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Activated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is embryonic or perinatal lethal.
Pubmed ID: 18036190
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Curated database of known (published) gene lesions responsible for human inherited disease.
View all literature mentionsCurated database of known (published) gene lesions responsible for human inherited disease.
View all literature mentionsMus musculus with name C57BL/6J from IMSR.
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