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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
University of Iowa; Iowa; USA
 
Resource Report
Resource Website
1+ mentions
University of Iowa; Iowa; USA (RRID:SCR_005011) UI university Public research university in Iowa City, Iowa. Founded in 1847, it is the oldest and the second-largest university in the state. is affiliated with: Big Ten Cancer Research Consortium
is related to: Clinical and Translational Science Awards Consortium
is parent organization of: I/OWA
is parent organization of: Hardin MD
is parent organization of: Non-Rigid Image Registration Evaluation Project
is parent organization of: Brief Psychiatric Rating Scale
is parent organization of: University of Iowa Carver College of Medicine; Iowa; USA
is parent organization of: Hereditary Hearing Loss Homepage
is parent organization of: BRAINSTools
is parent organization of: Bayesian Output Analysis Program
is parent organization of: Brain Research: Analysis of Images, Networks and Systems
is parent organization of: BRAINSDemonWarp
is parent organization of: GTRACT
is parent organization of: University of Iowa Labs and Facilities
is parent organization of: NeuroNEXT
is parent organization of: GazeReader
is parent organization of: Human Thalamus in 3D Stereotactic Coordinates
is parent organization of: University of Iowa Institute of Human Genetics Genomics Division Core Facility
is parent organization of: University of Iowa Roy J Carver Center for Imaging Core Facility
is parent organization of: University of Iowa Roy J Carver Center for Genomics Core Facility
hosts: DSHB
nlx_52860, grid.214572.7, ISNI:0000 0004 1936 8294, Wikidata:Q45133494, Crossref funder ID:100008893 https://ror.org/036jqmy94 SCR_005011 University of Iowa 2026-08-01 12:02:52 8
Pythia
 
Resource Report
Resource Website
10+ mentions
Pythia (RRID:SCR_004952) software resource Pythia is an open source thermodynamically oriented primer design python module. Pythia can be used in two ways. 1. Executable binaries only: under windows with cygwin and python 2.5 (built with mingw, that comes with the cygwin release). These executables allow the user to index DNA files for primer specificity search, design one primer pair per region, and tile regions with PCR amplicons. 2. A python module: under windows with cygwin, python2.5, numpy, swig, and mingw, or under linux with python2.4 or later, numpy, and swig (everything but numpy should be pre-installed on a normal linux system). The module gets you everything that the binaries get you, in a more pythonic framework. This package also includes modules for computing DNA binding and folding energies using the partition function approach with publicly available thermodynamic data. Usage documentation is in the downloads. has parent organization: SourceForge PMID:19528077 nlx_91969 SCR_004952 2026-08-01 12:02:47 42
SLIQ
 
Resource Report
Resource Website
1+ mentions
SLIQ (RRID:SCR_005003) SLIQ software resource Software for simple linear inequalities based Mate-Pair reads filtering and scaffolding. A set of simple linear inequalities (SLIQ) derived from the geometry of contigs on the line that can be used to predict the relative positions and orientations of contigs from individual mate pair reads and thus produce a contig digraph. The SLIQ inequalities can also filter out unreliable mate pairs and can be used as a pre-processing step for any scaffolding algorithm. This tool filters mate pairs and then produces a Directed Contig Graph (contig diGraph). Also provided is a Naive scaffolder that can then produce scaffolds out of the contig diGraph. python, scaffolding, contig position, contig orientation, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:23057825 biotools:sliq, OMICS_00048 https://bio.tools/sliq SCR_005003 Simple linear inequalities, SLiQ: Simple linear inequalities based Mate-Pair reads filtering and scaffolding 2026-08-01 12:02:51 3
cortex var
 
Resource Report
Resource Website
1+ mentions
cortex var (RRID:SCR_005081) cortex_var software resource A tool for genome assembly and variation analysis from sequence data. You can use it to discover and genotype variants on single or multiple haploid or diploid samples. If you have multiple samples, you can use Cortex to look specifically for variants that distinguish one set of samples (eg phenotype=X, cases, parents, tumour) from another set of samples (eg phenotype=Y, controls, child, normal). cortex_var features * Variant discovery by de novo assembly - no reference genome required * Supports multicoloured de Bruijn graphs - have multiple samples loaded into the same graph in different colours, and find variants that distinguish them. * Capable of calling SNPs, indels, inversions, complex variants, small haplotypes * Extremely accurate variant calling - see our paper for base-pair-resolution validation of entire alleles (rather than just breakpoints) of SNPs, indels and complex variants by comparison with fully sequenced (and finished) fosmids - a level of validation beyond that demanded of any other variant caller we are aware of - currently cortex_var is the most accurate variant caller for indels and complex variants. * Capable of aligning a reference genome to a graph and using that to call variants * Support for comparing cases/controls or phenotyped strains * Typical memory use: 1 high coverage human in under 80Gb of RAM, 1000 yeasts in under 64Gb RAM, 10 humans in under 256 Gb RAM genome assembly, variation analysis, sequence, variation, genotype variant, haploid, diploid, snp, indel, inversion, variant, haplotype, de novo assembly, genotyping, variant-calling, population analysis, population assembly is listed by: OMICtools
has parent organization: SourceForge
has parent organization: Wellcome Trust Centre for Human Genetics
PMID:22231483 GNU General Public License, v3, Acknowledgement requested OMICS_00056 SCR_005081 cortex_var - for variant and population assembly 2026-08-01 12:02:54 3
Applied Biosystems
 
Resource Report
Resource Website
10000+ mentions
Applied Biosystems (RRID:SCR_005039) commercial organization An Antibody supplier is parent organization of: Ambion Inc. nlx_152278 SCR_005039 2026-08-01 12:02:48 32510
SOPRA
 
Resource Report
Resource Website
10+ mentions
SOPRA (RRID:SCR_005035) SOPRA software resource Software tool to exploit the mate pair/paired-end information for assembly of short reads from high throughput sequencing platforms, e.g. Illumina and SOLiD. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:20576136 Acknowledgement requested biotools:sopra, OMICS_00049 https://bio.tools/sopra SCR_005035 SOPRA - Statistical Optimization of Paired Read Assembly, Statistical Optimization of Paired Read Assembly 2026-08-01 12:02:48 20
Bioworld Technology
 
Resource Report
Resource Website
1+ mentions
Bioworld Technology (RRID:SCR_005036) commercial organization An Antibody supplier nlx_152317 SCR_005036 2026-08-01 12:02:52 1
SSPACE
 
Resource Report
Resource Website
100+ mentions
SSPACE (RRID:SCR_005056) SSPACE software resource A stand-alone software program for scaffolding pre-assembled contigs using paired-read data. Main features are: a short runtime, multiple library input of paired-end and/or mate pair datasets and possible contig extension with unmapped sequence reads. scaffolding, contig, genome, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21149342
DOI:10.1093/bioinformatics/btq683
GNU General Public License, Registration required biotools:sspace, OMICS_00050 https://bio.tools/sspace, https://sources.debian.org/src/sspace/ SCR_005056 2026-08-01 12:02:53 426
HPC-CLUST
 
Resource Report
Resource Website
1+ mentions
HPC-CLUST (RRID:SCR_005052) HPC-CLUST software resource A set of tools designed to cluster large numbers (>1 million) of pre-aligned nucleotide sequences. It performs the clustering of sequences using the Hierarchical Clustering Algorithm (HCA). There are currently three different cluster metrics implemented: single-linkage, complete-linkage, and average-linkage. In addition, there are currently four sequence distance functions implemented, these are: identity (gap-gap counting as match), nogap (gap-gap being ignored), nogap-single (like nogap, but consecutive gap-nogap''s count as a single mismatch), tamura (distance is calculated with the knowledge that transitions are more likely than transversions). One advantage that HCA has over other algorithms is that instead of producing only the clustering at a given threshold, it produces the set of merges occuring at each threshold. With this approach, the clusters can afterwards very quickly be reported for every arbitrary threshold with little extra computation. This approach also allows the plotting of the variation of number of clusters with clustering threshold without requiring the clustering to be run for each threshold independently. Another feature of the way HPC-CLUST is implemented is that the single-, complete-, and average-linkage clusterings can be computed in a single run with little overhead. c++, mpi is listed by: OMICtools
has parent organization: University of Zurich; Zurich; Switzerland
PMID:24215029 OMICS_01446 SCR_005052 2026-08-01 12:02:48 5
University of Manchester; Manchester; United Kingdom
 
Resource Report
Resource Website
1+ mentions
University of Manchester; Manchester; United Kingdom (RRID:SCR_004996) university Public research university in Manchester, England, formed in 2004 by merger of University of Manchester Institute of Science and Technology and Victoria University of Manchester. Second largest university in United Kingdom by enrollment. is affiliated with: OpenMinTeD
is related to: NEWMEDS
is related to: ORBITO
is related to: Open PHACTS
is related to: EMIF
is parent organization of: Smart Dictionary Lookup
is parent organization of: mlgt
is parent organization of: Utopia Docs
is parent organization of: Kidney and Urinary Pathway Knowledge Base
is parent organization of: PUMA
is parent organization of: DOSY Toolbox
is parent organization of: RightField
is parent organization of: SEEK
is parent organization of: miRBase
is parent organization of: PRINTS
is parent organization of: CHEM21
is parent organization of: Taverna
is parent organization of: SysMO-DB
is parent organization of: MethodBox
is parent organization of: OWL API
is parent organization of: X:MAP
is parent organization of: Mimas
is parent organization of: National Centre for Text Mining
is parent organization of: Chemistry Using Text Annotations
is parent organization of: TerMine
is parent organization of: Acromine Disambiguator
is parent organization of: Census Dissemination Unit
is parent organization of: Open Regulatory Annotation Database
is parent organization of: ADAPT: A Database of Affymetrix Probesets and Transcripts
is parent organization of: brat rapid annotation tool
is parent organization of: UK DNA Banking Network
is parent organization of: AcroMine
is parent organization of: BioIE: Extracting Informative Sentences From the Biomedical Literature
is parent organization of: Biocatalogue - The Life Science Web Services Registry
is parent organization of: myExperiment
is parent organization of: Software Ontology
is parent organization of: bioNerDS
is parent organization of: MorphoJ
is parent organization of: University of Manchester Bioinformatics Core Facility
is parent organization of: miRBase
is parent organization of: Simple Assignment of Spots to Surfaces
is parent organization of: AMBER parameter database
is parent organization of: University of Manchester Electron Microscopy Core Facility
is parent organization of: University of Manchester Mass Spectrometry and Separations Core Facility
is parent organization of: University of Manchester Advanced Manufacturing Platform Core Facility
is parent organization of: University of Manchester Surface Characterisation Core Facility
is parent organization of: University of Manchester Biochemical and Biophysical Sciences Technology Platform Core Facility
is parent organization of: University of Manchester Corrosion and Materials for Demanding Environments Core Facility
is parent organization of: University of Manchester Magnetic Resonance and Related Technology Platform Core Facility
is parent organization of: University of Manchester X-ray Diffraction Platform Core Facility
is parent organization of: University of Manchester Services and Equipment Core Facility
is parent organization of: University of Manchester Design, Fabrication and Testing Core Facility
is parent organization of: University of Manchester National X-ray Computed Tomography Core Facility
is parent organization of: University of Manchester Advanced Metal Development Core Facility
is parent organization of: University of Manchester BioAutomation and Biofoundry Core Facility
is parent organization of: University of Manchester Biomolecular NMR Core Facility
has organization facet: MANC-RISK-SCREEN
nlx_74265, Wikidata:Q230899, grid.5379.8, ISNI:121662407, Crossref funder ID:501100000770 https://ror.org/027m9bs27 SCR_004996 University of Manchester 2026-08-01 12:02:44 7
Bio X Cell
 
Resource Report
Resource Website
1000+ mentions
Bio X Cell (RRID:SCR_004997) commercial organization Commercial supplier and developer of in vivo antibodies. Provides antibodies and antibody production services. commercial, antibody, reagent, biomedical, research, new hampshire, SCR_019248, nlx_152318 SCR_004997 2026-08-01 12:02:47 4386
ESPRIT-Tree
 
Resource Report
Resource Website
1+ mentions
ESPRIT-Tree (RRID:SCR_005045) ESPRIT-Tree software resource Software for hierarchical Clustering Analysis of Millions of 16S rRNA Pyrosequences in Quasi-linear Time. clustering, 16s rrna, pyrosequence is listed by: OMICtools
has parent organization: University of Florida; Florida; USA
PMID:21596775 OMICS_01445 SCR_005045 ESPRIT-Tree: Hierarchical Clustering Analysis of Millions of 16S rRNA Pyrosequences in Quasi-linear Time 2026-08-01 12:02:53 9
MBCluster.Seq
 
Resource Report
Resource Website
1+ mentions
MBCluster.Seq (RRID:SCR_005079) MBCluster.Seq software resource Software to cluster genes based on Poisson or Negative-Binomial model for RNA-Seq or other digital gene expression (DGE) data. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24191069 GNU General Public License, >/=v3 OMICS_01417, biotools:mbcluster.seq https://bio.tools/mbcluster.seq SCR_005079 MBCluster.Seq: Model-Based Clustering for RNA-seq Data 2026-08-01 12:02:48 1
AGORA
 
Resource Report
Resource Website
50+ mentions
AGORA (RRID:SCR_005070) AGORA software resource An algorithm to use optical map information directly within the de Bruijn graph framework to help produce an accurate assembly of a genome that is consistent with the optical map information provided. AGORA takes as input two data structures: OpMap ? an ordered list of fragment sizes representing the optical map; and Edges ? a list of de Bruijn graph edges with their corresponding sequences. genome assembly, genome, reconstruction is listed by: OMICtools PMID:22856673 OMICS_00039 SCR_005070 Assembly Guided by Optical Restriction Alignment 2026-08-01 12:02:45 99
GRASS
 
Resource Report
Resource Website
50+ mentions
GRASS (RRID:SCR_005071) GRASS software resource A generic algorithm for scaffolding next-generation sequencing assemblies. next-generation sequencing, scaffolding, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:22492642 GNU General Public License, v3 biotools:GRASS, OMICS_00043 https://bio.tools/GRASS SCR_005071 GRASS: a generic algorithm for scaffolding next-generation sequencing assemblies, GeneRic ASembly Scaffolder 2026-08-01 12:02:48 89
MapAl
 
Resource Report
Resource Website
1+ mentions
MapAl (RRID:SCR_004938) MapAl software resource A software tool for RNA-Seq expression profiling that builds on the established programs Bowtie and Cufflinks. Allowing an incorporation of ''gene models'' already at the alignment stage almost doubles the number of transcripts that can be measured reliably. rna?seq is listed by: OMICtools
has parent organization: BOKU University; Vienna; Austria
PMID:22485116 GNU General Public License OMICS_01261 SCR_004938 2026-08-01 12:02:43 1
Open University; Milton Keynes; United Kingdom
 
Resource Report
Resource Website
1+ mentions
Open University; Milton Keynes; United Kingdom (RRID:SCR_004931) OU university Public research university and the largest university in the UK for undergraduate education. The majority of the OU's undergraduate students are based in the United Kingdom and principally study off-campus; many of its courses can also be studied anywhere in the world. is affiliated with: OpenMinTeD
is parent organization of: Scholarly Ontologies Project
is parent organization of: Cohere
is parent organization of: Rexplore
Wikidata:Q2413375, nlx_19814, grid.10837.3d, ISNI:96069301, Crossref funder ID:100008509 https://ror.org/05mzfcs16 SCR_004931 Open University, The Open University 2026-08-01 12:02:43 3
University of Iowa Carver College of Medicine; Iowa; USA
 
Resource Report
Resource Website
1+ mentions
University of Iowa Carver College of Medicine; Iowa; USA (RRID:SCR_005064) UI Carver College of Medicine university Medical school of the University of Iowa, located in Iowa City, in the U.S. state of Iowa. has parent organization: University of Iowa; Iowa; USA
is parent organization of: MADS+ - discovery of differential splicing events from Affymetrix exon junction array data
is parent organization of: University of Iowa College of Medicine Department of Pharmacology
is parent organization of: University of Iowa Magnetic Resonance Research Facility
is parent organization of: University of Iowa Center for Gene Therapy Vectore Core
is parent organization of: University of Iowa Center for Gene Therapy Clinical Core
is parent organization of: University of Iowa Center for Gene Therapy Animal Model Core
is parent organization of: University of Iowa Center for Gene Therapy
is parent organization of: University of Iowa Center for Gene Therapy Comparative Pathology Core
is parent organization of: University of Iowa Center for Gene Therapy Cell Tissue Core
nlx_68753 SCR_005064 University of Iowa Carver College of Medicine, Roy J. and Lucille A. Carver College of Medicine 2026-08-01 12:02:53 1
Stanford Research Institute International
 
Resource Report
Resource Website
1+ mentions
Stanford Research Institute International (RRID:SCR_004926) SRI institution Independent, nonprofit research institute conducting client sponsored research and development for government agencies, commercial businesses, foundations, and other organizations. SRI also brings its innovations to the marketplace by licensing its intellectual property and creating new ventures. SRI was founded as Stanford Research Institute in 1946 by a group of West Coast industrialists and Stanford University. SRI formally separated from the University in 1970, and we changed our name to SRI International in 1977. is related to: Stanford University; Stanford; California
is parent organization of: BioCyc
is parent organization of: NIMH Toxicological Screens of Novel Ligands
is parent organization of: Project Halo
is parent organization of: EcoCyc
is parent organization of: NCANDA: Data Integration Component
is parent organization of: SRI24 Atlas: Normal Adult Brain Anatomy
is parent organization of: HumanCyc: Encyclopedia of Homo sapiens Genes and Metabolism
is parent organization of: MetaCyc
nif-0000-00235 SCR_004926 SRI International, Stanford Research Institute 2026-08-01 12:02:49 2
SLIDE
 
Resource Report
Resource Website
10+ mentions
SLIDE (RRID:SCR_005137) SLIDE software resource Software package that takes exon boundaries and RNA-Seq data as input to discern the set of mRNA isoforms that are most likely to present in an RNA-Seq sample. It is based on a linear model with a design matrix that models the sampling probability of RNA-Seq reads from different mRNA isoforms. To tackle the model unidentifiability issue, SLIDE uses a modified Lasso procedure for parameter estimation. Compared with deterministic isoform assembly algorithms (e.g., Cufflinks), SLIDE considers the stochastic aspects of RNA-Seq reads in exons from different isoforms and thus has increased power in detecting more novel isoforms. Another advantage of SLIDE is its flexibility of incorporating other transcriptomic data such as RACE, CAGE, and EST into its model to further increase isoform discovery accuracy. SLIDE can also work downstream of other RNA-Seq assembly algorithms to integrate newly discovered genes and exons. Besides isoform discovery, SLIDE sequentially uses the same linear model to estimate the abundance of discovered isoforms. is listed by: OMICtools
has parent organization: University of California at Berkeley; Berkeley; USA
NIH ;
NHGRI HG004695;
NHGRI HG005639;
NEI EY019094
PMID:22135461 OMICS_01291 SCR_005137 sparse linear modeling of RNA-Seq data for isoform discovery and abundance estimation 2026-08-01 12:02:49 32

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