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 PMID:33012048  

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  2. PMID:33012048

Knockout of the gene encoding the extracellular matrix protein SNED1 results in early neonatal lethality and craniofacial malformations.

Anna Barqué | Kyleen Jan | Emanuel De La Fuente | Christina L Nicholas | Richard O Hynes | Alexandra Naba
Developmental dynamics : an official publication of the American Association of Anatomists | 2021

The extracellular matrix (ECM) is a fundamental component of multicellular organisms that orchestrates developmental processes and controls cell and tissue organization. We previously identified the novel ECM protein SNED1 as a promoter of breast cancer metastasis and showed that its level of expression negatively correlated with breast cancer patient survival. Here, we sought to identify the roles of SNED1 during murine development.

Pubmed ID: 33012048

Research resources used in this publication

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: U54-CA163109
  • Agency: NCI NIH HHS, United States
    Id: P30 CA014051
  • Agency: NCI NIH HHS, United States
    Id: U54 CA163109
  • Agency: Wellcome Trust, United Kingdom
  • Agency: Howard Hughes Medical Institute, United States
  • Agency: NHGRI NIH HHS, United States
    Id: U01 HG004080

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B6(Cg)-Sned1tm1d(KOMP)Wtsi/HynMmjax (organism)

RRID:MMRRC_065815-JAX

Mus musculus with name B6(Cg)-Sned1tm1d(KOMP)Wtsi/HynMmjax from MMRRC.

View all literature mentions

C57BL/6N-Sned1tm1a(KOMP)Wtsi/HynMmjax (organism)

RRID:MMRRC_065813-JAX

Mus musculus with name C57BL/6N-Sned1tm1a(KOMP)Wtsi/HynMmjax from MMRRC.

View all literature mentions

B6(SJL)-Sned1tm1c(KOMP)Wtsi/HynMmjax (organism)

RRID:MMRRC_065814-JAX

Mus musculus with name B6(SJL)-Sned1tm1c(KOMP)Wtsi/HynMmjax from MMRRC.

View all literature mentions

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