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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00004056
Source Database: WormBase (WB)
Availability: available
Source References: PMID:32699809, PMID:33440146, PMID:33677541, PMID:34865044, PMID:37531250, PMID:38664429
Synonyms: ieSi57 II; ieSi58 IV.
Alternate IDs: WB-STRAIN:CA1202, CGC_CA1202
Notes: ieSi57 [eft-3p::TIR1::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II. ieSi58 [eft-3p::degron::GFP::unc-54 3'UTR + Cbr-unc-119(+)] IV. ieSi57 is a single copy transgene inserted into chromosome II (oxTi179) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in the soma. ieSi58 is a single copy transgene inserted into chromosome IV (oxTi177) expressing degron::GFP in the soma. This strain can be used as control for auxin-inducible degradation (AID) in somatic tissues. Reference: Zhang L, et al. Development. 2015 Nov 9. pii: dev.129635.|"WBStrain mapped, WBPaper00061130 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00004056 Copy
http://www.wormbase.org/db/get?name=WBStrain00004053
Source Database: WormBase (WB)
Affected Genes: WBGene00008580(dsb-1)
Genomic Alteration: WBGene00008580(dsb-1)
Availability: available
Source References: PMID:36176234
Synonyms: dsb-1(we11) IV/nT1[unc-?(n754) let-?] (IV;V).
Alternate IDs: WB-STRAIN:CA1117, CGC_CA1117
Notes: Heterozygotes are Unc and segregate Uncs, dead eggs, and non-Uncs (dsb-1 homozygotes), which produce 99% inviable embryos due to meiotic nondisjunction. Pick Unc to maintain and check for correct segregation of progeny. we11 is a TCA to TAA nonsense mutation in the dsb-1 coding sequence that introduces a premature stop after leucine 96. Reference: Stamper EL, et al. PLoS Genet. 2013;9(8):e1003679.|"Supplementary_genotype dsb-1(we11)/nT1g"
Proper citation: RRID:WB-STRAIN:WBStrain00004053 Copy
http://www.wormbase.org/db/get?name=WBStrain00004051
Source Database: WormBase (WB)
Availability: available
Synonyms: ieSi1 II; ltIs37 IV.
Alternate IDs: WB-STRAIN:CA756, CGC_CA756
Notes: ieSi1 [htp-3p::GFP::him-8 + unc-119(+)] II. ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. ieSi1 is prone to silencing; GFP might not be visible at lower magnifications. [NOTE: the ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV transgene was previously annotated as itIs37 in this strain. The correct name of the transgene is ltIs37 and not itIs37.] Reference: Wynne DJ, et al. J Cell Biol. 2012 Jan 9;196(1):47-64.|"Made_by: Dave Wynne"
Proper citation: RRID:WB-STRAIN:WBStrain00004051 Copy
http://www.wormbase.org/db/get?name=WBStrain00004048
Source Database: WormBase (WB)
Affected Genes: WBGene00006761(unc-24)|WBGene00011601(zim-3)
Genomic Alteration: WBGene00006761(unc-24), WBGene00011601(zim-3)
Availability: available
Source References: PMID:33377003, PMID:33713117, PMID:34081106
Synonyms: unc-24(e138) zim-3(tm2303) IV.
Alternate IDs: WB-STRAIN:CA448, CGC_CA448
Notes: Mutagen:UV/TMP|"Unc. Weak Him. Produces unhatched eggs."|"WBStrain mapped, WBPaper00060819 added based on AFP_Strain data."|"WBStrain mapped, WBPaper00061461 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00004048 Copy
http://www.wormbase.org/db/get?name=WBStrain00004046
Source Database: WormBase (WB)
Affected Genes: WBGene00011597(zim-1)
Genomic Alteration: WBGene00011597(zim-1)
Availability: available
Source References: PMID:36716349
Synonyms: zim-1(tm1813) IV.
Alternate IDs: WB-STRAIN:CA324, CGC_CA324
Notes: Mutagen:UV/TMP|"Weak Him. Produces unhatched eggs."
Proper citation: RRID:WB-STRAIN:WBStrain00004046 Copy
http://www.wormbase.org/db/get?name=WBStrain00004047
Source Database: WormBase (WB)
Affected Genes: WBGene00008641(pch-2)
Genomic Alteration: WBGene00008641(pch-2)
Availability: available
Source References: PMID:39237708
Synonyms: pch-2(tm1458) II.
Alternate IDs: WB-STRAIN:CA388, CGC_CA388
Notes: Defective for meiotic synapsis checkpoint. Recessive.
Proper citation: RRID:WB-STRAIN:WBStrain00004047 Copy
http://www.wormbase.org/db/get?name=WBStrain00004067
Source Database: WormBase (WB)
Affected Genes: WBGene00000962(dhc-1)
Genomic Alteration: WBGene00000962(dhc-1)
Availability: available
Synonyms: dhc-1(ie28[dhc-1::degron::GFP]) I; ieSi38 IV.
Alternate IDs: WB-STRAIN:CA1215, CGC_CA1215
Notes: ieSi38 [sun-1p::TIR1::mRuby::sun-1 3'UTR + Cbr-unc-119(+)] IV. Single copy transgene inserted into chromosome IV (cxTi10882) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in germ line and early embryos. A degron::GFP tag was inserted at the 3' end of the endogenous dhc-1 coding sequence via CRISPR/Cas9. This strain can be used to examine spatial and temporal requirements for dynein in the germ line and early embryos, and to serve as a control strain for auxin-inducible degradation (AID). Reference: Zhang L, et al. Development. 2015 Nov 9. pii: dev.129635.
Proper citation: RRID:WB-STRAIN:WBStrain00004067 Copy
http://www.wormbase.org/db/get?name=WBStrain00004100
Source Database: WormBase (WB)
Affected Genes: WBGene00006750(unc-10)
Genomic Alteration: WBGene00006750(unc-10)
Availability: available
Source References: PMID:4366476
Synonyms: unc-10(e102) X.
Alternate IDs: WB-STRAIN:CB102, CGC_CB102
Notes: Unc. Weak coiler.
Proper citation: RRID:WB-STRAIN:WBStrain00004100 Copy
http://www.wormbase.org/db/get?name=WBStrain00004065
Source Database: WormBase (WB)
Affected Genes: WBGene00000962(dhc-1)
Genomic Alteration: WBGene00000962(dhc-1)
Availability: available
Synonyms: dhc-1(ie28[dhc-1::degron::GFP]) I; ieSi60 II.
Alternate IDs: WB-STRAIN:CA1212, CGC_CA1212
Notes: ieSi60 [myo-2p::TIR1::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II. Single copy transgene inserted into chromosome II (oxTi179) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in pharyngeal muscle. A degron::GFP tag was inserted at the 3' end of the endogenous dhc-1 coding sequence via CRISPR/Cas9. This strain can be used to examine spatial and temporal requirements for dynein in pharyngeal muscle, and to serve as a control strain for auxin-inducible degradation (AID). Reference: Zhang L, et al. Development. 2015 Nov 9. pii: dev.129635.
Proper citation: RRID:WB-STRAIN:WBStrain00004065 Copy
http://www.wormbase.org/db/get?name=WBStrain00004063
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:37507441
Synonyms: ieSi61 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:CA1209, CGC_CA1209
Notes: ieSi61 [ges-1p::TIR1::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II. Single copy transgene inserted into chromosome II (oxTi179) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in the intestine. This strain can be used for auxin-inducible degradation (AID) in the intestine. Reference: Zhang L, et al. Development. 2015 Nov 9. pii: dev.129635.
Proper citation: RRID:WB-STRAIN:WBStrain00004063 Copy
http://www.wormbase.org/db/get?name=WBStrain00004057
Source Database: WormBase (WB)
Availability: available
Synonyms: ieEx21.
Alternate IDs: WB-STRAIN:CA1203, CGC_CA1203
Notes: ieEx21 [smu-2p::degron::smu-2::GFP::smu-2 3'UTR + rol-6(su1006)]. Rollers. Pick Rollers to maintain array. Rollers carry a transgene expressing degron- and GFP- tagged SMU-2 in both the soma and the germ line. This strain can be combined with different TIR1 strains to test auxin-inducible degradation (AID) of nuclear protein in various tissues. Reference: Zhang L, et al. Development. 2015 Nov 9. pii: dev.129635.
Proper citation: RRID:WB-STRAIN:WBStrain00004057 Copy
http://www.wormbase.org/db/get?name=WBStrain00004077
Source Database: WormBase (WB)
Affected Genes: WBGene00001071(dpy-9)
Genomic Alteration: WBGene00001071(dpy-9)
Availability: available
Source References: PMID:4366476
Synonyms: dpy-9(e12) IV.
Alternate IDs: WB-STRAIN:CB12, CGC_CB12
Notes: Dpy.
Proper citation: RRID:WB-STRAIN:WBStrain00004077 Copy
http://www.wormbase.org/db/get?name=WBStrain00004076
Source Database: WormBase (WB)
Affected Genes: WBGene00006747(unc-7)
Genomic Alteration: WBGene00006747(unc-7)
Availability: available
Source References: PMID:4366476, PMID:37103980, PMID:38302462
Synonyms: unc-7(e5) X.
Alternate IDs: WB-STRAIN:CB5, CGC_CB5
Notes: Unc. Moves backward better than forward, kinker in forward movement.
Proper citation: RRID:WB-STRAIN:WBStrain00004076 Copy
http://www.wormbase.org/db/get?name=WBStrain00004073
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:37708895
Synonyms: ieSi68 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:CA1472, CGC_CA1472
Notes: ieSi68 [sun-1p::TIR1::mRuby::htp-1 3'UTR + Cbr-unc-119(+)] II. Single copy transgene inserted into chromosome II (oxTi179) expressing a modified Arabidopsis thaliana TIR1 tagged with mRuby in the germ line and early embryos. This strain can be used for auxin-inducible degradation (AID) in germ line and early embryos. Reference: Zhang L, et al. Development. 2015 Nov 9. pii: dev.129635.|"Supplementary_genotype ieSi68[sun-1p::TIR1::mRuby::htp-1 3'UTR + Cbr-unc-119(+)] II; unc-119(ed3) III"
Proper citation: RRID:WB-STRAIN:WBStrain00004073 Copy
http://www.wormbase.org/db/get?name=WBStrain00004074
Source Database: WormBase (WB)
Affected Genes: WBGene00001063(dpy-1)
Genomic Alteration: WBGene00001063(dpy-1)
Availability: available
Source References: PMID:4366476, PMID:38877225, PMID:39420966
Synonyms: dpy-1(e1) III.
Alternate IDs: WB-STRAIN:CB1, CGC_CB1
Notes: Dpy.
Proper citation: RRID:WB-STRAIN:WBStrain00004074 Copy
http://www.wormbase.org/db/get?name=WBStrain00004072
Source Database: WormBase (WB)
Affected Genes: WBGene00006311(sun-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00006311(sun-1), WBGene00006843(unc-119)
Availability: available
Source References: PMID:37436986
Synonyms: ieSi65 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:CA1353, CGC_CA1353
Notes: ieSi65 [sun-1p::TIR1::sun-1 3UTR + Cbr-unc-119(+)] II. Single copy transgene inserted into chromosome II (oxTi179) expressing a modified Arabidopsis thaliana TIR1 in germ line and early embryos. This strain can be used for auxin-inducible degradation (AID) in germ line and early embryos. Reference: Zhang L, et al. Development. 2015 Nov 9. pii: dev.129635.
Proper citation: RRID:WB-STRAIN:WBStrain00004072 Copy
http://www.wormbase.org/db/get?name=WBStrain00004068
Source Database: WormBase (WB)
Affected Genes: WBGene00006377(syp-3)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00006377(syp-3), WBGene00006843(unc-119)
Availability: available
Synonyms: syp-3(ok758) I; ieSi11 II; unc-119(ed3) III.
Alternate IDs: WB-STRAIN:CA1218, CGC_CA1218
Notes: ieSi11 [syp-3p::EmeraldGFP::syp-3::syp-3 3'UTR + Cbr-unc-119(+)] II. ieSi11 was inserted into ttTi5605 II using MosSCI. Expression of GFP::SYP-3 largely complements syp-3(ok758), but some meiotic nondisjunction is detected above the N2 background (85% embryonic viability; ~1% male self-progeny;). GFP::SYP-3 expression is readily detected in spermatocytes and oocytes in the germline, and localizes to the interface between paired homologous chromosomes during most of meiotic prophase. Reference: Rog O, Dernburg AF. Cell Rep. 2015 Mar 10. pii: S2211-1247(15)00178-3.
Proper citation: RRID:WB-STRAIN:WBStrain00004068 Copy
http://www.wormbase.org/db/get?name=WBStrain00004088
Source Database: WormBase (WB)
Affected Genes: WBGene00006753(unc-14)
Genomic Alteration: WBGene00006753(unc-14)
Availability: available
Source References: PMID:4366476
Synonyms: unc-14(e57) I.
Alternate IDs: WB-STRAIN:CB57, CGC_CB57
Notes: Unc.
Proper citation: RRID:WB-STRAIN:WBStrain00004088 Copy
http://www.wormbase.org/db/get?name=WBStrain00004086
Source Database: WormBase (WB)
Affected Genes: WBGene00006752(unc-13)|WBGene00006845(unc-122)
Genomic Alteration: WBGene00006752(unc-13), WBGene00006845(unc-122)
Availability: available
Source References: PMID:4366476, PMID:38302462
Synonyms: unc-13(e51) unc-122(n2916) I.
Alternate IDs: WB-STRAIN:CB51, CGC_CB51
Notes: Unc. See WBPaper00003781 regarding the unc-122 mutation.
Proper citation: RRID:WB-STRAIN:WBStrain00004086 Copy
http://www.wormbase.org/db/get?name=WBStrain00004082
Source Database: WormBase (WB)
Affected Genes: WBGene00001065(dpy-3)
Genomic Alteration: WBGene00001065(dpy-3)
Availability: available
Source References: PMID:4366476
Synonyms: dpy-3(e27)
Alternate IDs: WB-STRAIN:CB27, CGC_CB27
Notes: Dpy. Recessive. M-MATING+POOR <1%WT.
Proper citation: RRID:WB-STRAIN:WBStrain00004082 Copy
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