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URL: http://www.unc.edu/~yunmli/MaCH-Admix/
Proper Citation: MaCH-Admix (RRID:SCR_009598)
Description: A genotype imputation software that is an extension to MaCH for faster and more flexible imputaiton, especially in admixed populations. It has incorporated a novel piecewise reference selection method to create reference panels tailored for target individual(s). This reference selection method generates better imputation quality in shorter running time. MaCH-Admix also separates model parameter estimation from imputation. The separation allows users to perform imputation with standard reference panels + pre-calibrated parameters in a data independent fashion. Alternatively, if one works with study-specific reference panels, or isolated target population, one has the option to simultaneously estimate these model parameters while performing imputation. MaCH-Admix has included many other useful options and supports VCF input files. All existing MaCH documentation applies to MaCH-Admix.
Synonyms: MaCH-Admix: Genotype Imputation Software
Resource Type: software resource, software application
Defining Citation: PMID:23074066
Keywords: genomic analysis, imaging genomics, imputation, snp, gene, bio.tools
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University of North Carolina at Chapel Hill; North Carolina; USA |
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