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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
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  • Genomic Alteration:wbgene00001067(dpy-5) (facet)

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Organism Name Proper Citation Species Synonyms Notes Phenotype Affected Gene Genomic Alteration Catalog Number Background Database Database Abbreviation Availability Source References Alternate IDs Authority Record Last Update Mentions Count
VC4098
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00037915 Caenorhabditis elegans hrpk-1(gk5045[loxP + myo-2p::GFP::unc-54 3' UTR + rps-27p::neoR::unc-54 3' UTR + loxP])/tmC18 [dpy-5(tmIs1236)] I. Homozygous lethal deletion balanced by tmC18. Deletion of 1976 bp with Calarco/Colaiacovo selection cassette conferring myo-2 GFP and G418 resistance inserted at break. Left flanking sequence: TCAAAATGATGATCAAAGTGGGAGCCGCTA ; Right flanking sequence: GGTGGATCTGTCTAGGTTCTGGTGTTCGTA. Please reference Au et al., G3 9(1): 135-144 2019 in any work resulting from use of this mutation.|"Homozygous sterile deletion balanced by tmC18. Heterozygotes are wild-type with pharyngeal GFP+RFP+, and segregate GFP+RFP+ heterozygotes, GFP+ gk5045 homozygotes (most commonly sterile, but occasional animals will lay eggs that hatch, and a population of homozygotes can be maintained), and tmC18 homozygotes (Dpy-5 with myo-2 mCherry). Pick fertile wild-type GFP+RFP+ to maintain. Deletion of 1976 bp with Calarco/Colaiacovo selection cassette conferring myo-2 GFP and G418 resistance inserted at break. Left flanking sequence: TCAAAATGATGATCAAAGTGGGAGCCGCTA ; Right flanking sequence: GGTGGATCTGTCTAGGTTCTGGTGTTCGTA. Please reference Au et al., G3 9(1): 135-144 2019 in any work resulting from use of this mutation."|"Made_by: Vancouver KO Group" WBGene00001067(dpy-5)|WBGene00003514(myo-2)|WBGene00004496(rps-27)|WBGene00006789(unc-54)|WBGene00017816(hrpk-1) WBGene00001067(dpy-5), WBGene00003514(myo-2), WBGene00004496(rps-27), WBGene00006789(unc-54), WBGene00017816(hrpk-1) WB-STRAIN:WBStrain00037915 WormBase (WB) WB available WB-STRAIN:VC4098, CGC_VC4098 WormBase 2026-09-26 11:29:48 0
SD63
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00033905 Caenorhabditis elegans dpy-5(e61) unc-13(e51) I; gaDp1 (I;f). Animals with the duplication are WT. Animals which have lost the duplication are DpyUnc. Maintain by picking WT. WBGene00001067(dpy-5)|WBGene00006752(unc-13) WBGene00001067(dpy-5), WBGene00006752(unc-13) WB-STRAIN:WBStrain00033905 WormBase (WB) WB available PMID:8514128 WB-STRAIN:SD63, CGC_SD63 WormBase 2026-09-26 11:28:50 0
SP24
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00034126 Caenorhabditis elegans dpy-5(e61) unc-54(e190) I. DpyUnc. WBGene00001067(dpy-5)|WBGene00006789(unc-54) WBGene00001067(dpy-5), WBGene00006789(unc-54) WB-STRAIN:WBStrain00034126 WormBase (WB) WB available WB-STRAIN:SP24, CGC_SP24 WormBase 2026-09-26 11:28:53 0
SS262
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00034439 Caenorhabditis elegans mes-3(bn35) dpy-5(e61) I; sDp2 (I;f). Animals with the Duplication have a WT phenotype. Animals which have lost the Duplication are Dpy and give sterile Dpy progeny. Strict maternal effect sterile. Sterile worms have a dramatic reduction in number of germs cells (10-100 fold less than WT). See also WBPaper00002343. WBGene00001067(dpy-5)|WBGene00003221(mes-3) WBGene00001067(dpy-5), WBGene00003221(mes-3) WB-STRAIN:WBStrain00034439 WormBase (WB) WB available PMID:1783292 WB-STRAIN:SS262, CGC_SS262 WormBase 2026-09-26 11:28:58 0
src-1(lq185)/tmC20 [unc-14(tmIs1219) dpy-5(tm9715)] I; juIs76 II.
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00062741 Caenorhabditis elegans src-1(lq185)/tmC20 [unc-14(tmIs1219) dpy-5(tm9715)] I; juIs76 II. juIs76 [unc-25p::GFP + lin-15(+)] II. Precise deletion of src-1 generated by Cas9 genome editing. Balancer marked with myo-2p::Venus. Heterozygotes are wild-type with Venus+ pharynx, and will segregate wild-type with Venus+ pharynx (heterozygotes), sterile adults without Venus in pharynx (lq185 homozygotes), and Dpy with Venus+ pharynx (tmC20 homozygotes). GFP expression in GABAergic motor neurons. Reference: Mahadik S, et al. bioRxiv 2023.05.20.541322; doi: https: WBGene00001067(dpy-5)|WBGene00005077(src-1)|WBGene00006753(unc-14) WBGene00001067(dpy-5), WBGene00005077(src-1), WBGene00006753(unc-14) WB-STRAIN:WBStrain00062741 WormBase (WB) WB unknown WormBase 2026-09-26 11:36:09 0
rab-5(udn14)/tmC18 [dpy-5(tmIs1200)] I.
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00050604 Caenorhabditis elegans rab-5(udn14)/tmC18 [dpy-5(tmIs1200)] I. Made_by: UDN Screening Center|"Must be maintained at >20 degrees; grows better at 25C. Homozygous lethal rab-5 [D135H] mutation balanced by tmC18. Balancer marked with myo-2p::Venus. Heterozygotes are WT with pharyngeal Venus fluorescence, and segregate Venus+ heterozygotes, non-Venus rab-5[D135H] homozygotes (L1 lethal), and Dpy Venus+ tmC18 homozygotes. Pick fertile wild-type Venus+ to maintain. Silent BstAPI site added in D135H for genotyping ease. Heterozygous rab-5[D135H] animals are small and have decreased locomotion. Reference: Huang et al. 2022. PMID: 35121658"|"[2022-03-09T03:06:44.75Z WBPerson324] New Strain: rab-5(udn14)/tmC18[dpy5(tmIs1200[myo-2p::Venus])] I"|"[2022-03-09T03:28:46.878Z WBPerson324] Strain: WBPaper00062455; Genotype: rab-5(udn14)/tmC18[dpy5(tmIs1200[myo-2p::Venus])] I" WBGene00001067(dpy-5)|WBGene00004268(rab-5) WBGene00001067(dpy-5), WBGene00004268(rab-5) WB-STRAIN:WBStrain00050604 WormBase (WB) WB unknown PMID:35121658 WormBase 2026-09-26 11:33:03 0
klp-15(ok1958) klp-16(or1952)/tmC18[dpy-5(tmIs1236)] I; ltIs37 IV; ruIs57.
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00050671 Caenorhabditis elegans klp-15(ok1958) klp-16(or1952)/tmC18[dpy-5(tmIs1236)] I; ltIs37 IV; ruIs57. itIs37 [pie-1p::mCherry::H2B::pie-1 3'UTR + unc-119(+)] IV. ruIs57 [pie-1p::GFP::tubulin + unc-119(+)]. tmC18 balancer marked with myo-2p::mCherry and Dpy. Heterozygotes are wild-type with pharyngeal mCherry, and segregate mCherry+ heterozygotes, tmC18 homozygotes (mCherry+ Dpy) and non-mCherry klp-15/16 homozygotes. Homozygous double deletion mutants are fertile but produced reduced brood sizes with highly penetrant embryonic lethality; will also segregate some males. Reference: Chuang CH, et al., Biology Open 2020 9: bio052308 doi: 10.1242/bio.052308 Published 25 June 2020|"ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. ruIs57 [pie-1p::GFP::tubulin + unc-119(+)]. tmC18 balancer marked with myo-2p::mCherry and Dpy. Heterozygotes are wild-type with pharyngeal mCherry, and segregate mCherry+ heterozygotes, tmC18 homozygotes (mCherry+ Dpy) and non-mCherry klp-15/16 homozygotes. Homozygous double deletion mutants are fertile but produced reduced brood sizes with highly penetrant embryonic lethality; will also segregate some males. [NOTE: the ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV transgene was previously annotated as itIs37 in this strain. The correct name of the transgene is ltIs37 and not itIs37.] Reference: Chuang CH, et al., Biology Open 2020 9: bio052308 doi: 10.1242/bio.052308 Published 25 June 2020" WBGene00001067(dpy-5)|WBGene00002225(klp-15)|WBGene00002226(klp-16) WBGene00001067(dpy-5), WBGene00002225(klp-15), WBGene00002226(klp-16) WB-STRAIN:WBStrain00050671 WormBase (WB) WB unknown WormBase 2026-09-26 11:33:04 0
klp-15(ok1958) aspm-1(syb1260[gfp::aspm-1]) klp-16(or1952) /tmC18[dpy-5(tmIs1236)] I; ltIs37[pie-1p::mCherry::H2B::pie-1 3'UTR + unc-119(+)] IV
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00050674 Caenorhabditis elegans klp-15(ok1958) aspm-1(syb1260[gfp::aspm-1]) klp-16(or1952) /tmC18[dpy-5(tmIs1236)] I; ltIs37[pie-1p::mCherry::H2B::pie-1 3'UTR + unc-119(+)] IV itIs37 [pie-1p::mCherry::H2B::pie-1 3'UTR + unc-119(+)] IV. ruIs57 [pie-1p::GFP::tubulin + unc-119(+)]. GFP tag inserted into endogenous aspm-1 locus. tmC18 balancer marked with myo-2p::mCherry and Dpy. Heterozygotes are wild-type with pharyngeal mCherry, and segregate mCherry+ heterozygotes, tmC18 homozygotes (mCherry+ Dpy) and non-mCherry triple mutant homozygotes. Homozygous triple mutants are fertile but produced reduced brood sizes with highly penetrant embryonic lethality; will also segregate some males. Reference: Chuang CH, et al., Biology Open 2020 9: bio052308 doi: 10.1242/bio.052308 Published 25 June 2020|"ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. ruIs57 [pie-1p::GFP::tubulin + unc-119(+)]. GFP tag inserted into endogenous aspm-1 locus. tmC18 balancer marked with myo-2p::mCherry and Dpy. Heterozygotes are wild-type with pharyngeal mCherry, and segregate mCherry+ heterozygotes, tmC18 homozygotes (mCherry+ Dpy) and non-mCherry triple mutant homozygotes. Homozygous triple mutants are fertile but produced reduced brood sizes with highly penetrant embryonic lethality; will also segregate some males. [NOTE: the ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV transgene was previously annotated as itIs37 in this strain. The correct name of the transgene is ltIs37 and not itIs37.] Reference: Chuang CH, et al., Biology Open 2020 9: bio052308 doi: 10.1242/bio.052308 Published 25 June 2020" WBGene00001067(dpy-5)|WBGene00002225(klp-15)|WBGene00002226(klp-16)|WBGene00004027(pie-1)|WBGene00006843(unc-119)|WBGene00008107(aspm-1) WBGene00001067(dpy-5), WBGene00002225(klp-15), WBGene00002226(klp-16), WBGene00004027(pie-1), WBGene00006843(unc-119), WBGene00008107(aspm-1) WB-STRAIN:WBStrain00050674 WormBase (WB) WB unknown WormBase 2026-09-26 11:33:04 0
goa-1(n499)/tmC20 [unc-14(tmIs1219) dpy-5(tm9715)] I.
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00050646 Caenorhabditis elegans goa-1(n499)/tmC20 [unc-14(tmIs1219) dpy-5(tm9715)] I. This strain is difficult and time consuming to maintain. Gives relatively few heterozygotes. Homozygous lethal mutation balanced by Dpy- and myo-2p::Venus-marked inversion. Heterozygotes are paralyzed Unc and Egl with relatively dim pharyngeal GFP (Venus) expression. Heterozygotes segregate heterozygous non-Dpy GFP+ paralyzed Unc and Egl, non-GFP embryonic lethal (homozygous n499), and Dpy with brighter GFP+ (tmC20 homozygous). Remove Dpy from plate to prevent them from taking over. Heterozygotes tend to stack up in parallel clumps. Populations can be enriched by transferring these clumps to new plates and allowing Dpy (tmC20 homozygotes) to crawl out into bacterial lawn, and then picking away Dpy or transferring the clump of Hets to another plate. Derived by balancing n499 from parental strain MT1102 over tmC20 from FX30179. WBGene00001067(dpy-5)|WBGene00001648(goa-1)|WBGene00006753(unc-14) WBGene00001067(dpy-5), WBGene00001648(goa-1), WBGene00006753(unc-14) WB-STRAIN:WBStrain00050646 WormBase (WB) WB unknown WormBase 2026-09-26 11:33:04 0
WM149
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00040443 Caenorhabditis elegans dpy-5(e61) unc-13(e51) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I;III). Heterozygotes are WT with pharyngeal GFP signal, and segragate WT GFP+, arrested hT2 aneuploids, and non-GFP Dpy Unc homozygotes. Homozygous hT2[bli-4 let-? qIs48] are inviable. WBGene00000254(bli-4)|WBGene00001067(dpy-5)|WBGene00006752(unc-13) WBGene00000254(bli-4), WBGene00001067(dpy-5), WBGene00006752(unc-13) WB-STRAIN:WBStrain00040443 WormBase (WB) WB available WB-STRAIN:WM149, CGC_WM149 WormBase 2026-09-26 11:30:31 0
ZZ1004
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00040929 Caenorhabditis elegans unc-63(x18) dpy-5(e61) I. EMPTY WBGene00001067(dpy-5)|WBGene00006797(unc-63) WBGene00001067(dpy-5), WBGene00006797(unc-63) WB-STRAIN:WBStrain00040929 WormBase (WB) WB available WB-STRAIN:ZZ1004, CGC_ZZ1004 WormBase 2026-09-26 11:30:39 0
ZZ1015
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00040931 Caenorhabditis elegans unc-38(x20) dpy-5(e61) I. EMPTY WBGene00001067(dpy-5)|WBGene00006774(unc-38) WBGene00001067(dpy-5), WBGene00006774(unc-38) WB-STRAIN:WBStrain00040931 WormBase (WB) WB available WB-STRAIN:ZZ1015, CGC_ZZ1015 WormBase 2026-09-26 11:30:39 0
gld-1(q343)/unc-11(e47) dpy-5(e61) I
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00054788 Caenorhabditis elegans gld-1(q343)/unc-11(e47) dpy-5(e61) I Heterozygotes are WT and segregate WT, Dpy Uncs, and homozygous q343 (make small abnormal oocytes. Pick WT and check for correct segregation of progeny to maintain. Reference: Francis R, et al. Genetics. 1995 Feb; 139(2): 579606. doi: 10.1093/genetics/139.2.579 PMID: 7713419. WBGene00001067(dpy-5)|WBGene00001595(gld-1)|WBGene00006751(unc-11) WBGene00001067(dpy-5), WBGene00001595(gld-1), WBGene00006751(unc-11) WB-STRAIN:WBStrain00054788 WormBase (WB) WB unknown WormBase 2026-09-26 11:34:03 0
BC13585
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00042266 Caenorhabditis elegans dpy-5(e907) I; sIs13146. Generated based on WC-CalTech XREF data|"No longer available from the CGC catalogue 24/04/2020"|"sIs13146 [rCes C02H7.1::GFP + pCeh361]. Maintain by picking WT. WT animals are GFP+. Strain construction supported by Genome British Columbia and Genome Canada. Please acknowledge McKay et al, Cold Spring Harbor Symposia on Quantitative Biology 68: 159-169 2004 (WBPaper00006525)." WBGene00001067(dpy-5) WBGene00001067(dpy-5) WB-STRAIN:WBStrain00042266 WormBase (WB) WB unknown WB-STRAIN:BC13585 WormBase 2026-09-26 11:31:00 0
dpy-5(e61) I; fjDf1 fjDf2 fjDf3 fjDf4 X.
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00055739 Caenorhabditis elegans dpy-5(e61) I; fjDf1 fjDf2 fjDf3 fjDf4 X. This strain carries a dpy-5 mutation to facilitate genome modification in CeRep55 quadruple deletion background: fjDf1 (also known as fj115); fjDf2 (aka fj85); fjDf3 (aka fj123); fjDf4 (aka fj120) X. This strain lacks four major clusters of CeRep55 repeats on the X chromosome. The condensation of unpaired X chromosomes in male testes is insufficient. CeRep55 is a class of minisatellite sequences consisting of a 27-nt tandem repeat that is present on all chromosomes. Some CeRep55 clusters express long non-coding RNAs and small RNAs. Each of the four deletion sites was designed to acquire a sequence tag (TGTACAGGAAACAGCTATGACC; similar to M13 reverse) instead of the CeRep55 tandem repeats. The deletions of CeRep55 clusters can be checked by PCR with the following primers: fjDf1 in Y73B3A, CAACCTGACTCTCGCCAAGAC and GGAGAAGTAGGCGTGTCAGTTA; fjDf2 in Y75D11A, CAAGTGCCAAACTAGACTGCTC and TTCAAAACGCTACGCGATACCAG; fjDf3 in Y81B9A, AAATGCCCCTATCTCACAGTGG and GACTGCTAGAATCTGACTCGTC; fjDf4 in Y49A10A, CAACCTGACTCTCGCCAAGAC and GGAGAAGTAGGCGTGTCAGTTA. The PCR check can also be performed with the M13 reverse primer and the right-side primer. Reference: Tabara H, et al. (2023) A small RNA system ensures accurate homologous pairing and unpaired silencing of meiotic chromosomes. EMBO J, e105002.|"This strain carries a dpy-5 mutation to facilitate genome modification in CeRep55 quadruple deletion background: fjDf1 (also known as fj115); fjDf2 (aka fj85); fjDf3 (aka fj123); fjDf4 (aka fj120) X. This strain lacks four major clusters of CeRep55 repeats on the X chromosome. The condensation of unpaired X chromosomes in male testes is insufficient. CeRep55 is a class of minisatellite sequences consisting of a 27-nt tandem repeat that is present on all chromosomes. Some CeRep55 clusters express long non-coding RNAs and small RNAs. Each of the four deletion sites was designed to acquire a sequence tag (TGTACAGGAAACAGCTATGACC; similar to M13 reverse) instead of the CeRep55 tandem repeats. The deletions of CeRep55 clusters can be checked by PCR with the following primers: fjDf1 in Y73B3A, CAACCTGACTCTCGCCAAGAC and GGAGAAGTAGGCGTGTCAGTTA; fjDf2 in Y75D11A, CAAGTGCCAAACTAGACTGCTC and TTCAAAACGCTACGCGATACCAG; fjDf3 in Y81B9A, AAATGCCCCTATCTCACAGTGG and GACTGCTAGAATCTGACTCGTC; fjDf4 in Y49A10A, CTCTTCCATTTCCAGTACAACCAG and GTTTCTATGGCTAGAGTCGTATGGTTAC. The PCR check can also be performed with the M13 reverse primer and the right-side primer. Reference: Tabara H, et al. (2023) A small RNA system ensures accurate homologous pairing and unpaired silencing of meiotic chromosomes. EMBO J, e105002." WBGene00001067(dpy-5) WBGene00001067(dpy-5) WB-STRAIN:WBStrain00055739 WormBase (WB) WB unknown WormBase 2026-09-26 11:34:18 0
DR101
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00006182 Caenorhabditis elegans dpy-5(e61) unc-55(e1170) I. Dpy. Unc. Closely Linked. WBGene00001067(dpy-5)|WBGene00006790(unc-55) WBGene00001067(dpy-5), WBGene00006790(unc-55) WB-STRAIN:WBStrain00006182 WormBase (WB) WB available WB-STRAIN:DR101, CGC_DR101 WormBase 2026-09-26 11:21:58 0
DR137
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00006203 Caenorhabditis elegans dpy-5(e61) daf-8(e1393) I. Temperature sensitive dauer constitutive. Dpy. WBGene00000904(daf-8)|WBGene00001067(dpy-5) WBGene00000904(daf-8), WBGene00001067(dpy-5) WB-STRAIN:WBStrain00006203 WormBase (WB) WB available WB-STRAIN:DR137, CGC_DR137 WormBase 2026-09-26 11:21:59 0
DR234
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00006233 Caenorhabditis elegans dpy-5(e61) daf-16(m27) I. Dauer defective. Dpy.|"Made_by: Albert P" WBGene00000912(daf-16)|WBGene00001067(dpy-5) WBGene00000912(daf-16), WBGene00001067(dpy-5) WB-STRAIN:WBStrain00006233 WormBase (WB) WB available WB-STRAIN:DR234, CGC_DR234 WormBase 2026-09-26 11:21:59 0
DR210
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00006226 Caenorhabditis elegans dpy-5(e61) daf-16(m26) unc-75(e950) I. Dauer defective. Dpy. Unc. Leaky. WBGene00000912(daf-16)|WBGene00001067(dpy-5)|WBGene00006807(unc-75) WBGene00000912(daf-16), WBGene00001067(dpy-5), WBGene00006807(unc-75) WB-STRAIN:WBStrain00006226 WormBase (WB) WB available WB-STRAIN:DR210, CGC_DR210 WormBase 2026-09-26 11:21:59 0
DR293
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00006247 Caenorhabditis elegans dpy-5(e61) unc-101(m1) I. Dpy. Unc-paralyzed coiler.|"Made_by: Golden J" WBGene00001067(dpy-5)|WBGene00006829(unc-101) WBGene00001067(dpy-5), WBGene00006829(unc-101) WB-STRAIN:WBStrain00006247 WormBase (WB) WB available WB-STRAIN:DR293, CGC_DR293 WormBase 2026-09-26 11:21:59 0

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