Searching the RRID Resource Information Network
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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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B6N.129X1-Ntrk2tm1Lfr/Mmucd Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000187-UCD | Mus musculus | Research areas: Cell Biology, Developmental Biology, Diabetes, Neurobiology, Research Tools; Mutation Type: Targeted Mutation ; Collection: | abnormal visual cortex morphology [MP:0000805]| abnormal somatosensory cortex morphology [MP:0000859]| abnormal neuron morphology [MP:0002882]| decreased retinal ganglion cell number [MP:0006309]| abnormal retinal ganglion cell morphology [MP:0008056]| abnormal dendrite morphology [MP:0008143]| decreased neuron number [MP:0008948] | Ntrk2 | 000187-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:10798407 PMID:10995833 PMID:11836532 |
MMRRC_187-UCD, MMRRC_000187, MMRRC_187 | 2026-08-01 05:32:03 | 1 | |||
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B6.129-Kif3atm2Gsn/Mmucd Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000135-UCD | Mus musculus | Research areas: Apoptosis, Cell Biology, Models for Human Disease, Neurobiology, Sensorineural; Mutation Type: Targeted Mutation ; Collection: | short mandible [MP:0000088]| abnormal nasal bone morphology [MP:0000102]| abnormal basisphenoid bone morphology [MP:0000106]| abnormal frontal bone morphology [MP:0000107]| abnormal long bone epiphysis morphology [MP:0000131]| abnormal rib morphology [MP:0000150]| abnormal long bone hypertrophic chondrocyte zone [MP:0000165]| abnormal chondrocyte morphology [MP:0000166]| abnormal cranium morphology [MP:0000438]| abnormal maxilla morphology [MP:0000455]| kidney cortex cysts [MP:0000522]| short limbs [MP:0000547]| polydactyly [MP:0000562]| decreased body size [MP:0001265]| ocular hypertelorism [MP:0001300]| postnatal growth retardation [MP:0001732]| abnormal craniofacial bone morphology [MP:0002116]| abnormal brain morphology [MP:0002152]| absent corpus callosum [MP:0002196]| abnormal nasal septum morphology [MP:0002239]| disproportionate dwarf [MP:0002427]| abnormal premaxilla morphology [MP:0002820]| abnormal long bone epiphyseal plate morphology [MP:0003055]| enlarged kidney [MP:0003068]| renal interstitial fibrosis [MP:0003215]| kidney failure [MP:0003606]| abnormal long bone epiphyseal plate proliferative zone [MP:0003662]| kidney cysts [MP:0003675]| abnormal craniofacial development [MP:0003935]| thoracic vertebral fusion [MP:0004623]| decreased length of long bones [MP:0004686]| absent mandibular condyloid process [MP:0004911]| lethargy [MP:0005202]| abnormal palatine bone morphology [MP:0005249]| spina bifida occulta [MP:0005297]| increased blood urea nitrogen level [MP:0005565]| abnormal limb bud morphology [MP:0005650]| decreased long bone epiphyseal plate size [MP:0006396]| disorganized long bone epiphyseal plate [MP:0006397]| abnormal endochondral bone ossification [MP:0008272]| polycystic kidney [MP:0008528]| cleft secondary palate [MP:0009890]| abnormal basicranium morphology [MP:0010029]| kidney medulla cysts [MP:0011307]| renal tubule atrophy [MP:0011346]| increased kidney apoptosis [MP:0011368]| abnormal cranial neural crest cell morphology [MP:0012754]| increased cranial neural crest cell proliferation [MP:0012759]| abnormal cell cytoskeleton morphology [MP:0020378]| absent kidney epithelial cell primary cilium [MP:0020384]| broad frontonasal prominence [MP:0030251]| absent mandibular ramus [MP:0030269]| anterior cranium occultum [MP:0030276] | Kif3a | 000135-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:10943838 | MMRRC_135-UCD, MMRRC_000135, MMRRC_135 | 2026-08-01 05:32:02 | 1 | |||
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B6;129X1-Itga8tm1Lfr/Mmucd Resource Report Resource Website |
RRID:MMRRC_000193-UCD | Mus musculus | Research areas: Cell Biology, Developmental Biology, Models for Human Disease, Neurobiology, Sensorineural; Mutation Type: Targeted Mutation ; Collection: | absent kidney [MP:0000520]| abnormal kidney development [MP:0000527]| abnormal ureter morphology [MP:0000534]| abnormal spatial learning [MP:0001463]| reduced long term potentiation [MP:0001473]| abnormal motor coordination/balance [MP:0001516]| abnormal kidney morphology [MP:0002135]| small kidney [MP:0002989]| abnormal cell migration [MP:0003091]| abnormal pulmonary elastic fiber morphology [MP:0003209]| abnormal cell adhesion [MP:0003566]| single kidney [MP:0003604]| abnormal ureter development [MP:0003672]| absent ureter [MP:0003722]| abnormal vestibular hair cell stereociliary bundle morphology [MP:0004515]| fused vestibular hair cell stereocilia [MP:0004516]| decreased vestibular hair cell stereocilia number [MP:0004517]| impaired branching involved in ureteric bud morphogenesis [MP:0004936]| adhesive atelectasis [MP:0010818]| abnormal lung saccule morphology [MP:0010825]| dilated respiratory conducting tubes [MP:0010856]| fused right lung lobes [MP:0010977]| abnormal ureteric bud invasion [MP:0010983]| impaired lung lobe morphogenesis [MP:0011011]| abnormal branching involved in lung morphogenesis [MP:0011024]| postnatal lethality [MP:0011086] | Itga8 | 000193-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:9054500 | MMRRC_193-UCD, MMRRC_000193, MMRRC_193 | 2026-08-01 05:32:11 | 0 | |||
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B6.129S4-Fn1tm1Bwg/Mmnc Resource Report Resource Website |
RRID:MMRRC_000226-UNC | Mus musculus | Research areas: Cardiovascular, Cell Biology, Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | increased carcinoma incidence [MP:0002038]| no abnormal phenotype detected [MP:0002169]| decreased circulating VLDL cholesterol level [MP:0005146]| abnormal cholesterol homeostasis [MP:0005278]| decreased susceptibility to atherosclerosis [MP:0005341] | Fn1 | 000226-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:14976060 | MMRRC_226-UNC, MMRRC_000226, MMRRC_226 | 2026-08-01 05:32:11 | 0 | |||
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B6.129-Kif5atm2Gsn/Mmucd Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000224-UCD | Mus musculus | Research areas: Apoptosis, Cell Biology, Developmental Biology, Internal/Organ, Models for Human Disease, Neurobiology, Research Tools, Sensorineural; Mutation Type: Targeted Mutation ; Collection: | tremors [MP:0000745]| hindlimb paralysis [MP:0000755]| sporadic seizures [MP:0000951]| decreased body weight [MP:0001262]| decreased body size [MP:0001265]| impaired coordination [MP:0001405]| abnormal posture [MP:0001504]| premature death [MP:0002083]| abnormal axonal transport [MP:0004768]| axon degeneration [MP:0005405]| abnormal protein level [MP:0008469]| lethality at weaning [MP:0011084] | Kif5a | 000224-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12682084 | MMRRC_224-UCD, MMRRC_000224, MMRRC_224 | 2026-08-01 05:32:04 | 1 | |||
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B6.129X1-Xrcc1tm1Rpe/Mmmh Resource Report Resource Website |
RRID:MMRRC_000219-MU | Mus musculus | Research areas: Apoptosis, Cancer, Developmental Biology, Reproduction; Mutation Type: Targeted Mutation ; Collection: | absent mesoderm [MP:0001683]| abnormal endoderm development [MP:0001685]| failure to gastrulate [MP:0001696]| decreased embryo size [MP:0001698]| embryonic growth arrest [MP:0001730]| embryonic lethality [MP:0011092]| complete penetrance [MP:0011097] | Xrcc1 | 000219-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:10191063 | MMRRC_219-MU, MMRRC_000219, MMRRC_219 | 2026-08-01 05:32:11 | 0 | |||
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B6;129P2-Gabra6tm2(cre)Wwis/Mmucd Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000213-UCD | Mus musculus | Research areas: Neurobiology; Mutation Type: Targeted Mutation ; Collection: | abnormal learning/memory/conditioning [MP:0002063]| no abnormal phenotype detected [MP:0002169]| abnormal motor learning [MP:0002804]| abnormal neuron morphology [MP:0002882]| abnormal GABA-mediated receptor currents [MP:0004008]| abnormal cerebellar granule cell morphology [MP:0004098]| abnormal action potential [MP:0005402]| abnormal optokinetic reflex [MP:0009619]| abnormal vestibuloocular dark reflex [MP:0011039]| abnormal vestibuloocular light reflex [MP:0011040] | creGabra6 | 000213-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12820171 | MMRRC_213-UCD, MMRRC_000213, MMRRC_213 | 2026-08-01 05:32:03 | 3 | |||
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B6.Cg-Nfatc2tm1Rao/Mmnc Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000197-UNC | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | abnormal T cell differentiation [MP:0002145]| abnormal double-negative T cell morphology [MP:0002407]| abnormal mast cell physiology [MP:0002423]| abnormal B cell physiology [MP:0002459]| increased T cell apoptosis [MP:0006413]| decreased tumor necrosis factor secretion [MP:0008561]| decreased interleukin-13 secretion [MP:0008673]| decreased interleukin-2 secretion [MP:0008688]| decreased interleukin-4 secretion [MP:0008700] | Nfatc2 | 000197-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:9516119 PMID:9430230 |
MMRRC_197-UNC, MMRRC_000197, MMRRC_197 | 2026-08-01 05:32:03 | 2 | |||
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B6.129S1-Kcnj10tm1Lst/Mmnc Resource Report Resource Website |
RRID:MMRRC_000209-UNC | Mus musculus | Research areas: Apoptosis, Developmental Biology, Models for Human Disease, Neurobiology, Research Tools, Sensorineural; Mutation Type: Targeted Mutation ; Collection: | abnormal cochlea morphology [MP:0000031]| organ of Corti degeneration [MP:0000043]| abnormal stria vascularis morphology [MP:0000048]| tremors [MP:0000745]| weakness [MP:0000746]| hindlimb paralysis [MP:0000755]| abnormal myelination [MP:0000920]| abnormal oligodendrocyte morphology [MP:0000953]| abnormal spinal cord morphology [MP:0000955]| decreased body weight [MP:0001262]| decreased body size [MP:0001265]| dehydration [MP:0001429]| abnormal posture [MP:0001504]| abnormal motor coordination/balance [MP:0001516]| impaired righting response [MP:0001523]| impaired balance [MP:0001525]| postnatal growth retardation [MP:0001732]| polyuria [MP:0001762]| abnormal motor capabilities/coordination/movement [MP:0002066]| abnormal nervous system electrophysiology [MP:0002272]| abnormal renal tubule morphology [MP:0002703]| cochlear ganglion degeneration [MP:0002857]| decreased urine calcium level [MP:0002986]| abnormal tectorial membrane morphology [MP:0003149]| abnormal scala media morphology [MP:0003169]| vestibular ganglion degeneration [MP:0004298]| vestibular hair cell degeneration [MP:0004324]| vestibular saccular macula degeneration [MP:0004331]| utricular macular degeneration [MP:0004334]| cochlear inner hair cell degeneration [MP:0004398]| cochlear outer hair cell degeneration [MP:0004404]| abnormal crista ampullaris neuroepithelium morphology [MP:0004409]| absent endocochlear potential [MP:0004410]| abnormal cochlear nerve morphology [MP:0004716]| abnormal eye physiology [MP:0005253]| axon degeneration [MP:0005405]| jerky movement [MP:0005424]| abnormal eye electrophysiology [MP:0005551]| abnormal Reissner membrane morphology [MP:0006021]| collapsed Reissner membrane [MP:0006024]| distended Reissner membrane [MP:0006025]| increased urine sodium level [MP:0006316]| impaired hearing [MP:0006325]| absent pinna reflex [MP:0006358]| absent startle reflex [MP:0006359]| abnormal cochlear endolymph ionic homeostasis [MP:0006403]| abnormal spinal cord white matter morphology [MP:0008027]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011471]| decreased urine creatinine level [MP:0011967] | Kcnj10 | 000209-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:10908613 | MMRRC_209-UNC, MMRRC_000209, MMRRC_29 | 2026-08-01 05:32:11 | 0 | |||
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C.129S2(B6)-Ighmtm1Cgn/Mmmh Resource Report Resource Website Issue Issue |
RRID:MMRRC_000205-MU | Mus musculus | Research areas: Cardiovascular, Immunology and Inflammation, Research Tools, Virology; Mutation Type: Targeted Mutation ; Collection: | decreased bone mineral density [MP:0000063]| abnormal trabecular bone morphology [MP:0000130]| decreased compact bone thickness [MP:0000135]| enlarged heart [MP:0000274]| increased cell proliferation [MP:0000351]| abnormal intestinal epithelium morphology [MP:0000488]| abnormal spleen morphology [MP:0000689]| enlarged lymph nodes [MP:0000702]| abnormal skin condition [MP:0001191]| abnormal cardiovascular system physiology [MP:0001544]| abnormal humoral immune response [MP:0001800]| arrested B cell differentiation [MP:0001802]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| thymus hypoplasia [MP:0001823]| abnormal antigen presentation [MP:0001835]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| heart inflammation [MP:0001853]| myocarditis [MP:0001856]| kidney inflammation [MP:0001859]| abnormal lymphatic vessel morphology [MP:0001879]| premature death [MP:0002083]| abnormal respiratory system physiology [MP:0002133]| abnormal B cell differentiation [MP:0002144]| abnormal spleen marginal sinus morphology [MP:0002363]| abnormal B lymphocyte antigen presentation [MP:0002453]| decreased immunoglobulin level [MP:0002460]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| tubular nephritis [MP:0002704]| increased urine protein level [MP:0002962]| abnormal cytokine secretion [MP:0003009]| cardiac fibrosis [MP:0003141]| thrombocytopenia [MP:0003179]| small intestinal inflammation [MP:0003306]| increased susceptibility to induced arthritis [MP:0003724]| increased autoantibody level [MP:0003725]| abnormal compact bone morphology [MP:0003797]| abnormal PR interval [MP:0003901]| insulitis [MP:0004031]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| increased susceptibility to autoimmune diabetes [MP:0004803]| decreased susceptibility to autoimmune diabetes [MP:0004804]| decreased spleen weight [MP:0004953]| increased osteoclast cell number [MP:0004984]| increased T cell number [MP:0005015]| decreased B cell number [MP:0005017]| abnormal response to infection [MP:0005025]| increased susceptibility to parasitic infection [MP:0005027]| abnormal T cell proliferation [MP:0005094]| decreased T cell proliferation [MP:0005095]| cachexia [MP:0005150]| decreased susceptibility to injury [MP:0005166]| abnormal pancreatic islet morphology [MP:0005215]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005559]| increased circulating glucose level [MP:0005616]| decreased susceptibility to type IV hypersensitivity reaction [MP:0006387]| abnormal T cell number [MP:0008071]| absent B cells [MP:0008075]| decreased CD4-positive [MP:0008079]| alpha beta T cell number [MP:0008127]| decreased CD8-positive [MP:0008171]| alpha-beta T cell number [MP:0008201]| decreased dendritic cell number [MP:0008211]| abnormal mature B cell morphology [MP:0008212]| absent follicular dendritic cells [MP:0008213]| decreased mature B cell number [MP:0008240]| absent mature B cells [MP:0008241]| absent immature B cells [MP:0008401]| abnormal spleen marginal zone macrophage morphology [MP:0008470]| abnormal metallophilic macrophage morphology [MP:0008495]| abnormal CD8 positive [MP:0009346]| alpha-beta intraepithelial T cell morphology [MP:0010965]| abnormal spleen B cell follicle morphology [MP:0012431] | Ighm | 000205-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:10553048 | MMRRC_205-MU, MMRRC_000205, MMRRC_25 | 2026-08-01 05:32:03 | 0 | |||
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B6.Cg-Sod2tm1Cje/Mmmh Resource Report Resource Website |
RRID:MMRRC_000202-MU | Mus musculus | Research areas: Apoptosis, Cardiovascular, Cell Biology, Diabetes, Hematology, Metabolism, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection: | decreased hematocrit [MP:0000208]| enlarged heart [MP:0000274]| thin ventricular wall [MP:0000280]| abnormal liver physiology [MP:0000609]| tremors [MP:0000745]| abnormal skeletal muscle morphology [MP:0000759]| abnormal forebrain morphology [MP:0000783]| abnormal cerebral cortex morphology [MP:0000788]| abnormal frontal lobe morphology [MP:0000798]| abnormal hippocampus morphology [MP:0000807]| abnormal thalamus morphology [MP:0000832]| abnormal cerebellum morphology [MP:0000849]| abnormal trigeminal V mesencephalic nucleus morphology [MP:0000906]| abnormal trigeminal motor nucleus morphology [MP:0000911]| abnormal motor neuron morphology [MP:0000937]| decreased spinal cord size [MP:0000956]| decreased body weight [MP:0001262]| abnormal retina morphology [MP:0001325]| abnormal optic nerve morphology [MP:0001330]| ataxia [MP:0001393]| impaired coordination [MP:0001405]| abnormal gait [MP:0001406]| impaired righting response [MP:0001523]| cardiac hypertrophy [MP:0001625]| postnatal growth retardation [MP:0001732]| increased tumor incidence [MP:0002020]| seizures [MP:0002064]| premature death [MP:0002083]| abnormal brain morphology [MP:0002152]| hyperoxia [MP:0002319]| abnormal blood gas level [MP:0002329]| increased circulating ketone body level [MP:0002575]| hepatic steatosis [MP:0002628]| spongiform encephalopathy [MP:0002654]| dilated heart left ventricle [MP:0002753]| dilated heart right ventricle [MP:0002754]| dilated cardiomyopathy [MP:0002795]| increased heart weight [MP:0002833]| fatigue [MP:0002899]| increased circulating alkaline phosphatase level [MP:0002968]| increased liver weight [MP:0002981]| abnormal blood pH regulation [MP:0003027]| acidosis [MP:0003031]| hypocapnia [MP:0003032]| abnormal skeletal muscle fiber morphology [MP:0003084]| cardiac fibrosis [MP:0003141]| calcinosis [MP:0003195]| neuron degeneration [MP:0003224]| oxidative stress [MP:0003674]| pallor [MP:0003717]| abnormal retinal photoreceptor layer morphology [MP:0003728]| increased hepatocyte apoptosis [MP:0003887]| hypotonia [MP:0004144]| decreased fetal size [MP:0004200]| decreased spinal cord ventral horn cell number [MP:0005113]| abnormal retinal pigment epithelium morphology [MP:0005201]| abnormal brainstem morphology [MP:0005277]| abnormal enzyme/coenzyme level [MP:0005319]| increased circulating aspartate transaminase level [MP:0005343]| axon degeneration [MP:0005405]| decreased circulating glucose level [MP:0005560]| increased blood urea nitrogen level [MP:0005565]| abnormal cell physiology [MP:0005621]| abnormal mitochondrial physiology [MP:0006036]| brain vacuoles [MP:0008025]| thin retinal inner nuclear layer [MP:0008511]| decreased neuron number [MP:0008948]| decreased skeletal muscle fiber size [MP:0009400]| abnormal blood homeostasis [MP:0009642]| abnormal urine homeostasis [MP:0009643]| aciduria [MP:0010028]| abnormal respiratory electron transport chain [MP:0010955]| abnormal aerobic respiration [MP:0010957]| abnormal tricarboxylic acid cycle [MP:0010958]| decreased body surface temperature [MP:0011015]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011089]| perinatal lethality [MP:0011109]| complete penetrance [MP:0012431]| lethality throughout fetal growth and development [MP:0012551]| incomplete penetrance [MP:0013404]| increased lymphoma incidence [MP:0020543] | Sod2 | 000202-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:7493016 PMID:11677043 PMID:9774481 |
MMRRC_202-MU, MMRRC_000202, MMRRC_22 | 2026-08-01 05:32:03 | 0 | |||
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B6.129S-Cd74tm2Liz/Mmnc Resource Report Resource Website |
RRID:MMRRC_000429-UNC | Mus musculus | Research areas: ; Mutation Type: Targeted Mutation ; Collection: | increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| abnormal antigen presentation via MHC class II [MP:0005041]| increased T cell proliferation [MP:0005348]| decreased interleukin-2 secretion [MP:0008688] | Cd74 | 000429-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:7553002 PMID:8977190 PMID:11483509 |
MMRRC_429-UNC, MMRRC_000429, MMRRC_429 | 2026-08-01 05:32:06 | 0 | |||
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B6;129S-St3gal5tm1Rlp/Mmmh Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000374-MU | Mus musculus | Research areas: Apoptosis, Cancer, Cell Biology, Dermatology, Diabetes, Immunology and Inflammation, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection: | hypoglycemia [MP:0000189]| abnormal glucose homeostasis [MP:0002078]| abnormal lipid homeostasis [MP:0002118]| increased insulin sensitivity [MP:0002891]| improved glucose tolerance [MP:0005292] | St3gal5 | 000374-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12629211 | MMRRC_374-MU, MMRRC_000374, MMRRC_374 | 2026-08-01 05:32:06 | 1 | |||
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STOCK Pdx1tm1Cvw/Mmnc Resource Report Resource Website |
RRID:MMRRC_000439-UNC | Mus musculus | Research areas: Developmental Biology, Diabetes, Endocrine Deficiency, Research Tools; Mutation Type: Targeted Mutation ; Collection: BCBC-Beta Cell Biology Consortium | sparse hair [MP:0000416]| abnormal stomach morphology [MP:0000470]| abnormal foregut morphology [MP:0000474]| abnormal small intestine morphology [MP:0000496]| abnormal liver development [MP:0000596]| thin skin [MP:0001199]| decreased body weight [MP:0001262]| weight loss [MP:0001263]| dehydration [MP:0001429]| hyperglycemia [MP:0001559]| postnatal growth retardation [MP:0001732]| increased urine glucose level [MP:0001759]| abnormal pancreas morphology [MP:0001944]| decreased circulating insulin level [MP:0002727]| increased insulin sensitivity [MP:0002891]| abnormal bile duct development [MP:0002929]| decreased insulin secretion [MP:0003059]| abnormal duodenum morphology [MP:0003271]| decreased pancreatic beta cell number [MP:0003339]| abnormal pancreatic beta cell physiology [MP:0003562]| absent pancreas [MP:0003655]| small pancreas [MP:0004247]| abnormal pancreatic islet morphology [MP:0005215]| abnormal pancreatic beta cell morphology [MP:0005217]| improved glucose tolerance [MP:0005292]| impaired glucose tolerance [MP:0005293]| increased circulating glucose level [MP:0005559]| decreased pancreas weight [MP:0009109]| abnormal pancreatic duct morphology [MP:0009143]| abnormal pancreatic acinar cell morphology [MP:0009146]| abnormal pancreatic islet size [MP:0009170]| small pancreatic islets [MP:0009172]| abnormal pancreatic beta cell differentiation [MP:0009175]| increased pancreatic alpha cell number [MP:0009176]| increased pancreatic delta cell number [MP:0009180]| disorganized pancreatic islets [MP:0009254]| abnormal pyloric sphincter morphology [MP:0009861]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011820]| decreased pancreatic beta cell proliferation [MP:0012520]| absent Brunner's glands [MP:0014109]| increased pancreatic alpha cell proliferation [MP:0014117] | Pdx1 | 000439-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:8631275 | MMRRC_439-UNC, MMRRC_000439, MMRRC_439 | 2026-08-01 05:32:07 | 0 | |||
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B6.129S-Neurog3tm1(EGFP)Khk/Mmucd Resource Report Resource Website 1+ mentions Rating or validation data |
RRID:MMRRC_000344-UCD | Mus musculus | Research areas: Diabetes, Endocrine Deficiency; Mutation Type: Targeted Mutation ; Collection: BCBC-Beta Cell Biology Consortium | small stomach [MP:0002691]| disorganized stomach mucosa [MP:0005210]| increased stomach mucosa thickness [MP:0005211]| regional gastric metaplasia [MP:0005214]| abnormal pancreatic alpha cell morphology [MP:0005216]| abnormal pancreatic beta cell morphology [MP:0005217]| abnormal pancreatic delta cell morphology [MP:0005218] | Neurog3 | 000344-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12080087 | MMRRC_344-UCD, MMRRC_000344, MMRRC_344 | 2026-08-01 05:32:05 | 2 | |||
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B6.129S7-Chrna7tm2Bay/Mmnc Resource Report Resource Website |
RRID:MMRRC_000420-UNC | Mus musculus | Research areas: Cardiovascular, Neurobiology, Research Tools; Mutation Type: Targeted Mutation ; Collection: | tremors [MP:0000745]| abnormal somatosensory cortex morphology [MP:0000859]| hypoactivity [MP:0001402]| abnormal suckling behavior [MP:0001436]| abnormal brain morphology [MP:0002152]| increased neuron apoptosis [MP:0003203]| abnormal nicotine-mediated receptor currents [MP:0009475]| neonatal lethality [MP:0011087] | Chrna7 | 000420-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:10800961 PMID:11409732 PMID:11854451 |
MMRRC_420-UNC, MMRRC_000420, MMRRC_42 | 2026-08-01 05:32:13 | 0 | |||
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B6;129S7-Del(17Hspa1b-Hsp1a)1Dix/Mmucd Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000371-UCD | Mus musculus | Research areas: Apoptosis, Cancer, Cardiovascular, Cell Biology, Developmental Biology, Immunology and Inflammation, Models for Human Disease, Neurobiology, Reproduction; Mutation Type: Targeted Mutation ; Collection: | decreased cell proliferation [MP:0000352]| increased cellular sensitivity to gamma-irradiation [MP:0002007]| increased myocardial infarction size [MP:0003037]| neurofibrillary tangles [MP:0003214]| spontaneous chromosome breakage [MP:0004029]| induced chromosome breakage [MP:0004030]| abnormal cell cycle checkpoint function [MP:0004045]| tau protein deposits [MP:0004250]| decreased mitotic index [MP:0004759]| abnormal enzyme/coenzyme activity [MP:0005584]| abnormal cell physiology [MP:0005621]| abnormal spermatocyte morphology [MP:0006379]| early cellular replicative senescence [MP:0008008]| abnormal DNA repair [MP:0008058]| decreased birth weight [MP:0009674] | |Hspa1a|Hspa1b | 000371-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:14701760 PMID:12714332 PMID:14678980 |
MMRRC_371-UCD, MMRRC_000371, MMRRC_371 | 2026-08-01 05:32:06 | 1 | |||
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129S1.129P2(Cg)-Zfa-pstm1Ems/Mmnc Resource Report Resource Website |
RRID:MMRRC_000355-UNC | Mus musculus | Research areas: Cell Biology, Developmental Biology, Reproduction; Mutation Type: Targeted Mutation ; Collection: | Zfa-ps | 000355-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12906850 | MMRRC_355-UNC, MMRRC_000355, MMRRC_355 | 2026-08-01 05:32:13 | 0 | ||||
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B6.129-Tcrbtm1Mom Ifngtm1Ts/Mmnc Resource Report Resource Website Issue |
RRID:MMRRC_000337-UNC | Mus musculus | Research areas: Cancer, Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | enlarged liver [MP:0000599]| enlarged spleen [MP:0000691]| spleen hypoplasia [MP:0000694]| absent CD8-positive [MP:0000727]| alpha-beta T cells [MP:0000938]| motor neuron degeneration [MP:0001219]| thick epidermis [MP:0001243]| abnormal dermal layer morphology [MP:0001263]| weight loss [MP:0001805]| decreased IgG level [MP:0001807]| decreased IgA level [MP:0001823]| thymus hypoplasia [MP:0001825]| arrested T cell differentiation [MP:0002023]| increased B cell derived lymphoma incidence [MP:0002083]| premature death [MP:0002132]| abnormal respiratory system morphology [MP:0002133]| abnormal respiratory system physiology [MP:0002144]| abnormal B cell differentiation [MP:0002492]| decreased IgE level [MP:0002494]| increased IgM level [MP:0002495]| increased IgA level [MP:0002816]| colitis [MP:0003691]| abnormal microglial cell physiology [MP:0003725]| increased autoantibody level [MP:0003726]| decreased autoantibody level [MP:0003790]| absent CD4-positive [MP:0004762]| alpha beta T cells [MP:0004796]| increased anti-double stranded DNA antibody level [MP:0004829]| increased anti-histone antibody level [MP:0004939]| increased anti-chromatin antibody level [MP:0004947]| abnormal B cell morphology [MP:0005014]| skin inflammation [MP:0005015]| increased B cell number [MP:0005016]| increased T cell number [MP:0005017]| decreased lymphocyte cell number [MP:0005018]| decreased B cell number [MP:0005025]| decreased T cell number [MP:0005092]| abnormal response to infection [MP:0008075]| decreased double-positive T cell number [MP:0008079]| decreased CD4-positive [MP:0008098]| alpha beta T cell number [MP:0008173]| decreased CD8-positive [MP:0008181]| alpha-beta T cell number [MP:0008188]| decreased plasma cell number [MP:0008210]| increased follicular B cell number [MP:0008214]| increased marginal zone B cell number [MP:0008495]| abnormal transitional stage B cell morphology [MP:0009925]| increased mature B cell number [MP:0010229]| increased immature B cell number [MP:0010286]| decreased IgG1 level [MP:0011320]| increased transitional stage T2 B cell number [MP:0011427]| increased transitional stage T3 B cell number [MP:0020519]| increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466] | |Tcrb||Ifngr2 | 000337-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:1359428 PMID:11705890 |
MMRRC_337-UNC, MMRRC_000337, MMRRC_337 | 2026-08-01 05:32:13 | 0 | |||
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B6.Cg-Tcrdtm1Mom Tg(UBC-GFP)30Scha/Mmnc Resource Report Resource Website |
RRID:MMRRC_000340-UNC | Mus musculus | Research areas: Cancer, Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | enlarged liver [MP:0000599]| enlarged spleen [MP:0000691]| spleen hypoplasia [MP:0000694]| absent CD8-positive [MP:0000727]| alpha-beta T cells [MP:0001191]| abnormal skin condition [MP:0001194]| dermatitis [MP:0001805]| decreased IgG level [MP:0001807]| decreased IgA level [MP:0001823]| thymus hypoplasia [MP:0001825]| arrested T cell differentiation [MP:0002023]| increased B cell derived lymphoma incidence [MP:0002024]| increased T cell derived lymphoma incidence [MP:0002083]| premature death [MP:0002132]| abnormal respiratory system morphology [MP:0002133]| abnormal respiratory system physiology [MP:0002407]| abnormal double-negative T cell morphology [MP:0002492]| decreased IgE level [MP:0002494]| increased IgM level [MP:0002495]| increased IgA level [MP:0002796]| impaired skin barrier function [MP:0002816]| colitis [MP:0003306]| small intestinal inflammation [MP:0003725]| increased autoantibody level [MP:0003726]| decreased autoantibody level [MP:0003790]| absent CD4-positive [MP:0004762]| alpha beta T cells [MP:0004796]| increased anti-double stranded DNA antibody level [MP:0004829]| increased anti-histone antibody level [MP:0005014]| increased anti-chromatin antibody level [MP:0005015]| increased B cell number [MP:0005016]| increased T cell number [MP:0005018]| decreased lymphocyte cell number [MP:0005025]| decreased T cell number [MP:0005092]| abnormal response to infection [MP:0005617]| decreased double-positive T cell number [MP:0006042]| increased susceptibility to type IV hypersensitivity reaction [MP:0008098]| increased apoptosis [MP:0008173]| decreased plasma cell number [MP:0008181]| increased follicular B cell number [MP:0008188]| increased marginal zone B cell number [MP:0008210]| abnormal transitional stage B cell morphology [MP:0008214]| increased mature B cell number [MP:0008348]| increased immature B cell number [MP:0008356]| absent gamma-delta T cells [MP:0008495]| abnormal gamma-delta T cell differentiation [MP:0008757]| decreased IgG1 level [MP:0009925]| abnormal T cell receptor gamma chain V-J recombination [MP:0010229]| increased transitional stage T2 B cell number [MP:0010286]| increased transitional stage T3 B cell number [MP:0011320]| increased plasmacytoma incidence [MP:0011427]| abnormal glomerular capillary morphology [MP:0020519] | |Tcrd|Ubc|GFP| | 000340-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:8361537 | MMRRC_340-UNC, MMRRC_000340, MMRRC_34 | 2026-08-01 05:32:05 | 0 |
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