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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Optseq
 
Resource Report
Resource Website
100+ mentions
Optseq (RRID:SCR_014363) data acquisition software, data processing software, software application, software resource, standalone software Software tool for automatically scheduling events for rapid-presentation event-related (RPER) fMRI experiments (the schedule is the order and timing of events). Events in RPER are presented closely enough in time that their hemodynamic responses will overlap. This requires that the onset times of the events be jittered in order to remove the overlap from the estimate of the hemodynamic response. RPER is highly resistant to habituation, expectation, and set because the subject does not know when the next stimulus will appear or which stimulus type it will be. fmri, scheduling event, event, rper, hemodynamic response, stimulus, stochastic design is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Available for download SCR_005976, nlx_151349 http://www.nitrc.org/projects/optseq SCR_014363 Optseq2, Optseq - fMRI Event Scheduler 2026-09-19 12:52:56 341
ENIGMA-DTI Pipeline
 
Resource Report
Resource Website
50+ mentions
ENIGMA-DTI Pipeline (RRID:SCR_014649) protocol Pipeline which provides tools to extract whole-brain average and regional measurements from DTI images including FA, AD, RD and MD. Protocols for preprocessing, ENIGMA-DTI processing (skeletonization and ROI extraction), and GWAS analysis are available. Software tools used for each process are listed within the protocols. dti, enigma, protocol, pipeline is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Southern California; Los Angeles; USA
has parent organization: ENIGMA
NIBIB U54 EB020403 Available for download from NITRC http://www.nitrc.org/projects/enigma_dti SCR_014649 ENIGMA-DTI protocol, ENIGMA DTI pipeline, ENIGMA DTI protocol 2026-09-19 12:53:00 50
Group Sparse Canonical Correlation Analysis
 
Resource Report
Resource Website
Group Sparse Canonical Correlation Analysis (RRID:SCR_014977) GSCCA data analysis software, data processing software, software application, software resource Group Sparse Canonical Correlation Analysis is a method designed to study the mutual relationship between two different types of data. group analysis, correlation analysis has parent organization: NeuroImaging Tools and Resources Collaboratory (NITRC) NSF ;
NIH
Available for download SCR_014977 2026-09-19 12:53:04 0
Mixed Effect Model of Genetic-Set and Environment Interaction
 
Resource Report
Resource Website
Mixed Effect Model of Genetic-Set and Environment Interaction (RRID:SCR_015514) data or information resource, model, software resource, software toolkit MATLAB Toolbox which provides a mixed effect model for gene-environment interaction (MixGE) on neuroimaging phenotypes, such as structural volumes and tensor-based morphometry (TBM). This model incorporates both fixed and random effects of genetic-set and environment interaction in order to investigate homogeneous and heterogeneous contributions of sets of genetic variants and their interactions with environmental risks to phenotypes. gene environment interaction, gene environment interaction model, neuroimaging phenotype uses: MATLAB
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: National University of Singapore; Singapore; Singapore
Singapore National Research Foundation Singapore-NMRC/TCR/004-NUS/2008;
Singapore National Research Foundation Singapore-NMRC/TCR/012-NUHS/2014;
Singapore Ministry of Health National Medical Research Council NMRC/CBRG/0039/2013;
Singapore Ministry of Education Academic Research Fund Tier 2 MOE2012-T2-2-130
Free for non-commercial use SCR_015514 Mixed Effect Model of Genetic Set and Environment Interaction, Mixed Effect Model of Genetic Set and Environment Interaction Toolbox, MixGE Toolbox 2026-09-19 12:53:09 0
Faceted Search Based Ontology Visualizer
 
Resource Report
Resource Website
Faceted Search Based Ontology Visualizer (RRID:SCR_000124) ontologyviz software resource Software that allows user to do faceted search on an ontology and enables visualization of the search results on the 3D digital atlas. Currently supports faceted search of functional neuroanatomy. computational neuroscience, magnetic resonance, ontology, functional neuroanatomy, facet, visualization is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Free, Freely available nlx_155874 SCR_000124 2026-09-19 12:49:16 0
3DMeshMetric
 
Resource Report
Resource Website
1+ mentions
3DMeshMetric (RRID:SCR_000043) 3DMeshMetric data processing software, data visualization software, software application, software resource Software visualization tool based on the VTK library. Its main feature is to measure and display surface-to-surface distance between two triangle meshes using user-specified uniform sampling. Offers all the basic tools to visualize meshes such as color, opacity, smoothing, down sampling or type of representation. visualize meshes, color, opacity, smoothing, down sampling, type of representation, is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Free, Available for download, Freely available nlx_155578 SCR_000043 2026-09-19 12:49:14 2
Altered States Database
 
Resource Report
Resource Website
1+ mentions
Altered States Database (RRID:SCR_016350) ASDB data or information resource, database Database as an open science framework with a scientific data extracted from scientific literature about various altered states of consciousness assessed with questionnaires. Used to compare what experiences are elicited by different drugs and non-pharmacological methods that induce altered states to help to understand human consciousness functions. Is listed by Neuroimaging Informatics Tools. altered, state, database, comprised, questionnaire, data, consciousness, neuroscience is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) VolkswagenStiftung ;
Wikimedia Foundation ;
Stifterverband
DOI:10.17605/OSF.IO/8MBRU Free, Freely available http://alteredstatesdb.org/#focus SCR_016350 Altered States Database 2026-09-19 12:57:35 2
dinifti
 
Resource Report
Resource Website
1+ mentions
dinifti (RRID:SCR_000303) dinifti software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Software which converts DICOM images to NIfTI format. analyze, console (text based), dicom, format conversion, freebsd, linux, magnetic resonance, nifti, posix/unix-like is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
has parent organization: New York University; New York; USA
THIS RESOURCE IS NO LONGER IN SERVICE nlx_155843 http://www.nitrc.org/projects/dinifti, http://cbi.nyu.edu/software/dinifti.php, https://sources.debian.org/src/dicomnifti/ SCR_000303 NYU CBI DICOM to NIfTI Converter 2026-09-19 12:57:41 2
ShapeWorks
 
Resource Report
Resource Website
1+ mentions
ShapeWorks (RRID:SCR_000424) ShapeWorks software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE.Documented on September 2, 2022. Software that is an open-source distribution of a new method for constructing compact statistical point-based models of ensembles of similar shapes that does not rely on any specific surface parameterization. The method requires very little preprocessing or parameter tuning, and is applicable to a wide range of shape analysis problems, including nonmanifold surfaces and objects of arbitrary topology. The proposed correspondence point optimization uses an entropy-based minimization that balances the simplicity of the model (compactness) with the accuracy of the surface representations. The ShapeWorks software includes tools for preprocessing data, computing point-based shape models, and visualizing the results. c++, console (text based), linux, macos, microsoft, magnetic resonance, posix/unix-like, rendering, shape analysis, surface rendering, visualization, win32 (ms windows), windows, workflow is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: University of Utah; Utah; USA
NCRR 5P41RR012553-15;
NIGMS 8 P41 GM103545-15
THIS RESOURCE IS NO LONGER IN SERVICE nlx_155961 http://www.nitrc.org/projects/shapeworks SCR_000424 2026-09-19 12:57:41 1
CIFTI Connectivity File Format
 
Resource Report
Resource Website
1+ mentions
CIFTI Connectivity File Format (RRID:SCR_000852) CIFTI Connectivity File Format software application, software resource, systems interoperability software Standardizes file formats for the storage of connectivity data. These formats are developed by the Human Connectome Project and other interested parties. Use the MEDIAWIKI entry in the menu on the left for more information about the CIFTI file formats. Access the CIFTI discussion forum using the Forums entry in the menu on the left. Subscribe to the discussion forum and you will be informed about issues involving the CIFTI file formats via email. magnetic resonance is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Free, Available for download, Freely available nlx_155527 SCR_000852 Connectivity Informatics Technology Initiative Connectivity File Format 2026-09-19 12:57:42 7
Group Level Imputation of Statistic Maps
 
Resource Report
Resource Website
Group Level Imputation of Statistic Maps (RRID:SCR_002397) Group Level Imputation of Statistic Maps software resource, software toolkit A software toolkit that performs multiple imputation for group level, single sample t-tests. Whole brain group level statistic maps from fMRI rarely cover the entire brain as a result of missing data. Missingness between subjects in fMRI datasets can result from susceptibility artifacts, bounding box (acquisition parameters), and small differences in post-normalized morphology. The toolkit consists of several interactive command line scripts that guide the user to map the spatial distribution of missing data across contrast images, calculate spatial neighborhood averages that help impute values, perform conventional and multiple imputed t-statistics, save the results to brain maps, and create result tables. The toolkit contains an instruction manual (pdf), two Matlab scripts and one R-Statistics script, which depend on functions defined in the popular SPM toolbox and functions defined in the MICE package for (R). magnetic resonance, imputation, t-test, fmri is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC) Free, Available for download, Freely available nlx_155768 SCR_002397 2026-09-19 12:57:45 0
Measure Projection Toolbox
 
Resource Report
Resource Website
1+ mentions
Measure Projection Toolbox (RRID:SCR_002429) MPT software resource, software toolkit This toolbox is an EEGLAB plugin for performing Measure Projection Analysis. Measure Projection Analysis (MPA) is a novel probabilistic multi-subject inference method that overcomes EEG Independent Component (IC) clustering issues by abandoning the notion of distinct IC clusters. Instead, it searches voxel by voxel for brain regions having event-related IC process dynamics that exhibit statistically significant consistency across subjects and/or sessions as quantified by the values of various EEG measures. Local-mean EEG measure values are then assigned to all such locations based on a probabilistic model of IC localization error and inter-subject anatomical and functional differences. reusable library, eeg, meg, electrocorticography, matlab, statistical operation, surrogate data analysis, visualization, measure projection analysis is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: EEGLAB
has parent organization: Swartz Center for Computational Neuroscience
Free, Available for download, Freely available nlx_155809 http://www.nitrc.org/projects/measure_project SCR_002429 Measure Projection Toolbox (MPT) 2026-09-19 12:57:45 3
Computational Morphometry Toolkit
 
Resource Report
Resource Website
10+ mentions
Computational Morphometry Toolkit (RRID:SCR_002234) CMTK software application, software resource, software toolkit A software toolkit for computational morphometry of biomedical images, CMTK comprises a set of command line tools and a back-end general-purpose library for processing and I/O. The command line tools primarily provide the following functionality: registration (affine and nonrigid; single and multi-channel; pairwise and groupwise), image correction (MR bias field estimation; interleaved image artifact correction; EPI unwarping), processing (filters; combination of segmentations via voting and STAPLE; shape-based averaging), statistics (t-tests; general linear model). CMTK is implemented in C++ with parallel processing using POSIX Threads (SMP), OpenMP (SMP), Grand Central Dispatch (SMP), and CUDA (GPU). Supported file formats include Analyze (r/w), NIFTI (r/w), Nrrd (r/w), DICOM (read), BioRad (read). Data exchange with other toolkits, such as ITK, FSL, AFNI, SPM, etc. is thus easily accomplished. reusable library, analyze, anatomic, artifact removal, atlas application, c, c++, console (text based), cygwin, dicom, domain independent, format conversion, image display, image reconstruction, image-to-image, labeling, linear, linux, macos, microsoft, magnetic resonance, nifti-1, nrrd, posix/unix-like, principal component analysis, region of interest, registration, regression, resampling, segmentation, sh/bash, spatial transformation, statistical operation, sunos/solaris, two dimensional display, unix shell, visualization, warping, win32 (ms windows), windows, workflow is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
has parent organization: neurodebian
Free, Available for download, Freely available nlx_155536 http://www.nitrc.org/projects/cmtk, https://sources.debian.org/src/cmtk/ SCR_002234 Computational Morphometry Toolkit (CMTK) 2026-09-19 12:57:44 38
RFT FDR
 
Resource Report
Resource Website
RFT FDR (RRID:SCR_002533) RFT_FDR software application, software resource So far there is a lack for Random Field Theory (RFT) -based multiple comparison correction for surfaces generated in Freesurfer software package. This set of Matlab-based functions can be used for that purpose. They are based on Worsley?s SurfStat toolbox. You also need to have installed Freesurfer software package and included the Freesurfer?s matlab subdirectory in the Matlab?s search path. In addition, this tool implements the RFT-FDR hierarchical correction that can be used for optimizing the amount of smoothing in cortical thickness analyses (Neuroimage 52, 158-171). console (text based), gnome, kde, matlab, mgh/mgz, modeling, magnetic resonance, os independent, rendering, statistical operation, surface analysis, surface rendering, thickness, visualization, random field theory is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: FreeSurfer
Free, Available for download, Freely available nlx_155938 SCR_002533 RFT-FDR, RFT FDR 2026-09-19 12:57:45 0
NIRx2nirs: A NIRx to .nirs data converter
 
Resource Report
Resource Website
1+ mentions
NIRx2nirs: A NIRx to .nirs data converter (RRID:SCR_002492) NIRx2nirs software application, software resource A matlab script which takes near-infrared spectroscopy data recorded by NIRx system(s) and converts it to a .nirs file format for use with the HOMER2 NIRS processing pacakge. hardware, nirs, fnir, optical imaging, optical imaging, physiological recording is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: Homer2
Free, Available for download, Freely available nlx_155887 SCR_002492 2026-09-19 12:57:45 1
MBF BioScience: Stereo Investigator
 
Resource Report
Resource Website
100+ mentions
MBF BioScience: Stereo Investigator (RRID:SCR_002526) instrument resource, software resource Stereo Investigator system includes microscope, computer, and Stereo Investigator software. Software works with Brightfield, Multi-Channel Fluorescence, Confocal, and Structured Illumination Microscopes. System used to provide estimates of number, length, area, and volume of cells or biological structures in tissue specimen in areas of neuroscience including neurodegenerative diseases, neuropathy, memory, and behavior, pulmonary research, spinal cord research, and toxicology. stereology, MBF Bioscience, number, length, area, volume cells, biological structures, tissue specimen is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: SoftCite
Restricted SciRes_000114, SCR_024705, SCR_018948 http://www.nitrc.org/projects/si_stereology SCR_002526 Stereo Investigator system 2026-09-19 12:57:45 162
Slicer3 Example Modules
 
Resource Report
Resource Website
Slicer3 Example Modules (RRID:SCR_002559) Slicer3 Example Modules software application, software development tool, software resource Example Slicer3 plugins that can be built against a Slicer3 build or a Slicer3 installation. Note: these are for 3D Slicer version 3. There is now a version 4 of 3D Slicer available. Information about extensions for version 4 can be found at the following links: http://www.slicer.org/slicerWiki/index.php/Documentation/Nightly/SlicerApplication/ExtensionsManager http://www.slicer.org/slicerWiki/index.php/Documentation/Nightly/Developers/Tutorials/BuildTestPackageDistributeExtensions analyze, c++, console (text based), computed tomography, dicom, linux, macos, microsoft, magnetic resonance, nifti, pet, spect, platform or development environment, posix/unix-like, win32 (ms windows), windows, windows nt/2000, windows vista is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: 3D Slicer
is related to: INCF Software Center
Free, Available for download, Freely available nlx_155965 SCR_002559 2026-09-19 12:57:45 0
SPHARM-MAT
 
Resource Report
Resource Website
1+ mentions
SPHARM-MAT (RRID:SCR_002545) SPHARM-MAT software application, software resource, software toolkit A matlab-based 3D shape modeling and analysis toolkit, and is designed to aid statistical shape analysis for identifying morphometric changes in 3D structures of interest related to different conditions. SPHARM-MAT is implemented based on a powerful 3D Fourier surface representation method called SPHARM, which creates parametric surface models using spherical harmonics. analyze, c, matlab, microsoft, morphology, magnetic resonance, nifti, posix/unix-like, quantification, quantitative shape analysis, shape analysis, shape decomposition, spherical harmonics, surface analysis, win32 (ms windows), windows, parametric surface model, spherical harmonics, 3d, shape modeling, analysis, morphometry is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: Indiana University School of Medicine; Indiana; USA
NIBIB R03EB008674-01 Free, Available for download, Freely available nlx_155952 http://www.nitrc.org/projects/spharm-mat SCR_002545 2026-09-19 12:57:45 2
cortex
 
Resource Report
Resource Website
100+ mentions
cortex (RRID:SCR_002467) cortex software application, software resource Software package with functions that will help researchers plan how many subjects per group need to be included in an MRI-based cortical thickness study to ensure a thickness difference is detected. The package requires cortical thickness mapping and co-registration to be carried out using Freesurfer. The power analyses are implemented in the R software package., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. clinical neuroinformatics, mgh/mgz, magnetic resonance, r, surface analysis, thickness, mri, cortical thickness, morphometry, neuroimaging, power analysis, study design, bio.tools is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: bio.tools
is listed by: Debian
has parent organization: Brain Research Institute
PMID:22807270 THIS RESOURCE IS NO LONGER IN SERVICE nlx_155842, biotools:cortex http://brain.org.au/software/cortex/power, http://www.nitrc.org/projects/cortex, https://bio.tools/cortex SCR_002467 Sample Size Estimates for Well-Powered Cross-Sectional Cortical Thickness Studies 2026-09-19 12:57:45 374
Diffusion Tractography with Kalman Filter
 
Resource Report
Resource Website
Diffusion Tractography with Kalman Filter (RRID:SCR_002585) Diffusion Tractography with Kalman Filter software application, software resource Software framework which uses an unscented Kalman filter for performing tractography. At each point on the fiber the most consistent direction is found as a mixture of previous estimates and of the local model. It is very easy to expand the framework and to implement new fiber representations for it. Currently it is possible to tract fibers using two different 1-, 2-, or 3-tensor methods. Both methods use a mixture of Gaussian tensors. One limits the diffusion ellipsoids to a cylindrical shape (the second and third eigenvalue are assumed to be identical) and the other one uses a full tensor representation. The project is written in C++. It could be used both as a Slicer3 module and as a standalone commandline application. c++, diffusion mr fiber tracking, fiber tracking, microsoft, magnetic resonance, nrrd, posix/unix-like, tractography, win32 (ms windows), windows is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: 3D Slicer
has parent organization: Harvard Medical School; Massachusetts; USA
PMID:19694258 Free, Available for download, Freely available nlx_155990 SCR_002585 Tractography with Unscented Kalman Filter 2026-09-19 12:57:45 0

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