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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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SS-Rbm20em10Mcwi Resource Report Resource Website |
RRID:RGD_11553881 | Rattus norvegicus | ZFN system was used to introduce a mutation in the Rbm20 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 13-bp deletion in Exon 2 of the Rbm20 gene. Contact MCW rat distribution at [email protected] | 11553881 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2017-01-26) | 11553881 | RGD | 2026-10-17 01:54:00 | 0 | |||||
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SS-Axlem2Mcwi Resource Report Resource Website |
RRID:RGD_12790604 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Axl gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 32-bp deletion in the exon 2 of the Axl gene. Contact MCW rat distribution at [email protected] | 12790604 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 12790604 | RGD | 2026-10-17 01:54:00 | 0 | |||||
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SS-Axlem1Mcwi Resource Report Resource Website |
RRID:RGD_12790602 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Axl gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 31-bp deletion in the exon 2 of the Axl gene. Contact MCW rat distribution at [email protected] | 12790602 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 12790602 | RGD | 2026-10-17 01:54:00 | 0 | |||||
|
NMC/Nrs Resource Report Resource Website |
RRID:RGD_11565100 | Rattus norvegicus | This strain was found in a colony of F344.LEC-xhs1/1Nrs (NBRP Rat No: 0293). As to radiosensitivity gene, D4Nirs8-D4Rat45 region is LEC type. Affected females with dominant gene on Chr10 develop mammary gland cancer after pregnancy (histological type is undetermined). In many cases, this neoplastis lesion resolve spontaneously after delivery. No homozygous female is obtained at this time. Affected male rats don't show any phenotype. National BioResource Project for the Rat in Japan | 11565100 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2016-11-18) | 11565100 | RGD | 2026-10-17 01:54:01 | 0 | |||||
|
SS.BN-(D13Rat25-rs198199323)-Btg2em24Mcwi Resource Report Resource Website |
RRID:RGD_12437071 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 2-bp insertion in the exon 1 in the Btg2 gene of SS.BN-(D13Rat25-rs198199323)/Mcwi rat embryos. Contact MCW rat distribution at [email protected] | 12437071 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 12437071 | RGD | 2026-10-17 01:54:01 | 0 | |||||
|
SD-Grm5em1Sage Resource Report Resource Website |
RRID:RGD_11568067 | Rattus norvegicus | The ZFN mutant rat strain was produced by injecting zinc finger nuclease targeting rat Grm5 into Sprague Dawley embryos. The resulting mutation was a knockout of Grm5 demonstrated by western blot. Horizon Discovery | 11568067 | mutant | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Embryo (as of 2016-12-13) | 11568067 | RGD | 2026-10-17 01:54:00 | 0 | |||||
|
SS-Sorcs2em7Mcwi Resource Report Resource Website |
RRID:RGD_12790947 | Rattus norvegicus | This strain was produced by injecting ZFNs targeting the sequence of Sorcs2 into SS/JrHsdMcwi rat embryos. The resulting mutation is a 33-bp frameshift deletion in exon 15. | 12790947 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2017-02-22) | 12790947 | RGD | 2026-10-17 01:54:00 | 0 | |||||
|
SS-Pon3em1Mcwi Resource Report Resource Website |
RRID:RGD_12790702 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Pon3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 16-bp deletion of exon 4 in the Pon1 gene. Contact MCW rat distribution at [email protected] | 12790702 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 12790702 | RGD | 2026-10-17 01:54:01 | 0 | |||||
|
W-Ift140em1Kyo Resource Report Resource Website |
RRID:RGD_12879432 | Rattus norvegicus | This strain was established by CRISPR/Cas9 system at Kyoto University and introduced to the Institute of Environmental Toxicology. Background strain: Jcl:Wistar. This line 1 (em1) has 2-bp insertion (c.23_24insGG) in the exon 1 of Ift140 (intraflagellar transport 140) gene. National BioResource Project for the Rat in Japan | 12879432 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2017-04-19) | 12879432 | RGD | 2026-10-17 01:54:02 | 0 | |||||
|
W-Ift140em2Kyo Resource Report Resource Website |
RRID:RGD_12879434 | Rattus norvegicus | This strain was established by CRISPR/Cas9 system at Kyoto University and introduced to the Institute of Environmental Toxicology. Background strain: Jcl:Wistar. This line 2 (em2) has 2-bp deletion (c.23_24del) in the exon 1 of Ift140 (intraflagellar transport 140) gene. National BioResource Project for the Rat in Japan | 12879434 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2017-04-19) | 12879434 | RGD | 2026-10-17 01:54:02 | 0 | |||||
|
F344-Rag2em1Sage Resource Report Resource Website |
RRID:RGD_12904905 | Rattus norvegicus | This ZFN model carries a 2 bp deletion within exon 3 of the Rag2 gene.on chromosome 3 Rag2 knockout rats completely lack B and T cells. Horizon Discovery | 12904905 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2017-05-24) | 12904905 | RGD | 2026-10-17 01:54:02 | 0 | |||||
|
SD-Prkdcem1Sage Resource Report Resource Website |
RRID:RGD_12904907 | Rattus norvegicus | This ZFN induced knockout rats carrying a shorter truncated gene, 872 by PCR vs 1627 in wild type, have severe combined immunodeficiency (SCID) and lack of both B and T cells Horizon Discovery | 12904907 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-24) | 12904907 | RGD | 2026-10-17 01:54:02 | 0 | |||||
|
SS-Shc1em5Mcwi Resource Report Resource Website |
RRID:RGD_11553916 | Rattus norvegicus | ZFN system was used to introduce a T>G transversion mutation in the Shc1 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a substitution to generate S36A in Exon 2 of theShc1 gene. Contact MCW rat distribution at [email protected] | 11553916 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-01-25) | 11553916 | RGD | 2026-10-17 01:54:01 | 0 | |||||
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SD-Ldlrem1Sage Resource Report Resource Website |
RRID:RGD_12904908 | Rattus norvegicus | In this ZFN induced model, a total of 337 bp were deleted at the junction of intron 3 and exon 4 (on chromosome 8), and 4 bp ccgt were inserted rat Ldlr gene on chromosome 8. Homozygous knockout rats display loss of LDLR protein via Western blot. Homozygous knockout rats have increased body weight as compared to wild type. Homozygous knockout rats show significantly elevated serum cholesterol levels. Horizon Discovery | 12904908 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-24) | 12904908 | RGD | 2026-10-17 01:54:01 | 0 | |||||
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SS-Nlrp10em2Mcwi Resource Report Resource Website |
RRID:RGD_13207501 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Nlrp10 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 11-bp deletion of exon 2 in the Nlrp10 gene. Contact MCW rat distribution at [email protected] | 13207501 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13207501 | RGD | 2026-10-17 01:54:02 | 0 | |||||
|
SS-Renem1Mcwi+/- Resource Report Resource Website |
RRID:RGD_12743611 | Rattus norvegicus | ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous | 12743611 | mutant | Rat Genome Database (RGD) | RGD | Live Animals; Cryopreserved Sperm (as of 2018-09-05) | 12743611 | RGD | 2026-10-17 01:54:01 | 0 | |||||
|
SD-Ahrem1Sage Resource Report Resource Website 1+ mentions |
RRID:RGD_12903250 | Rattus norvegicus | This ZFN model contains a 760-bp deletion in the rat Ahr gene. Horizon Discovery | 12903250 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-10) | 12903250 | RGD | 2026-10-17 01:54:02 | 1 | |||||
|
LE-Slc32a1tm1(cre)Sage Resource Report Resource Website 50+ mentions |
RRID:RGD_12905033 | Rattus norvegicus | This model expresses cre-recombinase under the control of the endogenous solute carrier family 32 member 1 (Vgat) promoter enabling specific expression in Vgat positive GABAergic neurons. This model possesses a targeted insertion of (IRES)-cre immediately after the translational stop in the open reading frame of the Vgat gene. The Vgat-Cre rat is useful for applications requiring tissue specific expression, including optogenetics and breeding with transgenic floxed lines. Horizon Discovery | 12905033 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-31) | 12905033 | RGD | 2026-10-17 01:54:02 | 92 | |||||
|
LE-Viptm1(cre)Sage Resource Report Resource Website |
RRID:RGD_12905034 | Rattus norvegicus | This model expresses cre-recombinase under the control of the endogenous vasoactive intestinal peptide (VIP) promoter enabling specific expression in VIP positive GABAergic interneurons. This model possesses a targeted insertion of (T2A)-cre immediately before the translational stop in the open reading frame of the VIP gene. The VIP-Cre rat is useful for applications requiring tissue specific expression, including optogenetics and breeding with transgenic floxed lines. Horizon Discovery | 12905034 | mutant | Rat Genome Database (RGD) | RGD | Unknown (as of 2017-05-31) | 12905034 | RGD | 2026-10-17 01:54:02 | 0 | |||||
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SD-Slc6a3tm1(cre)Sage Resource Report Resource Website 1+ mentions |
RRID:RGD_12905031 | Rattus norvegicus | This model expresses cre-recombinase under the control of the endogenous dopamine transporter promoter enabling specific expression in dopaminergic neurons. This model possesses a targeted insertion of (IRES)-cre immediately after the translational stop in the open reading frame of DAT. The DAT-Cre rat is useful for applications requiring tissue specific expression, including optogenetics and breeding with transgenic floxed lines. Horizon Discovery | 12905031 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-31) | 12905031 | RGD | 2026-10-17 01:54:02 | 3 |
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