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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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HTA3-T84G Resource Report Resource Website |
RRID:TSC_SD02463 | Tetrahymena thermophila | Cell has wt H2A.Z in its locus, and a mutated H2A.Z RRRRRR copy in MTT1 locus, neo2 cassette is inserted at 5’ of MTT, complete replacement ?. Somatic transformation. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTA3 (TTHERM_00143660) | Macronucleus: inserted HTAZ with K4R, K7R, K10R, K13R K16R, , K21R Into MTT1 locus and neo2 in 5’flanking of MTT1 | SD02463 | mpr1-1/mpr1-1 (HTAZ ; MTT1/mtt1[5’neo2,∆::HTAZ(K4R,K7R,K10R,K13R K16R,,K21R)]; pm-r, H2A.Z RRRRRRneo regulated by MTT1 promoter, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:12665578 PMID:11430834 |
2025-04-20 03:37:15 | 0 | ||||
|
R-Tcd2-B2086 Resource Report Resource Website |
RRID:TSC_SD02506 | Tetrahymena thermophila | Using Complete somatic Neo4 knockout Tcd2 strains. Tcd2 gene was reintroduced with blasticidin cassette (H4-BSR-B) upstream. H3K27 methylation was recovered. Bsr/Bsr, Tcd2/Tcd2, Neo4/Neo4 This is what Wei wrote, not sure if the replacement was complete or if both resistance are still present. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HPL7 (TTHERM_00551070) | Macronucleus: TCD2 was knocked out with neo4, then the wt TCD2 gene with a bsr1cassette upstream was somatically reintroduced into the cell | SD02506 | (tcd2[∆?::neo4]/TCD2[5’bsr1]; Mix of pm-r and bs-r, II) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:15 | 0 | |||||
|
ATU5D-2 Resource Report Resource Website |
RRID:TSC_SD02229 | Tetrahymena thermophila | It is a progeny of conjugants of AAK02.7XAAKO5.5 transformed with pATU5D derived from pTUB100E3-PvuII (linearized)where the ATU1 gene is marked with Hae III and Pvu II sites and E441D, E443D, E445D,E446D,E447D. Slow growth. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | ATU1 (TTHERM_00558620) | Micronucleus: neo replaces ATU1 coding Macronucleus: ATU1 with E441D, E443D, E445D, E446D, E447D or neo replacing coding of some ATU1 genes | SD02229 | atu1-1[Δ::neo1]/atu1-1[Δ::neo1]; mpr1-1/mpr1-1 or MPR1/MPR1 (atu1-1[Δ::neo1]/atu1[E441D, E443D, E445D,E446D,E447D ]; pm-r, mp-?, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:9037049 PMID:10831613 |
2025-04-20 03:37:15 | 0 | ||||
|
UCB1353 Resource Report Resource Website |
RRID:TSC_SD03323 | Tetrahymena thermophila | From the Winey Lab at the University of Colorado Boulder. | Sas6b | Micronucleus: TTHERM_00118700[∆::NEO2] | SD03323 | TTHERM_00137600[∆::NEO2] (TTHERM_00137600[∆::NEO2]; timing and location of basal body assembly, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:19158390 | 2025-04-20 03:37:16 | 0 | ||||
|
TWI7 KO 3-1 Resource Report Resource Website |
RRID:TSC_SD02870 | Tetrahymena thermophila | heterozygote TWI7 KO heterokaryon Partial TWI7 coding sequences were replaced by Neo3. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | TWI7 (TTHERM_00600450) | Micronucleus: Partial coding of TWI7 replaced by neo3 | SD02870 | MPR1-1/mpr1-1; TWI7/twi7[∆?::neo3] (mpr1-1; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:15 | 0 | |||||
|
OAD1 C11 Resource Report Resource Website |
RRID:TSC_SD01784 | Tetrahymena thermophila | Submitted by Jacek Gaertig. Originally created by D. Pennock. | SD01784 | oad1/oad1; chx1-1/chx1-1? (oad1; cy-s) | TSC, Tetrahymena Stock Center | TSC | PMID:20189389 PMID:8401477 |
2025-04-20 03:37:15 | 0 | ||||||
|
HMG C gl KO-H7 Resource Report Resource Website |
RRID:TSC_SD01388 | Tetrahymena thermophila | Obtained thru 1st round exclusion of ∆B∆C gl KO. Genotype confirmed by cross with 427 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HMGB (TTHERM_00660180) | SD01388 | homozygous HMG C KO with BSR (mp-r) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:15 | 0 | ||||||
|
XS 48 (4) [(HTA1 S1P+5R+4A+3R) 4] Resource Report Resource Website |
RRID:TSC_SD02199 | Tetrahymena thermophila | HTAX S1P+5R+4A+3R mutation somatic rescue strain of HTA1, HTA2 double knockout From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTA1 (TTHERM_00790790), HTA2 (TTHERM_00316500) | Micronucleus: HTAX and HTA1 KO with neo Macronucleus: Rescue with mutated HTAX with S1P, , K5R, K8R, K10R, K12R, K17R, S122A, k123R, S124A, K125R, K126R, T127A, S129A | SD02199 | htax[∆::neo2]/htax[∆::neo2]; hta1[∆::neo2]/hta1[∆::neo2] (hta1[∆::neo2], htax[∆::neo2]/htax [S1P,,K5R,K8R,K10R, K12R,K17R, S122A, k123R, S124A, K125R, K126R, T127A, S129A]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:17242195 | 2025-04-20 03:37:16 | 0 | ||||
|
UCB117 Resource Report Resource Website |
RRID:TSC_SD03288 | Tetrahymena thermophila | EF-hand mutant allele rescue of cen1∆ - D145A. From the Winey Lab at the University of Colorado Boulder. | CEN1 (TTHERM_00384910) | Micronucleus: cen1-1[∆::NEO2] Macronucleus: cen1-1[∆::NEO2]::cen1-EF3 | SD03288 | cen1-1[∆::NEO2] (cen1-1[∆::NEO2]::cen1-EF4; Basal body disorganization and stability defects (TS)., ?) | TSC, Tetrahymena Stock Center | TSC | PMID:21562224 | 2025-04-20 03:37:16 | 0 | ||||
|
RDP1-T2 Resource Report Resource Website |
RRID:TSC_SD02513 | Tetrahymena thermophila | Shot plasmid pRDP1::TAG-neo3 #110 into conjugating CU428 X B2086 but only got somatic strains, slow growth No other information, don’t know if complete replacement From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | RDR1 (TTHERM_00853150) | Macronucleus: HA-FLAG tagged RDR1 with neo3 in flank | SD02513 | (RDR1?/rdr1[neo3;HA,FLAG]; pm-r , ?) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:15 | 0 | |||||
|
DRH1g∆∆ D3-11F Resource Report Resource Website |
RRID:TSC_SD02599 | Tetrahymena thermophila | Homozygous homokaryon KO of DRH1 with neo4 cassette. Mates with DRH1g∆∆ C10-11F Gene is Dicer Related Helicase, sequence is fromTGD 69.m00174. Mating cells stop at mic selection after MeiosisII Gene is expressed at low level in starve and log, peak expression at 4 hr of conjugation. Somatic KO is complete, when mated they arrest after Meiosis II. Homozygous homokaryon KOs do not grow well. Needs Cd for pm resistance. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | DRH1 (TTHERM_00190830) | Micronucleus: neo4 at 5’end of coding, some coding remains Macronucleus: neo4 at 5’ end of coding, some coding remains | SD02599 | drh1[∆?::neo4]/drh1[∆?::neo4] (drh1[∆?::neo4]/drh1[∆?::neo4]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:15 | 0 | |||||
|
∆H1∆HHP1 #4 Resource Report Resource Website |
RRID:TSC_SD02637 | Tetrahymena thermophila | Complete somatic knockout of H1 andHHP1. See Hui Huang thesis for details. Max paromomycin 100 mg/ml. Retransform ∆HHP1 cells with ∆H1 construct. From the Gorovsky lab, University of Rochester. | HHO1 (TTHERM_00823720) + HHP1 (TTHERM_00705240) | SD02637 | (pm-r) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:16 | 0 | ||||||
|
hta1-K123R+htz1 K130R-G2b Resource Report Resource Website |
RRID:TSC_SD02403 | Tetrahymena thermophila | HTAX/HTAZ double mutant rescue; Rescue of h∆∆HTA∆HTZ1-F1B1 and B1C5 with Dryl's. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTA1 (TTHERM_00790790), HTA2 (TTHERM_00316500), HTA3 (TTHERM_00143660) | Micronucleus: Neo2 knockout of HTAX, HTA1, HTAZ Macronucleus: mutant HTAX and HTAZ rescue of mac KO | SD02403 | htax[∆::neo2]/htax[∆::neo2]; hta1[∆::neo2]/hta1[∆::neo2]; htaz[∆::neo2]/htaz[∆::neo2] (htax[K123R]/htax[∆::neo2]; hta1[∆::neo2]/hta1[∆::neo2]; htaz[K130R]/htaz[∆;;neo2]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:19822522 | 2025-04-20 03:37:15 | 0 | ||||
|
19877-1 Resource Report Resource Website |
RRID:TSC_SD01555 | Tetrahymena thermophila | Collected by Paul Doerder on 8/26/2008 from the pond designated SG69-4 in Guys Mills, PA (lat. 41 38.023, long. -79 53.514, elevation 1660 ft). Old pond sign says pond #19. Geographical area: Western Pennsylvania Collection number: 892 Has a micronucleus. Cech's self-splicing intron is present. Cytochrome oxidase I haplotype = WPA1 | SD01555 | (V) | TSC, Tetrahymena Stock Center | TSC | PMID:25973525 | 2025-04-20 03:37:15 | 0 | ||||||
|
g:H3.3+GFP-59-6* Resource Report Resource Website |
RRID:TSC_SD01952 | Tetrahymena thermophila | star side of H3.3+GFP germline replacement heterokaryon. From the Gorovsky lab, University of Rochester. | HHT3 (TTHERM_00016170) | Micronucleus: GFP tagged HHT3 | SD01952 | hht3[5’neo2,GFPc]/hht3[5’neo2,GFPc] (?) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 | 2025-04-20 03:37:15 | 0 | ||||
|
A1∆F11.1ns Resource Report Resource Website |
RRID:TSC_SD01798 | Tetrahymena thermophila | ACT1∆ KO homozygous in mic, heterokaryon From the Gorovsky lab, University of Rochester. | ACT1 (TTHERM_00190950) | Micronucleus: ACT1 with neo3 inserted at Sfu1 site | SD01798 | act1[208::neo3]/act1[208::neo3] (pm-s , mp-?, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:16524910 | 2025-04-20 03:37:16 | 0 | ||||
|
A447-1 Resource Report Resource Website |
RRID:TSC_SD01831 | Tetrahymena thermophila | It is a progeny of conjugants of AAK02.7 X AAKO5.5 transformed with pA447 derived from pTUB100E3-PvuII (linearized) where the ATU1 gene is marked with Hae III and Pvu II sites and E447A. From the Gorovsky lab, University of Rochester. | ATU1 (TTHERM_00558620) | Micronucleus: neo replaces ATU1 coding Macronucleus: ATU1 with E447A or neo replacing coding of some ATU1 genes | SD01831 | atu1-1[Δ::neo1]/atu1-1[Δ::neo1]; mpr1-1/mpr1-1 or MPR1/MPR1 (atu1-1[Δ::neo1]/atu1[E447A]; pm-r, mp-?) | TSC, Tetrahymena Stock Center | TSC | PMID:10831613 PMID:9037049 |
2025-04-20 03:37:16 | 0 | ||||
|
HA-TWI11 F2-5 Resource Report Resource Website |
RRID:TSC_SD02804 | Tetrahymena thermophila | Homozygous HA-tagged TWI 11 homokaryon.HA coding sequence was inserted just after the start codon of TWI11. neo3 cassette was inserted upstream of TWI11 coding. mates with HA-TWI11 F2-1, F2-8. From the Gorovsky lab, University of Rochester. | TWI11 (TTHERM_00144830) | Micronucleus: TWI11-HA with neo3 in 5’ region Macronucleus: TWI11-HA with neo3 in 5’ region | SD02804 | twi11[5’neo3,HAn]/twi11[5’neo3,HAn] (twi11[5’neo3,HAn]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:15 | 0 | |||||
|
BLTGLT1-2 Resource Report Resource Website |
RRID:TSC_SD02253 | Tetrahymena thermophila | BLT germline heterokaryon, heterozygous KO in mic, pm sensitive (120 ug/ml). Cd induced Neo cassette (1.2 ug/ml)--MTT promoter, Neo coding, BTU2 terminator. Construct pBLTMKO, From the Gorovsky lab, University of Rochester. | BLT1 (TTHERM_01104960) | Micronucleus: Neo3 replaces BLT coding | SD02253 | BLT1/ blt1-1[∆,neo3]; MPR1-?/ MPR1-? (BLT1; mpr1-1; mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:15 | 0 | |||||
|
he∆ccg+ - 1-1 Resource Report Resource Website |
RRID:TSC_SD02653 | Tetrahymena thermophila | Homozygous heterokaryon of ∆RPB3 (=cnjc). B2086 X Cu428 background, can mate with he∆ccg+-4-1. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | RPB3 (TTHERM_00193849) | Micronucleus: GFP replaces RPB3 coding, neo3 in 3’ flanking region. homozygous | SD02653 | rbp3[3’neo3,∆::GFP]/rbp3[3’neo3,∆::GFP];mpr1-1/mpr1-1; chx1-1/chx1-1 (mp-?, cy-?, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:15470252 | 2025-04-20 03:37:15 | 0 |
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