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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00040571
Source Database: WormBase (WB)
Affected Genes: WBGene00003030(lin-45)|WBGene00006761(unc-24)
Genomic Alteration: WBGene00003030(lin-45), WBGene00006761(unc-24)
Availability: available
Synonyms: lin-45(n2520) unc-24(e138) IV.
Alternate IDs: WB-STRAIN:WU51, CGC_WU51
Notes: Weak severity of lin-45 raf allele: WT viability, vulval induction and fertility but effectively suppresses the let-60(n1046gf) Muv phenotype. Unc.
Proper citation: RRID:WB-STRAIN:WBStrain00040571 Copy
http://www.wormbase.org/db/get?name=WBStrain00040573
Source Database: WormBase (WB)
Affected Genes: WBGene00001079(dpy-20)|WBGene00003030(lin-45)|WBGene00006745(unc-5)|WBGene00006761(unc-24)
Genomic Alteration: WBGene00001079(dpy-20), WBGene00003030(lin-45), WBGene00006745(unc-5), WBGene00006761(unc-24)
Availability: available
Synonyms: lin-45(n2510) unc-24(e138)/unc-5(e53) dpy-20(e1282) IV.
Alternate IDs: WB-STRAIN:WU57, CGC_WU57
Notes: Heterozygotes are non-Unc and segregate non-Unc, Sterile Unc, and Dpy Unc. n2510 is a strong lin-45 raf allele: 100% of homozygotes are Sterile and Vul (no discernable vulva) or larval lethal.
Proper citation: RRID:WB-STRAIN:WBStrain00040573 Copy
http://www.wormbase.org/db/get?name=WBStrain00040572
Source Database: WormBase (WB)
Affected Genes: WBGene00003030(lin-45)|WBGene00006761(unc-24)
Genomic Alteration: WBGene00003030(lin-45), WBGene00006761(unc-24)
Availability: available
Synonyms: lin-45(n1925) unc-24(e138) IV.
Alternate IDs: WB-STRAIN:WU53, CGC_WU53
Notes: Weak lin-45 raf allele: essentially WT viability, vulval induction and fertility but effectively suppresses the let-60(n1046gf) Muv phenotype. Unc.
Proper citation: RRID:WB-STRAIN:WBStrain00040572 Copy
http://www.wormbase.org/db/get?name=WBStrain00040578
Source Database: WormBase (WB)
Affected Genes: WBGene00020847(cgr-1)
Genomic Alteration: WBGene00020847(cgr-1)
Availability: available
Synonyms: cgr-1(n2528) X.
Alternate IDs: WB-STRAIN:WU321, CGC_WU321
Notes: Slow growing at 20C. About 50% larval lethality at 15C. Maintain at 20C.
Proper citation: RRID:WB-STRAIN:WBStrain00040578 Copy
http://www.wormbase.org/db/get?name=WBStrain00040575
Source Database: WormBase (WB)
Affected Genes: WBGene00003030(lin-45)|WBGene00006761(unc-24)
Genomic Alteration: WBGene00003030(lin-45), WBGene00006761(unc-24)
Availability: available
Synonyms: lin-45(n1924) unc-24(e138) IV.
Alternate IDs: WB-STRAIN:WU144, CGC_WU144
Notes: Weak lin-45 raf allele: 5% larval lethal. Otherwise, essentially WT vulval induction and fertility. n1924 effectively suppresses the let-60(n1046gf) Muv phenotype. Unc.
Proper citation: RRID:WB-STRAIN:WBStrain00040575 Copy
http://www.wormbase.org/db/get?name=WBStrain00040577
Source Database: WormBase (WB)
Affected Genes: WBGene00000393(cdf-1)
Genomic Alteration: WBGene00000393(cdf-1)
Availability: available
Source References: PMID:10511554
Synonyms: cdf-1(n2527) X.
Alternate IDs: WB-STRAIN:WU209, CGC_WU209
Notes: Severe loss of function/null. Weak vulvaless phenotype (subtle defect in vulval cell lineages). Nonsense change of codon 186 of the predicted ORF C15B12.7. See also WBPaper00005255.
Proper citation: RRID:WB-STRAIN:WBStrain00040577 Copy
http://www.wormbase.org/db/get?name=WBStrain00040576
Source Database: WormBase (WB)
Affected Genes: WBGene00001074(dpy-13)|WBGene00002990(lin-1)
Genomic Alteration: WBGene00001074(dpy-13), WBGene00002990(lin-1)
Availability: available
Source References: PMID:9691039
Synonyms: lin-1(n2515) dpy-13(e184) IV.
Alternate IDs: WB-STRAIN:WU156, CGC_WU156
Notes: n2515 suppresses the let-60(gf) Muv phenotype. Isolation of lin-1 causes no significant vulval defect; it is a missense mutation that changes Proline 384 to Leucine. dpy-13 is a linked marker.
Proper citation: RRID:WB-STRAIN:WBStrain00040576 Copy
http://www.wormbase.org/db/get?name=WBStrain00040509
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: sprSi6 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:WRM6, CGC_WRM6
Notes: Made_by: Brian Farley|"sprSi6 [mex-5p::MODC PEST::GFP::H2B::glp-1 (deltaGBM UtoC) 3'UTR + Cbr-unc-119(+)] II. Reference: Farley BM, Ryder SP. Mol Biol Cell. 2012 Oct 3."
Proper citation: RRID:WB-STRAIN:WBStrain00040509 Copy
http://www.wormbase.org/db/get?name=WBStrain00040505
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: sprSi1 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:WRM1, CGC_WRM1
Notes: Made_by: John Pagano|"sprSi1 [pie-1p::GFP::histone-H2B::nos-2(MRE mut) 3'UTR + Cbr-unc-119(+)] II. Nuclear GFP fluorescence in germline progenitor cells in early embryos. Reference: Pagano JM, et al. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20252-7."
Proper citation: RRID:WB-STRAIN:WBStrain00040505 Copy
http://www.wormbase.org/db/get?name=WBStrain00040507
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: sprSi3 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:WRM3, CGC_WRM3
Notes: Made_by: John Pagano|"sprSi3 [mex-5p::GFP::histone-H2B::glp-1 3'UTR + Cbr-unc-119(+)] II. Fluorescence in the distal germline and in early embryos. Reference: Pagano JM, et al. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20252-7."
Proper citation: RRID:WB-STRAIN:WBStrain00040507 Copy
http://www.wormbase.org/db/get?name=WBStrain00040582
Source Database: WormBase (WB)
Affected Genes: WBGene00009813(haly-1)
Genomic Alteration: WBGene00009813(haly-1)
Availability: available
Synonyms: haly-1(am132) X.
Alternate IDs: WB-STRAIN:WU970, CGC_WU970
Notes: Made_by: Janelle Bruinsm|"Resistance to excess dietary zinc and nickel observed on noble agar minimal media with supplemental zinc or nickel; elevated levels of histidine observed in C. elegans on minimal media. Reference: Murphy JT, et al. PLoS Genet. 2011 Mar;7(3):e1002013."
Proper citation: RRID:WB-STRAIN:WBStrain00040582 Copy
http://www.wormbase.org/db/get?name=WBStrain00040584
Source Database: WormBase (WB)
Affected Genes: WBGene00020719(natc-1)
Genomic Alteration: WBGene00020719(natc-1)
Availability: available
Synonyms: natc-1(am134) V.
Alternate IDs: WB-STRAIN:WU982, CGC_WU982
Notes: natc-1(am134) mutant animals are resistant to excess dietary zinc. References: Warnhoff K, et al. PLoS Genet. 2014 Oct 16;10(10):e1004703. Bruinsma JJ, et al. Genetics. 2008 Jun;179(2):811-28.
Proper citation: RRID:WB-STRAIN:WBStrain00040584 Copy
http://www.wormbase.org/db/get?name=WBStrain00040583
Source Database: WormBase (WB)
Affected Genes: WBGene00009813(haly-1)
Genomic Alteration: WBGene00009813(haly-1)
Availability: available
Synonyms: haly-1(am130) X.
Alternate IDs: WB-STRAIN:WU971, CGC_WU971
Notes: Made_by: Janelle Bruinsm|"Resistance to excess dietary zinc and nickel observed on noble agar minimal media with supplemental zinc or nickel; elevated levels of histidine observed in C. elegans on minimal media. Reference: Murphy JT, et al. PLoS Genet. 2011 Mar;7(3):e1002013."
Proper citation: RRID:WB-STRAIN:WBStrain00040583 Copy
http://www.wormbase.org/db/get?name=WBStrain00040502
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:33820969, PMID:38564369
Synonyms: Caenorhabditis elegans wild isolate.
Alternate IDs: WB-STRAIN:WN2064
Notes: Added Wild_Isolate tag as Isolation information is available suggesting that they were sampled from the wild.
Proper citation: RRID:WB-STRAIN:WBStrain00040502 Copy
http://www.wormbase.org/db/get?name=WBStrain00040589
Source Database: WormBase (WB)
Affected Genes: WBGene00001119(dyf-3)
Genomic Alteration: WBGene00001119(dyf-3)
Availability: available
Synonyms: dyf-3(og22) IV.
Alternate IDs: WB-STRAIN:WX737, CGC_WX737
Notes: Dyf (DiI), chemotaxis defective towards IAA. Preliminary results show increased longevity.
Proper citation: RRID:WB-STRAIN:WBStrain00040589 Copy
http://www.wormbase.org/db/get?name=WBStrain00040504
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:33820969, PMID:38564369
Synonyms: Caenorhabditis elegans wild isolate.
Alternate IDs: WB-STRAIN:WN2066
Notes: Added Wild_Isolate tag as Isolation information is available suggesting that they were sampled from the wild.
Proper citation: RRID:WB-STRAIN:WBStrain00040504 Copy
http://www.wormbase.org/db/get?name=WBStrain00040503
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:33820969
Synonyms: Caenorhabditis elegans wild isolate.
Alternate IDs: WB-STRAIN:WN2065
Notes: Added Wild_Isolate tag as Isolation information is available suggesting that they were sampled from the wild.
Proper citation: RRID:WB-STRAIN:WBStrain00040503 Copy
http://www.wormbase.org/db/get?name=WBStrain00040588
Source Database: WormBase (WB)
Affected Genes: WBGene00013976(hizr-1)
Genomic Alteration: WBGene00013976(hizr-1)
Availability: available
Synonyms: hizr-1(am285) X.
Alternate IDs: WB-STRAIN:WU1563, CGC_WU1563
Notes: Gain-of-function allele: modified ligand binding domain constitutively binds HZA element. High zinc transcriptional activation - constitutive (Zad-c). [NOTE: this strain was previously described as hizr-1(am286); the correct allele name hizr-1(am285).] Reference: Warnhoff K, et al. PLoS Biol. 2017 Jan 17;15(1):e2000094.
Proper citation: RRID:WB-STRAIN:WBStrain00040588 Copy
http://www.wormbase.org/db/get?name=WBStrain00040587
Source Database: WormBase (WB)
Affected Genes: WBGene00013976(hizr-1)
Genomic Alteration: WBGene00013976(hizr-1)
Availability: available
Synonyms: hizr-1(am286) X.
Alternate IDs: WB-STRAIN:WU1500, CGC_WU1500
Notes: High zinc transcriptional activation - deficient (Zad-d). Avoid high zinc concentrations. [NOTE: this strain was previously described as hizr-1(am285); the correct allele name hizr-1(am286).] Reference: Warnhoff K, et al. PLoS Biol. 2017 Jan 17;15(1):e2000094.
Proper citation: RRID:WB-STRAIN:WBStrain00040587 Copy
http://www.wormbase.org/db/get?name=WBStrain00040550
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; opEx1556.
Alternate IDs: WB-STRAIN:WS6608, CGC_WS6608
Notes: opEx1556 [tyr-3p::tyr-3::GFP::tyr-3 3' UTR + unc-119(+)]. Pick non-Unc GFP+ to maintain. This strain replaced WS4623 opIs271, which was apparently not an integrated line.
Proper citation: RRID:WB-STRAIN:WBStrain00040550 Copy
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