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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.taconic.com/mouse-model/nod-scid
Source Database: Taconic Biosciences
Affected Genes: protein kinase; DNA activated; catalytic polypeptide
Genomic Alteration: severe combined immunodeficiency
Availability: live
Synonyms: NODMrkBomTac.Cg-Prkdc
Notes: gene symbol note: protein kinase; DNA activated; catalytic polypeptide; mutant strain|inbred strain: Prkdc
Proper citation: RRID:IMSR_TAC:NODSC Copy
http://www.taconic.com/mouse-model/nmri
Source Database: Taconic Biosciences
Availability: live
Notes: gene symbol note: ; noninbred stock:
Proper citation: RRID:IMSR_TAC:NMRI Copy
https://www.taconic.com/mouse-model/hunog-exl
Source Database: Taconic Biosciences
Availability: live
Notes: gene symbol note: ; mutant strain:
Proper citation: RRID:IMSR_TAC:HSCFTL-13395 Copy
https://www.taconic.com/mouse-model/hunog
Source Database: Taconic Biosciences
Availability: live
Notes: gene symbol note: ; mutant strain:
Proper citation: RRID:IMSR_TAC:HSCFTL-NOG Copy
https://www.taconic.com/transgenic-mouse-model/mdr1a
Source Database: Taconic Biosciences
Affected Genes: |ATP-binding cassette; sub-family B member 1A
Genomic Alteration: |targeted mutation 1; Piet Borst
Availability: live
Synonyms: FVB.129P2-Abcb1a
Notes: gene symbol note: |ATP-binding cassette; sub-family B member 1A; mutant strain|congenic strain: |Abcb1a
Proper citation: RRID:IMSR_TAC:MDR1A Copy
http://www.cfmice.org/cf-mouse-strains.html
Source Database: Cystic Fibrosis Mouse Model Core
Affected Genes: cystic fibrosis transmembrane conductance regulator
Genomic Alteration: endonuclease-mediated mutation 3; Case Western Reserve University
Availability: live
Notes: gene symbol note: cystic fibrosis transmembrane conductance regulator; coisogenic strain: Cftr
Proper citation: RRID:IMSR_CWR:CGX Copy
https://www.taconic.com/transgenic-mouse-model/apob100
Source Database: Taconic Biosciences
Genomic Alteration: transgene insertion 1102; Stephen G Young
Availability: live
Synonyms: ApoB100 MICROINJECTED - C57BL/6 Background. B6.Cg-Tg(APOB)1102Sgy/Tac
Notes: gene symbol note: ; mutant strain|congenic strain:
Proper citation: RRID:IMSR_TAC:1004 Copy
https://www.taconic.com/rat-model/lrrk2-g2019s
Source Database: Taconic Biosciences
Availability: live
Notes: gene symbol note: ; mutant strain:
Proper citation: RRID:IMSR_TAC:10681 Copy
https://www.taconic.com/transgenic-mouse-model/oatp1a1b-cluster-knockout-mouse
Source Database: Taconic Biosciences
Availability: live
Notes: gene symbol note: ; mutant strain:
Proper citation: RRID:IMSR_TAC:10707 Copy
http://www.cfmice.org/cf-mouse-strains.html
Source Database: Cystic Fibrosis Mouse Model Core
Affected Genes: cystic fibrosis transmembrane conductance regulator
Genomic Alteration: targeted mutation 1; Case Western Reserve University
Availability: live
Notes: gene symbol note: cystic fibrosis transmembrane conductance regulator; congenic strain: Cftr
Proper citation: RRID:IMSR_CWR:CFC Copy
The record is no longer available at this source.
Source Database: NSRRC, National Swine Resource and Research Center (NSRRC)
Genetic Background: domestic
Affected Genes: FANCA
Notes: KO of FANCA Exon 4 via zygote injection of the CRISPR Cas-9 system.
Proper citation: RRID:NSRRC_0075 Copy
https://www.jax.org/strain/004133
Source Database: JAX Mice and Services
Affected Genes: amyloid beta precursor protein
Genomic Alteration: targeted mutation 1; David R Borchelt
Availability: live
Notes: gene symbol note: amyloid beta precursor protein; mutant strain|congenic strain: App
Proper citation: RRID:IMSR_JAX:004133 Copy
https://www.jax.org/strain/004297
Source Database: JAX Mice and Services
Affected Genes: phosphodiesterase 6B; cGMP; rod receptor; beta polypeptide
Genomic Alteration: retinal degeneration 10
Availability: live
Notes: gene symbol note: phosphodiesterase 6B; cGMP; rod receptor; beta polypeptide; mutant strain|congenic strain: Pde6b
Proper citation: RRID:IMSR_JAX:004297 Copy
https://www.jax.org/strain/004424
Source Database: JAX Mice and Services
Affected Genes: coagulation factor VIII
Genomic Alteration: targeted mutation 1; Haig H Kazazian Jr
Availability: live
Synonyms: B6;129S4-F8
Notes: gene symbol note: coagulation factor VIII; mutant stock: F8
Proper citation: RRID:IMSR_JAX:004424 Copy
https://www.jax.org/strain/004353
Source Database: JAX Mice and Services
Affected Genes: ubiquitin C||transgene insertion 30; Brian Schaefer
Genomic Alteration: transgene insertion 30; Brian Schaefer
Availability: live
Synonyms: B6-GFP. B6.GFP. B6-EGFP
Notes: gene symbol note: ubiquitin C||transgene insertion 30; Brian Schaefer; coisogenic strain|mutant strain: UBC||Tg(UBC-GFP)30Scha
Proper citation: RRID:IMSR_JAX:004353 Copy
https://www.jax.org/strain/004479
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 83; Virginia M-Y Lee|prion protein|synuclein alpha
Genomic Alteration: transgene insertion 83; Virginia M-Y Lee
Availability: live
Synonyms: M83. B6;C3H-Tg(SNCA)83Vle/J
Notes: gene symbol note: transgene insertion 83; Virginia M-Y Lee|prion protein|synuclein alpha; mutant stock: Tg(Prnp-SNCA*A53T)83Vle|Prnp|SNCA
Proper citation: RRID:IMSR_JAX:004479 Copy
https://www.jax.org/strain/004804
Source Database: JAX Mice and Services
Affected Genes: histocompatibility-2; MHC|histocompatibility 2; T region locus 18
Genomic Alteration: k2 variant|a variant
Availability: live
Synonyms: B10.BR-H2
Notes: gene symbol note: histocompatibility-2; MHC|histocompatibility 2; T region locus 18; mutant strain|major histocompatibility congenic|congenic strain: H2|H2-T18
Proper citation: RRID:IMSR_JAX:004804 Copy
https://www.jax.org/strain/004682
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 5; Andrew P McMahon|Cre recombinase and estrogen receptor 1 fusion gene|actin; beta
Genomic Alteration: transgene insertion 5; Andrew P McMahon
Availability: live
Synonyms: B6.Cg-Tg(cre/Esr1)5Amc/J. B6.Cg-Tg(CAG-cre/Esr1)5Amc/J
Notes: gene symbol note: transgene insertion 5; Andrew P McMahon|Cre recombinase and estrogen receptor 1 fusion gene|actin; beta; mutant strain|congenic strain: Tg(CAG-cre/Esr1*)5Amc|cre/Esr1|ACTB
Proper citation: RRID:IMSR_JAX:004682 Copy
https://www.jax.org/strain/004754
Source Database: JAX Mice and Services
Affected Genes: interleukin 1 receptor antagonist
Genomic Alteration: targeted mutation 1; David Hirsh
Availability: live
Notes: gene symbol note: interleukin 1 receptor antagonist; mutant strain|congenic strain: Il1rn
Proper citation: RRID:IMSR_JAX:004754 Copy
https://www.jax.org/strain/004584
Source Database: JAX Mice and Services
Affected Genes: peroxisome proliferator activated receptor gamma
Genomic Alteration: targeted mutation 2; Ronald M Evans
Availability: live
Notes: gene symbol note: peroxisome proliferator activated receptor gamma; mutant strain|congenic strain: Pparg
Proper citation: RRID:IMSR_JAX:004584 Copy
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