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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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SD-Spon2em1Holi Resource Report Resource Website |
RRID:RGD_329333019 | Rattus norvegicus | This Spon2 knockout mutant was produced by injecting TALENs targeting exon 2 of rat Spon2 into Sprague Dawley embryos. Founder #4-1 (a1) carrying a 22-bp deletion was chosen to produce heterozygous and homozygous rats. | 329333019 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 329333019 | RGD | 2026-09-26 02:42:15 | 0 | |||||
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SD-Ddah1em1Ywxu Resource Report Resource Website |
RRID:RGD_151347605 | Rattus norvegicus | CRISPR-Cas9 technique was used to generate DDAH1-/- rats on Sprague-Dawley background. Genome deletion in exon 1 was confirmed by PCR analysis with the primers:DDAH1-F (5'-GCGCTGCTCTCGGGAAGA-3') and DDAH1-R (5'-GGGTGATGAGGGCGGTCT-3'). | 151347605 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 151347605 | RGD | 2026-09-26 02:42:14 | 0 | |||||
|
SS-Chr 3BN.Il2rgem1Mcwi/Mcwi Resource Report Resource Website |
RRID:RGD_155791425 | Rattus norvegicus | The IL2Rg gene was targeted in the SS/JrHsdMcwi rat by TALEN injection into single-cell rat embryos. Once established, a homozygous (RGD:12790632) female rat from the SSIL2Rg line was intercrossed with a homozygous SS.BN3 (RGD:1358154) male to yield heterozygous SS.BN3IL2Rg offspring (F1), followed by brother-sister mating to yield homozygous SS. BN3IL2Rg offspring by the F3 generation. This strain is Immunodeficient Ilrg (X-SCID) mutant consomic line. | 155791425 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 155791425 | RGD | 2026-09-26 02:42:14 | 0 | |||||
|
SD-Bmal1em1Mcwi Resource Report Resource Website |
RRID:RGD_155598601 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 58-base pair deletion in exon 6 in the rat Bmal1 gene of Crl:SD embryos. The deletion caused a premature stop codon in exon 6 resulting in a severe truncation of the Bmal1 protein. Contact MCW rat distribution at [email protected] | 155598601 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 155598601 | RGD | 2026-09-26 02:42:15 | 0 | |||||
|
SD-Pde6bem1Cgen Resource Report Resource Website |
RRID:RGD_155631289 | Rattus norvegicus | This mutant strain was generated by microinjecting CRISPRs/Cas9 system targeting rat Pde6b. Pde6b knock out rat was successfully created. Cyagen Biosciences Inc, Santa Clara, CA, USA | 155631289 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 155631289 | RGD | 2026-09-26 02:42:14 | 0 | |||||
|
CD-Ctnsem3Vjupk Resource Report Resource Website |
RRID:RGD_155630633 | Rattus norvegicus | The mutant rat was produced by injecting Crl:CD(SD) zygotes with gRNA +Cas9 ribonucleoprotein complex targeting exon 3 of rat Ctns. The founder of this strain possessed a 8-bp insertion which results in frameshift and pre-mature stop truncated protein. | 155630633 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 155630633 | RGD | 2026-09-26 02:42:14 | 0 | |||||
|
SD-Flnaem1Ang Resource Report Resource Website |
RRID:RGD_155631278 | Rattus norvegicus | This mutant strain was generated by electroporating rat zygotes with CRISPRs/Cas9 system targeting exon12 of rat Flna into Crl:SD embryo. This mutant strain carries P637Q knock in the gene. | 155631278 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 155631278 | RGD | 2026-09-26 02:42:15 | 0 | |||||
|
F344-Txn1m1Kyo Resource Report Resource Website |
RRID:RGD_288084580 | Rattus norvegicus | This mutation Phe54Leu is an autosomal dominant mutation that appeared in a stock of F344/NSlc rats that had been mutagenized with N-ethyl-N-nitrosourea (ENU). Rats heterozygous for Txn1 (Txn1 /+) exhibited running seizures only in its juvenile stage. The rat called Adem rat, exhibited age dependent mitochondrial cytopathy (Adem). The rats were backcrossed for more than ten generations on the F344/NSlc inbred background to ensure other mutations induced by ENU was reduced. The causative gene was identified as a missense substitution (c. 160 T > C, p. Phe54Leu) in exon 3 of Txn1. | 288084580 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 288084580 | RGD | 2026-09-26 02:42:15 | 0 | |||||
|
SD-Mecp2em1Sage/Hsd Resource Report Resource Website 1+ mentions |
RRID:RGD_156430169 | Rattus norvegicus | The MeCP2 KO rat model was originally created at SAGE Labs, Inc. in St. Louis, MO and distributed out of the Boyertown, PA facility. The line continues to be maintained through the original SAGE Labs animal inventory acquired by Envigo. The ZFN mutant rat strain was produced by injecting zinc finger nuclease targeting rat Mecp2 into Sprague Dawley embryos. This mutant rat has a knockout of the methyl CpG binding protein 2 (Mecp2). ENVIGO | 156430169 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2023-02-22) | 156430169 | RGD | 2026-09-26 02:42:14 | 2 | |||||
|
W-Plp1md/Nya Resource Report Resource Website 1+ mentions |
RRID:RGD_1358918 | Rattus norvegicus | Wistar rats were received in 1957 from Walter Reed Army Medical Center. In 1977, three ofsprings exhibited body tremor. Two of these had hydrocephalus and the brain of the third was normal. The mother rat and four of its clinically mormal youngs along with three adult males were breed as nuclear breeders. | 1358918 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 1358918 | RGD | 2026-09-26 02:41:46 | 1 | |||||
|
Gunn-Ugt1a1j/BluHsd Resource Report Resource Website |
RRID:RGD_1357186 | Rattus norvegicus | This mutation was first observed in normal Wistar albino rats in a breeding colony at Cannaught Laboratories in 1934. Jaundice was evident at birth or shortly after and was persistant throughout life. Harlan | 1357186 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 1357186 | RGD | 2026-09-26 02:41:46 | 0 | |||||
|
BN-Adora2am2Mcwi Resource Report Resource Website |
RRID:RGD_1599757 | Rattus norvegicus | Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. Q310L mutation is generated from the codon change CAG/CTG of rat Adora2a. | 1599757 | mutant | Rat Genome Database (RGD) | RGD | Extinct (as of 2016-10-24) | 1599757 | RGD | 2026-09-26 02:41:48 | 0 | |||||
|
BN-Has2m1Mcwi Resource Report Resource Website |
RRID:RGD_1599756 | Rattus norvegicus | Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. Y344Stop mutation is generated from the codon change TAT/TAA. | 1599756 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 1599756 | RGD | 2026-09-26 02:41:48 | 0 | |||||
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BN-Tgfbr2m1Mcwi Resource Report Resource Website |
RRID:RGD_1579688 | Rattus norvegicus | Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. T289M mutation is generated from the codon change ACG/ATG. | 1579688 | mutant | Rat Genome Database (RGD) | RGD | Extinct (as of 2017-01-26) | 1579688 | RGD | 2026-09-26 02:41:49 | 0 | |||||
|
HOB-Unc5chob/Snk Resource Report Resource Website |
RRID:RGD_1554302 | Rattus norvegicus | Homozygous hobble rats that were taken from the inbred hobble rat colony. National BioResource Project for the Rat in Japan | 1554302 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 1554302 | RGD | 2026-09-26 02:41:48 | 0 | |||||
|
FHH-Klf6m1Mcwi Resource Report Resource Website |
RRID:RGD_1579712 | Rattus norvegicus | Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. V135G mutation is generated. | 1579712 | mutant | Rat Genome Database (RGD) | RGD | Extinct (as of 2017-01-26) | 1579712 | RGD | 2026-09-26 02:41:49 | 0 | |||||
|
BN-Birc3m1Mcwi Resource Report Resource Website |
RRID:RGD_1579681 | Rattus norvegicus | Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations.W76G mutation is generated. | 1579681 | mutant | Rat Genome Database (RGD) | RGD | Extinct (as of 2016-10-24) | 1579681 | RGD | 2026-09-26 02:41:49 | 0 | |||||
|
SS-Htr1am2Mcwi Resource Report Resource Website |
RRID:RGD_1599767 | Rattus norvegicus | Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. G76R mutation is generated from the codon change GGC/CGC. | 1599767 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 1599767 | RGD | 2026-09-26 02:41:49 | 0 | |||||
|
FHH-Bdkrb2m1Mcwi Resource Report Resource Website |
RRID:RGD_1579895 | Rattus norvegicus | Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. I214T mutation is generated. | 1579895 | mutant | Rat Genome Database (RGD) | RGD | Extinct (as of 2016-10-24) | 1579895 | RGD | 2026-09-26 02:41:49 | 0 | |||||
|
SS-Bdkrb2m2Mcwi Resource Report Resource Website |
RRID:RGD_1599762 | Rattus norvegicus | Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. E178V mutation is generated from the codon change GAA/GTA. | 1599762 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 1599762 | RGD | 2026-09-26 02:41:50 | 0 |
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