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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
h∆∆HTA∆HTZ-F1B1 Resource Report Resource Website |
RRID:TSC_SD02633 | Tetrahymena thermophila | HTA/HTZ1 triple KO heterokaryons;From mating of h∆∆HTA-G6A and h∆HTZ1-G311A1; made with B*VII From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTA1 (TTHERM_00790790), HTA2 (TTHERM_00316500), HTA3 (TTHERM_00143660) | Micronucleus: Neo2 knockout of HTAX, HTA1, HTAZ | SD02633 | htax[∆::neo2]/htax[∆::neo2]; hta1[∆::neo2]/hta1[∆::neo2]; htaz[∆::neo2]/htaz[∆::neo2] (mp-r?, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:19822522 | 2025-04-20 03:37:35 | 0 | ||||
g:H3.2+GFP/H3.3-42-1-n* Resource Report Resource Website |
RRID:TSC_SD01946 | Tetrahymena thermophila | non-star side of H3.2+GFP germline replacement heterokaryon. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHT3 (TTHERM_00016170), HHT2 (TTHERM_00189180) | Micronucleus: GFP tagged HHT2 into HHT3 locus | SD01946 | hht3[5’neo2,∆,::(HHT2,GFPc)]/hht3[5’neo2,∆,(::HHT2,GFPc)] (?) | TSC, Tetrahymena Stock Center | TSC | PMID:16738316 | 2025-04-20 03:37:35 | 0 | ||||
HTB1-A2b Resource Report Resource Website 1+ mentions |
RRID:TSC_SD02088 | Tetrahymena thermophila | ∆∆HTB knockout heterokaryons rescued by HTB1. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTB1 (TTHERM_00633360), HTB2 (TTHERM_00283180) | Micronucleus: neo2 KO of HTB1 and HTB2 coding Macronucleus: HTB1 | SD02088 | htb1[∆::neo2]/htb1[∆::neo2]; htb2 [∆::neo2]/htb2 [∆::neo2] (htb1[∆::neo2]/HTB1 ; htb2 [∆::neo2]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:19822522 | 2025-04-20 03:37:35 | 1 | ||||
HTA1-G1 15B4 Resource Report Resource Website |
RRID:TSC_SD01395 | Tetrahymena thermophila | HTA1 Germline knockout heterokaryon. Transformed CU428 X B2086 with pQR10B (removes all coding, replaces with neo cassette). It can mate with HTA1 G1 14B, From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTA1 (TTHERM_00790790) | Micronucleus: Neo2 cassette knockout of HTAX coding region | SD01395 | hta1[∆::neo2]/hta1[∆::neo2; CHX1/CHX1; mpr1?/mpr1? (mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:11430834 PMID:12665578 |
2025-04-20 03:37:35 | 0 | ||||
BLTGLT1-3 Resource Report Resource Website |
RRID:TSC_SD02246 | Tetrahymena thermophila | BLT germline heterokaryon, homozyous KO in mic, pm sensitive (120 ug/ml) Cd induced Neo cassette (1.2 ug/ml)--MTT promoter, Neo coding, BTU2 terminator. Construct pBLTMKO, Mates with BLTGL5-1 and 5-2. From the Gorovsky lab, University of Rochester. | BLT1 (TTHERM_01104960) | Micronucleus: Neo3 replaces BLT coding | SD02246 | blt1-1[∆,neo3]/ blt1-1[∆,neo3]; MPR1-?/ MPR1-? (BLT1; mpr1-1; mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:36 | 0 | |||||
htb1-K4R-B2b Resource Report Resource Website |
RRID:TSC_SD02093 | Tetrahymena thermophila | ∆∆HTB knockout heterokaryons rescued by htb1-K4R. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTB1 (TTHERM_00633360), HTB2 (TTHERM_00283180) | Micronucleus: neo2 KO of HTB1 and HTB2 coding Macronucleus: Mutated HTB1 with K4R | SD02093 | htb1[∆::neo2]/htb1[∆::neo2]; htb2 [∆::neo2]/htb2 [∆::neo2] (htb1[∆::neo2]/htb1[K4R] ; htb2 [∆::neo2]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:19822522 | 2025-04-20 03:37:35 | 0 | ||||
IA481 Resource Report Resource Website |
RRID:TSC_SD01443 | Tetrahymena thermophila | A complex phenotype with contractile vacuole pores too close to the oral apparatus, and clockwise slippage of oral primordia. Similar to hpo1-1, though much less extensively studied. A sister clone to IA480. Submitted by Joseph Frankel, University of Iowa | HPO1 (hypoangular) | SD01443 | hpo1-4/hpo1-4 (hpo1-4, IV) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:36 | 0 | ||||||
HHT2S10AS28A-4 Resource Report Resource Website |
RRID:TSC_SD02376 | Tetrahymena thermophila | Mate Yifan Liu’s ∆H3 2-6 x ∆H3 10-6 homozygous heterokaryons (∆HHT1 with neo, and ∆HHT2/HHF2 with neo2 in mic) assorted to Paromomycin sensitive in mac. Shoot with pHHT2S10AS28A #6-later after seq.transformant found a wrong nucleotide~25 bases upsteam of ATG, transformant seems normal. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHT2 (TTHERM_00189180) | Micronucleus: Neo knockout of HHT1, HHT2, HHF1 Macronucleus: KO of HHT1, HHF1, and for HHT2 have mutations S10A and S28A | SD02376 | hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆,::neo2]/hhf2,hht2[∆,::neo2] (hht1[∆::neo2]; hhf2,hht2[∆,::neo2]/ hht2[S10A,S28A]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 PMID:10199406 |
2025-04-20 03:37:35 | 0 | ||||
HHT2S28A-C Resource Report Resource Website |
RRID:TSC_SD02379 | Tetrahymena thermophila | Mate Yifan Liu’s ∆H3 2-6 x ∆H3 10-6 homozygous heterokaryons (∆HHT1 with neo, and ∆HHT2/HHF2 with neo2 in mic) assorted to Paromomycin sensitive in mac. Shoot with pHHT2S28A#9. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHT2 (TTHERM_00189180) | Micronucleus: Neo knockout of HHT1, HHT2, HHF2 Macronucleus: KO of HHT1, HHF2, and for HHT2 have mutation S28A | SD02379 | hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆,::neo2]/hhf2,hht2[∆,::neo2] (hht1[∆::neo2]; hhf2,hht2[∆,::neo2]/ hht2[S28A]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 PMID:10199406 |
2025-04-20 03:37:35 | 0 | ||||
SB1813 Resource Report Resource Website |
RRID:TSC_SD01969 | Tetrahymena thermophila | Not useful for mapping loci on MIC chromosome 3R. One parent was missing this chromosome arm, so the progeny were not heterozygous. Submitted by Eduardo Orias, University of California, Santa Barbara | SD01969 | chx1-1/Chx1-1[C3]; MAT2/MAT3 (chx1-1; MAT3; cy-r, I) | TSC, Tetrahymena Stock Center | TSC | PMID:10880474 | 2025-04-20 03:37:36 | 0 | ||||||
MU137 Resource Report Resource Website |
RRID:TSC_SD03073 | Tetrahymena thermophila | Y607 is in a putative SH2 binding site. ASI2 is nonessential for vegetative growth. Matings between ASI2Y607F somatic replacement strains have reduced fertility and delayed endocycling during MAC development. For paromomycin resistance, add 0.5 ug/ul CdCl2 along with the parmomycin. | ASI2 (TTHERM_00191480) | Macronucleus: ASI2 replaced with ASI2Y607F | SD03073 | (pm-r, II) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:36 | 0 | |||||
CU724 Resource Report Resource Website 1+ mentions |
RRID:TSC_SD00480 | Tetrahymena thermophila | Micronucleus: btu1-1::btu1-1M350K/btu1-1::btu1-1M350K (homozygous) Macronucleus: btu1-1::btu1-1M350K HHF1::neo2 | SD00480 | chx1-1/chx1-1 (chx1-1; cy-r, mp-r, ory-r, pm-r, tax-r, ?) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:35 | 1 | |||||||
FLAG-HA-TWI1 (7)-9-2 Resource Report Resource Website |
RRID:TSC_SD02782 | Tetrahymena thermophila | All somatic TWI1 was replaced by FLAG-HA-TWI1 construct. CU427 background. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | TWI1 (TTHERM_01161040) | Macronucleus: FLAG-HA tagged TWI1 with neo3 replaced all TWI1 | SD02782 | chx1-1/chx1-1 (twi1[3’neo3, FLAG-HA]; pm-r, VI) | TSC, Tetrahymena Stock Center | TSC | PMID:12297043 | 2025-04-20 03:37:35 | 0 | ||||
IA379 Resource Report Resource Website 1+ mentions |
RRID:TSC_SD00642 | Tetrahymena thermophila | A mutation that brings about a broadening of oral and CVP domains. Allelic with bcd 1-1 (clones IA342 and IA344). Exhibits conjugal block, primarily due to failure of nuclear fusion. | BCD1 (broadened cortical domains) | SD00642 | bcd1-2/bcd1-2 (bcd1-2; bcd1, V) | TSC, Tetrahymena Stock Center | TSC | PMID:1818197 PMID:1743392 |
2025-04-20 03:37:35 | 1 | |||||
SB1822 Resource Report Resource Website |
RRID:TSC_SD01977 | Tetrahymena thermophila | Not useful for mapping loci on MIC chromosome 3R. One parent was missing this chromosome arm, so the progeny were not heterozygous. Submitted by Eduardo Orias, University of California, Santa Barbara | SD01977 | chx1-1/Chx1-1[C3]; MAT2/MAT3 (chx1-1; MAT2; cy-r, IV) | TSC, Tetrahymena Stock Center | TSC | PMID:10880474 | 2025-04-20 03:37:36 | 0 | ||||||
H3.4-Flag-4 Resource Report Resource Website |
RRID:TSC_SD01857 | Tetrahymena thermophila | Mac transformant. Somatic replace HHT4 gene with HHT3-Flag sequence. Neo2 in 5’ flanking of HHT3 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTT4 (TTHERM_00016200), HHT3 (TTHERM_00016170) | Macronucleus: N-terminalFlag tagged HHT3 put into HHT4 locus, not sure if complete replacement | SD01857 | mpr1-1/mpr1-1 (?HHT4/hht4[∆, HHT3, 5’neo2,FLAGc]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 PMID:9343391 |
2025-04-20 03:37:36 | 0 | ||||
∆PDD2-som-Bc1 Resource Report Resource Website |
RRID:TSC_SD02032 | Tetrahymena thermophila | Mates with CU427, CU428, ∆PDD2-som-BC4, BC-5. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | PDD2 (TTHERM_00283530) | Macronucleus: PDD2 with neo2 replacing the 5’ part of coding | SD02032 | (pdd2[∆?::neo2]; Progeny of B2086XCU428 transformation Somatic KO of PDD2 gene, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:10557212 PMID:10805754 |
2025-04-20 03:37:37 | 0 | ||||
HTA1-G1 14B11 Resource Report Resource Website |
RRID:TSC_SD02671 | Tetrahymena thermophila | HTA1 Germline knockout heterokaryon. Transformed CU428 X B2086 with pQR10B (removes all coding, replaces with neo cassette). It can mate with HTA1 G1 15B. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTA1 (TTHERM_00790790) | Micronucleus: Neo2 cassette knockout of HTAX coding region | SD02671 | hta1[∆::neo2]/hta1[∆::neo2; CHX!/CHX1; mpr1?/mpr1? (mp-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:12665578 PMID:11430834 |
2025-04-20 03:37:36 | 0 | ||||
IA333 Resource Report Resource Website |
RRID:TSC_SD01461 | Tetrahymena thermophila | janus phenotype: partially reversed oral apparatus on the dorsal surface; two contractile-vacuole pore sets. Also the only temperature-sensitive janus mutant. There is very little expression of the janus phenotype at 28° C, strong expression at 39°. Submitted by Joseph Frankel, University of Iowa | JANB (janus B) | SD01461 | janB-1/janB-1 (janB-1, III) | TSC, Tetrahymena Stock Center | TSC | PMID:28305473 | 2025-04-20 03:37:37 | 0 | |||||
∆H3 all, gl KO #37 Resource Report Resource Website |
RRID:TSC_SD01862 | Tetrahymena thermophila | homozygous, Neo cassette knockout before we knew there was HHT4 From the Gorovsky lab, University of Rochester. | HHT (TTHERM_00570560, TTHERM_00189180, TTHERM_00016170) | Micronucleus: Neo3 KO of major H3s and HHT3 | SD01862 | hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; hht3[∆::neo2]/hht3[∆::neo2] (mpr1-1; pm-s, mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:15701804 PMID:16908532 |
2025-04-20 03:37:37 | 0 |
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