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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
∆HTB1 gl 9.4 Resource Report Resource Website |
RRID:TSC_SD02080 | Tetrahymena thermophila | This is the HTB1 germline KO homozygous heterokaryon. The 9.* series have different mating type from 11.* series. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTB1 (TTHERM_00633360) | Micronucleus: Neo2 into HTB1 replacing coding | SD02080 | htb1[∆::neo2]/htb1[∆::neo2] (mp-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:19822522 | 2025-04-20 03:37:31 | 0 | ||||
|
122∆5.3ns Resource Report Resource Website |
RRID:TSC_SD01791 | Tetrahymena thermophila | IFT122 KO heterokaryon, this is the non- star side From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | IFT122 (TTHERM_00694540) | Micronucleus: Neo3 into coding of IFT122A | SD01791 | ift122[∆::neo3]/ift122[∆::neo3] (WT; pm-?, mp-?, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:18211962 PMID:18199688 |
2025-04-20 03:37:31 | 0 | ||||
|
CU3081 Resource Report Resource Website |
RRID:TSC_SD01031 | Tetrahymena thermophila | SD01031 | chx1-1/chx1-1; pmr1-1/pmr1-1; Nulli 3 (CHX1; pmr1-1; cy-s, pm-r, II) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:31 | 0 | ||||||||
|
1235D-1(BTU1) Resource Report Resource Website |
RRID:TSC_SD02122 | Tetrahymena thermophila | Progeny of DB6B x DB2A, transformed by BTU1-1235D mutation construct (E431,432,433,435D) From the Gorovsky lab, University of Rochester. | BTU1 (TTHERM_00348510), BTU2 (TTHERM_00836580) | Micronucleus: knockout of btu1 with neo knockout of btu2 with bsr Macronucleus: BTU1 has only (E431, 432, 433, 435D) no WT | SD02122 | btu1-?[∆::neo1]/ btu1-?[∆::neo1]; btu2-?[∆::bsr1]/ btu2-?[∆::bsr1]; CHX1/CHX1; mpr1-1/mpr1-1 or MPR1/MPR1 (btu2-?[∆::bsr1]; btu1-?[∆::neo1]/ btu1-? [E431D,E432D,E433D,E435D]; pm-r) | TSC, Tetrahymena Stock Center | TSC | PMID:10831613 | 2025-04-20 03:37:31 | 0 | ||||
|
HA-His-hv2(5) Resource Report Resource Website |
RRID:TSC_SD02643 | Tetrahymena thermophila | HA-His-tagged hv2 transformant. Checked by western blot. HA-His-hv2 is expressed. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHT3 (TTHERM_00016170) | Macronucleus: N-terminal HA-His- tag of HHT3, not sure if complete replacement | SD02643 | mpr1-1/mpr1-1 (?HHT3/hht3[3’neo2, HA-His-n]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 PMID:9343391 |
2025-04-20 03:37:31 | 0 | ||||
|
htb1-K4Q-B8b Resource Report Resource Website |
RRID:TSC_SD02091 | Tetrahymena thermophila | ∆∆HTB knockout heterokaryons rescued by htb1-K4Q. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTB1 (TTHERM_00633360), HTB2 (TTHERM_00283180) | Micronucleus: neo2 KO of HTB1 and HTB2 coding Macronucleus: Mutated HTB1 with K4Q | SD02091 | htb1[∆::neo2]/htb1[∆::neo2]; htb2 [∆::neo2]/htb2 [∆::neo2] (htb1[∆::neo2]/htb1[K4Q] ; htb2 [∆::neo2]; pm-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:19822522 | 2025-04-20 03:37:32 | 0 | ||||
|
CU3089 Resource Report Resource Website |
RRID:TSC_SD01040 | Tetrahymena thermophila | Deletion on left arm of chromosome 3. | SD01040 | chx1-1/chx1-1; pmr1-1/pmr1-1; Del 3L (CHX1; pmr1-1; cy-s, pm-r, II) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:32 | 0 | |||||||
|
20469-4 Resource Report Resource Website |
RRID:TSC_SD01564 | Tetrahymena thermophila | Collected by Paul Doerder on 7/25/2009 from the pond designated Childs Bog in Harrisville, NH (lat. 42 57.763, long. -72 07.451, elevation 1388 ft, nearest road is Silver Lake Rd / Nelson). Geographical area: New England Collection number: 1187 Has a micronucleus. | SD01564 | (IV) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:31 | 0 | |||||||
|
HTA1-G1 14B7 Resource Report Resource Website |
RRID:TSC_SD02811 | Tetrahymena thermophila | HTA1 Germline knockout heterokaryon. Transformed CU428 X B2086 with pQR10B (removes all coding, replaces with neo cassette. It can mate with HTA1 G1 15B. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTA1 (TTHERM_00790790) | SD02811 | hta1[∆::neo2]/hta1[∆::neo2; CHX!/CHX1; mpr1?/mpr1? (mp-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:12665578 PMID:11430834 |
2025-04-20 03:37:32 | 0 | |||||
|
BLT-Bbc-HA #12 Resource Report Resource Website |
RRID:TSC_SD02260 | Tetrahymena thermophila | CU428 with BLT/BTU1 chimeric gene in MTT1 locus with HA tag. CU428 somatic transformant with pBbc-8 construct. BLT1(AA 1-428) with BTU1 at C-terminus (AA 429-443) followed by HA tag, inserted into the MTT1 locus. Neo2 upstream From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | BLT1 (TTHERM_01104960) | Macronucleus: BLT1(AA 1-428) withBTU1 at C terminus (AA 429-443) followed by HA tag, inserted into the MTT1 locus. Neo2 upstreamin MTT1 5’ region | SD02260 | mpr1-1/mpr1-1 (MTT1/mtt1-1[5’neo2,∆,HAc(::BLT11-4288,BTU1429-443)], VII) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:31 | 0 | |||||
|
IA375 Resource Report Resource Website |
RRID:TSC_SD01572 | Tetrahymena thermophila | Close to additive expression. However, the abnormalities of cytokinesis caused by expression of cdaK-1 are not as pronounced around the secondary oral meridian as they are around the primary orial meridian of janus-expressing cells. A clone with high expression of janA was selected, making the inclusion of eja1-1 likely. Submitted by Joseph Frankel, University of Iowa | JANA (janusA), EJA1 (enhancer of janA), CDAK (cell division arrest K) | SD01572 | janA-1/janA-1; eja1-1/eja1-1; cdaK-1/cdaK-1 (janA-1; eja1-1; cdaK-1; janA, eja1,cdaK1, VII) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:32 | 0 | ||||||
|
IA443 Resource Report Resource Website |
RRID:TSC_SD01455 | Tetrahymena thermophila | Complex phenotype with contractile vacuole pores too close to the oral apparatus, and clockwise slippage of oral primordia. The phenotype becomes more extreme (with misshapen cells) after prolonged incubation at elevated temperatures. Allelic to hpo1-1 (IA466) Submitted by Joseph Frankel, University of Iowa | HPO1 (hypoangular) | SD01455 | hpo1-3/hpo1-3 (hpo1-3, II) | TSC, Tetrahymena Stock Center | TSC | PMID:8253268 | 2025-04-20 03:37:31 | 0 | |||||
|
IA437 Resource Report Resource Website |
RRID:TSC_SD01576 | Tetrahymena thermophila | The sister clone (IA436,now extinct) manifests joint expression of the two mutations, which can be roughly summarized as the "...janus phenotype being superimposed on the hypoangular body plan". Submitted by Joseph Frankel, University of Iowa | JANC (janusC), HPO1(hypoangular1) | SD01576 | janC-1/janC-1; hpo1-2/hpo1-2 (janC-1; hpo1-2; janC, hpo1, IV) | TSC, Tetrahymena Stock Center | TSC | PMID:18658256 | 2025-04-20 03:37:31 | 0 | |||||
|
Nol1KO C11-11-C10 Resource Report Resource Website |
RRID:TSC_SD02704 | Tetrahymena thermophila | Heterozygous heterokaryon. WAG1 KO, mates with Nol1 KO C11-9-A5-A4 Named NOL1 until found there was already a gene of that name. Re-named WAG1. From the Gorovsky lab, University of Rochester. | WAG1 (TTHERM_00299879) | Micronucleus: Neo3 knockout of WAG1, heterozygous | SD02704 | wag1[∆::neo3]/wag1[∆::neo3] (?) | TSC, Tetrahymena Stock Center | TSC | PMID:19596782 | 2025-04-20 03:37:31 | 0 | ||||
|
VI004 Resource Report Resource Website |
RRID:TSC_SD01739 | Tetrahymena thermophila | The knockout also introduces a frameshift mutation. The knockout has been confirmed by paromomycin resistance, but macronuclear allele homozygosity has not been verified. The neo4-KanR2 knockout cassette was generated by cloning fragments of the pNeo4 plasmid's neo4 cassette and the pUC4K plasmid's KanR2 cassette. The KanR2 gene was used for E. coli transformation and is not a selectable marker in Tetrahymena. Submitted by Robert Coyne, J. Craig Venter Institute | JMJ2 (TTHERM_00455500) | Micronucleus: PAR1 gene partially replaced by neo4-KanR2 cassette. Macronucleus: JMJ2 gene partially replaced by neo4-KanR2 cassette. | SD01739 | (JMJ2/jmj2-1[Δ21-672(::neo4, KanR2)]; pm-r, II) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:30 | 0 | |||||
|
IA412 Resource Report Resource Website |
RRID:TSC_SD00649 | Tetrahymena thermophila | SD00649 | mpr1-1/mpr1-1; bcd1-1/bcd1-1 (bcd1-1; mpr1-1; bcd1, mp-r, II) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:31 | 0 | ||||||||
|
c∆SAI 2- 9-1-Mtt-DCL1-1 Resource Report Resource Website |
RRID:TSC_SD02278 | Tetrahymena thermophila | homozygous homokaryon of ∆DCL1 (c∆SAI2 9-1) ,neo 3 was deleted in mac and .assorted to pm-s; with MTTi locus replaced with MTT1-DCL1 construct. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | DCL1 (TTHERM_00284230) | Micronucleus: homozygous neo3 KO of DCL1, Macronucleus: homozygous ∆DCL1, neo 3 was deleted in mac and assorted to pm-s, MTT1-DCL1 replaced some of MTT1 | SD02278 | dcl1[∆?::neo3]/dcl1[∆?::neo3] (dcl1[∆?]; MTT1[∆::DCL1]; mp-?, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:15598983 | 2025-04-20 03:37:33 | 0 | ||||
|
HTA3-G305A1 Resource Report Resource Website |
RRID:TSC_SD02673 | Tetrahymena thermophila | HTA3 germline knockout heterokaryon. Transformed CU428 X B2086 with pQR22 (remove all coding by neo cassette). It can mate with G308A3 and G304A1, From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTA3 (TTHERM_00143660) | Micronucleus: neo2 into HTAZ coding | SD02673 | htaz[∆::neo2]/htaz[∆::neo2]; mpr1-1/MPR1-1? (mpr1-1/MPR1-1?; mp-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:12665578 PMID:11430834 |
2025-04-20 03:37:33 | 0 | ||||
|
CU508 Resource Report Resource Website |
RRID:TSC_SD00257 | Tetrahymena thermophila | SD00257 | chx1-1/CHX1; MPR1/mpr1-1; H1(neo)/+ (chx1-1/CHX1; MPR1/mpr1-1; cy-r, mp-r, pm-r, II) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:32 | 0 | ||||||||
|
RNH1.3 sKO (7)-13-1 Resource Report Resource Website |
RRID:TSC_SD02712 | Tetrahymena thermophila | Somatic KO of RNH1.3 , neo3, CU427 background. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | RNH13 (TTHERM_00283900) | Macronucleus: Neo3 knockout of RNH1.3 | SD02712 | chx1-1/chx1-1 (rnh1.3-1[∆::neo3]; pm-r, VI) | TSC, Tetrahymena Stock Center | TSC | 2025-04-20 03:37:32 | 0 |
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