Searching the RRID Resource Information Network
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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10010
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10010
Proper citation: RRID:RGD_10010 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10015
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10015
Notes: An outbred stock of fawn hooded rats introduced into Europe by Tschopp in the early 1970s. Maintained as an outbred stock until the mid-1980s, then brother x sister mating initiated by A.P. Provoost to produce two strains designated FHH (also known as FHR) and FHL, which differ in hypertension and proteinuria. The colony was transferred to Erasmus University.
Proper citation: RRID:RGD_10015 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10014
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10014
Proper citation: RRID:RGD_10014 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=61000
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 61000
Notes: Okamoto 1963 from outbred Wistar Kyoto rats. Bred from a male with mild hypertension, mated with a female with high blood pressure. Brother x sister mating with continued selection for high blood pressure (Okamoto 1969, Okamoto et al 1972). A number of sublines have been developed with a tendency to develop cardiovascular lesions and stroke (see particularly SHRSP) (Nagaoka et al 1976), and hypercholesterolemia (Yamori 1984). For a recent review see Yamori, (1994). However, there is no evidence for substrain differentiation among SHR stocks from the major commercial suppliers in the USA both respect to phenotype and DNA fingerprints (Blizard et al, 1991). Strain WKY, developed from the same base populations is sometimes used as a normotensive control, though its use as such must be questioned as it differs at many genetic marker loci (Festing and Bender 1984, and see also strain WKY). Stelzin et al (1992) found that SHR and WKY shared only 50% of their DNA fingerprint bands, whereas SS and SR shared about 80% of bands. Most authorities suggest that WKY alone is not a good control strain, and that for most comparative studies several normotensive strains should be used. There is an extensive literature on the characteristics of SHR. DeJong (1984) provides a useful comparative review of this and other hypertensive strains, and there are regular symposia on hypertensive rat strains (see J. Hypertension 4(suppl):S1-S541, 1986, and Jpn. Heart J. 28:567-648).
Proper citation: RRID:RGD_61000 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10029
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10029
Notes: As for MNR except selection was for high defecation response in the open field. To Harrington in 1965 at F25 and to NIH in 1964 at F18+ (Hansen et al 1982).
Proper citation: RRID:RGD_10029 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10021
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10021
Notes: In 1969 outbred Sprague-Dawley rats were selected for high systolic blood pressure using an indirect plethysmographic technique in pre-warmed unrestrained conscious rats. Three pairs were originally selected, and selection was continued with brother x sister mating. Strain LN was maintained as a normotensive control, and LL as a hypotensive strain. (see Vincent et al 1984, and Vincent and Sassard, 1994 for reviews).
Proper citation: RRID:RGD_10021 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10026
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Extinct
Alternate IDs: 10026
Notes: To N 1964 at F18+? from Maas. Developed by Broadhurst, 1954, from a commercial stock, with selection for low defecation response in an open field. A number of parallel sublines are in existence; these differ at least at the agouti and the major histocompatibility loci.
Proper citation: RRID:RGD_10026 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=10027
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 10027
Notes: To Harrington in 1965 at F25 (Harrington 1981).
Proper citation: RRID:RGD_10027 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14695055
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: RGD_14695055, 14695055, RRRC_794, RRRC_0794, RRRC_00794
Notes: Inbred hypertension model linked to a mutation in Add1 gene that has been validated as one of the genes linked to hypertension in numerous human genetic studies. Inbred strain originally developed by Dr. Bianchi in Milan in 1979. Rat Resource and Research Center
Proper citation: RRID:RRRC_00794 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11667072
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_11667072, 11667072, RRRC_538, RRRC_0538, RRRC_00538
Notes: This phenotype arose spontaneously during the third generation of selective breeding for decreased intravenous drug self-administration in Wistar rats (see RGD:6482259). After 10 weeks of age no drug administration is needed to see phenotype in which animals exhibits motor abnormalities with degenerative changes in cerebellar Purkinje cells. It appears to be transmitted in an autosomal recessive pattern. Animals have an abnormal swaying gait, which is readily identified as a slow (2 to 3 cycles per second) tremor. Rat Resource and Research Center
Proper citation: RRID:RRRC_00538 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150429818
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery (as of 2021-09-30)
Alternate IDs: RGD_150429818, 150429818, RRRC_562, RRRC_0562, RRRC_00562
Notes: Inbred from a single pair of SsN line rats obtained from Harlan Sprague Dawley (Alabama colony). Maintained at the Medical College of Wisconsin since 1995. To confirm homozygosity, the strain was tested with 200 microsatellite markers (genome-wide scan at 20cM) all of which were homozygous for all regions tested (Cowley et al. 2000, Physiol. Genomics. 2:107-115). This strain was maintained at RRRC. Rat Resource & Research Center
Proper citation: RRID:RRRC_00562 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11667081
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Sperm (as of 2017-01-26)
Alternate IDs: RGD_11667081, 11667081, RRRC_784, RRRC_0784, RRRC_00784
Notes: Point mutation in Myo5a (Chromosome 8, end of exon 4)identified in In Berlin-Druckrey (BDIV) shaker rats Rat Resource and Research Center
Proper citation: RRID:RRRC_00784 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9999145
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: RGD_9999145, 9999145, RRRC_734, RRRC_0734, RRRC_00734
Notes: The F344/NCr rat strain was received into the NIH Genetic Resources program in 1987, now maintained at NCI Animal production program Rat Resource and Research Center
Proper citation: RRID:RRRC_00734 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245556
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: RGD_7245556, 7245556, RRRC_664, RRRC_0664, RRRC_00664
Notes: WKHT rats are derived from a cross between SHR and WKY. Brother/sister inbreeding of the hybrids and successive generations was performed, selecting for the hypertension, but not the behavioral hyperactivity, of the SHR. Rat Resource and Research Center
Proper citation: RRID:RRRC_00664 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=10000
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm; Cryorecovery
Alternate IDs: RGD_10000, 10000, RRRC_142, RRRC_0142, RRRC_00142
Notes: Curtiss and Dunning 1926 at the Columbia University Institute for Cancer Research. To Heston 1945 at F30, to National Institutes of Health 1950 at F41. Subsequent sublines from Dunning or NIH. Donated to RRRC from NIH Animal Genetic Resource Bank (NIHAGR) Rat Resource and Research Center
Proper citation: RRID:RRRC_00142 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=153323320
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Live Animals; Cryopreserved Embryo; Cryorecovery (as of 2023-10-25)
Alternate IDs: RGD_153323320, 153323320, RRRC_00173
Notes: Origin: as for MNR except selection was for high defecation response in the open field. To Harrington in 1965 at F25 and to NIH in 1964 at F18+ (Hansen et al 1982). Now is available at Rat Resource & Research Center Rat Resource and Research Center, RGD HRDP, contact HRDP
Proper citation: RRID:RRRC_00173 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=629509
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Live Animals; Cryorecovery
Alternate IDs: RGD_629509, 629509, RRRC_293, RRRC_0293, RRRC_00293
Notes: An outbred stock of fawn hooded rats introduced into Europe by Tschopp in the early 1970s. Maintained as an outbred stock until the mid-1980s, then brother x sister mating initiated by A.P. Provoost to produce two strains designated FHH (also known as FHR) and FHL, which differ in hypertension and proteinuria. The colony was transferred to Erasmus University. Rat Resource and Research Center, RGD HRDP, contact HRDP
Proper citation: RRID:RRRC_00293 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=2307319
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo
Alternate IDs: RGD_2307319, 2307319, RRRC_171, RRRC_0171, RRRC_00171
Notes: Wistar rats with brother x sister mating and selection for low systolic blood pressure as a normotensive control for MHS. Rat Resource and Research Center
Proper citation: RRID:RRRC_00171 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=6482676
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_6482676, 6482676, RRRC_440, RRRC_0440, RRRC_00440
Notes: The Occidental LoS (low-saccharin-consuming) rat strain was developed from a male Holtzman Sprague-Dawley rat that did not voluntarily consume saccharin. This male was mated to several Holtzman Sprague-Dawley females and offspring displaying low saccharin consumption were selected. Selective breeding was continued in which offspring with low saccharin consumption (see phenotyping protocol) were bred. To maintain the outbred status of this colony the donor backcrosses to Hsd:SD every 4-6 generations. Rat Resource and Research Center
Proper citation: RRID:RRRC_00440 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1578695
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: RGD_1578695, 1578695, RRRC_68, RRRC_068, RRRC_0068, RRRC_00068
Notes: Selective breeding of Long-Evans in active two-way shuttle box for high avoidance resulted in these SHA rats. Rat Resource and Research Center
Proper citation: RRID:RRRC_00068 Copy
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