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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2314361
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Sperm
Alternate IDs: 2314361
Notes: This transgenic rat was established at National Institute for Physiological Sciences in 2004, thereafter introduced to Gunma University in 2006. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2314361 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2314363
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Sperm
Alternate IDs: 2314363
Notes: This transgenic rat was established at National Institute for Physiological Sciences in 2004, thereafter introduced to Gunma University in 2006. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2314363 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2314247
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 2314247
Notes: A transgenic construct was designed with the rat prolactin promoter (-3221 - 3233) controlling EGFP. Transgenic rats originated from Crlj:WI (Wistar) rats National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2314247 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2304298
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 2304298
Notes: This strain expresses the enhanced yellow fluorescent protein (YGFP) neuron-specific driven by the Tubulin, alpha 1A promoter. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2304298 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2304331
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: 2304331
Notes: Deposited by the DEPOSITOR National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_2304331 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4140403
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 4140403
Notes: Background strain is Slc:SD. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4140403 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4140402
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 4140402
Notes: The construct which contains of rat growth hormone (Gh1) promoter, 4 copies of thyroid hormone response element (TRE), and antisense sequences for rat Gh1 cDNA was injected into Jcl:Wistar embryo (Matsumoto, 1993). This transgenic rat was established at NT Science in 1992, and transferred to Japan Bio Science Laboratory Co., Ltd. in 2003. This strain has been maintained at Nagasaki University Graduate School of Biomedical Science. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4140402 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4140416
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 4140416
Notes: This transgenic strain was generated by microinjection into Slc:SD fertilized eggs. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4140416 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=4140410
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 4140410
Notes: Background strain is Slc:SD. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_4140410 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=329955364
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 329955364
Notes: Transgene insertion (human CD68-GFP) using Sleeping Beauty transposon system on Wistar Kyoto rats. Rat monocyte/macrophage reporter strain on a WKY background which has susceptibility to experimental glomerulonephritis. GFP expression occurs exclusively within blood monocytes and tissue macrophages.
Proper citation: RRID:RGD_329955364 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=404976872
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2024-03-18)
Alternate IDs: 404976872
Notes: CD-Tg(RNECO-180E22)733Arno, RGD:155663367 was backcrossed at the Medical College of Wisconsin to DA/MolTacMcwi for 6-7 generations before cryopreservation of sperm. Contact MCW rat distribution at [email protected]
Proper citation: RRID:RGD_404976872 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598092606
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-03-28)
Alternate IDs: 598092606
Notes: This strain was established by a use of the BAC transgenic method with a technical support from the C.B.S.N resource (Dr. Kazuto Kobayashi, Fukushima Medical University, Dr. Yuchio Yanagawa, Gunma University Graduate School of Medicine). This transgenic rat was transported to The Jikei University School of Medicine, and cre recombinase expression was confirmed by crossing it with a reporter rat (NBRP Rat No: 0734). These rats are maintained in The Jikei University School of Medicine. Background strain: Crlj:WI.
Transgene: Dbh (dopamine beta-hydroxylase: rat), TetR (E.coli), VP16 protein minimal“F”-type activation domain (Herpes simplex virus), 2A (Thosea asigna virus), cre recombinase (P1 Phage), bGlobin polyA (rabbit), loxP (P1 phage). Detailed method (BAC transgenic method): a rat BAC clone was used (CH230-211J22). Combined mRNA for tTA and cre recombinase sequences is transcribed under the control of Dbh promoter. In translation step, the transcript is cut at the 2A peptide sequence, resulting in a separate protein production of tTA and Cre. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_598092606 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598154611
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 598154611
Notes: The full length humanTOR1A wild type gene including upstream and downstream flanking regions were inserted into a pUC19 vector. Following linearization and purification the transgenes were used to generate transgenic rats by microinjection of the DNA construct into the pronucleus of rat zygotes. Transgenic rats were kept on Sprague–Dawley background and bred as hemizygotes using standard procedures. Genotypes of offspring were determined by PCR and sequencing of DNA extracted from ear biopsies. Primer pair 5′-TAAAAATGTGTATCCGAGTGGAAAT (forward) and 5′-AAGGACTGAGTGTTGTTTCTTTTC (reverse) amplified a 230 bp segment within the coding sequence of exon 5 under the following conditions: 94 °C for 1 min, 60 °C for 1 min and 72 °C for 1 min, 40 cycles. Only lines that showed stable germline transmission of the transgenes were used for further analyses.
Proper citation: RRID:RGD_598154611 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598154612
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 598154612
Notes: The 16.25 kbps full length human DYT1 allele of TOR1A gene including upstream and downstream flanking regions were inserted into a pUC19 vector. Following linearization and purification the transgenes were used to generate transgenic rats by microinjection of the DNA construct into the pronucleus of rat zygotes. Transgenic rats were kept on Sprague–Dawley background and bred as hemizygotes using standard procedures. Genotypes of offspring were determined by PCR and sequencing of DNA extracted from ear biopsies. Primer pair 5′-TAAAAATGTGTATCCGAGTGGAAAT (forward) and 5′-AAGGACTGAGTGTTGTTTCTTTTC (reverse) amplified a 230 bp segment within the coding sequence of exon 5 under the following conditions: 94 °C for 1 min, 60 °C for 1 min and 72 °C for 1 min, 40 cycles. Only lines that showed stable germline transmission of the transgenes were used for further analyses.
Proper citation: RRID:RGD_598154612 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=598092579
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2025-03-27)
Alternate IDs: 598092579
Notes: Background strain: Long-Evans rat (Iar:Long-Evans). This strain was established by injection of modified BAC (cre gene was inserted into the exon 2 of rat Tac1 gene) into Long-Evans rat's fertiled eggs. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_598092579 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=405849385
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 405849385
Notes: The hDNMT3A transgenic rats were established using zygote microinjection of a bacterial artificial chromosome (BAC). The RP11-159D24 BAC (NCBI-ID:223335, Homo sapiens, GRCh38.p2: Chr. 2: 25,202,642-25,410,145, total length: 207,504 bp) containing DNMT3A (GRCh38.p2: 25,232,961,25,342,590, total length: 109,630 bp) was injected into rat zygotes (Rattus norvegicus, Sprague-Dawley, SD). The offspring were identified with 8 PCR primer-pairs that were specific for the RP11-159D24 sequence to detect positive transgenic ones.
Proper citation: RRID:RGD_405849385 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=632522750
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 632522750
Notes: This is the wild type littermate of the transgenic rat strain carrying human NR3C2 (RGD:632522749).
Proper citation: RRID:RGD_632522750 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=626168247
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 626168247
Notes: A chimeric AVP-hM3Dq-mCherry BAC clone transgene construct was
purified for microinjections. hM3Dq is a modified form of the human M3 muscarinic receptor (hM3; CHRM3*). It can be activated by the inert clozapine metabolite clozapine-N-oxide (CNO), engaging the Gq signaling pathway.The hM3Dq-mCherry sequence from the hM3Dq-mCherry cassette (Plasmid
#44361, Addgene, Cambridge, MA, USA) was used for the transgene. Next, SV40 poly A sequence was framed to the hM3Dq-mCherry sequence. Finally, this
hM3Dq-mCherry-SV40 poly A cassette was introduced into the rat Avp gene in place of the genomic start
codon. Thus, hM3Dq-mCherry should be specifically expressed under the Avp promoter in the transgenic rat
brain.
Proper citation: RRID:RGD_626168247 Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=65596
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: |APOA1|APOA1
Source References: PMID: 25561462, PMID: 18688016
Alternate IDs: MMRRC_65596-MU, MMRRC_065596, MMRRC_65596
Notes: Research areas: Cardiovascular; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_065596-MU Copy
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=65582
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Tyr
Alternate IDs: MMRRC_65582-MU, MMRRC_065582, MMRRC_65582
Notes: Research areas: ; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_065582-MU Copy
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