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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=7228
Source Database: Australian Phenome Bank
Affected Genes: tumor necrosis factor|RB transcriptional corepressor 1
Genomic Alteration: targeted mutation 1; George Kollias|targeted mutation 3; Tyler Jacks
Availability: sperm
Synonyms: B6.Cg-Rb1
Notes: gene symbol note: tumor necrosis factor|RB transcriptional corepressor 1; mutant strain: Tnf|Rb1
Proper citation: RRID:IMSR_APB:7228 Copy
Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=7468
Source Database: Australian Phenome Bank
Affected Genes: Fas cell surface death receptor||histocompatibility-2; MHC|recombination activating 1
Genomic Alteration: lymphoproliferation|transgene insertion 10395; Bernd Arnold|k variant|targeted mutation 1; Peter Mombaerts
Availability: sperm
Synonyms: B10.Cg-H2
Notes: gene symbol note: Fas cell surface death receptor||histocompatibility-2; MHC|recombination activating 1; mutant strain|congenic strain: Fas||H2|Rag1
Proper citation: RRID:IMSR_APB:7468 Copy
Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=7544
Source Database: Australian Phenome Bank
Affected Genes: toll-like receptor 2
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: sperm
Synonyms: B6.129P2-Tlr2
Notes: gene symbol note: toll-like receptor 2; mutant strain: Tlr2
Proper citation: RRID:IMSR_APB:7544 Copy
Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=7793
Source Database: Australian Phenome Bank
Affected Genes: lamin A
Genomic Alteration: targeted mutation 1; Colin L Stewart
Availability: sperm
Notes: gene symbol note: lamin A; congenic strain: Lmna
Proper citation: RRID:IMSR_APB:7793 Copy
Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=8586
Source Database: Australian Phenome Bank
Affected Genes: |sphingosine kinase 2|sphingosine kinase 1
Genomic Alteration: transgene insertion 1; University of Cologne|targeted mutation 1; Richard L Proia|targeted mutation 2; Shaun R Coughlin
Availability: sperm
Notes: gene symbol note: |sphingosine kinase 2|sphingosine kinase 1; mutant strain: |Sphk2|Sphk1
Proper citation: RRID:IMSR_APB:8586 Copy
Issue
https://db.pb.apf.edu.au/phenbank/strain.html?id=8631
Source Database: Australian Phenome Bank
Affected Genes: apolipoprotein E|toll-like receptor 9
Genomic Alteration: targeted mutation 1; University of North Carolina|targeted mutation 1; Shizuo Akira
Availability: sperm
Notes: gene symbol note: apolipoprotein E|toll-like receptor 9; mutant strain: Apoe|Tlr9
Proper citation: RRID:IMSR_APB:8631 Copy
Issue Issue
https://archive.har.mrc.ac.uk/stock?id=2027
Source Database: MRC Harwell
Genomic Alteration: transgene insertion FM16; Peter Griffiths
Availability: embryo
Notes: gene symbol note: ; mutant stock:
Proper citation: RRID:IMSR_HAR:2027 Copy
Issue
https://archive.har.mrc.ac.uk/stock?id=239
Source Database: MRC Harwell
Affected Genes: paired box 3
Genomic Alteration: splotch 2 Harwell
Availability: embryo
Notes: gene symbol note: paired box 3; mutant strain: Pax3
Proper citation: RRID:IMSR_HAR:239 Copy
Issue
https://archive.har.mrc.ac.uk/stock?id=4189
Source Database: MRC Harwell
Affected Genes: forkhead box P3
Genomic Alteration: scurfy
Availability: embryo
Notes: gene symbol note: forkhead box P3; mutant stock: Foxp3
Proper citation: RRID:IMSR_HAR:4189 Copy
Issue
The record is no longer available at this source.
Source Database: National Cancer Institute at Frederick
Affected Genes: cyclin dependent kinase inhibitor 2A
Genomic Alteration: targeted mutation 1; Ronald DePinho
Availability: embryo
Notes: gene symbol note: cyclin dependent kinase inhibitor 2A; congenic strain: Cdkn2a
Proper citation: RRID:IMSR_NCIMR:01XB2 Copy
Issue
The record is no longer available at this source.
Source Database: National Cancer Institute at Frederick
Affected Genes: cyclin dependent kinase inhibitor 2A
Genomic Alteration: targeted mutation 1; Ronald DePinho
Availability: embryo
Notes: gene symbol note: cyclin dependent kinase inhibitor 2A; congenic strain: Cdkn2a
Proper citation: RRID:IMSR_NCIMR:01XB1 Copy
Issue
The record is no longer available at this source.
Source Database: National Cancer Institute at Frederick
Affected Genes: transgene insertion 4496; William A Weiss|cyclin dependent kinase inhibitor 2A
Genomic Alteration: transgene insertion 4496; William A Weiss|targeted mutation 1; Ronald DePinho
Availability: embryo
Notes: gene symbol note: transgene insertion 4496; William A Weiss|cyclin dependent kinase inhibitor 2A; congenic strain: Tg(S100b-v-erbB)4496Waw|Cdkn2a
Proper citation: RRID:IMSR_NCIMR:01XD3 Copy
Issue
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: toll-like receptor 9|toll-like receptor 2|toll-like receptor 4
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: embryo
Synonyms: TLR2/4/9 Triple KO C57BL/6. B6.129P2-Tlr2
Notes: gene symbol note: toll-like receptor 9|toll-like receptor 2|toll-like receptor 4; mutant strain|congenic strain: Tlr9|Tlr2|Tlr4
Proper citation: RRID:IMSR_OBS:21 Copy
Issue
https://orientalbioservice.com/index.files/tlr_eng.htm
Source Database: Oriental BioService, Inc.
Affected Genes: toll-like receptor 4|toll-like receptor 2
Genomic Alteration: targeted mutation 1; Shizuo Akira
Availability: embryo
Synonyms: B6.129P2-Tlr2
Notes: gene symbol note: toll-like receptor 4|toll-like receptor 2; mutant strain|congenic strain: Tlr4|Tlr2
Proper citation: RRID:IMSR_OBS:19 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=1
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: immunoglobulin heavy constant mu
Genomic Alteration: targeted mutation 1; University of Cologne
Availability: embryo
Synonyms: muMT<0>(muKO)
Alternate IDs: SCR_006136
Notes: gene symbol note: immunoglobulin heavy constant mu; mutant strain: Ighm
Proper citation: RRID:IMSR_EM:00001 Copy
Issue
https://www.infrafrontier.eu/emma/strain-details/?q=29
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: beta-2 microglobulin
Genomic Alteration: targeted mutation 1; University of North Carolina
Availability: archived
Synonyms: beta2m<0>
Alternate IDs: SCR_006136
Notes: gene symbol note: beta-2 microglobulin; mutant strain: B2m
Proper citation: RRID:IMSR_EM:00029 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=158
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: prion protein
Genomic Alteration: targeted mutation 1; Charles Weissmann
Availability: embryo
Synonyms: B6;129S7-Prnp
Alternate IDs: SCR_006136
Notes: gene symbol note: prion protein; mutant strain: Prnp
Proper citation: RRID:IMSR_EM:00158 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=181
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: transgene insertion a20; Charles Weissmann|prion protein
Genomic Alteration: transgene insertion a20; Charles Weissmann|targeted mutation 1; Charles Weissmann
Availability: embryo
Synonyms: Tga20. B6;129S7 Prnp
Alternate IDs: SCR_006136
Notes: gene symbol note: transgene insertion a20; Charles Weissmann|prion protein; mutant strain: Tg(Prnp)a20Cwe|Prnp
Proper citation: RRID:IMSR_EM:00181 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=180
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: transgene insertion a19; Charles Weissmann|prion protein
Genomic Alteration: transgene insertion a19; Charles Weissmann|targeted mutation 1; Charles Weissmann
Availability: embryo
Synonyms: PrPC-KO. Tga19. B6;129S7 Prnp
Alternate IDs: SCR_006136
Notes: gene symbol note: transgene insertion a19; Charles Weissmann|prion protein; mutant strain: Tg(Prnp)a19Cwe|Prnp
Proper citation: RRID:IMSR_EM:00180 Copy
Issue Issue
https://www.infrafrontier.eu/emma/strain-details/?q=178
Source Database: European Mouse Mutant Archive, European Mouse Mutant Archive - EMMA, European Mouse Mutant Archive (EMMA)
Affected Genes: transgene insertion 33; Charles Weissmann|prion protein
Genomic Alteration: transgene insertion 33; Charles Weissmann|targeted mutation 1; Charles Weissmann
Availability: embryo
Synonyms: PrPC-KO.Tg33. Tg33. B6;129S7-Prnp
Alternate IDs: SCR_006136
Notes: gene symbol note: transgene insertion 33; Charles Weissmann|prion protein; mutant strain: Tg(Lck-Prnp)33Cwe|Prnp
Proper citation: RRID:IMSR_EM:00178 Copy
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