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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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129S1.129P2(Cg)-Zfa-pstm1Ems/Mmnc Resource Report Resource Website |
RRID:MMRRC_000355-UNC | Mus musculus | Research areas: Cell Biology, Developmental Biology, Reproduction; Mutation Type: Targeted Mutation ; Collection: | Zfa-ps | 000355-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12906850 | MMRRC_355-UNC, MMRRC_000355, MMRRC_355 | 2026-08-01 05:32:13 | 0 | ||||
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B6.129-Tcrbtm1Mom Ifngtm1Ts/Mmnc Resource Report Resource Website Issue |
RRID:MMRRC_000337-UNC | Mus musculus | Research areas: Cancer, Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | enlarged liver [MP:0000599]| enlarged spleen [MP:0000691]| spleen hypoplasia [MP:0000694]| absent CD8-positive [MP:0000727]| alpha-beta T cells [MP:0000938]| motor neuron degeneration [MP:0001219]| thick epidermis [MP:0001243]| abnormal dermal layer morphology [MP:0001263]| weight loss [MP:0001805]| decreased IgG level [MP:0001807]| decreased IgA level [MP:0001823]| thymus hypoplasia [MP:0001825]| arrested T cell differentiation [MP:0002023]| increased B cell derived lymphoma incidence [MP:0002083]| premature death [MP:0002132]| abnormal respiratory system morphology [MP:0002133]| abnormal respiratory system physiology [MP:0002144]| abnormal B cell differentiation [MP:0002492]| decreased IgE level [MP:0002494]| increased IgM level [MP:0002495]| increased IgA level [MP:0002816]| colitis [MP:0003691]| abnormal microglial cell physiology [MP:0003725]| increased autoantibody level [MP:0003726]| decreased autoantibody level [MP:0003790]| absent CD4-positive [MP:0004762]| alpha beta T cells [MP:0004796]| increased anti-double stranded DNA antibody level [MP:0004829]| increased anti-histone antibody level [MP:0004939]| increased anti-chromatin antibody level [MP:0004947]| abnormal B cell morphology [MP:0005014]| skin inflammation [MP:0005015]| increased B cell number [MP:0005016]| increased T cell number [MP:0005017]| decreased lymphocyte cell number [MP:0005018]| decreased B cell number [MP:0005025]| decreased T cell number [MP:0005092]| abnormal response to infection [MP:0008075]| decreased double-positive T cell number [MP:0008079]| decreased CD4-positive [MP:0008098]| alpha beta T cell number [MP:0008173]| decreased CD8-positive [MP:0008181]| alpha-beta T cell number [MP:0008188]| decreased plasma cell number [MP:0008210]| increased follicular B cell number [MP:0008214]| increased marginal zone B cell number [MP:0008495]| abnormal transitional stage B cell morphology [MP:0009925]| increased mature B cell number [MP:0010229]| increased immature B cell number [MP:0010286]| decreased IgG1 level [MP:0011320]| increased transitional stage T2 B cell number [MP:0011427]| increased transitional stage T3 B cell number [MP:0020519]| increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466] | |Tcrb||Ifngr2 | 000337-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:1359428 PMID:11705890 |
MMRRC_337-UNC, MMRRC_000337, MMRRC_337 | 2026-08-01 05:32:13 | 0 | |||
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B6.Cg-Tcrdtm1Mom Tg(UBC-GFP)30Scha/Mmnc Resource Report Resource Website |
RRID:MMRRC_000340-UNC | Mus musculus | Research areas: Cancer, Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | enlarged liver [MP:0000599]| enlarged spleen [MP:0000691]| spleen hypoplasia [MP:0000694]| absent CD8-positive [MP:0000727]| alpha-beta T cells [MP:0001191]| abnormal skin condition [MP:0001194]| dermatitis [MP:0001805]| decreased IgG level [MP:0001807]| decreased IgA level [MP:0001823]| thymus hypoplasia [MP:0001825]| arrested T cell differentiation [MP:0002023]| increased B cell derived lymphoma incidence [MP:0002024]| increased T cell derived lymphoma incidence [MP:0002083]| premature death [MP:0002132]| abnormal respiratory system morphology [MP:0002133]| abnormal respiratory system physiology [MP:0002407]| abnormal double-negative T cell morphology [MP:0002492]| decreased IgE level [MP:0002494]| increased IgM level [MP:0002495]| increased IgA level [MP:0002796]| impaired skin barrier function [MP:0002816]| colitis [MP:0003306]| small intestinal inflammation [MP:0003725]| increased autoantibody level [MP:0003726]| decreased autoantibody level [MP:0003790]| absent CD4-positive [MP:0004762]| alpha beta T cells [MP:0004796]| increased anti-double stranded DNA antibody level [MP:0004829]| increased anti-histone antibody level [MP:0005014]| increased anti-chromatin antibody level [MP:0005015]| increased B cell number [MP:0005016]| increased T cell number [MP:0005018]| decreased lymphocyte cell number [MP:0005025]| decreased T cell number [MP:0005092]| abnormal response to infection [MP:0005617]| decreased double-positive T cell number [MP:0006042]| increased susceptibility to type IV hypersensitivity reaction [MP:0008098]| increased apoptosis [MP:0008173]| decreased plasma cell number [MP:0008181]| increased follicular B cell number [MP:0008188]| increased marginal zone B cell number [MP:0008210]| abnormal transitional stage B cell morphology [MP:0008214]| increased mature B cell number [MP:0008348]| increased immature B cell number [MP:0008356]| absent gamma-delta T cells [MP:0008495]| abnormal gamma-delta T cell differentiation [MP:0008757]| decreased IgG1 level [MP:0009925]| abnormal T cell receptor gamma chain V-J recombination [MP:0010229]| increased transitional stage T2 B cell number [MP:0010286]| increased transitional stage T3 B cell number [MP:0011320]| increased plasmacytoma incidence [MP:0011427]| abnormal glomerular capillary morphology [MP:0020519] | |Tcrd|Ubc|GFP| | 000340-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:8361537 | MMRRC_340-UNC, MMRRC_000340, MMRRC_34 | 2026-08-01 05:32:05 | 0 | |||
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STOCK Pdx1tm2Cvw/Mmnc Resource Report Resource Website |
RRID:MMRRC_000434-UNC | Mus musculus | Research areas: Diabetes, Endocrine Deficiency; Mutation Type: Targeted Mutation ; Collection: BCBC-Beta Cell Biology Consortium | sparse hair [MP:0000416]| abnormal stomach morphology [MP:0000470]| abnormal foregut morphology [MP:0000474]| abnormal intestine morphology [MP:0000477]| abnormal small intestine morphology [MP:0000496]| abnormal liver development [MP:0000596]| thin skin [MP:0001199]| decreased body weight [MP:0001262]| dehydration [MP:0001429]| postnatal growth retardation [MP:0001732]| increased glucagon secretion [MP:0002710]| decreased circulating insulin level [MP:0002727]| abnormal bile duct development [MP:0002929]| decreased insulin secretion [MP:0003059]| abnormal duodenum morphology [MP:0003271]| exocrine pancreatic insufficiency [MP:0003335]| abnormal pancreatic beta cell physiology [MP:0003562]| absent pancreas [MP:0003655]| abnormal pancreas development [MP:0003934]| abnormal enteroendocrine cell morphology [MP:0004141]| abnormal pancreatic islet morphology [MP:0005215]| impaired glucose tolerance [MP:0005293]| pancreatic islet hyperplasia [MP:0005491]| increased circulating glucose level [MP:0005559]| abnormal mitochondrial physiology [MP:0006036]| abnormal pancreatic duct morphology [MP:0009143]| abnormal pancreatic acinar cell morphology [MP:0009146]| abnormal pancreatic beta cell differentiation [MP:0009175]| distended stomach [MP:0009511]| abnormal pyloric sphincter morphology [MP:0009861]| abnormal stomach pyloric region morphology [MP:0010785]| abnormal stomach enteroendocrine cell morphology [MP:0010803]| abnormal tricarboxylic acid cycle [MP:0010958]| postnatal lethality [MP:0011085]| complete penetrance [MP:0014125] | Pdx1 | 000434-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:8631275 | MMRRC_434-UNC, MMRRC_000434, MMRRC_434 | 2026-08-01 05:32:06 | 0 | |||
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B6.129X1-Ly6atm1Grau/Mmnc Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000383-UNC | Mus musculus | Research areas: Cancer, Cardiovascular, Cell Biology, Dermatology, Developmental Biology, Hematology, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection: | no abnormal phenotype detected [MP:0002169] | Ly6a | 000383-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12591281 PMID:11969254 |
MMRRC_383-UNC, MMRRC_000383, MMRRC_383 | 2026-08-01 05:32:06 | 1 | |||
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B6.129S1-Slc6a1tm1Lst/Mmucd Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000426-UCD | Mus musculus | Research areas: Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection: | abnormal inhibitory postsynaptic currents [MP:0002945]| abnormal neurotransmitter uptake [MP:0003444]| abnormal neurotransmitter secretion [MP:0005445] | Slc6a1 | 000426-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12815026 PMID:12451126 |
MMRRC_426-UCD, MMRRC_000426, MMRRC_426 | 2026-08-01 05:32:13 | 3 | |||
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B6.129S7-Chrna5tm1Mdb Chrnb4tm1Mdb/Mmmh Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000442-MU | Mus musculus | Research areas: Cardiovascular, Neurobiology, Research Tools; Mutation Type: Targeted Mutation ; Collection: | delayed ear emergence [MP:0000054]| delayed hair appearance [MP:0000422]| abnormal urinary bladder morphology [MP:0000538]| distended urinary bladder [MP:0000539]| abnormal urinary bladder urothelium morphology [MP:0000540]| postnatal growth retardation [MP:0001732]| increased susceptibility to bacterial infection [MP:0002412]| mydriasis [MP:0002546]| decreased susceptibility to pharmacologically induced seizures [MP:0002887]| urinary incontinence [MP:0003280]| intestinal hypoperistalsis [MP:0003290]| abnormal single cell response [MP:0003463]| eyelids fail to open [MP:0005176]| narrow eye opening [MP:0005287]| impaired pupillary reflex [MP:0006243]| abnormal autonomic nervous system physiology [MP:0006276]| urinary bladder inflammation [MP:0009646]| abnormal urinary bladder physiology [MP:0010386]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011625]| decreased susceptibility to pharmacologically induced seizures [MP:0002887] | |Chrnb4||Chrna5 | 000442-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:14996991 | MMRRC_442-MU, MMRRC_000442, MMRRC_442 | 2026-08-01 05:32:06 | 1 | |||
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129S6-Nrcamtm1Gmt/Mmucd Resource Report Resource Website |
RRID:MMRRC_000370-UCD | Mus musculus | Research areas: Cell Biology, Developmental Biology, Models for Human Disease, Neurobiology, Research Tools, Sensorineural; Mutation Type: Targeted Mutation ; Collection: | paralysis [MP:0000753]| small cerebellum [MP:0000852]| abnormal cerebellum development [MP:0000854]| abnormal cerebellar foliation [MP:0000857]| abnormal cerebellum external granule cell layer morphology [MP:0000872]| abnormal cerebellar granule layer morphology [MP:0000886]| decreased body weight [MP:0001262]| abnormal social investigation [MP:0001360]| ataxia [MP:0001393]| abnormal spatial learning [MP:0001463]| abnormal learning/memory/conditioning [MP:0002063]| postnatal lethality [MP:0002082]| decreased vertical activity [MP:0002757]| abnormal motor learning [MP:0002804]| abnormal locomotor activation [MP:0003313]| abnormal cerebellar cortex morphology [MP:0004097]| abnormal axon morphology [MP:0005404]| abnormal neurite morphology [MP:0008415]| decreased nerve conduction velocity [MP:0008814]| decreased prepulse inhibition [MP:0009142]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011086] | Nrcam | 000370-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:11564762 PMID:14602817 |
MMRRC_370-UCD, MMRRC_000370, MMRRC_37 | 2026-08-01 05:32:13 | 0 | |||
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B6.129-Sgcatm1Kcam/Mmmh Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000425-MU | Mus musculus | Research areas: Cardiovascular, Developmental Biology, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection: | dystrophic muscle [MP:0000752]| heart inflammation [MP:0001853]| abnormal skeletal muscle fiber morphology [MP:0003084]| cardiac fibrosis [MP:0003141]| calcified muscle [MP:0003199]| abnormal heart left ventricle morphology [MP:0003921]| abnormal muscle fiber morphology [MP:0004087]| abnormal sarcolemma morphology [MP:0004121]| decreased cardiac muscle contractility [MP:0005140]| cardiomyopathy [MP:0005330]| abnormal muscle contractility [MP:0005620]| centrally nucleated skeletal muscle fibers [MP:0009404]| increased extensor digitorum longus weight [MP:0009423]| increased soleus weight [MP:0009425]| increased circulating creatine kinase level [MP:0010090]| abnormal circulating pyruvate kinase level [MP:0010106]| cardiac muscle necrosis [MP:0010632] | Sgca | 000425-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:9744877 PMID:12855815 PMID:10981665 |
MMRRC_425-MU, MMRRC_000425, MMRRC_425 | 2026-08-01 05:32:06 | 1 | |||
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B6.Cg-Tcrbtm1Mom Tg(UBC-GFP)30Scha/Mmnc Resource Report Resource Website |
RRID:MMRRC_000339-UNC | Mus musculus | Research areas: Cancer, Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | enlarged liver [MP:0000599]| enlarged spleen [MP:0000691]| spleen hypoplasia [MP:0000694]| absent CD8-positive [MP:0000727]| alpha-beta T cells [MP:0000938]| motor neuron degeneration [MP:0001219]| thick epidermis [MP:0001243]| abnormal dermal layer morphology [MP:0001263]| weight loss [MP:0001805]| decreased IgG level [MP:0001807]| decreased IgA level [MP:0001823]| thymus hypoplasia [MP:0001825]| arrested T cell differentiation [MP:0002023]| increased B cell derived lymphoma incidence [MP:0002083]| premature death [MP:0002132]| abnormal respiratory system morphology [MP:0002133]| abnormal respiratory system physiology [MP:0002144]| abnormal B cell differentiation [MP:0002492]| decreased IgE level [MP:0002494]| increased IgM level [MP:0002495]| increased IgA level [MP:0002816]| colitis [MP:0003691]| abnormal microglial cell physiology [MP:0003725]| increased autoantibody level [MP:0003726]| decreased autoantibody level [MP:0003790]| absent CD4-positive [MP:0004762]| alpha beta T cells [MP:0004796]| increased anti-double stranded DNA antibody level [MP:0004829]| increased anti-histone antibody level [MP:0004939]| increased anti-chromatin antibody level [MP:0004947]| abnormal B cell morphology [MP:0005014]| skin inflammation [MP:0005015]| increased B cell number [MP:0005016]| increased T cell number [MP:0005017]| decreased lymphocyte cell number [MP:0005018]| decreased B cell number [MP:0005025]| decreased T cell number [MP:0005092]| abnormal response to infection [MP:0008075]| decreased double-positive T cell number [MP:0008079]| decreased CD4-positive [MP:0008098]| alpha beta T cell number [MP:0008173]| decreased CD8-positive [MP:0008181]| alpha-beta T cell number [MP:0008188]| decreased plasma cell number [MP:0008210]| increased follicular B cell number [MP:0008214]| increased marginal zone B cell number [MP:0008495]| abnormal transitional stage B cell morphology [MP:0009925]| increased mature B cell number [MP:0010229]| increased immature B cell number [MP:0010286]| decreased IgG1 level [MP:0011320]| increased transitional stage T2 B cell number [MP:0011427]| increased transitional stage T3 B cell number [MP:0020519] | |Tcrb|Ubc|GFP| | 000339-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:1359428 | MMRRC_339-UNC, MMRRC_000339, MMRRC_339 | 2026-08-01 05:32:05 | 0 | |||
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B6.129X1-Trp53tm1Ldo/Mmnc Resource Report Resource Website |
RRID:MMRRC_000362-UNC | Mus musculus | Research areas: Cancer; Mutation Type: Targeted Mutation ; Collection: | decreased bone mineral density [MP:0000063]| kyphosis [MP:0000160]| lordosis [MP:0000162]| sparse hair [MP:0000416]| delayed hair regrowth [MP:0000423]| liver hypoplasia [MP:0000600]| abnormal mammary gland development [MP:0000628]| spleen hypoplasia [MP:0000694]| thin dermal layer [MP:0001244]| weight loss [MP:0001263]| testis hypoplasia [MP:0001940]| increased tumor incidence [MP:0002020]| increased T cell derived lymphoma incidence [MP:0002024]| increased sarcoma incidence [MP:0002032]| increased lung adenoma incidence [MP:0002048]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| muscular atrophy [MP:0002269]| delayed wound healing [MP:0002908]| decreased liver weight [MP:0003402]| renal hypoplasia [MP:0003446]| premature aging [MP:0003786]| decreased kidney weight [MP:0003918]| decreased circulating insulin-like growth factor I level [MP:0004701]| decreased skeletal muscle mass [MP:0004819]| decreased testis weight [MP:0004852]| decreased spleen weight [MP:0004953]| lethargy [MP:0005202]| abnormal cell physiology [MP:0005621]| decreased subcutaneous adipose tissue amount [MP:0008844]| abnormal physiological response to xenobiotic [MP:0008872]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009766] | Trp53 | 000362-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:11780111 | MMRRC_362-UNC, MMRRC_000362, MMRRC_362 | 2026-08-01 05:32:13 | 0 | |||
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B6;129X1-Ptk2tm1Lfr/Mmucd Resource Report Resource Website 1+ mentions |
RRID:MMRRC_009967-UCD | Mus musculus | Research areas: Apoptosis, Cancer, Cardiovascular, Cell Biology, Dermatology, Developmental Biology, Hematology, Immunology and Inflammation, Models for Human Disease, Neurobiology, Sensorineural; Mutation Type: Targeted Mutation ; Collection: | abnormal vascular regression [MP:0000364]| decreased hair follicle number [MP:0000379]| abnormal hair follicle orientation [MP:0000383]| sparse hair [MP:0000416]| abnormal hair cycle [MP:0000427]| decreased thymocyte number [MP:0000715]| thin epidermis [MP:0001218]| abnormal blood vessel morphology [MP:0001614]| decreased embryo size [MP:0001698]| disorganized yolk sac vascular plexus [MP:0001723]| hemorrhage [MP:0001914]| abnormal T cell differentiation [MP:0002145]| abnormal vitelline vasculature morphology [MP:0003229]| abnormal capillary morphology [MP:0003658]| decreased double-positive T cell number [MP:0005092]| decreased angiogenesis [MP:0005602]| abnormal vascular endothelial cell morphology [MP:0006055]| decreased keratinocyte proliferation [MP:0009584]| embryonic lethality during organogenesis [MP:0011098]| complete penetrance [MP:0013192]| decreased sebaceous gland number [MP:0013585] | Ptk2 | 009967-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:14642275 | MMRRC_9967-UCD, MMRRC_009967, MMRRC_9967 | 2026-08-01 05:35:30 | 9 | |||
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STOCK Htr3atm1Ckn/Mmucd Resource Report Resource Website |
RRID:MMRRC_009966-UCD | Mus musculus | Research areas: Models for Human Disease; Mutation Type: Targeted Mutation ; Collection: | increased bone marrow cell number [MP:0000321]| hydronephrosis [MP:0000519]| abnormal urinary bladder morphology [MP:0000538]| distended urinary bladder [MP:0000539]| abnormal urinary bladder urothelium morphology [MP:0000540]| abnormal urination pattern [MP:0001761]| kidney inflammation [MP:0001859]| premature death [MP:0002083]| increased urine protein level [MP:0002962]| urinary incontinence [MP:0003280]| prostate gland inflammation [MP:0003608]| decreased lymphocyte cell number [MP:0005016]| cachexia [MP:0005150]| neurogenic bladder [MP:0005302]| increased blood urea nitrogen level [MP:0005565]| urinary bladder obstruction [MP:0009552]| abnormal urinary bladder physiology [MP:0010386]| pyelonephritis [MP:0011403]| tubulointerstitial nephritis [MP:0011405]| abnormal urinary bladder detrusor smooth muscle morphology [MP:0011774]| abnormal male prostatic urethra morphology [MP:0011777]| abnormal urinary bladder neck morphology [MP:0011784]| increased urinary bladder weight [MP:0011799]| urethra obstruction [MP:0011801]| seminal vesiculitis [MP:0011802] | Htr3a | 009966-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:15201326 PMID:9635195 |
MMRRC_9966-UCD, MMRRC_009966, MMRRC_9966 | 2026-08-01 05:35:29 | 0 | |||
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B6;129X1-Abca1tm2Jp/Mmmh Resource Report Resource Website |
RRID:MMRRC_009999-MU | Mus musculus | Research areas: Cardiovascular, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection: | abnormal circulating cholesterol level [MP:0000180]| decreased circulating HDL cholesterol level [MP:0000186]| abnormal kidney physiology [MP:0002136]| decreased circulating phospholipid level [MP:0003981]| abnormal circulating protein level [MP:0005416] | Abca1 | 009999-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:16024913 | MMRRC_9999-MU, MMRRC_009999, MMRRC_9999 | 2026-08-01 05:35:29 | 0 | |||
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B6.129-Cacna1htm1Kcam/Mmmh Resource Report Resource Website 1+ mentions |
RRID:MMRRC_009979-MU | Mus musculus | Research areas: Cardiovascular, Cell Biology, Models for Human Disease, Neurobiology, Reproduction; Mutation Type: Targeted Mutation ; Collection: | abnormal cartilage development [MP:0000164]| abnormal myocardial fiber morphology [MP:0000278]| decreased body size [MP:0001265]| abnormal vocalization [MP:0001529]| abnormal blood vessel morphology [MP:0001614]| abnormal cardiovascular system morphology [MP:0002127]| increased vasoconstriction [MP:0003025]| abnormal tracheal cartilage morphology [MP:0003120]| cardiac fibrosis [MP:0003141]| abnormal channel response [MP:0003484]| abnormal arteriole morphology [MP:0004112]| trachea stenosis [MP:0010883] | Cacna1h | 009979-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:14631046 | MMRRC_9979-MU, MMRRC_009979, MMRRC_9979 | 2026-08-01 05:35:30 | 5 | |||
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B6.129P2-Terttm1Leah/Mmucd Resource Report Resource Website 1+ mentions |
RRID:MMRRC_010432-UCD | Mus musculus | Research areas: Cancer, Models for Human Disease; Mutation Type: Targeted Mutation ; Collection: | abnormal telomere length [MP:0003155]| aneuploidy [MP:0004024]| abnormal cell physiology [MP:0005621]| chromosomal instability [MP:0008866] | Tert | 010432-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:11102810 PMID:11904422 PMID:15079066 |
MMRRC_10432-UCD, MMRRC_010432, MMRRC_1432 | 2026-08-01 05:35:37 | 1 | |||
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B6;129-Btrctm1Paga/Mmnc Resource Report Resource Website |
RRID:MMRRC_010480-UNC | Mus musculus | Research areas: Cancer, Cell Biology; Mutation Type: Targeted Mutation ; Collection: | abnormal enterocyte morphology [MP:0000479]| abnormal intestinal epithelium morphology [MP:0000488]| abnormal colon morphology [MP:0000495]| abnormal intestinal mucosa morphology [MP:0000511]| intestinal inflammation [MP:0001858]| reduced male fertility [MP:0001922]| premature death [MP:0002083]| oligozoospermia [MP:0002687]| rectal hemorrhage [MP:0003293]| abnormal mitosis [MP:0004046]| abnormal large intestine crypts of Lieberkuhn morphology [MP:0004842]| diarrhea [MP:0005036]| abnormal male meiosis [MP:0005169]| increased circulating interleukin-1 beta level [MP:0008641]| chromosomal instability [MP:0008866]| abnormal mitotic spindle morphology [MP:0009760]| abnormal meiotic spindle morphology [MP:0009761] | Btrc | 010480-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12791266 PMID:15340078 |
MMRRC_10480-UNC, MMRRC_010480, MMRRC_148 | 2026-08-01 05:35:32 | 0 | |||
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B6;129-Erbb4tm1Fej/Mmucd Resource Report Resource Website 1+ mentions |
RRID:MMRRC_010439-UCD | Mus musculus | Research areas: Cancer, Cardiovascular, Models for Human Disease, Neurobiology, Research Tools; Mutation Type: Targeted Mutation ; Collection: | abnormal mammary gland development [MP:0000628]| abnormal myelination [MP:0000920]| hyperactivity [MP:0001399]| abnormal lactation [MP:0001882]| enhanced long term potentiation [MP:0003008]| abnormal mammary gland growth during lactation [MP:0006270]| decreased prepulse inhibition [MP:0009142]| postnatal lethality [MP:0011085] | Erbb4 | 010439-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12954715 PMID:15219717 |
MMRRC_10439-UCD, MMRRC_010439, MMRRC_1439 | 2026-08-01 05:35:31 | 8 | |||
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B6.129S1-Uchl3tm1Tilg/Mmmh Resource Report Resource Website |
RRID:MMRRC_010587-MU | Mus musculus | Research areas: Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection: | paralysis [MP:0000753]| abnormal dorsal root ganglion morphology [MP:0000961]| decreased body weight [MP:0001262]| retinal degeneration [MP:0001326]| ataxia [MP:0001393]| abnormal gait [MP:0001406]| premature death [MP:0002083]| abnormal retinal vasculature morphology [MP:0002792]| abnormal skeletal muscle fiber morphology [MP:0003084]| dysphagia [MP:0003158]| axonal dystrophy [MP:0003225]| abnormal retinal layer morphology [MP:0003727]| abnormal photoreceptor outer segment morphology [MP:0003729]| abnormal photoreceptor inner segment morphology [MP:0003730]| abnormal retinal outer nuclear layer morphology [MP:0003731]| axon degeneration [MP:0005405]| thin retinal outer nuclear layer [MP:0008515]| thin retinal outer plexiform layer [MP:0008519]| increased retinal apoptosis [MP:0030005] | Uchl3 | 010587-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:10713173 PMID:11555633 PMID:15884048 |
MMRRC_10587-MU, MMRRC_010587, MMRRC_1587 | 2026-08-01 05:35:41 | 0 | |||
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Izon ES cell line Sh3gl2 Resource Report Resource Website |
RRID:MMRRC_010599-UCD | Mus musculus | Research areas: Developmental Biology, Neurobiology, Research Tools; Mutation Type: Targeted Mutation ; Collection: | Sh3gl2 | 010599-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | MMRRC_10599-UCD, MMRRC_010599, MMRRC_1599 | 2026-08-01 05:35:41 | 0 |
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