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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00006381
Source Database: WormBase (WB)
Affected Genes: WBGene00000898(daf-2)
Genomic Alteration: WBGene00000898(daf-2)
Availability: available
Source References: PMID:9725835, PMID:34505574, PMID:37991448, PMID:39164296
Synonyms: daf-2(e1368) III.
Alternate IDs: WB-STRAIN:DR1572, CGC_DR1572
Notes: Maintain at 15C. Class 1 allele of daf-2. Temperature sensitive Daf-c. Adults are long-lived (Age) and exhibit extrinsic thermotolerance (Itt).
Proper citation: RRID:WB-STRAIN:WBStrain00006381 Copy
http://www.wormbase.org/db/get?name=WBStrain00006380
Source Database: WormBase (WB)
Affected Genes: WBGene00000898(daf-2)
Genomic Alteration: WBGene00000898(daf-2)
Availability: available
Source References: PMID:9725835
Synonyms: daf-2(e1371) III.
Alternate IDs: WB-STRAIN:DR1568, CGC_DR1568
Notes: Class 1 allele of daf-2. Temperature sensitive Daf-c. Maintain at 15C. Adults are long-lived (Age) and exhibit extrinsic thermotolerance (Itt).
Proper citation: RRID:WB-STRAIN:WBStrain00006380 Copy
http://www.wormbase.org/db/get?name=WBStrain00006378
Source Database: WormBase (WB)
Affected Genes: WBGene00000898(daf-2)
Genomic Alteration: WBGene00000898(daf-2)
Availability: available
Source References: EMPTY
Synonyms: daf-2(m579) III.
Alternate IDs: WB-STRAIN:DR1566, CGC_DR1566
Notes: Adults Age and Itt and temperature sensitive Unc (class 2 allele). m579 results in an amino acid substitution(R437C) in the extracellular portion of the DAF-2 receptor (specifically, the Cys-rich domain).|"Made_by: Riddle Lab"
Proper citation: RRID:WB-STRAIN:WBStrain00006378 Copy
http://www.wormbase.org/db/get?name=WBStrain00006399
Source Database: WormBase (WB)
Affected Genes: WBGene00003050(liv-4)|WBGene00004510(rrf-3)
Genomic Alteration: WBGene00003050(liv-4), WBGene00004510(rrf-3)
Availability: available
Source References: EMPTY
Synonyms: rrf-3(b26) II; liv-4(m872) V.
Alternate IDs: WB-STRAIN:DR2153, CGC_DR2153
Notes: Weak Unc (kinker) as adult. Increased life span. Maintain at 15C.
Proper citation: RRID:WB-STRAIN:WBStrain00006399 Copy
http://www.wormbase.org/db/get?name=WBStrain00006310
Source Database: WormBase (WB)
Affected Genes: WBGene00000123(ama-1)|WBGene00001074(dpy-13)|WBGene00002514(let-286)|WBGene00006745(unc-5)|WBGene00006756(unc-17)
Genomic Alteration: WBGene00000123(ama-1), WBGene00001074(dpy-13), WBGene00002514(let-286), WBGene00006745(unc-5), WBGene00006756(unc-17)
Availability: available
Source References: PMID:8608933
Synonyms: unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m118) let-286(m269) IV.
Alternate IDs: WB-STRAIN:DR717, CGC_DR717
Notes: Heterozygotes are semi-Dpy and segregate semi-Dpy, Unc and DpyLet. The DpyLet are adults which lay eggs that do not hatch. Maintain by picking semi-Dpy.
Proper citation: RRID:WB-STRAIN:WBStrain00006310 Copy
http://www.wormbase.org/db/get?name=WBStrain00006396
Source Database: WormBase (WB)
Affected Genes: WBGene00002742(let-552)|WBGene00004394(rol-1)|WBGene00006744(unc-4)
Genomic Alteration: WBGene00002742(let-552), WBGene00004394(rol-1), WBGene00006744(unc-4)
Availability: available
Source References: EMPTY
Synonyms: mIn1 [rol-1(e91)]/let-552(e2542) unc-4(e120) II.
Alternate IDs: WB-STRAIN:DR2102, CGC_DR2102
Notes: Heterozygotes are WT and segregate WT, Lethal Uncs and Roller mIn1 homozygotes. let-552 unc-4 chromosome is well balanced. Rol does not express until late L4/early adult. Pick WT and check for correct segregation of progeny.
Proper citation: RRID:WB-STRAIN:WBStrain00006396 Copy
http://www.wormbase.org/db/get?name=WBStrain00006395
Source Database: WormBase (WB)
Affected Genes: WBGene00000252(bli-2)|WBGene00001072(dpy-10)|WBGene00006744(unc-4)
Genomic Alteration: WBGene00000252(bli-2), WBGene00001072(dpy-10), WBGene00006744(unc-4)
Availability: available
Source References: EMPTY
Synonyms: mIn1 [dpy-10(e128) mIs14]/bli-2(e768) unc-4(e120) II.
Alternate IDs: WB-STRAIN:DR2078, CGC_DR2078
Notes: WT gross phenotype, with GFP semi-dominantly expressed in 4-60 cell embyros, pharyngeal muscle and gut. Segregates WT, brighter Dpy GFP mIn1 homozygotes and non-GFP bli-2 unc-4 homozygotes. Pharyngeal and gut GFP is easily seen in a UV dissecting microscope; early embryonic signal requires higher magnification. mIs14 occasionally crosses off mIn1[dpy-10], apparently by double recombination. Pick WT, check for GFP and check for correct segregation of progeny to maintain. mIs14 is ccEx9747 integrated into mIn1[dpy-10]. This is a three-construct element containing myo-2 and pes-10 promoters and a gut enhancer fused individually to GFP coding sequence.
Proper citation: RRID:WB-STRAIN:WBStrain00006395 Copy
http://www.wormbase.org/db/get?name=WBStrain00006390
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00001076(dpy-17)|WBGene00006744(unc-4)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00001076(dpy-17), WBGene00006744(unc-4)
Availability: available
Source References: EMPTY
Synonyms: mT1/unc-4(e120) II; mT1 [dpy-10(e128)]/dpy-17(e164) III.
Alternate IDs: WB-STRAIN:DR1832, CGC_DR1832
Notes: Mutagen:Gamma Rays|"WT phenotype. Segregates WT, sterile Dpy mT1 homozygotes, Unc-4;Dpy-17 and large numbers of arrested aneuploid embryos. Pick WT and check for correct segregation of progeny to maintain. This strain was generated by the Genetic Toolkit project, which should be acknowledged in any publications resulting from its use: The Genetic Toolkit is funded by the NIH National Center for Research Resources (NCRR) (USA) to Ann M. Rose, David L. Baillie, and Donald L. Riddle. Report all experimental results to Don Riddle."
Proper citation: RRID:WB-STRAIN:WBStrain00006390 Copy
http://www.wormbase.org/db/get?name=WBStrain00006309
Source Database: WormBase (WB)
Affected Genes: WBGene00000123(ama-1)|WBGene00001074(dpy-13)|WBGene00002512(let-284)|WBGene00006745(unc-5)|WBGene00006756(unc-17)
Genomic Alteration: WBGene00000123(ama-1), WBGene00001074(dpy-13), WBGene00002512(let-284), WBGene00006745(unc-5), WBGene00006756(unc-17)
Availability: available
Source References: PMID:8608933
Synonyms: unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m118) let-284(m267) IV.
Alternate IDs: WB-STRAIN:DR715, CGC_DR715
Notes: Heterozygotes are semi-Dpy and segregate semi-Dpy, Unc and DpyLet. Lethal early larval. Maintain by picking semi-Dpy.
Proper citation: RRID:WB-STRAIN:WBStrain00006309 Copy
http://www.wormbase.org/db/get?name=WBStrain00006307
Source Database: WormBase (WB)
Affected Genes: WBGene00000123(ama-1)|WBGene00001074(dpy-13)|WBGene00002506(let-277)|WBGene00006745(unc-5)|WBGene00006756(unc-17)
Genomic Alteration: WBGene00000123(ama-1), WBGene00001074(dpy-13), WBGene00002506(let-277), WBGene00006745(unc-5), WBGene00006756(unc-17)
Availability: available
Source References: PMID:8608933
Synonyms: unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m118) let-277(m262) IV.
Alternate IDs: WB-STRAIN:DR710, CGC_DR710
Notes: Heterozygotes are semi-Dpy and segregate semi-Dpys, Uncs and Lets. Lethal mid-larval. Maintain by picking semi-Dpy.
Proper citation: RRID:WB-STRAIN:WBStrain00006307 Copy
http://www.wormbase.org/db/get?name=WBStrain00006306
Source Database: WormBase (WB)
Affected Genes: WBGene00000123(ama-1)|WBGene00001074(dpy-13)|WBGene00002508(let-279)|WBGene00006745(unc-5)|WBGene00006756(unc-17)
Genomic Alteration: WBGene00000123(ama-1), WBGene00001074(dpy-13), WBGene00002508(let-279), WBGene00006745(unc-5), WBGene00006756(unc-17)
Availability: available
Source References: PMID:8608933
Synonyms: unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m118) let-279(m261) IV.
Alternate IDs: WB-STRAIN:DR709, CGC_DR709
Notes: Heterozygotes are semi-Dpy and segregate semi-Dpy, Unc and DpyLets. The DpyLets are adult steriles. Maintain by picking semi-Dpy.
Proper citation: RRID:WB-STRAIN:WBStrain00006306 Copy
http://www.wormbase.org/db/get?name=WBStrain00006304
Source Database: WormBase (WB)
Affected Genes: WBGene00000123(ama-1)|WBGene00001074(dpy-13)|WBGene00002511(let-282)|WBGene00006745(unc-5)|WBGene00006756(unc-17)
Genomic Alteration: WBGene00000123(ama-1), WBGene00001074(dpy-13), WBGene00002511(let-282), WBGene00006745(unc-5), WBGene00006756(unc-17)
Availability: available
Source References: PMID:8608933
Synonyms: unc-17(e113) unc-5(e53)/dpy-13(e184) ama-1(m118) let-282(m258) IV.
Alternate IDs: WB-STRAIN:DR705, CGC_DR705
Notes: Heterozygotes are semi-Dpy and segregate semi-Dpy, Unc and DpyLet. Lethal early larval. Maintain by picking semi-Dpy.
Proper citation: RRID:WB-STRAIN:WBStrain00006304 Copy
http://www.wormbase.org/db/get?name=WBStrain00006443
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00001102(dsh-2)|WBGene00001867(him-8)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00001102(dsh-2), WBGene00001867(him-8)
Availability: available
Source References: EMPTY
Synonyms: dsh-2(ez25)/mIn1 [mIs14 dpy-10(e128)] II; him-8(e1489) IV.
Alternate IDs: WB-STRAIN:DZ205, CGC_DZ205
Notes: Made_by: Weiru Chang|"mIs14 [myo-2p::GFP + pes-10p::GFP]. Him. Heterozygotes are WT with relatively dim pharyngeal GFP signal, and segregate WT dim GFP+ heterozygotes, Dpy bright GFP+ (mIn1 homozygotes), and Egl non-GFP ez25 homozygotes. Pick WT dim GFP and check for correct segregation of progeny to maintain."
Proper citation: RRID:WB-STRAIN:WBStrain00006443 Copy
http://www.wormbase.org/db/get?name=WBStrain00006440
Source Database: WormBase (WB)
Affected Genes: WBGene00000265(brd-1)
Genomic Alteration: WBGene00000265(brd-1)
Availability: available
Source References: EMPTY
Synonyms: brd-1(dw1) III.
Alternate IDs: WB-STRAIN:DW103, CGC_DW103
Notes: Homozygous viable. Weak Him phenotype (2-3%). Extremely sensitive to ionizing radiation and other DNA damaging agents.|"Mutagen:UVA+TMP"|"Mutagen:UVA/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00006440 Copy
http://www.wormbase.org/db/get?name=WBStrain00006439
Source Database: WormBase (WB)
Affected Genes: WBGene00000264(brc-1)
Genomic Alteration: WBGene00000264(brc-1)
Availability: available
Source References: PMID:33262405, PMID:38894809, PMID:39115289
Synonyms: brc-1(tm1145) III.
Alternate IDs: WB-STRAIN:DW102, CGC_DW102
Notes: Homozygous viable. Weak Him phenotype (2-3%). Extremely sensitive to ionizing radiation and other DNA damaging agents.|"Mutagen:UVA+TMP"|"Mutagen:UVA/TMP"|"Reference WBPaper00060693 added based on published strain data identified by Textpresso literature search."
Proper citation: RRID:WB-STRAIN:WBStrain00006439 Copy
http://www.wormbase.org/db/get?name=WBStrain00006438
Source Database: WormBase (WB)
Affected Genes: WBGene00000226(atl-1)
Genomic Alteration: WBGene00000226(atl-1)
Availability: available
Source References: EMPTY
Synonyms: atl-1(tm853) V/nT1 [unc-?(n754) let-? qIs50] (IV;V).
Alternate IDs: WB-STRAIN:DW101, CGC_DW101
Notes: Heterozygotes are Unc and GFP+ with signal in the pharynx. atl-1(tm853) homozygotes are non-Unc, viable, GFP-, and produce 100% dead embryos. qIs50 is an insertion of ccEx9747 with markers: myo-2::GFP expressed brightly in the pharynx throughout development, pes-10::GFP expressed in embryos, and a gut promoter (F22B7.9) driving GFP in the intestine. nT1[unc-?(n754) let-? qIs50] is also known as DnT1[qIs50]. qIs50 is apparently inserted on DnT1. qIs50 is somewhat dimmer than the similar qIs51.|"Made_by: Mitani/Garcia-Muse"|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00006438 Copy
http://www.wormbase.org/db/get?name=WBStrain00006437
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00004752(sec-5)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00004752(sec-5)
Availability: available
Source References: EMPTY
Synonyms: sec-5(pk2357)/mIn1 [dpy-10(e128) mIs14] II.
Alternate IDs: WB-STRAIN:DV2689, CGC_DV2689
Notes: Heterozygotes segregate wild-type GFP+ heterozygotes, GFP+ Dpy, and sec-5 homozygotes (scrawny, small broods, abnormal gut appearance) sec-5 is homozygous maternal-effect lethal; M+Z- animals produce a few dead L1-L2 stage larvae with Vab defects. Pick GFP+ wild-type to maintain. Based upon phenotype, pk2357 is a strong loss-of-function, but likely not a null allele; molecular lesion produces a premature stop at position 389. Reference: Frische EW, et al. EMBO J. 2007 Dec 12;26(24):5083-92. [NOTE: This strain was previously described as carrying pk2358, but pk2357 is the correct allele. Both pk2357 and pk2358 cause the same nonsense (amber) change.]
Proper citation: RRID:WB-STRAIN:WBStrain00006437 Copy
http://www.wormbase.org/db/get?name=WBStrain00006436
Source Database: WormBase (WB)
Affected Genes: WBGene00000898(daf-2)|WBGene00001076(dpy-17)
Genomic Alteration: WBGene00000898(daf-2), WBGene00001076(dpy-17)
Availability: available
Source References: EMPTY
Synonyms: daf-2(e1370) dpy-17(e164) III.
Alternate IDs: WB-STRAIN:DV2275, CGC_DV2275
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00006436 Copy
http://www.wormbase.org/db/get?name=WBStrain00006435
Source Database: WormBase (WB)
Affected Genes: WBGene00006826(unc-97)
Genomic Alteration: WBGene00006826(unc-97)
Availability: available
Source References: EMPTY
Synonyms: unc-97(su110) X.
Alternate IDs: WB-STRAIN:DV2208, CGC_DV2208
Notes: Made by outcrossing HE110 four times. su110 is moderately Smg suppressible: HE110 animals are significantly less Unc than DV2208, and HE110 animal are also pVul, which is characteristic of Smg mutations.
Proper citation: RRID:WB-STRAIN:WBStrain00006435 Copy
http://www.wormbase.org/db/get?name=WBStrain00006453
Source Database: WormBase (WB)
Affected Genes: WBGene00006604(tra-1)
Genomic Alteration: WBGene00006604(tra-1)
Availability: available
Source References: EMPTY
Synonyms: tra-1(ez72[biotag::GFP::TEV::3xflag::tra-1]) III; zuIs236.
Alternate IDs: WB-STRAIN:DZ841, CGC_DZ841
Notes: tra-1(ez72[biotag::GFP::TEV::3xflag::tra-1]) III. zuIs236 [his-72(1 kb 5'UTR)::BIRA::GFP::his-72(1 kb 3'UTR) + unc-119(+)]. Location of zuIs236 is not known, but is not in LG III.
Proper citation: RRID:WB-STRAIN:WBStrain00006453 Copy
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