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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://www.jax.org/strain/038643
Source Database: JAX Mice and Services
Affected Genes: deletion; Chr 12; Melody Zeng 1
Genomic Alteration: deletion; Chr 12; Melody Zeng 1
Availability: live
Notes: gene symbol note: deletion; Chr 12; Melody Zeng 1; coisogenic strain|mutant strain: Del(12Ighg3-Ighg2b)1Mzeng
Proper citation: RRID:IMSR_JAX:038643 Copy
https://www.jax.org/strain/038629
Source Database: JAX Mice and Services
Affected Genes: gene trap ROSA 26; Philippe Soriano|platelet derived growth factor receptor; beta polypeptide
Genomic Alteration: targeted mutation 65.2; Hongkui Zeng|targeted mutation 1.1; Lorin E Olson
Availability: live
Notes: gene symbol note: gene trap ROSA 26; Philippe Soriano|platelet derived growth factor receptor; beta polypeptide; mutant stock: Gt(ROSA)26Sor|Pdgfrb
Proper citation: RRID:IMSR_JAX:038629 Copy
https://www.jax.org/strain/038749
Source Database: JAX Mice and Services
Affected Genes: collagen; type I; alpha 1|gene trap ROSA 26; Philippe Soriano|reverse tetracycline-controlled transactivator
Genomic Alteration: targeted mutation 5; Fernando Camargo|targeted mutation 1; Rudolf Jaenisch
Availability: live
Synonyms: Cas9-TdT-gRNAs-M2
Notes: gene symbol note: collagen; type I; alpha 1|gene trap ROSA 26; Philippe Soriano|reverse tetracycline-controlled transactivator; mutant stock: Col1a1|Gt(ROSA)26Sor|rtTA
Proper citation: RRID:IMSR_JAX:038749 Copy
https://www.jax.org/strain/038560
Source Database: JAX Mice and Services
Affected Genes: prion protein readthrough transcript|presenilin 1|amyloid beta precursor protein|transgene insertion 85; David R Borchelt
Genomic Alteration: transgene insertion 85; David R Borchelt
Availability: live
Notes: gene symbol note: prion protein readthrough transcript|presenilin 1|amyloid beta precursor protein|transgene insertion 85; David R Borchelt; wild-derived inbred strain|mutant strain|congenic strain: Prn|PSEN1|APP|Tg(APPswe;PSEN1dE9)85Dbo
Proper citation: RRID:IMSR_JAX:038560 Copy
https://www.jax.org/strain/038824
Source Database: JAX Mice and Services
Affected Genes: myosin; heavy polypeptide 11; smooth muscle
Genomic Alteration: endonuclease-mediated mutation 2; Jifeng Zhang
Availability: live
Notes: gene symbol note: myosin; heavy polypeptide 11; smooth muscle; coisogenic strain|mutant strain: Myh11
Proper citation: RRID:IMSR_JAX:038824 Copy
https://www.jax.org/strain/039001
Source Database: JAX Mice and Services
Affected Genes: CD47 antigen (Rh-related antigen; integrin-associated signal transducer)|interleukin 2 receptor; gamma chain|N-sulfoglucosamine sulfohydrolase (sulfamidase)|recombination activating gene 2
Genomic Alteration: targeted mutation 1; Frederik P Lindberg|targeted mutation 1; Warren J Leonard|mucopolysaccharidosis IIIA|targeted mutation 1; Frederick W Alt
Availability: live
Notes: gene symbol note: CD47 antigen (Rh-related antigen; integrin-associated signal transducer)|interleukin 2 receptor; gamma chain|N-sulfoglucosamine sulfohydrolase (sulfamidase)|recombination activating gene 2; mutant strain|congenic strain: Cd47|Il2rg|Sgsh|Rag2
Proper citation: RRID:IMSR_JAX:039001 Copy
https://www.jax.org/strain/038919
Source Database: JAX Mice and Services
Affected Genes: interspecies replacement; human Chr 19; Michael Koob 2
Genomic Alteration: interspecies replacement; human Chr 19; Michael Koob 2
Availability: live
Synonyms: B6J.B6N-Tc(HSA19*APOE_i4)1Mdk/J
Notes: gene symbol note: interspecies replacement; human Chr 19; Michael Koob 2; mutant strain|congenic strain: Isr(HSA19;APOE_i4)2Mdk
Proper citation: RRID:IMSR_JAX:038919 Copy
https://www.jax.org/strain/038812
Source Database: JAX Mice and Services
Affected Genes: coagulation factor XII (Hageman factor)
Genomic Alteration: targeted mutation 1; Francis J Castellino
Availability: live
Notes: gene symbol note: coagulation factor XII (Hageman factor); mutant strain|congenic strain: F12
Proper citation: RRID:IMSR_JAX:038812 Copy
https://www.jax.org/strain/038813
Source Database: JAX Mice and Services
Affected Genes: fibrinogen gamma chain
Genomic Alteration: targeted mutation 1; Francis J Castellino
Availability: live
Notes: gene symbol note: fibrinogen gamma chain; mutant strain|congenic strain: Fgg
Proper citation: RRID:IMSR_JAX:038813 Copy
https://www.jax.org/strain/038929
Source Database: JAX Mice and Services
Affected Genes: retinoic acid receptor; beta|retinoid X receptor gamma
Genomic Alteration: endonuclease-mediated mutation 1; Nenad Sestan
Availability: live
Notes: gene symbol note: retinoic acid receptor; beta|retinoid X receptor gamma; mutant stock: Rarb|Rxrg
Proper citation: RRID:IMSR_JAX:038929 Copy
https://www.jax.org/strain/039033
Source Database: JAX Mice and Services
Affected Genes: HtrA serine peptidase 1
Genomic Alteration: targeted mutation 1.2; Josephine Hoh
Availability: live
Notes: gene symbol note: HtrA serine peptidase 1; coisogenic strain|mutant strain: Htra1
Proper citation: RRID:IMSR_JAX:039033 Copy
https://www.jax.org/strain/039032
Source Database: JAX Mice and Services
Affected Genes: HtrA serine peptidase 2
Genomic Alteration: targeted mutation 1.1; Josephine Hoh
Availability: live
Notes: gene symbol note: HtrA serine peptidase 2; coisogenic strain|mutant strain: Htra2
Proper citation: RRID:IMSR_JAX:039032 Copy
https://www.jax.org/strain/038908
Source Database: JAX Mice and Services
Affected Genes: amyloid beta precursor protein|interspecies replacement; human Chr 17; Michael Koob 2
Genomic Alteration: endonuclease-mediated mutation 1; MODEL-AD Center|interspecies replacement; human Chr 17; Michael Koob 2
Availability: live
Synonyms: B6.Cg-Tc(HSA17)2Mdk App
Notes: gene symbol note: amyloid beta precursor protein|interspecies replacement; human Chr 17; Michael Koob 2; mutant strain|congenic strain: App|Isr(HSA17)2Mdk
Proper citation: RRID:IMSR_JAX:038908 Copy
https://www.jax.org/strain/039199
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 4.2.28; Myriam Hemberger
Genomic Alteration: transgene insertion 4.2.28; Myriam Hemberger
Availability: live
Synonyms: B6N.Cg-Tg(Sox2-flpo)4.2.28Mhem/J
Notes: gene symbol note: transgene insertion 4.2.28; Myriam Hemberger; mutant strain: Tg(Sox2-flpo)4.2.28Mhem
Proper citation: RRID:IMSR_JAX:039199 Copy
https://www.jax.org/strain/039055
Source Database: JAX Mice and Services
Affected Genes: histocompatibility 2; D region locus 1|major histocompatibility complex; class II; DQ alpha 1|protein kinase; DNA activated; catalytic polypeptide|transgene insertion 1; Chella David|interleukin 2 receptor; gamma chain|histocompatibility 2; class II antigen A; beta 1|histocompatibility 2; K1; K region|major histocompatibility complex; class II; DQ beta 1
Genomic Alteration: endonuclease-mediated mutation 5; David V Serreze|transgene insertion 1; Chella David|severe combined immunodeficiency|targeted mutation 1; Warren J Leonard|endonuclease-mediated mutation 1; Jackson|endonuclease-mediated mutation 1; David V Serreze
Availability: live
Notes: gene symbol note: histocompatibility 2; D region locus 1|major histocompatibility complex; class II; DQ alpha 1|protein kinase; DNA activated; catalytic polypeptide|transgene insertion 1; Chella David|interleukin 2 receptor; gamma chain|histocompatibility 2; class II antigen A; beta 1|histocompatibility 2; K1; K region|major histocompatibility complex; class II; DQ beta 1; mutant strain|congenic strain: H2-D1|HLA-DQA1|Prkdc|Tg(HLA-DQA1;HLA-DQB1)1Dv|Il2rg|H2-Ab1|H2-K1|HLA-DQB1
Proper citation: RRID:IMSR_JAX:039055 Copy
https://www.jax.org/strain/039172
Source Database: JAX Mice and Services
Affected Genes: interspecies replacement; human Chr 6; Michael Koob 1
Genomic Alteration: interspecies replacement; human Chr 6; Michael Koob 1
Availability: live
Synonyms: C57BL/6-Tc(HSA6)1Mdk/J
Notes: gene symbol note: interspecies replacement; human Chr 6; Michael Koob 1; mutant strain: Isr(HSA6)1Mdk
Proper citation: RRID:IMSR_JAX:039172 Copy
https://www.jax.org/strain/039175
Source Database: JAX Mice and Services
Affected Genes: presenilin 1|amyloid beta precursor protein|interspecies replacement; human Chr 17; Michael Koob 1
Genomic Alteration: targeted mutation 1.1; Michael D Koob|interspecies replacement; human Chr 17; Michael Koob 1
Availability: live
Synonyms: B6J.B6N(CBA)-Tc(HSA17)1Mdk Psen1
Notes: gene symbol note: presenilin 1|amyloid beta precursor protein|interspecies replacement; human Chr 17; Michael Koob 1; mutant strain|congenic strain: Psen1|App|Isr(HSA17)1Mdk
Proper citation: RRID:IMSR_JAX:039175 Copy
https://www.jax.org/strain/039108
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 2; Eva M Eicher|sex determining region of Chr Y
Genomic Alteration: transgene insertion 2; Eva M Eicher|sex determining region of Chr Y-deletion 1; Robin Lovell-Badge
Availability: live
Notes: gene symbol note: transgene insertion 2; Eva M Eicher|sex determining region of Chr Y; mutant strain|congenic strain: Tg(Sry)2Ei|Sry
Proper citation: RRID:IMSR_JAX:039108 Copy
https://www.jax.org/strain/039039
Source Database: JAX Mice and Services
Affected Genes: crystallin; gamma C
Genomic Alteration: mutation 2 Jackson
Availability: live
Notes: gene symbol note: crystallin; gamma C; mutant strain: Crygc
Proper citation: RRID:IMSR_JAX:039039 Copy
https://www.jax.org/strain/039168
Source Database: JAX Mice and Services
Affected Genes: synuclein; alpha
Genomic Alteration: targeted mutation 3.1; Michael D Koob
Availability: live
Notes: gene symbol note: synuclein; alpha; mutant strain|congenic strain: Snca
Proper citation: RRID:IMSR_JAX:039168 Copy
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