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 PMID:21779369  

Transgenic overexpression of Tcfap2c/AP-2gamma results in liver failure and intestinal dysplasia.

Daniel Holl | Peter Kuckenberg | Tatiana Woynecki | Angela Egert | Astrid Becker | Sebastian Huss | Dirk Stabenow | Andreas Zimmer | Percy Knolle | René Tolba | Hans-Peter Fischer | Hubert Schorle
PloS one | 2011

The transcription factor Tcfap2c has been demonstrated to be essential for various processes during mammalian development. It has been found to be upregulated in various undifferentiated tumors and is implicated with poor prognosis. Tcfap2c is reported to impinge on cellular proliferation, differentiation and apoptosis. However, the physiological consequences of Tcfap2c-expression remain largely unknown.

Pubmed ID: 21779369

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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