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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00007939
Source Database: WormBase (WB)
Affected Genes: WBGene00010868(somi-1)
Genomic Alteration: WBGene00010868(somi-1)
Availability: available
Source References: EMPTY
Synonyms: somi-1(tm562) V.
Alternate IDs: WB-STRAIN:GR1586, CGC_GR1586
Notes: Adults slightly Dpy. Suppresses defects caused by over-expression of mir-84. Enhances retarded heterchronic phenotypes caused by a weak allele of let-7 or loss of mir-84. Reference: Hayes GD, Riedel CG, Ruvkun G. 2011. Genes Dev. 2011 Oct 1;25(19):2079-92.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00007939 Copy
http://www.wormbase.org/db/get?name=WBStrain00007938
Source Database: WormBase (WB)
Affected Genes: WBGene00010868(somi-1)
Genomic Alteration: WBGene00010868(somi-1)
Availability: available
Source References: EMPTY
Synonyms: somi-1(mg415) V.
Alternate IDs: WB-STRAIN:GR1583, CGC_GR1583
Notes: Adults slightly Dpy. Suppresses defects caused by over-expression of mir-84. Enhances retarded heterchronic phenotypes caused by a weak allele of let-7 or loss of mir-84. Reference: Hayes GD, Riedel CG, Ruvkun G. 2011. Genes Dev. 2011 Oct 1;25(19):2079-92.
Proper citation: RRID:WB-STRAIN:WBStrain00007938 Copy
http://www.wormbase.org/db/get?name=WBStrain00007937
Source Database: WormBase (WB)
Affected Genes: WBGene00000920(daf-28)
Genomic Alteration: WBGene00000920(daf-28)
Availability: available
Source References: PMID:34718610
Synonyms: mgIs40.
Alternate IDs: WB-STRAIN:GR1455, CGC_GR1455
Notes: mgIs40 [daf-28p::GFP].
Proper citation: RRID:WB-STRAIN:WBStrain00007937 Copy
http://www.wormbase.org/db/get?name=WBStrain00007936
Source Database: WormBase (WB)
Affected Genes: WBGene00002285(let-7)|WBGene00006743(unc-3)
Genomic Alteration: WBGene00002285(let-7), WBGene00006743(unc-3)
Availability: available
Source References: EMPTY
Synonyms: veIs13 V; let-7(mn112) unc-3(e151) X; mgEx725.
Alternate IDs: WB-STRAIN:GR1452, CGC_GR1452
Notes: veIs13 [col-19::GFP + rol-6(su1006)] V. mgEx725 [lin-4::let-7 + ttx-3::RFP]. Pick RFP+ to maintain. mgEx725 rescues lethality of let-7(mn112). Precocious expression of col-19::GFP at the L4 stage. Reference: Hayes GD, Riedel CG, Ruvkun G. 2011. Genes Dev. 2011 Oct 1;25(19):2079-92.
Proper citation: RRID:WB-STRAIN:WBStrain00007936 Copy
http://www.wormbase.org/db/get?name=WBStrain00007948
Source Database: WormBase (WB)
Affected Genes: WBGene00021634(rde-10)
Genomic Alteration: WBGene00021634(rde-10)
Availability: available
Source References: EMPTY
Synonyms: rde-10(mg458) I.
Alternate IDs: WB-STRAIN:GR1808, CGC_GR1808
Notes: RNAi-defective. Reference: Zhang C, et al. Curr Biol. 2012 May 22;22(10):881-90.
Proper citation: RRID:WB-STRAIN:WBStrain00007948 Copy
http://www.wormbase.org/db/get?name=WBStrain00007944
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(ed3) III; mgSi3 IV.
Alternate IDs: WB-STRAIN:GR1719, CGC_GR1719
Notes: Made_by: Tai Montgomery|"mgSi3 [(pCMP2)ubl-1p::GFP::ubl-1-3'UTR + Cbr-unc-119(+)] IV. Strong ubiquitous GFP expression. Can be used as a control for a strain containing an endogenous siRNA sensor (GR1720). Reference: Montgomery TA, et al. PLoS Genet. 2012;8(4):e1002616."
Proper citation: RRID:WB-STRAIN:WBStrain00007944 Copy
http://www.wormbase.org/db/get?name=WBStrain00007943
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: mgEx481.
Alternate IDs: WB-STRAIN:GR1674, CGC_GR1674
Notes: Made_by: Susan Paradis|"mgEx481 [pdk-1::GFP::unc-54 3'UTR + rol-6(su1006)]. Pick Rollers to maintain. PDK-1::GFP translational fusion containing 9 kb akt-1 genomic DNA including 2.9 kb of 5' upstream regulatory region and 6.1 kb of coding region (including exons and introns) fused in-frame to GFP with unc-54 3' UTR. Reference: Paradis S, et al. Genes Dev. 1999 Jun 1;13(11):1438-52."
Proper citation: RRID:WB-STRAIN:WBStrain00007943 Copy
http://www.wormbase.org/db/get?name=WBStrain00007942
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: mgEx341.
Alternate IDs: WB-STRAIN:GR1673, CGC_GR1673
Notes: Made_by: Susan Paradis|"mgEx341 [akt-2::GFP::unc-54 3'UTR + rol-6(su1006)]. Pick Rollers to maintain. AKT-2::GFP translational fusion containing 5.2 kb akt-1 genomic DNA including 2.1 kb of 5' upstream regulatory region and 3.1 kb of coding region (including exons and introns) fused in-frame to GFP with unc-54 3' UTR. Reference: Paradis S, Ruvkun G. Genes Dev. 1998 Aug 15;12(16):2488-98."
Proper citation: RRID:WB-STRAIN:WBStrain00007942 Copy
http://www.wormbase.org/db/get?name=WBStrain00007941
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: mgEx340.
Alternate IDs: WB-STRAIN:GR1672, CGC_GR1672
Notes: Made_by: Susan Paradis|"mgEx340 [akt-1::GFP::unc-54 3'UTR + rol-6(su1006)]. Pick Rollers to maintain. AKT-1::GFP translational fusion containing 6.7 kb akt-1 genomic DNA including 3.2 kb of 5' upstream regulatory region and 3.5 kb of coding region (including exons and introns) fused in-frame to GFP with unc-54 3' UTR. Reference: Paradis S, Ruvkun G. Genes Dev. 1998 Aug 15;12(16):2488-98."
Proper citation: RRID:WB-STRAIN:WBStrain00007941 Copy
http://www.wormbase.org/db/get?name=WBStrain00007960
Source Database: WormBase (WB)
Affected Genes: WBGene00000905(daf-9)|WBGene00001069(dpy-7)
Genomic Alteration: WBGene00000905(daf-9), WBGene00001069(dpy-7)
Availability: available
Source References: EMPTY
Synonyms: daf-9(e1406) dpy-7(sc27) X; mgEx663.
Alternate IDs: WB-STRAIN:GR2118, CGC_GR2118
Notes: mgEx663 [dpy-7p::daf-9B(cDNA)::GFP + mec-7::GFP]. Pick GFP+ to maintain. GFP fusion containing 0.4 kb dpy-7 promoter and daf-9 isoform B cDNA. Reference: Mak HY, Ruvkun G. Development. 2004 Apr;131(8):1777-86.
Proper citation: RRID:WB-STRAIN:WBStrain00007960 Copy
http://www.wormbase.org/db/get?name=WBStrain00007959
Source Database: WormBase (WB)
Affected Genes: WBGene00000898(daf-2)
Genomic Alteration: WBGene00000898(daf-2)
Availability: available
Source References: EMPTY
Synonyms: daf-2(e1365) III; mgIs35.
Alternate IDs: WB-STRAIN:GR2117, CGC_GR2117
Notes: mgIs35 [ins-1(genomic) + mec-7p::GFP]. Temperature-sensitive. Maintain at 15C. Daf-c. High penetrance of dauer formation at 20C. Integration of mgEx557. Reference: Pierce SB, et al. Genes Dev. 2001 Mar 15;15(6):672-86.|"Mutagen:Gamma radiation"
Proper citation: RRID:WB-STRAIN:WBStrain00007959 Copy
http://www.wormbase.org/db/get?name=WBStrain00007958
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: mgEx579.
Alternate IDs: WB-STRAIN:GR2116, CGC_GR2116
Notes: mgEx579 [ins-18p::GFP + rol-6(su1006)]. Pick Rollers to maintain. ins-18::GFP promoter fusion containing 4.9 kb upstream regulatory sequence and 2.1 kb of coding region (including exons and introns) driving GFP expression with 0.8 kb downstream sequence. Reference: Pierce SB, et al. Genes Dev. 2001 Mar 15;15(6):672-86.
Proper citation: RRID:WB-STRAIN:WBStrain00007958 Copy
http://www.wormbase.org/db/get?name=WBStrain00007956
Source Database: WormBase (WB)
Affected Genes: WBGene00012394(hsd-1)
Genomic Alteration: WBGene00012394(hsd-1)
Availability: available
Source References: EMPTY
Synonyms: hsd-1(mg433) I.
Alternate IDs: WB-STRAIN:GR2063, CGC_GR2063
Notes: Weak Hid. Eak.
Proper citation: RRID:WB-STRAIN:WBStrain00007956 Copy
http://www.wormbase.org/db/get?name=WBStrain00008001
Source Database: WormBase (WB)
Affected Genes: WBGene00001073(dpy-11)|WBGene00001345(fos-1)|WBGene00006778(unc-42)
Genomic Alteration: WBGene00001073(dpy-11), WBGene00001345(fos-1), WBGene00006778(unc-42)
Availability: available
Source References: PMID:8500652
Synonyms: fos-1(ar105)/dpy-11(e224) unc-42(e270) V.
Alternate IDs: WB-STRAIN:GS384, CGC_GS384
Notes: Heterozygotes are WT and segregate WT, Steriles with an Everted Vul and DpyUncs. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. ar105 previously called evl-5(ar105).
Proper citation: RRID:WB-STRAIN:WBStrain00008001 Copy
http://www.wormbase.org/db/get?name=WBStrain00007972
Source Database: WormBase (WB)
Affected Genes: WBGene00022856(cth-2)
Genomic Alteration: WBGene00022856(cth-2)
Availability: available
Source References: EMPTY
Synonyms: cth-2(mg599) II.
Alternate IDs: WB-STRAIN:GR2257, CGC_GR2257
Notes: Can be maintained on OP50. Suppresses Moco-deficient larval lethality. Reference: Warnhoff K & Ruvkun G. Nat Chem Biol. 2019 Mar 25. doi: 10.1038/s41589-019-0249-y.
Proper citation: RRID:WB-STRAIN:WBStrain00007972 Copy
http://www.wormbase.org/db/get?name=WBStrain00007971
Source Database: WormBase (WB)
Affected Genes: WBGene00009885(moc-5)
Genomic Alteration: WBGene00009885(moc-5)
Availability: available
Source References: EMPTY
Synonyms: F49E2.1(mg589) X.
Alternate IDs: WB-STRAIN:GR2256, CGC_GR2256
Notes: F49E2.1. Can be maintained on OP50. Requires dietary Moco for viability. Reference: (F49E2.1 referred to as moc-5) Warnhoff K & Ruvkun G. Nat Chem Biol. 2019 Mar 25. doi: 10.1038/s41589-019-0249-y.
Proper citation: RRID:WB-STRAIN:WBStrain00007971 Copy
http://www.wormbase.org/db/get?name=WBStrain00007965
Source Database: WormBase (WB)
Affected Genes: WBGene00004766(sel-9)
Genomic Alteration: WBGene00004766(sel-9)
Availability: available
Source References: EMPTY
Synonyms: sel-9(mg550) V.
Alternate IDs: WB-STRAIN:GR2232, CGC_GR2232
Notes: Made_by: Nicholas Lehrbach|"Superficially wild-type."
Proper citation: RRID:WB-STRAIN:WBStrain00007965 Copy
http://www.wormbase.org/db/get?name=WBStrain00007982
Source Database: WormBase (WB)
Affected Genes: WBGene00001073(dpy-11)|WBGene00003001(lin-12)|WBGene00004766(sel-9)|WBGene00006768(unc-32)
Genomic Alteration: WBGene00001073(dpy-11), WBGene00003001(lin-12), WBGene00004766(sel-9), WBGene00006768(unc-32)
Availability: available
Source References: PMID:8293978
Synonyms: unc-32(e189) lin-12(n676n930) III; dpy-11(e224) sel-9(ar22) V.
Alternate IDs: WB-STRAIN:GS107, CGC_GS107
Notes: DpyUnc. At 25C ar22 recessively suppresses the Egl defect of n676n930. At 15C ar22 dominantly suppresses the 2 AC-Egl phenotype of n676n930. Suppresses the vulval lineage defects and proximal mitosis defects of lin-12. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
Proper citation: RRID:WB-STRAIN:WBStrain00007982 Copy
http://www.wormbase.org/db/get?name=WBStrain00007981
Source Database: WormBase (WB)
Affected Genes: WBGene00003001(lin-12)|WBGene00006768(unc-32)
Genomic Alteration: WBGene00003001(lin-12), WBGene00006768(unc-32)
Availability: available
Source References: PMID:8293977
Synonyms: unc-32(e189) lin-12(n676n930) III.
Alternate IDs: WB-STRAIN:GS60, CGC_GS60
Notes: Unc. Temperature sensitive hypomorphic lin-12 allele. At restrictive temperature of 25C: 100% Egl in unc-32 background (95% Egl without unc-32); 30% have 2 anchor cells, some proximal mitosis, abnormal vulval lineages but has opening; leaks some eggs; mates with males. At permissive temperature of 15C: 93% Egl(+) and 7% Egl(-) [lin-12(d)-like: no anchor cell and no vulval opening]. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.
Proper citation: RRID:WB-STRAIN:WBStrain00007981 Copy
http://www.wormbase.org/db/get?name=WBStrain00007980
Source Database: WormBase (WB)
Affected Genes: WBGene00003514(myo-2)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00003514(myo-2), WBGene00006843(unc-119)
Availability: available
Source References: PMID:32088829, PMID:37080524, PMID:37838776, PMID:39149885, PMID:39329779
Synonyms: gnaIs2 [myo-2p::YFP + unc-119p::Abeta1-42]
Alternate IDs: WB-STRAIN:GRU102, CGC_GRU102
Notes: gnaIs2 [myo-2p::YFP + unc-119p::Abeta1-42]. Pan-neuronal amyloid beta1-42 expression. Impaired neuromuscular and sensorimotor behavior. See GRU101 for wild-type control strain. Reference: Fong S, et al. Sci Rep. 2016 Sep 22;6:33781. doi: 10.1038/srep33781.|"Supplementary_genotype gnaIs2 [myo-2p::YFP + unc-119p::Abeta1-42],"|[2020-10-08T19:09:27.569Z WBPerson324] Ressurect Strain: Genotype: gnaIs2 [myo-2p::YFP + unc-119p::humanAbeta1-42]|[2020-10-08T23:35:51.358Z WBPerson324] Ressurect Strain: Genotype: gnaIs2 [myo-2p::YFP + unc-119p::Abeta1-42]
Proper citation: RRID:WB-STRAIN:WBStrain00007980 Copy
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