0 | |||||
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SD-Sncatm1(SNCA*)Sage Resource Report Resource Website |
RRID:RGD_13782163 | Rattus norvegicus | This model contains a knockin of the A53T-mutated SNCA gene deeming the rat SNCA gene non-functional. The knockin contains humanized amino acids for the region spanning amino acids 53-122. The resulting model expresses a humanized A53T alpha-synuclein protein without endogenous rat alpha-synuclein. Horizon Discovery | 13782163 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2018-08-24) | 13782163 | RGD | 2026-09-26 02:42:10 | 0 | |||||
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SD-Abcb1aem1Sage -/- Resource Report Resource Website |
RRID:RGD_12904057 | Rattus norvegicus | This ZFN model contains biallelic 20 bp deletion within Abcba1 gene. Animals exhibit increased oral bioavailability of P-gp-specific substrates. The homozygous knockout rats display total loss of protein via Western blot. Horizon Discovery | 12904057 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-16) | 12904057 | RGD | 2026-09-26 02:42:10 | 0 | |||||
|
FHH-Muc1em1Mcwi Resource Report Resource Website |
RRID:RGD_13800825 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 2 of rat Muc1 gene in the FHH/EurMcwi embryos. Contact MCW rat distribution at [email protected] | 13800825 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-10-18) | 13800825 | RGD | 2026-09-26 02:42:10 | 0 | |||||
|
SD-(Abcb1a- Abcb1b)em1Sage Resource Report Resource Website |
RRID:RGD_12904059 | Rattus norvegicus | This model carries knockout of Abcb1a and Abcb1b. Horizon Discovery | 12904059 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-16) | 12904059 | RGD | 2026-09-26 02:42:10 | 0 | |||||
|
BN-Crb1m1 Resource Report Resource Website |
RRID:RGD_13451132 | Rattus norvegicus | This Brown Norway from Janvier rat strain spontaneously develops progressive focal retinal layer disorganization, loss of photoreceptors, cystic cavitation, and RMG abnormalities associated with early retinal vascular telangiectasia and late stage subretinal neovascularization. This phenotype bears reminiscent of human Macular telangiectasia 2. A deletion insertion mutation in exon 6 of the rat crb1 was identified to be responsible for this retinal phenotype. | 13451132 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13451132 | RGD | 2026-09-26 02:42:10 | 0 | |||||
|
LEW-Chrnb4em5Mcwi Resource Report Resource Website |
RRID:RGD_13207488 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Chrnb4 gene of LEW/NCrl rat embryos. The resulting mutation is a 4-bp deletion of exon 4 in the Chrnb4 gene. Contact MCW rat distribution at [email protected] | 13207488 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13207488 | RGD | 2026-09-26 02:42:09 | 0 | |||||
|
SD-Nr1i2em1Sage Nr1i3em1Sage Ahrem1Sage Resource Report Resource Website 1+ mentions |
RRID:RGD_12903272 | Rattus norvegicus | This model contains three knockout genes, the 20-bp deletion within rat Nr1i2, the ZFN-induced 10-bp deletion within rat Nr1i3 gene and the 760-bp deletion in the rat Ahr gene. Horizon Discovery | 12903272 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2017-05-10) | 12903272 | RGD | 2026-09-26 02:42:10 | 1 | |||||
|
SS-Kcnq1em5Mcwi Resource Report Resource Website |
RRID:RGD_13800810 | Rattus norvegicus | CRISPR/Cas9 system and the single-stranded oligodeoxynucleotide (ssODN ) were combined to introduce the R231H mutation in the Kcnq1 gene of SS/JrHsdMcwi rat embryos. Contact MCW rat distribution at [email protected] | 13800810 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo; Cryopreserved Sperm (as of 2018-10-18) | 13800810 | RGD | 2026-09-26 02:42:10 | 0 | |||||
|
SD-Trpv1em1Sage+/+ Resource Report Resource Website |
RRID:RGD_13792705 | Rattus norvegicus | These ZFN mutant rats were produced by injecting zinc finger nuclease targeting exon 13 of rat Trpv1 into Sprague Dawley embryos. A 2-bp (CA) frameshift deletion in exon 13 was created ( SD-Trpv1em1Sage-/-). This wild type mutant is the wild type offspring from the cross of heterozygous mutants. | 13792705 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13792705 | RGD | 2026-09-26 02:42:10 | 0 | |||||
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SD-Trpv1em1Sage-/- Resource Report Resource Website |
RRID:RGD_13792701 | Rattus norvegicus | These ZFN mutant rats were produced by injecting zinc finger nuclease targeting exon 13 of rat Trpv1 into Sprague Dawley embryos. A 2-bp (CA) frameshift deletion in exon 13 was created. Homozygous knockout rats exhibit complete loss of Trpv1 protein. Horizon Discovery | 13792701 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2018-09-21) | 13792701 | RGD | 2026-09-26 02:42:10 | 0 | |||||
|
SD-Lamp2em1 Resource Report Resource Website 1+ mentions |
RRID:RGD_13703119 | Rattus norvegicus | This strain was produced by injecting TALEN targeting exon 2 of rat Lamp2 into SD embryos. The resulting mutation is a 2-bp deletion and results in knockout of Lamp2 protein in Lamp2 y/- male. | 13703119 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13703119 | RGD | 2026-09-26 02:42:10 | 1 | |||||
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SD-Nr1i2em1Sage Nr1i3em1Sage Resource Report Resource Website |
RRID:RGD_12903270 | Rattus norvegicus | This model contains two knockout genes, the 20-bp deletion within rat Nr1i2 and the ZFN-induced 10-bp deletion within rat Nr1i3 gene. Horizon Discovery | 12903270 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-10) | 12903270 | RGD | 2026-09-26 02:42:09 | 0 | |||||
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SHRSP-Spp1em2Mcwi Resource Report Resource Website |
RRID:RGD_13792813 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Spp1 gene of SHRSP/A3NCrl rat embryos. The resulting mutation is a 11-bp deletion in Exon 3 of the Spp1 gene. Contact MCW rat distribution at [email protected] | 13792813 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-10-01) | 13792813 | RGD | 2026-09-26 02:42:10 | 0 | |||||
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FPL/Iet Resource Report Resource Website |
RRID:RGD_13464329 | Rattus norvegicus | , FPL | This spontaneous mutant strain wa found in a colony of Jcl:Wistar strain at the Institute of Environmental Toxicology in 1978: 3 rats out of 13 rats showed fused right pulmonary lobes with reduction deformity of middle pulmonary lobes. These rats also had the syndactylism or paten tof the eyelid. It was difficult to maintain this strain in homozygous condition, mating system has been changed to sib mating between heterozygous rats. National BioResource Project for the Rat in Japan | 13464329 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2023-09-28) | 13464329 | RGD | 2026-09-26 02:42:09 | 0 | ||||
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WKY-Tph1em3Mcwi Resource Report Resource Website |
RRID:RGD_13208231 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Tph1 gene of WKY/NCrl rat embryos. The resulting mutation is a 1-bp insertion in the exon 4 of the Tph1 gene. Contact MCW rat distribution at [email protected] | 13208231 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13208231 | RGD | 2026-09-26 02:42:10 | 0 | |||||
|
SS-Tlr4em1Mcwi Resource Report Resource Website |
RRID:RGD_13793372 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Tlr4 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 1-bp deletion in exon 2. Contact MCW rat distribution at [email protected] | 13793372 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13793372 | RGD | 2026-09-26 02:42:10 | 0 | |||||
|
T2DN-F2rem1Mcwi Resource Report Resource Website |
RRID:RGD_13799350 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 1 of F2r gene in the T2DN/Mcwi embryos. Contact MCW rat distribution at [email protected] | 13799350 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-10-10) | 13799350 | RGD | 2026-09-26 02:42:10 | 0 | |||||
|
SS-P2ry2em7Mcwi Resource Report Resource Website |
RRID:RGD_13800871 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the P2ry2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 115-bp deletion in exon 3 in the P2ry2 gene. Contact MCW rat distribution at [email protected] | 13800871 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13800871 | RGD | 2026-09-26 02:42:10 | 0 | |||||
|
SS-Prltm1(PRL)Mcwi Resource Report Resource Website |
RRID:RGD_13800875 | Rattus norvegicus | CRISPR/Cas9 and plasmid donor containing floxed human prolactin cDNA were used to insert the human cDNA into the start coden of rat prolactin gene Contact MCW rat distribution at [email protected] | 13800875 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13800875 | RGD | 2026-09-26 02:42:10 | 0 |
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