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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430328
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 156430328
Notes: Flinders Resistant Line Rat (FRL) was selectively bred from outbred Sprague Dawley for less response to an anticholinesterase agent than FSL. FRL is not more resistant to the anticholinesterase agent compared to other outbred rats. The FSL rat
partially resembles depressed individuals with phenotypes of reduced appetite and psychomotor function but exhibits normal hedonic
responses and cognitive function.
Proper citation: RRID:RGD_156430328 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=156430327
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 156430327
Notes: Flinders Sensitive Line Rat (FSL) was selectively bred from outbred Sprague Dawley for increased response an anticholinesterase agent. The FSL rat
partially resembles depressed individuals with phenotypes of reduced appetite and psychomotor function but exhibits normal hedonic
responses and cognitive function.
Proper citation: RRID:RGD_156430327 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=401901199
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 401901199
Notes: The lean SHHFcp/+ is heterozygous for the corpulent allele and is the control model for the obese SHHFcp/cp. The Breeding stock for this colony was transferred to Dr. Sylvia McCune at the University of Chicago Medical School in 1983 from the laboratory of J.E. Miller at G.D. Searle and Company. The animals were developed by backcrossing the SHROB rat to the SHR/N rat. Dr. McCune obtained the colony after the seventh backcross and continued to inbreed past 20 generations to fix the congestive heart failure trait. To Genetic Models, Inc. in 1994. To Charles River in 2001. Charles River Laboratories
Proper citation: RRID:RGD_401901199 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=401901198
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 401901198
Notes: The obese SHHFcp/cp are homozygous for the corpulent allele. The Breeding stock for this colony was transferred to Dr. Sylvia McCune at the University of Chicago Medical School in 1983 from the laboratory of J.E. Miller at G.D. Searle and Company. The animals were developed by backcrossing the SHROB rat to the SHR/N rat. Dr. McCune obtained the colony after the seventh backcross and continued to inbreed past 20 generations to fix the congestive heart failure trait. To Genetic Models, Inc. in 1994. To Charles River in 2001. Charles River Laboratories
Proper citation: RRID:RGD_401901198 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405878049
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 405878049
Notes: This the hypotensive strain established from the selective breeding In 1969. Outbred Sprague-Dawley rats were selected for systolic blood pressure trait using an indirect plethysmographic technique in pre-warmed unrestrained conscious rats. Three pairs were originally selected, and selection was continued with brother x sister mating. Strain LN was maintained as a normotensive control, and LH as a hypertensive strain. (see Vincent et al 1984, and Vincent and Sassard, 1994 for reviews). This LL is the parent to LL substrains maintained in other institutions.
Proper citation: RRID:RGD_405878049 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405878048
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 405878048
Notes: In 1969 outbred Sprague-Dawley rats were selected for high systolic blood pressure using an indirect plethysmographic technique in pre-warmed unrestrained conscious rats. Three pairs were originally selected, and selection was continued with brother x sister mating. Strain LN was maintained as a normotensive control, and LL as a hypotensive strain. (see Vincent et al 1984, and Vincent and Sassard, 1994 for reviews). This LH is the parent to LH substrains maintained in other institutions.
Proper citation: RRID:RGD_405878048 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405878050
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 405878050
Notes: This is the normotensive control strain established from the selective breeding In 1969. Outbred Sprague-Dawley rats were selected for systolic blood pressure trait using an indirect plethysmographic technique in pre-warmed unrestrained conscious rats. Three pairs were originally selected, and selection was continued with brother x sister mating. Strain LH was maintained as a hypertensive strain, and LL as a hypotensive strain. (see Vincent et al 1984, and Vincent and Sassard, 1994 for reviews). This LN is the parent to LN substrains maintained in other institutions.
Proper citation: RRID:RGD_405878050 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405878052
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 405878052
Notes: Originally developed before 1965 by Sidman from stock obtained from Sorsby of the Royal College of Surgeons, This RCS is the parent to RCS substrains maintained in other institutions.The RCS/LavRrrc substrain is available from Rat Resource & Research Center.
Proper citation: RRID:RGD_405878052 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405878051
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown (as of 2024-07-09)
Alternate IDs: 405878051
Notes: This strain has been selected for high open-field defecation (a test of emotional reactivity). The underlying genetic basis for this phenotype is not known. Originally selected by Broadhurst in 1954 for high open-field defacation (OFD) response in an open field. This MR is the parent to MR substrains maintained in other institutions.
Proper citation: RRID:RGD_405878051 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=407450403
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 407450403
Notes: Substrain of BN maintained at Shanghai laboratory animal center of the Chinese Academy of Sciences, Shanghai, China Shanghai laboratory animal center of the Chinese Academy of Sciences, Shanghai, China
Proper citation: RRID:RGD_407450403 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2325146
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 2325146
Notes: These were originally obtained from Veterinary Resource Branch, National Institutes of Health (Bethesda, MD) and maintained at University of Toledo, College of Medicine (Medical College of Ohio), Toledo, Ohio.
Proper citation: RRID:RGD_2325146 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=6218997
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 6218997
Notes: These were originally from Harvard University, Boston MA, then at UNESP, Botucatu, SP, Brazil, now maintained at Behavior Genetics Laboratory, SC, Brazil
Proper citation: RRID:RGD_6218997 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2303759
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2024-09-24)
Alternate IDs: 2303759
Notes: In 2001, abnormal incisors that had deteriorated and had a whitish chalk-like appearance were unexpectedly discovered in one male rat among Sprague-Dawley [Crj:CD(SD)IGS] rats (Masuyama, 2005). After that, this mutant phenotype was maintained by sib-mating. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2303759 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=6903881
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 6903881
Notes: 1962: Dr. L. K. Dahl found the mutant rat from SD at NIH; 1989: Moved to Eisai (Eisai Co., Ltd.); 1991: Moved to BMR Institute for breeding; 1994: Started selling by SLC, Shizuoka, Japan
Proper citation: RRID:RGD_6903881 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8662449
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 8662449
Notes: LOU/M strain maintained at Max-Delbruck-Center for Molecular Medicine, Berlin, Germany
Proper citation: RRID:RGD_8662449 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8553005
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 8553005
Notes: To Animal Resources Centre, Australia from Harlan. Animal Resources Centre, Australia
Proper citation: RRID:RGD_8553005 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8142383
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 8142383
Notes: Animals transferred from Harvard University/Brigham (Dr Klaus Lindpaintner) originating from SHRSP colony at University of Heidelberg
Proper citation: RRID:RGD_8142383 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=9831158
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Live Animals (as of 2020-10-05)
Alternate IDs: 9831158
Notes: Strain developed by Prof. Borislav Nakic, Prof. Silobrcic and Prof. Andrija Kastelan from outbred Wistar rats during 1960s, maintained at Department of Animal Physiology,Faculty of Science, University of Zagreb, Republic of Croatia
Proper citation: RRID:RGD_9831158 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=7800692
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Live Animals; Cryopreserved Embryo
Alternate IDs: 7800692
Notes: MKO rat is derived from Wistar male rat which exhibited large-size and abnormal lipid metabolism. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_7800692 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=8553015
Source Database: Rat Genome Database (RGD)
Genetic Background: inbred
Availability: Unknown
Alternate IDs: 8553015
Notes: To Animal Resources Centre from Charles River Animal Resources Centre, Australia
Proper citation: RRID:RGD_8553015 Copy
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