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 PMID:15876356  

Ataxia and peripheral nerve hypomyelination in ADAM22-deficient mice.

Koji Sagane | Kazuhiro Hayakawa | Junko Kai | Tomoko Hirohashi | Eiki Takahashi | Norimasa Miyamoto | Mitsuhiro Ino | Tohru Oki | Kazuto Yamazaki | Takeshi Nagasu
BMC neuroscience | 2005

ADAM22 is a member of the ADAM gene family, but the fact that it is expressed only in the nervous systems makes it unique. ADAM22's sequence similarity to other ADAMs suggests it to be an integrin binder and thus to have a role in cell-cell or cell-matrix interactions. To elucidate the physiological functions of ADAM22, we employed gene targeting to generate ADAM22 knockout mice.

Pubmed ID: 15876356

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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C57BL/6N (tool)

RRID:MGI:2159965

laboratory mouse with name C57BL/6N from MGI.

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