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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

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Organism Name Proper Citation Species Synonyms Notes Phenotype Affected Gene Genomic Alteration Catalog Number Background Database Database Abbreviation Availability Source References Alternate IDs Authority Record Last Update Mentions Count
LH-Chr 17LN-C17h6orf52em2Mcwi
 
Resource Report
Resource Website
RRID:RGD_13800877 Rattus norvegicus CRISPR/Cas9 system was used to introduce a net 10-bp insertion in exon 2 of rat C17h6orf52. 13800877 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2026-01-14) 13800877 RGD 2026-09-26 02:42:10 0
SS-Avpr2em5Mcwi
 
Resource Report
Resource Website
RRID:RGD_13793378 Rattus norvegicus CRISPR/Cas9 system was used to introduce a mutation in the Avpr2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 9-bp deletion in exon 2. Contact MCW rat distribution at [email protected] 13793378 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2018-10-03) 13793378 RGD 2026-09-26 02:42:10 0
DA-Tph1em4Mcwi
 
Resource Report
Resource Website
RRID:RGD_13793374 Rattus norvegicus CRISPR/Cas9 system was used to introduce a mutation in the Tph1 gene of DA/MolTac rat embryos. The resulting mutation is a 1-bp deletion in exon 4. Contact MCW rat distribution at [email protected] 13793374 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2018-10-03) 13793374 RGD 2026-09-26 02:42:10 0
SS-Cgnl1em1Mcwi
 
Resource Report
Resource Website
RRID:RGD_13799346 Rattus norvegicus CRISPR/Cas9 system was used to introduce a 80-bp deletion on exon 2 of Cgnl1 gene in SS/JrHsdMcwi embryos Contact MCW rat distribution at [email protected] 13799346 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2018-10-10) 13799346 RGD 2026-09-26 02:42:10 0
SD-Cd55em6Mcwi
 
Resource Report
Resource Website
RRID:RGD_13207492 Rattus norvegicus CRISPR/Cas9 system was used to introduce a 4-bp deletion of exon 2 in the rat Cd55 gene of Crl:SD embryos. Contact MCW rat distribution at [email protected] 13207492 mutant Rat Genome Database (RGD) RGD Live Animals (as of 2017-08-02) 13207492 RGD 2026-09-26 02:42:09 0
F344-Il2rgem1Iexas
 
Resource Report
Resource Website
RRID:RGD_13464263 Rattus norvegicus This strain was established by CRISPR/Cas9 targeting rat Il2rg gene using electroporation. background strain: F344/Jcl. This strain shows severe combined immunodeficiency (SCID) caused by 5-bp deletion of Il2rg gene. This strain grows normally under SPF condition. National BioResource Project for the Rat in Japan 13464263 mutant Rat Genome Database (RGD) RGD Live Animals; Cryopreserved Sperm (as of 2018-01-02) 13464263 RGD 2026-09-26 02:42:09 0
SS-Kcnj13em1Mcwi
 
Resource Report
Resource Website
RRID:RGD_13207497 Rattus norvegicus CRISPR/Cas9 system was used to introduce a mutation in the Kcnj13 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 1-bp insertion of exon 2 in the Kcnj13 gene. Contact MCW rat distribution at [email protected] 13207497 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2021-11-03) 13207497 RGD 2026-09-26 02:42:10 0
SS-P2ry2em6Mcwi
 
Resource Report
Resource Website
RRID:RGD_13800869 Rattus norvegicus CRISPR/Cas9 system was used to introduce a mutation in the P2ry2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 132-bp deletion in exon 3 in the P2ry2 gene. Contact MCW rat distribution at [email protected] 13800869 mutant Rat Genome Database (RGD) RGD Unknown 13800869 RGD 2026-09-26 02:42:10 0
SD-Fhem1+/+
 
Resource Report
Resource Website
RRID:RGD_13792795 Rattus norvegicus A pair of TALENs targeting exon 1 of the Fh gene was injected into SD embryos to create Fh knock out mutants. The resulting mutation was an 11-bp deletion (acacctttggt) on exon 1 that caused premature stop of FH protein. Breeding of Fh +/- rats was done to generate wildtype (Fh+/+)and Fh (+/-). No homozygous mutant were observed. 13792795 mutant Rat Genome Database (RGD) RGD Unknown 13792795 RGD 2026-09-26 02:42:10 0
SS-Cgnl1em2Mcwi
 
Resource Report
Resource Website
RRID:RGD_13799348 Rattus norvegicus CRISPR/Cas9 system was used to introduce a 88-bp deletion on exon 2 of Cgnl1 gene in SS/JrHsdMcwi embryos Contact MCW rat distribution at [email protected] 13799348 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2018-10-10) 13799348 RGD 2026-09-26 02:42:10 0
SD-Fhem1+/-
 
Resource Report
Resource Website
RRID:RGD_13792794 Rattus norvegicus A pair of TALENs targeting exon 1 of the Fh gene was injected into SD embryos to create Fh knock out mutants. The resulting mutation was an 11-bp deletion (acacctttggt) on exon 1 that caused premature stop of FH protein. No homozygous -/- mutant was revealed in litters. 13792794 mutant Rat Genome Database (RGD) RGD Unknown 13792794 RGD 2026-09-26 02:42:10 0
WI-Slc6a4m1Hubr+/-
 
Resource Report
Resource Website
RRID:RGD_14390069 Rattus norvegicus The Slc6a4 knockout rat was generated by target-selected ENU-induced mutagenesis. An ENU-induced premature stop codon in exon 3 of the Slc6a4 gene in a female rat (Wistar from Crl) was identified.The heterozygoous mutant rats were used to generate homozygous Slc6a4 knock out rats. 14390069 mutant Rat Genome Database (RGD) RGD Unknown 14390069 RGD 2026-09-26 02:42:11 0
SD-Muc1em1Cgen
 
Resource Report
Resource Website
RRID:RGD_127345097 Rattus norvegicus The Muc1 knock out Sprague Dawley rats were produced by targeted gene mutation at rat Muc1 gene. The deletion was made by microinjection of TALENs and located in the exon 1 of rat Muc1 gene (Gen Bank: NM_012602.1). Genotyping was performed by PCR of tail DNA using primers specific for the rat MUC1 gene with forward primer 5′-CTAGCAAGCCTAAAAGGTGAGAGGT-3′ and reverse primer 5′-ACGAAGAGCATTTGCCTACTC-3′, followed by DNA sequencing analysis. Cyagen Biosciences Inc., Guangzhou, China 127345097 mutant Rat Genome Database (RGD) RGD Unknown 127345097 RGD 2026-09-26 02:42:10 0
F344-Prkar1bem2Tua
 
Resource Report
Resource Website
RRID:RGD_150519901 Rattus norvegicus CRISPR/Cas9 system containing guide RNAs targeting exon 2 and intron 2 were introduced into the F344/Stm embryos using a super electroporator NEPA 2. This mutant strain F344-Prkar1bem2Tua carried a 13-bp frameshift deletion in exon2 creating a premature stop codon in the Prkar1b transcripts. Expression levels of Prkar1b transcripts and protein are significantly decreased in the mutants. 150519901 mutant Rat Genome Database (RGD) RGD Unknown 150519901 RGD 2026-09-26 02:42:11 0
SD-Hamp em1Jfcol +/-
 
Resource Report
Resource Website
1+ mentions
RRID:RGD_36174030 Rattus norvegicus Hamp KO, Sprague-Dawley rats were generated by Transposagen Biopharmaceuticals (Lexington, KY). Four different genetically engineered rat lines, each with different sized Hamp deletions (with or without concurrent insertions), were created using TALEN technology. SD-Hamp em1Jfcol +/- (RGD: 36174030) is heterozygous carrying a 169-bp deletion between exons 2 & 3 of rat Hamp gene. Rat Resource & Research Center (RRRC) 36174030 mutant Rat Genome Database (RGD) RGD Cryopreserved Sperm (as of 2020-07-28) 36174030 RGD 2026-09-26 02:42:11 1
SD-Scn9a*tm1Amgn/Crl
 
Resource Report
Resource Website
1+ mentions
RRID:RGD_150429825 Rattus norvegicus Exon 25 of the rat Scn9a gene was replaced with the human SCN9A exon counterpart (exon 26) using ZFN technology. The mRNAs of the active ZFN pair targets middle region of the exon (CACCATCATGGTTCTTATAtgcctcAACATGGTAA CCATGATG, ZFN binding sites in uppercase). Charles River Laboratories 150429825 mutant Rat Genome Database (RGD) RGD Unknown 150429825 RGD 2026-09-26 02:42:10 1
WI-Oprl1m1Hubr+/-
 
Resource Report
Resource Website
RRID:RGD_13792570 Rattus norvegicus The original mutants were created by target-selected ENU-induced mutagenesis in a Brown Norway background. The animals were outcrossed for two generations on a Brown Norway background. they were subsequently backcrossed on a Wistar (Crl:WI) background for four generations. Backcrossings were performed to eliminate possible additional mutations induced by ENU-mutagenesis. Heterozygous oprl1+/- rats were crossed to generate the experimental animals. A C to G transversion at position 3657 in the oprl1 gene (ENSRNOG00000016768), resulting into a premature stop codon (TAC>TAG) in the third exon. 13792570 mutant Rat Genome Database (RGD) RGD Unknown 13792570 RGD 2026-09-26 02:42:10 0
SD-Bace1em1Sage-/-
 
Resource Report
Resource Website
RRID:RGD_13782146 Rattus norvegicus Bace1 (-/-) rats were generated by SAGE Labs using zinc-finger nuclease (ZFN) technology to create a 137-base pair deletion spanning the translation initiation start site in exon 1 of the rat Bace1 gene, corresponding to chr8:48,766,315-48,766,452 (RGSC 5.0/rn5 assembly) 13782146 mutant Rat Genome Database (RGD) RGD Unknown 13782146 RGD 2026-09-26 02:42:10 0
SD-Lepem1Sage+/+
 
Resource Report
Resource Website
RRID:RGD_13792575 Rattus norvegicus These wild type rats are littermates of homozygous knockout rats from heterozygote matings. The Lepr knockout model possesses a 151 bp deletion spanning the exon 1/intron 1 junction of the Leptin gene. Homozygous knockout rats display loss of Leptin protein via Western blot. Homozygous knockout rats demonstrate significant weight gain compared to wild type littermates. Homozygous knockout rats show significantly elevated serum cholesterol levels 13792575 mutant Rat Genome Database (RGD) RGD Unknown (as of 2018-09-13) 13792575 RGD 2026-09-26 02:42:10 0
SD-Lepem1Sage+/-
 
Resource Report
Resource Website
RRID:RGD_13792573 Rattus norvegicus This ZFN model possesses a 151 bp deletion spanning exon 1/intron 1 junction of Leptin gene. Homozygous knockout rats display loss of Leptin protein via Western blot. Homozygous knockout rats demonstrate significant weight gain compared to wild type littermates. Homozygous knockout rats show significantly elevated serum cholesterol levels Horizon Discovery 13792573 mutant Rat Genome Database (RGD) RGD Cryopreserved Embryo (as of 2018-09-13) 13792573 RGD 2026-09-26 02:42:10 0

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