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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00003971
Source Database: WormBase (WB)
Affected Genes: WBGene00000904(daf-8)|WBGene00006773(unc-37)
Genomic Alteration: WBGene00000904(daf-8), WBGene00006773(unc-37)
Availability: available
Synonyms: unc-37(e262) daf-8(e1393) I.
Alternate IDs: WB-STRAIN:BW1046, CGC_BW1046
Notes: Unc. Constitutive dauer formation (Daf-c) at 25C.
Proper citation: RRID:WB-STRAIN:WBStrain00003971 Copy
http://www.wormbase.org/db/get?name=WBStrain00003972
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00006776(unc-40)
Genomic Alteration: WBGene00000254(bli-4), WBGene00006776(unc-40)
Availability: available
Synonyms: unc-40(e271) bli-4(e937) I.
Alternate IDs: WB-STRAIN:BW1049, CGC_BW1049
Notes: UncBli Strain. Blisters late.
Proper citation: RRID:WB-STRAIN:WBStrain00003972 Copy
http://www.wormbase.org/db/get?name=WBStrain00003990
Source Database: WormBase (WB)
Affected Genes: WBGene00001078(dpy-19)|WBGene00001609(glp-1)|WBGene00003912(pal-1)
Genomic Alteration: WBGene00001078(dpy-19), WBGene00001609(glp-1), WBGene00003912(pal-1)
Availability: available
Synonyms: pal-1(ct281)/qC1 [dpy-19(e1259) glp-1(q339)] III.
Alternate IDs: WB-STRAIN:BW1563, CGC_BW1563
Notes: Heterozygotes are WT and segregate WT, DpySteriles and dead eggs. Pick wild-type heterozygotes to maintain. ct281 homozygotes show Nob phenotype: approximately 80% of homozygous embryos arrest at about the time of hatching with fairly normal anterior development but a severely deformed posterior with a variable knob-like shape; approximately 20% fail to enclose and do not hatch. ct281 is a 4.7kb deletion removing intron 5, exon 6, and the 3'UTR of the pal-1 gene. Reference: Edgar LG, et al. Dev Biol. 2001 Jan 1;229(1):71-88.
Proper citation: RRID:WB-STRAIN:WBStrain00003990 Copy
http://www.wormbase.org/db/get?name=WBStrain00003908
Source Database: WormBase (WB)
Affected Genes: WBGene00001332(eri-1)|WBGene00023497(lin-15B)
Genomic Alteration: WBGene00001332(eri-1), WBGene00023497(lin-15B)
Availability: unknown
Source References: PMID:22611162
Synonyms: eri-1(mg366) IV; lin-15B(n744) X; byIs161; bkIs10.
Alternate IDs: WB-STRAIN:BR5625
Notes: eri-1(mg366)IV;lin-15B(n744)X;byIs161;bkIs10 (pro-aggregant, neuronal RNAi-sensitized strain),
Proper citation: RRID:WB-STRAIN:WBStrain00003908 Copy
http://www.wormbase.org/db/get?name=WBStrain00003909
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:22611162
Synonyms: byIs162; bkIs10; juIs73.
Alternate IDs: WB-STRAIN:BR5674
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00003909 Copy
http://www.wormbase.org/db/get?name=WBStrain00003906
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:22611162
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:BR5578
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00003906 Copy
http://www.wormbase.org/db/get?name=WBStrain00003907
Source Database: WormBase (WB)
Affected Genes: WBGene00006526(tax-4)
Genomic Alteration: WBGene00006526(tax-4)
Availability: available
Synonyms: tax-4(p678) III; byEx836.
Alternate IDs: WB-STRAIN:BR5602, CGC_BR5602
Notes: byEx836 [odr-4p::tax-4::GFP + myo-2p::mCherry]. Pick mCherry+ animals to maintain. Rescues tax-4 null mutant. Expresses tax-4(+) in AWA, AWB, AWC, ADF, ASG, ASH, ASI, ASJ, ASK, ADL, PHA, and PHB sensory neurons, but not AFD sensory neurons. Reference: Liu S, Schulze E, Baumeister R. PLoS One. 2012;7(3):e32360.
Proper citation: RRID:WB-STRAIN:WBStrain00003907 Copy
http://www.wormbase.org/db/get?name=WBStrain00003904
Source Database: WormBase (WB)
Availability: available
Synonyms: byIs162; bkIs10.
Alternate IDs: WB-STRAIN:BR5486, CGC_BR5486
Notes: byIs162 [rab-3p::F3(delta)K280(I277P)(I308P) + myo-2p::mCherry]. bkIs10 [aex-3p::h4R1NtauV337M + myo-2p::GFP]. Strain co-expressing the F3(delta)K280 anti-aggregation Tau fragment (with two I to P substitutions) and full-length Tau in all neurons. Red and green fluorescence in the pharynx due to the co-injection markers. The F3/2P fragment is not able to nucleate aggregation of full length Tau. bkIs10 contains an integrated transgene encoding the 1N4R isoforms of human tau with the 337M FTDP-17 mutation. Expression is driven by the pan-neuronal promoter aex-3. Over-expression of this transgene results in a pronounced Unc phenotype. Reference: Fatouros C, et al. Hum Mol Genet. 2012 Aug 15;21(16):3587-603.
Proper citation: RRID:WB-STRAIN:WBStrain00003904 Copy
http://www.wormbase.org/db/get?name=WBStrain00003905
Source Database: WormBase (WB)
Affected Genes: WBGene00006525(tax-2)|WBGene00006526(tax-4)
Genomic Alteration: WBGene00006525(tax-2), WBGene00006526(tax-4)
Availability: available
Synonyms: tax-2(p671) I; tax-4(p678) III.
Alternate IDs: WB-STRAIN:BR5514, CGC_BR5514
Notes: Reference: Liu S, Schulze E, Baumeister R. PLoS One. 2012;7(3):e32360.
Proper citation: RRID:WB-STRAIN:WBStrain00003905 Copy
http://www.wormbase.org/db/get?name=WBStrain00003902
Source Database: WormBase (WB)
Availability: available
Source References: PMID:37549461, PMID:39149885
Synonyms: byIs162.
Alternate IDs: WB-STRAIN:BR5271, CGC_BR5271
Notes: byIs162 [rab-3p::F3(delta)K280 I277P I380P + myo-2p::mCherry]. Pan-neuronal over-expression of the F3 pro aggregation fragment of the human Tau protein with K280 deleted and two isoleucines to proline substitutions in the hexapeptide motifs of the repeat region (line A). These mutations abrogate the aggregation, making this strain an anti-aggregation control for BR5270. Reference: Fatuouros C, et al. Hum Mol Genet. 2012 Aug 15;21(16):3587-603.|"byIs162 [rab-3p::F3(delta)K280 I277P I380P + myo-2p::mCherry]. Pan-neuronal overexpression of the F3 pro aggregation fragment of the human Tau protein with K280 deleted and two isoleucines to proline substitutions in the hexapeptide motifs of the repeat region (line A). These mutations abrogate the aggregation, making this strain an anti-aggregation control for BR5270. Reference: Fatuouros C, et al. Hum Mol Genet. 2012 Aug 15;21(16):3587-603."|"Made_by: C. Fatouros"|"Mutagen:Gamma radiation"
Proper citation: RRID:WB-STRAIN:WBStrain00003902 Copy
http://www.wormbase.org/db/get?name=WBStrain00003988
Source Database: WormBase (WB)
Affected Genes: WBGene00001077(dpy-18)|WBGene00001078(dpy-19)|WBGene00001609(glp-1)|WBGene00006762(unc-25)
Genomic Alteration: WBGene00001077(dpy-18), WBGene00001078(dpy-19), WBGene00001609(glp-1), WBGene00006762(unc-25)
Availability: available
Synonyms: dpy-18(e364) ctDf3 unc-25(e156)/qC1 [dpy-19(e1259) glp-1(q339)] III.
Alternate IDs: WB-STRAIN:BW1535, CGC_BW1535
Notes: Heterozygotes are WT and segregate WT, DpySteriles and dead eggs. Maintain by picking WT.|"Made_by: Nurit Wolf"|"Mutagen: Trimethylpsoalen"
Proper citation: RRID:WB-STRAIN:WBStrain00003988 Copy
http://www.wormbase.org/db/get?name=WBStrain00003989
Source Database: WormBase (WB)
Affected Genes: WBGene00001077(dpy-18)|WBGene00003779(nob-1)|WBGene00006762(unc-25)
Genomic Alteration: WBGene00001077(dpy-18), WBGene00003779(nob-1), WBGene00006762(unc-25)
Availability: available
Synonyms: dpy-18(e364) nob-1(ct223) unc-25(e156) III; eDp6 (III;f).
Alternate IDs: WB-STRAIN:BW1561, CGC_BW1561
Notes: Animals with the duplication are WT. Animals without the duplication are Nob (NO Back end; 100% lethal). Pick wild-type to maintain. The Dpy and Unc phenotypes are not visible in the Nob background. ct223 is recessive.|"Mutagen: Trimethylpsoalen"
Proper citation: RRID:WB-STRAIN:WBStrain00003989 Copy
http://www.wormbase.org/db/get?name=WBStrain00003987
Source Database: WormBase (WB)
Affected Genes: WBGene00001076(dpy-17)|WBGene00001842(her-1)|WBGene00001867(him-8)|WBGene00006778(unc-42)
Genomic Alteration: WBGene00001076(dpy-17), WBGene00001842(her-1), WBGene00001867(him-8), WBGene00006778(unc-42)
Availability: available
Source References: PMID:1741033
Synonyms: dpy-17(e164) III; him-8(e1489) IV; her-1(y101hv1) unc-42(e270) V; ctDp11 (III;V;f).
Alternate IDs: WB-STRAIN:BW1434, CGC_BW1434
Notes: Mutagen:Gamma Rays|"Wild type hermaphrodites and males which produce WT, Dpy, Unc and DpyUnc progeny due to mating or loss of the duplication. Pick WT hermaphrodites and males to maintain."
Proper citation: RRID:WB-STRAIN:WBStrain00003987 Copy
http://www.wormbase.org/db/get?name=WBStrain00003985
Source Database: WormBase (WB)
Affected Genes: WBGene00003779(nob-1)
Genomic Alteration: WBGene00003779(nob-1)
Availability: available
Synonyms: nob-1(ct223) III; eDp6 (III;f).
Alternate IDs: WB-STRAIN:BW1341, CGC_BW1341
Notes: Animals with the duplication are WT. Animals without the duplication are Nob (NO Back end; 100% lethal). Pick wild-type to maintain; typically segregates about 50% wild type progeny and 50% Nob larvae.|"Mutagen: Trimethylpsoalen"
Proper citation: RRID:WB-STRAIN:WBStrain00003985 Copy
http://www.wormbase.org/db/get?name=WBStrain00003983
Source Database: WormBase (WB)
Affected Genes: WBGene00006759(unc-22)
Genomic Alteration: WBGene00006759(unc-22)
Availability: available
Source References: PMID:7906415
Synonyms: unc-22(ct181) IV.
Alternate IDs: WB-STRAIN:BW1176, CGC_BW1176
Notes: Made_by Mark Yandell|"Made_by: Mark Yandell"|"Mutagen: Trimethylpsoalen"
Proper citation: RRID:WB-STRAIN:WBStrain00003983 Copy
http://www.wormbase.org/db/get?name=WBStrain00003980
Source Database: WormBase (WB)
Affected Genes: WBGene00006759(unc-22)
Genomic Alteration: WBGene00006759(unc-22)
Availability: available
Source References: PMID:7906415
Synonyms: unc-22(ct174) IV.
Alternate IDs: WB-STRAIN:BW1166, CGC_BW1166
Notes: Mutagen: Trimethylpsoalen|"Twitcher."
Proper citation: RRID:WB-STRAIN:WBStrain00003980 Copy
http://www.wormbase.org/db/get?name=WBStrain00003981
Source Database: WormBase (WB)
Affected Genes: WBGene00006759(unc-22)
Genomic Alteration: WBGene00006759(unc-22)
Availability: available
Source References: PMID:7906415
Synonyms: unc-22(ct176) IV.
Alternate IDs: WB-STRAIN:BW1168, CGC_BW1168
Notes: Mutagen: Trimethylpsoalen|"Twitcher."
Proper citation: RRID:WB-STRAIN:WBStrain00003981 Copy
http://www.wormbase.org/db/get?name=WBStrain00003918
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:22611162
Synonyms: byIs162; bkIs10; wyEx2709.
Alternate IDs: WB-STRAIN:BR6012
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00003918 Copy
http://www.wormbase.org/db/get?name=WBStrain00003915
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:22611162
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:BR5960
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00003915 Copy
http://www.wormbase.org/db/get?name=WBStrain00003914
Source Database: WormBase (WB)
Availability: available
Synonyms: byIs193.
Alternate IDs: WB-STRAIN:BR5944, CGC_BR5944
Notes: byIs193 [rab-3p::F3(delta)K280 + myo-2p::mCherry]. F3 pro aggregation fragment is expressed at low levels (line B); hard to detect by western blot. Reference: Fatuouros C, et al. Hum Mol Genet. 2012 Aug 15;21(16):3587-603.|"Made_by: C. Fatouros"|"Mutagen:Gamma radiation"
Proper citation: RRID:WB-STRAIN:WBStrain00003914 Copy
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