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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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SS-Nlrp10em3Mcwi Resource Report Resource Website |
RRID:RGD_13207503 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Nlrp10 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 10-bp deletion of exon 2 in the Nlrp10 gene. Contact MCW rat distribution at [email protected] | 13207503 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13207503 | RGD | 2026-10-10 01:05:01 | 0 | |||||
|
SD-Rag1em1Sage Resource Report Resource Website |
RRID:RGD_12904900 | Rattus norvegicus | This ZFN model carries a 29 bp deletion within exon 2 of the Rag1 gene on chromosome 3. Homozygous animals display loss of Rag1 protein and loss of B and T cells by FACS analysis. Horizon Discovery | 12904900 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2017-05-24) | 12904900 | RGD | 2026-10-10 01:05:00 | 0 | |||||
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SD-Abcb11em1Sage Resource Report Resource Website |
RRID:RGD_12904730 | Rattus norvegicus | This ZFN induced knockout model contains biallelic 8-bp deletion within Abcb11 gene. The homozygous knockout rats display total loss of protein via Western blot. Horizon Discovery | 12904730 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-19) | 12904730 | RGD | 2026-10-10 01:05:01 | 0 | |||||
|
SD-Thtm1(cre)Sage Resource Report Resource Website 1+ mentions |
RRID:RGD_12905029 | Rattus norvegicus | This ZFN knock in model expresses cre-recombinase under the control of the endogenous tyrosine hydroxylase promoter enabling specific expression in dopaminergic neurons. This model possesses a targeted insertion of (IRES)-cre immediately after the translational stop in the open reading frame of Th. The TH-Cre rat is useful for applications requiring tissue specific expression, including optogenetics and breeding with transgenic floxed lines. Horizon Discovery | 12905029 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-31) | 12905029 | RGD | 2026-10-10 01:05:01 | 3 | |||||
|
SS-Nox4em2Ncf2em1Mcwi Resource Report Resource Website |
RRID:RGD_13506176 | Rattus norvegicus | Breeding together of SS-Nox4em2Mcwi (RGDID: 4139883) and SS-Ncf2em1Mcwi (RGDID: 5144104), both models were generated by ZFN mutagenesis. Contact MCW rat distribution at [email protected] | 13506176 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm; Cryorecovery (as of 2018-11-12) | 13506176 | RGD | 2026-10-10 01:05:01 | 0 | |||||
|
FHH-Chr 1BN-Dusp5em1Mcwi Resource Report Resource Website |
RRID:RGD_13451538 | Rattus norvegicus | This strain was produced by injecting ZFNs targeting the following sequence CAGGGCAGCCGC-CACtggcaGAAGCTGCGGGAGGA in exon 1 of the rat Dusp5 gene into FHH-Chr 1BN/Mcwi embryos. The resulting mutation is a 14 bp deletion and a 3 bp insertion between nucleotides 449 and 464 in Dusp5 mRNA that creates a frame shift mutation which is predicted to introduce a premature stop codon at amino acid 121. | 13451538 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13451538 | RGD | 2026-10-10 01:05:01 | 0 | |||||
|
SS-Spp1em3Mcwi Resource Report Resource Website |
RRID:RGD_13207525 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Spp1 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 4-bp deletion in Exon 3 of the Spp1 gene. Contact MCW rat distribution at [email protected] | 13207525 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13207525 | RGD | 2026-10-10 01:05:01 | 0 | |||||
|
SS-Ptgs2em2Mcwi Resource Report Resource Website |
RRID:RGD_13208844 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Ptgs2 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 7-bp deletion of exon 4 in the Ptgs2 gene. Contact MCW rat distribution at [email protected] | 13208844 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13208844 | RGD | 2026-10-10 01:05:01 | 0 | |||||
|
SD-Rag2em3McwiIl2rgem2Mcwi Resource Report Resource Website |
RRID:RGD_13207516 | Rattus norvegicus | This strain was produced by crossing of SD-Rag2em3Mcwi and SD-Il2rgem2Mcwi. Contact MCW rat distribution at [email protected] | 13207516 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13207516 | RGD | 2026-10-10 01:05:00 | 0 | |||||
|
SD-Lepem1Sage-/- Resource Report Resource Website |
RRID:RGD_12904912 | Rattus norvegicus | This ZFN model possesses a 151 bp deletion spanning exon 1/intron 1 junction of Leptin gene. Homozygous knockout rats display loss of Leptin protein via Western blot. Homozygous knockout rats demonstrate significant weight gain compared to wild type littermates. Homozygous knockout rats show significantly elevated serum cholesterol levels Inotiv | 12904912 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2017-05-24) | 12904912 | RGD | 2026-10-10 01:05:01 | 0 | |||||
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SS-P2rx7em13Mcwi Resource Report Resource Website |
RRID:RGD_13506832 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the P2rx7 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is an 10-bp putative frame-shift deletion in exon 2 Contact MCW rat distribution at [email protected] | 13506832 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13506832 | RGD | 2026-10-10 01:05:01 | 0 | |||||
|
SS-P2rx7em10Mcwi Resource Report Resource Website |
RRID:RGD_13506831 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the P2rx7 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is an 11-bp putative frame-shift deletion in exon 2 Contact MCW rat distribution at [email protected] | 13506831 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-02-21) | 13506831 | RGD | 2026-10-10 01:05:01 | 0 | |||||
|
SD-Slc22a2em1Sage Resource Report Resource Website |
RRID:RGD_12904891 | Rattus norvegicus | This ZFN model carries the knockout of the rat Slc22a2. Horizon Discovery | 12904891 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-24) | 12904891 | RGD | 2026-10-10 01:05:01 | 0 | |||||
|
SD-Slc22a6em1Sage Resource Report Resource Website |
RRID:RGD_12904892 | Rattus norvegicus | This ZFN model carries the knockout of the rat Slc22a6. Horizon Discovery | 12904892 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2017-05-24) | 12904892 | RGD | 2026-10-10 01:05:01 | 0 | |||||
|
SD-Tp53em1Sage Resource Report Resource Website |
RRID:RGD_12904897 | Rattus norvegicus | This ZFN model carries the monoallelic 11 base pair deletion in Tp53 gene. Animals exhibit broad tumor spectrum with high degree of tumor malignancy. Horizon Discovery | 12904897 | mutant | Rat Genome Database (RGD) | RGD | Extinct (as of 2024-04-16) | 12904897 | RGD | 2026-10-10 01:05:01 | 0 | |||||
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SD-Lepem1 Resource Report Resource Website |
RRID:RGD_13210578 | Rattus norvegicus | This CRISPR/Cas9 model possesses a 3 bp(ATC) deletion resulting in the deletion of isoleucine at position 14. The Lep mutant rats exhibited similar mutant phenotypes to Lep and Lepr null rats. | 13210578 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13210578 | RGD | 2026-10-10 01:05:02 | 0 | |||||
|
FHH-Mybphlem2Mcwi Resource Report Resource Website |
RRID:RGD_13800845 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 1 of rat Mybphl gene in the FHH/EurMcwi embryos. embryos. Contact MCW rat distribution at [email protected] | 13800845 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2023-06-21) | 13800845 | RGD | 2026-10-10 01:05:02 | 0 | |||||
|
SS-P2rx7em12Mcwi Resource Report Resource Website |
RRID:RGD_13792803 | Rattus norvegicus | This allele was made by CRISPR/Cas9 system. The resulting mutation is a 10-bp deletion in Exon 2 of the P2rx7 gene. | 13792803 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2023-06-21) | 13792803 | RGD | 2026-10-10 01:05:03 | 0 | |||||
|
SS-Nlrp3em2Mcwi Resource Report Resource Website |
RRID:RGD_13792801 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Nlrp3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 14-bp deletion of exon 1 in the Nlrp3 gene. Contact MCW rat distribution at [email protected] | 13792801 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-09-28) | 13792801 | RGD | 2026-10-10 01:05:03 | 0 | |||||
|
SD-Ldlrem1 Resource Report Resource Website |
RRID:RGD_12910101 | Rattus norvegicus | This model possesses a 19-bp deletion in the seventh exon of the ldlr gene by ZFN method. | 12910101 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 12910101 | RGD | 2026-10-10 01:05:02 | 0 |
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