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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
BatMeth
 
Resource Report
Resource Website
1+ mentions
BatMeth (RRID:SCR_010906) BatMeth software resource Improved mapper for bisulfite sequencing reads on DNA methylation. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Google Code
biotools:batmeth, OMICS_00574 https://bio.tools/batmeth SCR_010906 SciCrunch Registry 2026-11-07 11:56:58 1
QUMA
 
Resource Report
Resource Website
100+ mentions
QUMA (RRID:SCR_010907) QUMA software resource You can easily align, visualize and quantify bisulfite sequence data for CpG methylation analysis. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
OMICS_00588, biotools:quma https://bio.tools/quma SCR_010907 SciCrunch Registry QUantification tool for Methylation Analysis 2026-11-07 11:57:07 398
PeakRanger
 
Resource Report
Resource Website
10+ mentions
PeakRanger (RRID:SCR_010863) PeakRanger software resource Software for a multi-purpose ChIP Seq peak caller. mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21554709 OMICS_00451, biotools:peakranger https://bio.tools/peakranger SCR_010863 SciCrunch Registry 2026-11-07 11:57:05 21
SEAL
 
Resource Report
Resource Website
100+ mentions
SEAL (RRID:SCR_010914) SEAL software resource A suite of distributed software applications for aligning short DNA reads, and manipulating and analyzing short read alignments. mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:21697132 biotools:seal, OMICS_00682 https://bio.tools/seal SCR_010914 SciCrunch Registry 2026-11-07 11:57:07 121
DIME
 
Resource Report
Resource Website
10+ mentions
DIME (RRID:SCR_010874) DIME software resource R-package for identifying differential ChIP-seq based on an ensemble of mixture models. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
biotools:DIME, OMICS_00473 https://bio.tools/DIME SCR_010874 SciCrunch Registry 2026-11-07 11:56:57 31
BWA
 
Resource Report
Resource Website
1000+ mentions
BWA (RRID:SCR_010910) BWA alignment software, data analysis software, data processing software, image analysis software, sequence analysis software, software application, software resource Software for aligning sequencing reads against large reference genome. Consists of three algorithms: BWA-backtrack, BWA-SW and BWA-MEM. First for sequence reads up to 100bp, and other two for longer sequences ranged from 70bp to 1Mbp. sequence, alignment, reference, genome, human, short, long, read, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: shovill
is related to: Proovread
is related to: BWA-MEM2
has parent organization: SourceForge
is required by: RelocaTE
PMID:19451168
PMID:20080505
DOI:10.1093/bioinformatics/btp324
Free, Available for download, Freely available SCR_015853, biotools:bwa-sw, OMICS_00654 https://sourceforge.net/projects/bio-bwa/files/, https://bio.tools/bwa-sw, https://sources.debian.org/src/bwa/ SCR_010910 SciCrunch Registry Burrows-Wheeler Aligner (BWA), Burrows-Wheeler Aligner 2026-11-07 11:57:07 2638
CloudBurst
 
Resource Report
Resource Website
CloudBurst (RRID:SCR_010911) CloudBurst software resource A new parallel read-mapping algorithm optimized for mapping next-generation sequence data to the human genome and other reference genomes, for use in a variety of biological analyses including SNP discovery, genotyping, and personal genomics. mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:19357099 Free OMICS_00657, biotools:cloudburst https://bio.tools/cloudburst SCR_010911 SciCrunch Registry 2026-11-07 11:56:58 0
MACAT
 
Resource Report
Resource Website
MACAT (RRID:SCR_001350) MACAT software resource Software library that contains functions to investigate links between differential gene expression and the chromosomal localization of the genes. It is motivated by the common observation of phenomena involving large chromosomal regions in tumor cells. MACAT is the implementation of a statistical approach for identifying significantly differentially expressed chromosome regions. differential expression, microarray, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:15572464 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01989, biotools:macat https://bio.tools/macat SCR_001350 SciCrunch Registry MicroArray Chromosome Analysis Tool 2026-11-07 11:54:28 0
lapmix
 
Resource Report
Resource Website
lapmix (RRID:SCR_001347) lapmix software resource Software to identify differentially expressed genes. A hierarchical Bayesian approach is used, and the hyperparameters are estimated using empirical Bayes. differential expression, microarray, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available biotools:lapmix, OMICS_01992 https://bio.tools/lapmix SCR_001347 SciCrunch Registry Laplace Mixture Model in Microarray Experiments 2026-11-07 11:54:29 0
FARMS
 
Resource Report
Resource Website
10+ mentions
FARMS (RRID:SCR_001344) FARMS software resource Software using a model-based technique for summarizing high-density oligonucleotide array data at probe level for Affymetrix GeneChips. It is based on a factor analysis model for which a Bayesian maximum a posteriori method optimizes the model parameters under the assumption of Gaussian measurement noise. oligonucleotide array, probe, affymetrix genechip, r, unix, windows, microarray, summarization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Johannes Kepler University of Linz; Linz; Austria
PMID:16473874 Free, Freely Available OMICS_01995, biotools:farms https://bio.tools/farms SCR_001344 SciCrunch Registry Factor Analysis for Robust Microarray Summarization 2026-11-07 11:54:22 28
bridge
 
Resource Report
Resource Website
100+ mentions
bridge (RRID:SCR_001343) bridge software resource Software package to test for differentially expressed genes with microarray data. It can be used with both cDNA microarrays or Affymetrix chip. The packge fits a robust Bayesian hierarchical model for testing for differential expression. Outliers are modeled explicitly using a $t$-distribution. The model includes an exchangeable prior for the variances which allow different variances for the genes but still shrink extreme empirical variances. The model can be used for testing for differentially expressed genes among multiple samples, and can distinguish between the different possible patterns of differential expression when there are three or more samples. Parameter estimation is carried out using a novel version of Markov Chain Monte Carlo that is appropriate when the model puts mass on subspaces of the full parameter space. cdna microarray, affymetrix chip, differential expression, microarray, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:16542223 Free, Available for download, Freely available OMICS_01996, biotools:bridge http://www.bioconductor.org/packages/release/bioc/html/bridge.html SCR_001343 SciCrunch Registry Bayesian Robust Inference for Differential Gene Expression 2026-11-07 11:54:29 157
vsn
 
Resource Report
Resource Website
1+ mentions
vsn (RRID:SCR_001459) vsn software resource Software package that implements a method for normalizing microarray intensities, both between colours within array, and between arrays. The method uses a robust variant of the maximum-likelihood estimator for the stochastic model of microarray data described in the references. The model incorporates data calibration (a.k.a. normalization), a model for the dependence of the variance on the mean intensity, and a variance stabilizing data transformation. Differences between transformed intensities are analogous to normalized log-ratios. However, in contrast to the latter, their variance is independent of the mean, and they are usually more sensitive and specific in detecting differential transcription. microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: European Bioinformatics Institute
Free, Available for download, Freely available OMICS_01977, biotools:vsn https://bio.tools/vsn SCR_001459 SciCrunch Registry vsn - Variance stabilization and calibration for microarray data 2026-11-07 11:54:31 6
UNAFold
 
Resource Report
Resource Website
100+ mentions
UNAFold (RRID:SCR_001360) data analysis software, data processing software, software application, software resource Software package for nucleic acid folding and hybridization prediction. It has capabilities to predict folding for single-stranded RNA or DNA through a combination of free energy minimization, partition function calculations and stochastic sampling. The program runs on Unix and Linux platforms as well as Mac OS X and Windows. software, nucleic acid, folding, hybridization, prediction, rna, dna, stochastic sampling, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University at Albany; New York; USA
Free, Available for download, Freely available biotools:unafold, nif-0000-07753 http://mfold.rna.albany.edu/ SCR_001360 SciCrunch Registry The UNAFold Web Server, UNAFold Web Server 2026-11-07 11:54:29 373
Happy
 
Resource Report
Resource Website
10+ mentions
Happy (RRID:SCR_001395) HAPPY data analysis software, data processing software, software application, software resource, source code THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software package for Multipoint QTL Mapping in Genetically Heterogeneous Animals (entry from Genetic Analysis Software) The method is implemented in a C-program and there is now an R version of HAPPY. You can run HAPPY remotely from their web server using your own data (or try it out on the data provided for download). qtl, quantitative trait locus, r, c, gene, genetic, genomic, ansi c, unix, irix, sunos, linux, animal model, trait, map, genotype, phenotype, haplotype, linear regression, data set, qtl mapping is listed by: Genetic Analysis Software
is listed by: Debian
has parent organization: Wellcome Trust Centre for Human Genetics
Wellcome Trust PMID:11050180
DOI:10.1073/pnas.230304397
THIS RESOURCE IS NO LONGER IN SERVICE nlx_152594 http://www.well.ox.ac.uk/~rmott/happy.html https://sources.debian.org/src/r-other-mott-happy.hbrem/ SCR_001395 SciCrunch Registry reconstructing HAPlotYpes 2026-11-07 11:54:24 46
aroma.light
 
Resource Report
Resource Website
1+ mentions
aroma.light (RRID:SCR_001312) aroma.light software resource Light-weight software package for normalization and visualization of microarray data using only basic R data types. Software can be used standalone, be utilized in other packages, or be wrapped up in higher-level classes. infrastructure, microarray, preprocessing, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
DOI:10.1186/1471-2105-11-245 Free, Available for download, Freely available OMICS_01998, biotools:aroma.light https://bio.tools/aroma.light, https://sources.debian.org/src/r-bioc-aroma.light/ SCR_001312 SciCrunch Registry 2026-11-07 11:54:29 1
BeadDataPackR
 
Resource Report
Resource Website
BeadDataPackR (RRID:SCR_001310) BeadDataPackR software resource Software that provides functionality for the compression and decompression of raw bead-level data from the Illumina BeadArray platform. microarray, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:20981138 Free, Available for download, Freely available biotools:beaddatapackr, OMICS_02023 https://bio.tools/beaddatapackr SCR_001310 SciCrunch Registry BeadDataPackR - Compression of Illumina BeadArray data 2026-11-07 11:54:26 0
OLIN
 
Resource Report
Resource Website
10+ mentions
OLIN (RRID:SCR_001304) OLIN software resource Software functions for normalization of two-color microarrays by optimised local regression and for detection of artifacts in microarray data. r, normalization, visualization, quality control, two-channel, microarray, preprocessing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Humboldt University of Berlin; Berlin; Germany
has parent organization: Bioconductor
PMID:15585527 Free, Available for download, Freely available biotools:olin, OMICS_02029 http://itb.biologie.hu-berlin.de/~futschik/software/R/OLIN/index.html SCR_001304 SciCrunch Registry Optimised Local Intensity-dependent Normalisation 2026-11-07 11:54:21 18
qcmetrics
 
Resource Report
Resource Website
1+ mentions
qcmetrics (RRID:SCR_001303) qcmetrics software resource Software package that provides a framework for generic quality control of data. It permits to create, manage and visualise individual or sets of quality control metrics and generate quality control reports in various formats. mass spectrometry, microarray, proteomics, quality control, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02032, biotools:qcmetrics, BioTools:qcmetrics https://bio.tools/qcmetrics, https://bio.tools/qcmetrics, https://bio.tools/qcmetrics SCR_001303 SciCrunch Registry qcmetrics - A Framework for Quality Control 2026-11-07 11:54:28 1
DEXUS
 
Resource Report
Resource Website
1+ mentions
DEXUS (RRID:SCR_001309) DEXUS software resource Software package that identifies differentially expressed genes in RNA-Seq data under all possible study designs such as studies without replicates, without sample groups, and with unknown conditions. It works also for known conditions, for example for RNA-Seq data with two or multiple conditions. RNA-Seq read count data can be provided both by the S4 class Count Data Set and by read count matrices. Differentially expressed transcripts can be visualized by heatmaps, in which unknown conditions, replicates, and samples groups are also indicated. This software is fast since the core algorithm is written in C. For very large data sets, a parallel version of DEXUS is provided in this package. DEXUS is a statistical model that is selected in a Bayesian framework by an EM algorithm. It does not need replicates to detect differentially expressed transcripts, since the replicates (or conditions) are estimated by the EM method for each transcript. The method provides an informative/non-informative value to extract differentially expressed transcripts at a desired significance level or power. classification, differential expression, gene expression, hapmap, quality control, rna-seq, sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:24049071 Free, Available for download, Freely available biotools:dexus, OMICS_02024 http://www.bioconductor.org/packages/release/bioc/html/dexus.html SCR_001309 SciCrunch Registry DEXUS - Identifying Differential Expression in RNA-Seq Studies with Unknown Conditions or without Replicates 2026-11-07 11:54:15 1
Mugsy
 
Resource Report
Resource Website
50+ mentions
Mugsy (RRID:SCR_001414) data analysis software, data processing software, sequence analysis software, software application, software resource Software resource for multiple whole genome alignment. It uses Nucmer, a custom graph-based segmentation procedure, for pairwise alignment, and the Seqan:TCoffee's multiple alignment strategy. software, genome, genome alignment, segmentation, pairwise alignment, sequence analysis software is listed by: OMICtools
is listed by: Debian
has parent organization: SourceForge
PMID:21148543
DOI:10.1093/bioinformatics/btq665
Free, Available for download, Freely available OMICS_03606 https://sources.debian.org/src/mugsy/ SCR_001414 SciCrunch Registry 2026-11-07 11:54:18 75

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