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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00047721
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119(ed3) III; czIs110.
Notes: czIs110 [mex-5p::GFP::KDEL::pie-1 3UTR + unc-119(+)]. GFP::KDEL is a marker of the luminal ER in the embryo. Reference: Lee et al., J Cell Biol. 2016 Sep 12;214(6):665-76.
Proper citation: RRID:WB-STRAIN:WBStrain00047721 Copy
http://www.wormbase.org/db/get?name=WBStrain00047890
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:31242447
Synonyms: unc-119(ed4) III; syIs360.
Alternate IDs: CGC_PS7127
Notes: Batch Strain object requested via get_NS_ids.pl|"Generated from papers flagged positive during the last month for data type afp_strain/other_strain."|"syIs360 [ets-10p::GFP + unc-119(+)]. Dauer decision marker that indicates commitment to dauer formation in neurons and intestine. Reference: Shih, PY, et al., Dev Biol. 2019 Jun 23. pii: S0012-1606(18)30788-7."
Proper citation: RRID:WB-STRAIN:WBStrain00047890 Copy
http://www.wormbase.org/db/get?name=WBStrain00048145
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: PMID:32650044
Synonyms: unc-119(ed3) III.
Notes: [2021-02-02T17:27:14.041Z WBPerson1983] New Strain: Genotype: unc-119(ed3) III Reference: WBPaper00059962
Proper citation: RRID:WB-STRAIN:WBStrain00048145 Copy
http://www.wormbase.org/db/get?name=WBStrain00048564
Source Database: WormBase (WB)
Affected Genes: WBGene00003161(mdf-2)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00003161(mdf-2), WBGene00006843(unc-119)
Availability: available
Source References: PMID:31588029
Synonyms: unc-119(ed3) III; mdf-2(lt4::loxP::Cbr-unc-119(+)::loxP) IV/nT1 [qIs51] (IV;V).
Alternate IDs: CGC_OD2174
Notes: CRISPR/Cas9 engineered deletion of mdf-2 in which the mdf-2 coding sequence was replaced by unc-119. Heterozygotes are wild-type GFP+ and segregate mdf-2 null homozygotes (low brood size/embryonic lethal), wild-type GFP+ heterozygotes, and arrested nT1[qIs51] aneuploids. Pick wild-type GFP+ and check for correct segregation of progeny to maintain. Unknown if unc-119(ed3) from parental strain is still carried in the background. gRNA sequence: Gccaaattccccagttttag Reference: Lara-Gonzalez P, et al. Dev Cell. 2019 Nov 4;51(3):313-325.e10. doi: 10.1016/j.devcel.2019.09.005. PMID: 31588029.|"Generated from papers flagged positive during the last month for data type afp_strain/other_strain."
Proper citation: RRID:WB-STRAIN:WBStrain00048564 Copy
http://www.wormbase.org/db/get?name=WBStrain00051957
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119(ed3) III; stxEx35.
Notes: stxEx35 [istr-1::TY1::eGFP::3xFLAG + Cbr-unc-119(+)]. Pick non-Unc to maintain. Constitutive expression of GFP. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of istr-1 coding sequence in fosmid WRM0636D_F01 by recombineering (TransgeneOme bacterial clone 5438954842362824 D10). Reference: Radetskaya O, et al. The PMK-3 (p38) Mitochondrial Retrograde Response Functions in Intestinal Cells to Extend Life via the ESCRT Machinery. bioRxiv 797308; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00051957 Copy
http://www.wormbase.org/db/get?name=WBStrain00049146
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: PMID:32293562
Synonyms: unc-119(ed3) III; hrtSi28 IV.
Notes: Generated from afp_otherstrain Paper data WBPaper000595481.|"hrtSi28 [des-2p::mKate2::maph-1.1 + unc-119(+)] IV. hrtSi28 inserted into cxTi10882. Expression of mKate2::MAPH-1.1 microtubule marker in PVD and FLP. Reference: He L, et al. eLife 2020;9:e55111 doi: 10.7554/eLife.55111."
Proper citation: RRID:WB-STRAIN:WBStrain00049146 Copy
http://www.wormbase.org/db/get?name=WBStrain00049949
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: PMID:33027250, PMID:37782660
Synonyms: ijmSi3 I; unc-119(ed3) III; ltIs37 IV.
Notes: Generated from papers flagged positive during the last month for data type afp_otherstrain and contains genotype and gene data.|"ijmSi3 [mex-5p::cls-2(re-encoded)::GFP::tbb-2 3'UTR + Cbr-unc-119(+)] I. ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. The coding sequence of GFP-tagged cls-2 in the transgene was re-coded using silent mutations to render it insensitive to RNAi-depletion of endogenous cls-2 expression. mCherry expression marks histones. Not known if unc-119(ed3) is still carried in the background of this strain. [NOTE: the ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV transgene was previously annotated as itIs37 in this strain. The correct name of the transgene is ltIs37 and not itIs37.] Reference: Schlientz A and Bowerman B. PLoS Genet. 2020 Oct 7;16(10):e1008751. doi: 10.1371/journal.pgen.1008751."|"Made_by: Aleesa Schlientz"|"Supplementary_genotype ijmSi3 [pJD342/pJD330; ChrI_5mex-5_cls-2reenc::GFP_3tbb-2; cb-unc-119(+)]I; unc-119(ed3) III?; itIs37[pie-1p::mCherry::H2B::pie-1 3'UTR + unc-119(+)] IV"
Proper citation: RRID:WB-STRAIN:WBStrain00049949 Copy
http://www.wormbase.org/db/get?name=WBStrain00050174
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: PMID:34003969
Synonyms: vsSi32 unc-119(ed3) III.
Notes: Generated from papers flagged positive during the last month for data type afp_otherstrain and contains genotype and gene data.|"vsSi32 [goa-1::GFP + unc-119(+)] III. GOA-1::GFP translational fusion driven by 5kb of goa-1 promoter. Rescues unc-119 locomotion defect. vsSi32 is inserted into the left arm of chromosome III between sequences 5-tttactgcatactgaacaacaggggaaaagggg-3 and 5-tagaattagctgtaagacggcgtctaggttttgca-3. Reference: Kumar S, et al. G3 (Bethesda). 2021 Aug 7;11(8):jkab167. doi: 10.1093/g3journal/jkab167. PMID: 34003969"
Proper citation: RRID:WB-STRAIN:WBStrain00050174 Copy
http://www.wormbase.org/db/get?name=WBStrain00047006
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119(ed3) III; ojIs27.
Alternate IDs: WB-STRAIN:WH337
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00047006 Copy
http://www.wormbase.org/db/get?name=WBStrain00044397
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: ltSi1 II; unc-119(ed3) III.
Alternate IDs: CGC_OD334
Notes: Generated based on CalTech XREF data|"ltSi1 [knl-1p::knl-1(re-encoded)::RFP + Cbr-unc-119(+)] II. KNL-1::RFP has been re-coded to be knl-1(RNAi) resistant. Reference: Espeut J, et al. Cell Rep. 2015 Jul 7;12(1):58-65. doi: 10.1016/j.celrep.2015.05.039. PMID: 26119738"|"Made_by: Arshad Desai lab"
Proper citation: RRID:WB-STRAIN:WBStrain00044397 Copy
http://www.wormbase.org/db/get?name=WBStrain00044684
Source Database: WormBase (WB)
Affected Genes: WBGene00004976(spe-41)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00004976(spe-41), WBGene00006843(unc-119)
Availability: unknown
Synonyms: yokSi3 II; spe-41(sy693) unc-119(ed3) III.
Notes: Generated based on CalTech XREF data|"yokSi3 [spe-11p::trp-3A::TagRFP-T::tbb-2 3'UTR + Cbr-unc-119(+)] II. Reference: Takayama J & Onami S. Cell Rep. 2016 Apr 19;15(3):625-637."
Proper citation: RRID:WB-STRAIN:WBStrain00044684 Copy
http://www.wormbase.org/db/get?name=WBStrain00005636
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(e2488) III; dnIs24.
Alternate IDs: WB-STRAIN:DE130, CGC_DE130
Notes: dnIs24 [sup46::flag::mCherry + Cbr-unc-119(+)]; site of integration unknown. Strong nuclear-localized mCherry.
Proper citation: RRID:WB-STRAIN:WBStrain00005636 Copy
http://www.wormbase.org/db/get?name=WBStrain00005633
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00045383(sup-46)
Genomic Alteration: WBGene00006843(unc-119), WBGene00045383(sup-46)
Availability: available
Synonyms: sup-46(qa710) I; dnSi4 II; unc-119(ed9) III.
Alternate IDs: WB-STRAIN:DE112, CGC_DE112
Notes: dnSi4 [gna-1::GFP::gna-1 3UTR + Cbr-unc-119(+)] inserted into ttTi5605 on LG II. Unknown if unc-119(ed9) III is homozygous or heterozygous in this strain.|"Made_by: Mark Sever"
Proper citation: RRID:WB-STRAIN:WBStrain00005633 Copy
http://www.wormbase.org/db/get?name=WBStrain00005665
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; tnIs13 V.
Alternate IDs: WB-STRAIN:DG2102, CGC_DG2102
Notes: tnIs13 [pie-1p::vab-1::GFP + unc-119(+)].
Proper citation: RRID:WB-STRAIN:WBStrain00005665 Copy
http://www.wormbase.org/db/get?name=WBStrain00005838
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: ttTi5605 II; unc-119(ed3) III; uwaEx1.
Alternate IDs: WB-STRAIN:DLM1, CGC_DLM1
Notes: uwaEx1 [eft-3p::CERULEAN-VENUS::lgg-1 + unc-119(+)]. Pick non-Unc to maintain. Ubiquitously-expressed lgg-1 tagged with oxCerulean-oxVenus double fluorescent protein (dFP) for monitoring autophagy. Reference: Chapin H, et al. Aging (Albany NY). 2015 Jun;7(6):419-34.
Proper citation: RRID:WB-STRAIN:WBStrain00005838 Copy
http://www.wormbase.org/db/get?name=WBStrain00005847
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: uwaSi5 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:DLM10, CGC_DLM10
Notes: uwaSi5 [myo-3p::CERULEAN-VENUS::lgg-1 + unc-119(+)] II. MosSCI insertion into ttTi5605 II. lgg-1 tagged with oxCerulean-oxVenus double fluorescent protein (dFP) for monitoring autophagy in body wall muscle. Reference: Chapin H, et al. Aging (Albany NY). 2015 Jun;7(6):419-34.
Proper citation: RRID:WB-STRAIN:WBStrain00005847 Copy
http://www.wormbase.org/db/get?name=WBStrain00005843
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: uwaSi3 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:DLM6, CGC_DLM6
Notes: uwaSi3 [dpy-7p::CERULEAN-VENUS::lgg-1 + unc-119(+)] II. MosSCI insertion into ttTi5605 II. lgg-1 tagged with oxCerulean-oxVenus double fluorescent protein (dFP) for monitoring autophagy in the hypodermis. Reference: Chapin H, et al. Aging (Albany NY). 2015 Jun;7(6):419-34.
Proper citation: RRID:WB-STRAIN:WBStrain00005843 Copy
http://www.wormbase.org/db/get?name=WBStrain00005842
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: ttTi5605 II; unc-119(ed3) III; uwaEx3.
Alternate IDs: WB-STRAIN:DLM5, CGC_DLM5
Notes: uwaEx3 [dpy-7p::CERULEAN-VENUS::lgg-1 + unc-119(+)]. Pick non-Unc to maintain. lgg-1 tagged with oxCerulean-oxVenus double fluorescent protein (dFP) for monitoring autophagy in the hypodermis. Reference: Chapin H, et al. Aging (Albany NY). 2015 Jun;7(6):419-34.
Proper citation: RRID:WB-STRAIN:WBStrain00005842 Copy
http://www.wormbase.org/db/get?name=WBStrain00005841
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: uwaSi2 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:DLM4, CGC_DLM4
Notes: uwaSi2 [vha-6p::CERULEAN-VENUS::lgg-1 + unc-119(+)] II. MosSCI insertion into ttTi5605 II. lgg-1 tagged with oxCerulean-oxVenus double fluorescent protein (dFP) for monitoring autophagy in the intestines. Reference: Chapin H, et al. Aging (Albany NY). 2015 Jun;7(6):419-34.
Proper citation: RRID:WB-STRAIN:WBStrain00005841 Copy
http://www.wormbase.org/db/get?name=WBStrain00005840
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: ttTi5605 II; unc-119(ed3) III; uwaEx2.
Alternate IDs: WB-STRAIN:DLM3, CGC_DLM3
Notes: uwaEx2 [vha-6p::CERULEAN-VENUS::lgg-1 + unc-119(+)]. Pick non-Unc to maintain. lgg-1 tagged with oxCerulean-oxVenus double fluorescent protein (dFP) for monitoring autophagy in the intestines. Reference: Chapin H, et al. Aging (Albany NY). 2015 Jun;7(6):419-34.
Proper citation: RRID:WB-STRAIN:WBStrain00005840 Copy
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