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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00004984
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00006744(unc-4)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00006744(unc-4)
Availability: available
Source References: EMPTY
Synonyms: unc-4(e120)/mIn1 [dpy-10(e128) umnIs43] II.
Alternate IDs: WB-STRAIN:CGC53, CGC_CGC53
Notes: umnIs43 [myo-2p::mKate2 + NeoR, II: 11755713 (intergenic)] II. Heterozygotes are wild-type mKate2+, and segregate wild-type mKate2, Unc-4 non-mKate2, and Dpy mKate2+ mIn1 homozygotes. Maintain by picking wild-type mKate2+ and check for correct segregation of progeny to maintain. Derived by insertion of myo-2p::mKate2 transgene into mIn1 balancer in parental strain DR1785 using CRISPR/Cas9.
Proper citation: RRID:WB-STRAIN:WBStrain00004984 Copy
http://www.wormbase.org/db/get?name=WBStrain00004982
Source Database: WormBase (WB)
Affected Genes: WBGene00001063(dpy-1)
Genomic Alteration: WBGene00001063(dpy-1)
Availability: available
Source References: EMPTY
Synonyms: sC1(s2023) [dpy-1(s2170) umnIs41] III.
Alternate IDs: WB-STRAIN:CGC51, CGC_CGC51
Notes: umnIs41 [myo-2p::mKate2 + NeoR, III: 518034 (intergenic)] III. Dpy mKate2+. Derived by insertion of myo-2p::mKate2 transgene into parental strain BC4279 using CRISPR/Cas9.
Proper citation: RRID:WB-STRAIN:WBStrain00004982 Copy
http://www.wormbase.org/db/get?name=WBStrain00004918
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: sEx11128.
Alternate IDs: WB-STRAIN:CF2893, CGC_CF2893
Notes: sEx11128 [gpd-2p::GFP + (pCeh361)dpy-5(+)]. Pick GFP+ animals to maintain. Derived by outcrossing BC11128 2x to wild-type to remove dpy-5(e907). Reference: Zhang P, et al. Cell Metab. 2013 Jan 8;17(1):85-100.
Proper citation: RRID:WB-STRAIN:WBStrain00004918 Copy
http://www.wormbase.org/db/get?name=WBStrain00004916
Source Database: WormBase (WB)
Affected Genes: WBGene00000169(aqp-1)
Genomic Alteration: WBGene00000169(aqp-1)
Availability: available
Source References: EMPTY
Synonyms: aqp-1(tm2309) II.
Alternate IDs: WB-STRAIN:CF2885, CGC_CF2885
Notes: Homozygous viable, but short-lived. Reference: Lee SJ, et al. Cell Metab. 2009 Nov;10(5):379-91.|"Made_by: Seung-Jae Le"|"Mutagen:TMP+UV"|"Mutagen:TMP/UV"
Proper citation: RRID:WB-STRAIN:WBStrain00004916 Copy
http://www.wormbase.org/db/get?name=WBStrain00004917
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: sEx10466.
Alternate IDs: WB-STRAIN:CF2892, CGC_CF2892
Notes: sEx10466 [nnt-1p::GFP + (pCeh361)dpy-5(+)]. Pick GFP+ animals to maintain. Derived by outcrossing BC10466 2x to wild-type to remove dpy-5(e907). Reference: Zhang P, et al. Cell Metab. 2013 Jan 8;17(1):85-100.
Proper citation: RRID:WB-STRAIN:WBStrain00004917 Copy
http://www.wormbase.org/db/get?name=WBStrain00004910
Source Database: WormBase (WB)
Affected Genes: WBGene00001609(glp-1)|WBGene00013955(kri-1)
Genomic Alteration: WBGene00001609(glp-1), WBGene00013955(kri-1)
Availability: available
Source References: EMPTY
Synonyms: kri-1(ok1251) I; glp-1(e2141) III; muEx353.
Alternate IDs: WB-STRAIN:CF2310, CGC_CF2310
Notes: muEx353 [kri-1(cDNA, a-isoform)::GFP + odr-1p::RFP]. Pick RFP+ to maintain. Temperature sensitive. Sterile at 25C; maintain at 15-20C. Reference: Berman JR and Kenyon C. Cell. 2006 Mar 10;124(5):1055-68.
Proper citation: RRID:WB-STRAIN:WBStrain00004910 Copy
http://www.wormbase.org/db/get?name=WBStrain00004998
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00001076(dpy-17)|WBGene00006744(unc-4)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00001076(dpy-17), WBGene00006744(unc-4)
Availability: available
Source References: EMPTY
Synonyms: mT1/unc-4(e120) II; mT1 [dpy-10(e128) umnIs54]/dpy-17(e164) III.
Alternate IDs: WB-STRAIN:CGC68, CGC_CGC68
Notes: umnIs54 [myo-2p::GFP + NeoR, II: 11755713 (intergenic)] III. Heterozygotes are wild-type GFP+, and segregate wild-type GFP+, DpyUnc non-mGFP, sterile Dpy GFP+ mT1 homozygotes, and large numbers of arrested aneuploid embryos. Maintain by picking wild-type GFP+ and check for correct segregation of progeny to maintain. Derived by insertion of myo-2p::GFP transgene into mT1 balancer in parental strain DR1832 using CRISPR/Cas9.
Proper citation: RRID:WB-STRAIN:WBStrain00004998 Copy
http://www.wormbase.org/db/get?name=WBStrain00004996
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00001076(dpy-17)|WBGene00006744(unc-4)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00001076(dpy-17), WBGene00006744(unc-4)
Availability: available
Source References: EMPTY
Synonyms: unc-4(e120)/mT1 [umnIs52] II; mT1 [dpy-10(e128)]/dpy-17(e164) III.
Alternate IDs: WB-STRAIN:CGC66, CGC_CGC66
Notes: umnIs52 [myo-2p::mKate2 + NeoR, III: 8856215 (intergenic)] II. Heterozygotes are wild-type mKate2+, and segregate wild-type mKate2+, DpyUnc non-mKate2, sterile Dpy mKate2+ mT1 homozygotes, and large numbers of arrested aneuploid embryos. Maintain by picking wild-type mKate2+ and check for correct segregation of progeny to maintain. Derived by insertion of myo-2p::mKate2 transgene into mT1 balancer in parental strain DR1832 using CRISPR/Cas9.
Proper citation: RRID:WB-STRAIN:WBStrain00004996 Copy
http://www.wormbase.org/db/get?name=WBStrain00004994
Source Database: WormBase (WB)
Affected Genes: WBGene00001066(dpy-4)|WBGene00006766(unc-30)
Genomic Alteration: WBGene00001066(dpy-4), WBGene00006766(unc-30)
Availability: available
Source References: EMPTY
Synonyms: unc-30(e191) dpy-4(e1166) IV; yDp1 [umnIs50] (IV;V;f).
Alternate IDs: WB-STRAIN:CGC64, CGC_CGC64
Notes: umnIs50 [myo-2p::mKate2 + NeoR, V: 1005689 (intergenic)]. Animals with the Dup are wild-type mKate2+; animals that have lost the Dup are Dpy Unc mKate2-. Maintain by picking wild-type mKate2+. Derived by insertion of myo-2p::mKate2 transgene into yDp1 duplication in parental strain TY156 using CRISPR/Cas9.
Proper citation: RRID:WB-STRAIN:WBStrain00004994 Copy
http://www.wormbase.org/db/get?name=WBStrain00004993
Source Database: WormBase (WB)
Affected Genes: WBGene00001073(dpy-11)|WBGene00006745(unc-5)
Genomic Alteration: WBGene00001073(dpy-11), WBGene00006745(unc-5)
Availability: available
Source References: EMPTY
Synonyms: unc-5(e53)/nT1 [umnIs49] IV; dpy-11(e224)/nT1 V.
Alternate IDs: WB-STRAIN:CGC63, CGC_CGC63
Notes: umnIs49 [myo-2p::mKate2 + NeoR, V: 1005689 (intergenic)] IV. Heterozygotes are wild-type mKate2+, and segregate wild-type mKate2+, DpyUnc, Vul mKate2+ (nT1) and dead eggs. Maintain by picking wild-type mKate2+. Derived by insertion of myo-2p::mKate2 transgene into nT1 balancer in parental strain MT1000 using CRISPR/Cas9.
Proper citation: RRID:WB-STRAIN:WBStrain00004993 Copy
http://www.wormbase.org/db/get?name=WBStrain00004929
Source Database: WormBase (WB)
Affected Genes: WBGene00001171(egl-2)|WBGene00001864(him-5)|WBGene00006830(unc-103)
Genomic Alteration: WBGene00001171(egl-2), WBGene00001864(him-5), WBGene00006830(unc-103)
Availability: available
Source References: EMPTY
Synonyms: unc-103(n1213) III; egl-2(rg4) him-5(e1490) V; rgEx173.
Alternate IDs: WB-STRAIN:CG490, CGC_CG490
Notes: rgEx173 [unc-103ep::egl-2(cDNA) + gtl-1p::CFP]. Pick animals with cyan fluorescence in their intestines. rgEx173 rescues food deprivation's ability to suppress unc-103(n1213)-induced male sex muscle seizures.
Proper citation: RRID:WB-STRAIN:WBStrain00004929 Copy
http://www.wormbase.org/db/get?name=WBStrain00004928
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00006779(unc-43)
Genomic Alteration: WBGene00001864(him-5), WBGene00006779(unc-43)
Availability: available
Source References: EMPTY
Synonyms: unc-43(sy574) IV; him-5(e1490) V; rgEx161.
Alternate IDs: WB-STRAIN:CG460, CGC_CG460
Notes: rgEx161[lev-11p::UNC-43g + gtl-1p::CFP]. rgEx161 rescues unc-43(sy574)-induced spicule protraction.
Proper citation: RRID:WB-STRAIN:WBStrain00004928 Copy
http://www.wormbase.org/db/get?name=WBStrain00004925
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00006779(unc-43)
Genomic Alteration: WBGene00001864(him-5), WBGene00006779(unc-43)
Availability: available
Source References: EMPTY
Synonyms: unc-43(sy574) IV; him-5(e1490) V.
Alternate IDs: WB-STRAIN:CG118, CGC_CG118
Notes: Males constitutively protract their spicules in the absence of mating cues.
Proper citation: RRID:WB-STRAIN:WBStrain00004925 Copy
http://www.wormbase.org/db/get?name=WBStrain00004920
Source Database: WormBase (WB)
Availability: available
Source References: PMID:37708127
Synonyms: muEx473.
Alternate IDs: WB-STRAIN:CF3166, CGC_CF3166
Notes: muEx473 [kin-19p::kin-19::tagRFP + tph-1p::GFP]. Pick RFP+ GFP+ animals to maintain. Low transmission rate. Translational fusion of KIN-19 displaying age-dependent aggregation. Reference: David DC, et al. PLoS Biol. 2010 Aug 10;8(8):e1000450.
Proper citation: RRID:WB-STRAIN:WBStrain00004920 Copy
http://www.wormbase.org/db/get?name=WBStrain00005002
Source Database: WormBase (WB)
Affected Genes: WBGene00003514(myo-2)|WBGene00004496(rps-27)|WBGene00006789(unc-54)|WBGene00021328(npr-23)
Genomic Alteration: WBGene00003514(myo-2), WBGene00004496(rps-27), WBGene00006789(unc-54), WBGene00021328(npr-23)
Availability: available
Source References: EMPTY
Synonyms: npr-23(umn5[LoxP + myo-2p::GFP::unc-54 3' UTR + rps-27p::neoR::unc-54 3' UTR + LoxP]) I.
Alternate IDs: WB-STRAIN:CGC72, CGC_CGC72
Notes: Homozygous viable. Deletion of 280 bp with Calarco/Colaiacovo selection cassette conferring myo-2 GFP and G418 resistance inserted at break in parental strain N2. Left flanking Sequence: AAGGCGTCATCTGGAGAGAAGAACGAAgtg ; Right flanking sequence: CGGACACTTGTGCTTCACCAACTTGATCGC. Please reference Au et al., G3 9(1): 135-144 2019 in any work resulting from use of this mutation.|"Homozygous viable. Deletion of 280 bp with Calarco/Colaiacovo selection cassette conferring myo-2 GFP and G418 resistance inserted at break. Left flanking Sequence: AAGGCGTCATCTGGAGAGAAGAACGAAgtg ; Right flanking sequence: CGGACACTTGTGCTTCACCAACTTGATCGC. Please reference Au et al., G3 9(1): 135-144 2019 in any work resulting from use of this mutation."|"Made_by: RG KO Group"|"Superficially wild-type. CRISPR/Cas9 deletion of npr-23. myo-2p::GFP + NeoR cassette is still present but may be excised using LoxP sites. Left flanking sequence: cccctgcctctggctcccacaaggcgtcatctggagagaagaacgaagtg Right flanking sequence: CGGACACTTGTGCTTCACCAACTTGATCGCGTTGCTCGTATTGGTGCCGG"
Proper citation: RRID:WB-STRAIN:WBStrain00005002 Copy
http://www.wormbase.org/db/get?name=WBStrain00005013
Source Database: WormBase (WB)
Availability: available
Source References: EMPTY
Synonyms: umnIs65 V.
Alternate IDs: WB-STRAIN:CGC84, CGC_CGC84
Notes: Made_by: Emily Lorenz-Mueller|"umnIs65 [myo-2p::mKate2 + NeoR, V:4308261 (intergenic)] V. Derived by insertion of myo-2p::mKate2 transgene into parental strain N2 using CRISPR/Cas9."
Proper citation: RRID:WB-STRAIN:WBStrain00005013 Copy
http://www.wormbase.org/db/get?name=WBStrain00005094
Source Database: WormBase (WB)
Affected Genes: WBGene00006789(unc-54)
Genomic Alteration: WBGene00006789(unc-54)
Availability: available
Source References: PMID:7568134, PMID:9751195, PMID:32966472, PMID:34707479, PMID:36226991, PMID:36653384, PMID:37103980, PMID:37522064, PMID:37113386, PMID:37549461, PMID:38983916, PMID:38991033, PMID:39950089
Synonyms: dvIs2 [Punc-54::human A-beta 3-42; pRF4 (rol-6(su1006]
Alternate IDs: WB-STRAIN:CL2006, CGC_CL2006
Notes: dvIs2 [pCL12(unc-54/human Abeta peptide 1-42 minigene) + rol-6(su1006)]. Temperature-sensitive. Maintain at 15C. Adult onset paralysis and egg-laying deficiency when raised at 20C. A few animals will be paralyzed even at permissive temperatures. Received new stock from CL 8/2005.|"WBStrain provided so WBPaper00059477 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00062076 paper added based on AFP_Strain data."|"[2020-08-03T18:23:09.013Z WBPerson324] Ressurect Strain: Paper: WBPaper00002289 Genotype: dvIs2 [Punc-54::human A-beta 3-42; pRF4 (rol-6(su1006]"
Proper citation: RRID:WB-STRAIN:WBStrain00005094 Copy
http://www.wormbase.org/db/get?name=WBStrain00005095
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)
Genomic Alteration: WBGene00001864(him-5)
Availability: available
Source References: PMID:7568134
Synonyms: unc-54p::human transthyretin::rol-6 (su1006)
Alternate IDs: WB-STRAIN:CL2008, CGC_CL2008
Notes: dvIs3 [unc-54p::human transthyretin + rol-6(su1006)]. Rollers. Him. Expression of wild-type human transthyretin (TTR) in body wall muscles. Transthyretin is secreted from the muscles into the pseudocoelom and concentrates in the coelomocytes. Reference: Link CD (1995) Proc Natl Acad Sci U S A 92:9368-9372.|"Mutagen:Gamma radiation"|"[2020-08-03T20:19:01.738Z WBPerson324] Ressurect Strain: WBPaper00002289 Genotype: unc-54p::human transthyretin::rol-6 (su1006)"
Proper citation: RRID:WB-STRAIN:WBStrain00005095 Copy
http://www.wormbase.org/db/get?name=WBStrain00005007
Source Database: WormBase (WB)
Affected Genes: WBGene00003514(myo-2)|WBGene00004496(rps-27)|WBGene00006789(unc-54)
Genomic Alteration: WBGene00003514(myo-2), WBGene00004496(rps-27), WBGene00006789(unc-54)
Availability: available
Source References: EMPTY
Synonyms: C04C3.6(umn8[LoxP + myo-2p::GFP::unc-54 3' UTR + rps-27p::neoR::unc-54 3' UTR + LoxP]) IV.
Alternate IDs: WB-STRAIN:CGC78, CGC_CGC78
Notes: Homozygous viable. Deletion of 1123 bp with Calarco/Colaiacovo selection cassette conferring myo-2 GFP and G418 resistance inserted at break in parental strain N2. Left flanking Sequence: aaaaatcaactatttttaatgaaaatttca ; Right flanking sequence: TGGTCACTTTACCTGCGTTGATATTCATGT. Please reference Au et al., G3 9(1): 135-144 2019 in any work resulting from use of this mutation.|"Homozygous viable. Deletion of 1123 bp with Calarco/Colaiacovo selection cassette conferring myo-2 GFP and G418 resistance inserted at break. Left flanking Sequence: aaaaatcaactatttttaatgaaaatttca ; Right flanking sequence: TGGTCACTTTACCTGCGTTGATATTCATGT. Please reference Au et al., G3 9(1): 135-144 2019 in any work resulting from use of this mutation."|"Made_by: RG KO Group"|"Superficially wild-type. CRISPR/Cas9 deletion of C04C3.6. myo-2p::GFP + NeoR cassette is still present but may be excised using LoxP sites. Left flanking sequence: ttgaaaatttgaaatttgaaaaaaatcaactatttttaatgaaaatttca Right flanking sequence: TGGTCACTTTACCTGCGTTGATATTCATGTTCATCGTGCTTCGAAAGTAC"
Proper citation: RRID:WB-STRAIN:WBStrain00005007 Copy
http://www.wormbase.org/db/get?name=WBStrain00005008
Source Database: WormBase (WB)
Affected Genes: WBGene00001070(dpy-8)|WBGene00003056(lon-2)|WBGene00006743(unc-3)
Genomic Alteration: WBGene00001070(dpy-8), WBGene00003056(lon-2), WBGene00006743(unc-3)
Availability: available
Source References: EMPTY
Synonyms: +/szT1 [lon-2(e678) umnIs61] I; dpy-8(e1321) unc-3(e151)/szT1 X.
Alternate IDs: WB-STRAIN:CGC79, CGC_CGC79
Notes: umnIs61 [myo-2p::mKate2 + NeoR, X: 15420938 (intergenic)] I. Heterozygotes are wild-type mKate2+, and segregate wild-type mKate2+, DpyUnc non-mKate2, dead eggs and mKate2+ Lon males. Maintain by picking wild-type mKate2+. Derived by insertion of myo-2p::mKate2 transgene into szT1 balancer in parental strain AF1 using CRISPR/Cas9.
Proper citation: RRID:WB-STRAIN:WBStrain00005008 Copy
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