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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
T1DBase
 
Resource Report
Resource Website
100+ mentions
T1DBase (RRID:SCR_007959) data or information resource, data repository, database, resource, service resource, storage service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 26,2019. In October 2016, T1DBase has merged with its sister site ImmunoBase (https://immunobase.org). Documented on March 2020, ImmunoBase ownership has been transferred to Open Targets (https://www.opentargets.org). Results for all studies can be explored using Open Targets Genetics (https://genetics.opentargets.org). Database focused on genetics and genomics of type 1 diabetes susceptibility providing a curated and integrated set of datasets and tools, across multiple species, to support and promote research in this area. The current data scope includes annotated genomic sequences for suspected T1D susceptibility regions; genetic data; microarray data; and global datasets, generally from the literature, that are useful for genetics and systems biology studies. The site also includes software tools for analyzing the data. genetics, beta cell, gene, variant, region, genomics, gene expression, genome-wide association study, data analysis service, bio.tools is used by: NIF Data Federation
is used by: NIDDK Information Network (dkNET)
is listed by: NIDDK Information Network (dkNET)
is listed by: Debian
is listed by: bio.tools
is related to: dkCOIN
has parent organization: University of Cambridge; Cambridge; United Kingdom
Type 1 diabetes. Diabetes Wellcome Trust ;
NIDDK ;
Juvenile Diabetes Research Foundation
PMID:20937630 THIS RESOURCE IS NO LONGER IN SERVICE. nif-0000-03531, biotools:t1dbase https://bio.tools/t1dbase SCR_007959 SciCrunch Registry T1DBase - Type 1 Diabetes Database 2026-11-07 11:56:27 147
HilbertVis
 
Resource Report
Resource Website
1+ mentions
HilbertVis (RRID:SCR_007862) HilbertVis software resource Software tool that allows to display very long data vectors in a space-efficient manner, allowing the user to visually judge the large scale structure and distribution of features simultaneously with the rough shape and intensity of individual features. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: European Bioinformatics Institute
DOI:10.1093/bioinformatics/btp152 OMICS_00627, biotools:hilbertvis https://bio.tools/hilbertvis, https://sources.debian.org/src/r-bioc-hilbertvis/ SCR_007862 SciCrunch Registry 2026-11-07 11:56:21 4
BRIG
 
Resource Report
Resource Website
500+ mentions
BRIG (RRID:SCR_007802) BRIG software resource A cross-platform (Windows/Mac/Unix) application that can display circular comparisons between a large number of genomes, with a focus on handling genome assembly data. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
DOI:10.1186/1471-2164-12-402 OMICS_00929, biotools:brig https://bio.tools/brig, https://sources.debian.org/src/brig/ SCR_007802 SciCrunch Registry BLAST Ring Image Generator 2026-11-07 11:56:26 561
dbEST
 
Resource Report
Resource Website
100+ mentions
dbEST (RRID:SCR_008132) data or information resource, data repository, database, service resource, storage service resource Database as a division of GenBank that contains sequence data and other information on single-pass cDNA sequences, or Expressed Sequence Tags, from a number of organisms. data, sequence, single, pass, cDNA, express, tag, bio.tools, gold standard is listed by: Debian
is listed by: bio.tools
has parent organization: NCBI
PMID:8401577 biotools:dbest, nif-0000-20937, r3d100010648 http://www.ncbi.nlm.nih.gov/dbEST/, https://bio.tools/dbest, https://doi.org/10.17616/R3FG8P SCR_008132 SciCrunch Registry database Expressed Sequence Tag (EST), database Expressed Sequence Tag 2026-11-07 11:56:26 186
lobSTR
 
Resource Report
Resource Website
10+ mentions
lobSTR (RRID:SCR_008030) lobSTR software resource A software tool for profiling Short Tandem Repeats (STRs) from high throughput sequencing data., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Massachusetts Institute of Technology; Massachusetts; USA;
PMID:22522390 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00109, biotools:lobstr https://bio.tools/lobstr SCR_008030 SciCrunch Registry lobSTR - Profiling STRs in personal genomes 2026-11-07 11:56:23 47
ActiveDriver
 
Resource Report
Resource Website
10+ mentions
ActiveDriver (RRID:SCR_008104) ActiveDriver data analysis software, data processing software, sequence analysis software, software application, software resource A statistical method for interpreting variations in protein sequence (e.g. coding SNPs in the population, SNVs in cancer genomes) in the context of protein post-translational signaling modifications. Protein sequence variation, variation interpretation, protein sequence, protein post-translational signaling modifications, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:ActiveDriver, OMICS_00140 http://reimandlab.org/software/activedriver/, https://cran.r-project.org/web/packages/ActiveDriver/ActiveDriver.pdf, https://bio.tools/ActiveDriver SCR_008104 SciCrunch Registry 2026-11-07 11:56:26 27
QIIME
 
Resource Report
Resource Website
10000+ mentions
QIIME (RRID:SCR_008249) data analysis software, data processing software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 23,2023.Software package for comparison and analysis of microbial communities, primarily based on high-throughput amplicon sequencing data, but also supporting analysis of other types of data. QIMME analyzes and transforms raw sequencing data generated on Illumina or other platforms to publication quality graphics and statistics. microbiome, microbial community, sequence data, data analysis software, bio.tools is used by: SortMeRNA
is used by: Nephele
is listed by: OMICtools
is listed by: Human Microbiome Project
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
has parent organization: University of Colorado Boulder; Colorado; USA
DOI:10.1038/nmeth.f.303 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01118, SCR_011948, OMICS_01521, biotools:qiime https://bio.tools/qiime SCR_008249 SciCrunch Registry Quantitative Insights Into Microbial Ecology 2026-11-07 11:56:30 11177
IsaCGH
 
Resource Report
Resource Website
IsaCGH (RRID:SCR_008375) IsaCGH software resource Software to analyze CNV that will now normalize arrays CGH and it will visually integrate different genome annotations. microarray, array cgh, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
OMICS_00727, biotools:isacgh https://bio.tools/isacgh SCR_008375 SciCrunch Registry 2026-11-07 11:56:31 0
G protein receptor interaction feature finding instrument
 
Resource Report
Resource Website
10+ mentions
G protein receptor interaction feature finding instrument (RRID:SCR_008343) analysis service resource, production service resource, resource, service resource Griffin (G-protein-receptor interacting feature finding instrument) is a high-throughput system to predict GPCR - G-protein coupling selectively with the input of GPCR sequence and ligand molecular weight. This system consists of two parts: 1) HMM section using family specific multiple alignment of GPCRs, 2) SVM section using physico-chemical feature vectors in GPCR sequence. G-protein coupled receptors (GPCR), which is composed of seven transmembrane helices, play a role as interface of signal transduction. The external stimulation for GPCR, induce the coupling with G-protein (Gi/o, Gq/11, Gs, G12/13) followed by different kinds of signal transduction to inner cell. About half of distributed drugs are intending to control this GPCR - G-protein binding system, and therefore this system is important research target for the development of effective drug. For this purpose, it is necessary to monitor, effectively and comprehensively, of the activation of G-protein by identifying ligand combined with GPCR. Since, at present, it is difficult to construct such biochemical experiment system, if the answers for experimental results can be prepared beforehand by using bioinformatics techniques, large progress is brought to G-protein related drug design. Previous works for predicting GPCR-G protein coupling selectivity are using sequence pattern search, statistical models, and HMM representations showed high sensitivity of predictions. However, there are still no works that can predict with both high sensitivity and specificity. In this work we extracted comprehensively the physico-chemical parameters of each part of ligand, GPCR and G-protein, and choose the parameters which have strong correlation with the coupling selectivity of G-protein. These parameters were put as a feature vector, used for GPCR classification based on SVM. drug, alignment, biochemical, bioinformatic, coupling, gpcr, g-protein, helix, instrument, interface, ligand, molecular, pattern, physico-chemical, receptor interacting, sequence, signal transduction, stimulation, svm, system, technique, transmembrane, weight, instrument, equipment, hardware, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Computational Biology Research Center Core Facility
National Institute of Advanced Industrial Science and Technology nif-0000-25210, biotools:griffin https://bio.tools/griffin SCR_008343 SciCrunch Registry Griffin 2026-11-07 11:56:26 21
FigTree
 
Resource Report
Resource Website
10000+ mentions
FigTree (RRID:SCR_008515) data processing software, data visualization software, software application, software resource A graphical viewer of phylogenetic trees and a program for producing publication-ready figures. It is designed to display summarized and annotated trees produced by BEAST. data visualization software, graphical viewer, phylogenetic tree, annotate is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
has parent organization: University of Edinburgh; Scotland; United Kingdom
OMICS_04268, nif-0000-30567 https://sources.debian.org/src/figtree/ SCR_008515 SciCrunch Registry FigTree 2026-11-07 11:56:35 12345
BioSig: An Imaging Bioinformatics System for Phenotypic Analysis
 
Resource Report
Resource Website
100+ mentions
BioSig: An Imaging Bioinformatics System for Phenotypic Analysis (RRID:SCR_008428) BioSig data processing software, image processing software, software application, software library, software resource, software toolkit Software library for processing of electroencephalogram (EEG) and other biomedical signals like electroencephalogram (EEG), electrocorticogram (ECoG), electrocardiogram (ECG), electrooculogram (EOG), electromyogram (EMG), respiration, and so on. Biosig contains tools for quality control, artifact processing, time series analysis, feature extraction, classification and machine learning, and tools for statistical analysis. Many tools are able to handle data with missing values (statistics, time series analysis, machine learning). Another feature is that more then 40 different data formats are supported, and a number of converters for EEG,, ECG and polysomnography are provided. Biosig has been widely used for scientific research on EEG-based BraiN-Computer Interfaces (BCI), sleep research, and ECG and HRV analysis. It provides software interfaces several programming languages (C, C++, Matlab/Octave, Python), and it provides also an interactive viewing and scoring software for adding, and editing of annotations, markers and events. application, autocorrelation, bsd, c, c++, connectivity analysis, correlation, cross-correlation, directed transfer analysis, discriminant analysis, domain independent, eeg, meg, electrocorticography, end event related potential, format conversion, german, gnome, granger causality, information theory, kde, linux, matlab, microsoft, multivariate analysis, partial directed coherence, posix/unix-like, python, regression, spectral analysis, statistical operation, temporal transformation, time domain analysis, win32 (ms windows), windows, electrocorticogram, electrocardiogram, electrooculogram, electromyogram, respiration, signal, processing, biosignal is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
has parent organization: Lawrence Berkeley National Laboratory
DOI:10.1109/MC.2008.407 Free, Available for download, Freely available nif-0000-30190 http://www.nitrc.org/projects/biosig, https://sources.debian.org/src/biosig-tools/ SCR_008428 SciCrunch Registry 2026-11-07 11:56:33 165
CAT
 
Resource Report
Resource Website
10+ mentions
CAT (RRID:SCR_008421) CAT software resource A repository of tools for analysis and annotation of CAZYmes (Carbohydrate Active enZYmes)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01676, biotools:CAt https://bio.tools/CAT SCR_008421 SciCrunch Registry 2026-11-07 11:56:27 13
Augustus
 
Resource Report
Resource Website
1000+ mentions
Augustus (RRID:SCR_008417) data analysis software, data processing software, sequence analysis software, software application, software resource, web application Software for gene prediction in eukaryotic genomic sequences. Serves as a basis for further steps in the analysis of sequenced and assembled eukaryotic genomes. software, gene, prediction, eucaryotic, genomic, sequence is used by: BRAKER
is used by: BRO_annotation
is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
works with: Gsnap2Augustus
Deutsche Forschungsgemeinschaft (DFG) HO4545/1-1;;
STA1009/6-1 ;
Institute for Mathematics and Computer Science ;
Ernst Moritz Arndt University of Greifswald
PMID:23700307
DOI:10.1093/bioinformatics/btw494
Free, Available for download, Freely available SCR_015981, OMICS_07777, nif-0000-30133 https://sources.debian.org/src/autodock-vina/ SCR_008417 SciCrunch Registry Augustus: Gene Prediction, WebAUGUSTUS, Augustus, Augustus [gene prediction] 2026-11-07 11:56:27 3886
TopFIND
 
Resource Report
Resource Website
10+ mentions
TopFIND (RRID:SCR_008918) TopFIND data or information resource, data repository, database, service resource, storage service resource An integrated knowledgebase focused on protein termini, their formation by proteases and functional implications. It contains information about the processing and the processing state of proteins and functional implications thereof derived from research literature, contributions by the scientific community and biological databases. It lists more than 120,000 N- and C-termini and almost 10,000 cleavages. TopFIND is a resource for comprehensive coverage of protein N- and C-termini discovered by all available in silico, in vitro as well as in vivo methodologies. It makes use of existing knowledge by seamless integration of data from UniProt and MEROPS and provides access to new data from community submission and manual literature curating. It renders modifications of protein termini, such as acetylation and citrulination, easily accessible and searchable and provides the means to identify and analyse extend and distribution of terminal modifications across a protein. The data is presented to the user with a strong emphasis on the relation to curated background information and underlying evidence that led to the observation of a terminus, its modification or proteolytic cleavage. In brief the protein information, its domain structure, protein termini, terminus modifications and proteolytic processing of and by other proteins is listed. All information is accompanied by metadata like its original source, method of identification, confidence measurement or related publication. A positional cross correlation evaluation matches termini and cleavage sites with protein features (such as amino acid variants) and domains to highlight potential effects and dependencies in a unique way. Also, a network view of all proteins showing their functional dependency as protease, substrate or protease inhibitor tied in with protein interactions is provided for the easy evaluation of network wide effects. A powerful yet user friendly filtering mechanism allows the presented data to be filtered based on parameters like methodology used, in vivo relevance, confidence or data source (e.g. limited to a single laboratory or publication). This provides means to assess physiological relevant data and to deduce functional information and hypotheses relevant to the bench scientist. TopFIND PROVIDES: * Integration of protein termini with proteolytic processing and protein features * Displays proteases and substrates within their protease web including detailed evidence information * Fully supports the Human Proteome Project through search by chromosome location CONTRIBUTE * Submit your N- or C-termini datasets * Contribute information on protein cleavages * Provide detailed experimental description, sample information and raw data protein, n-termini, c-termini, protease, protein cleavage, proteomics, cleavage site, terminus, modification, proteolytic processing, protein function, domain structure, protein termini, terminus modification, protease, substrate, protease inhibitor, protein interaction, protein-protein interaction, interaction, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: UniProtKB
is related to: PSICQUIC Registry
is related to: MEROPS
has parent organization: University of British Columbia; British Columbia; Canada
Canadian Institutes of Health Research ;
Cancer Research Society ;
British Columbia Proteomics Network ;
Metalloproteinase Proteomics and Systems Biology ;
Michael Smith Foundation for Health Research ;
Breast Cancer Society of Canada ;
Alexander von Humboldt-Stiftung ;
BMBF ;
German Academic Exchange Service
PMID:22102574
PMID:21822272
Public, Acknowledgement requested biotools:topfind, r3d100012721, nlx_151607 https://bio.tools/topfind, https://doi.org/10.17616/R3KB8J, https://doi.org/10.17616/R3KB8J SCR_008918 SciCrunch Registry Termini oriented protein Function Inferred Database 2026-11-07 11:56:40 29
FGDP
 
Resource Report
Resource Website
FGDP (RRID:SCR_008910) FGDP software resource A Java-based, Microarray or Genechip data analysis system. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Fox Chase Cancer Center
PMID:14734324 GNU General Public License OMICS_00756, biotools:fgdp https://bio.tools/fgdp SCR_008910 SciCrunch Registry Functional Genomics Data Pipeline (FGDP), Functional Genomics Data Pipeline 2026-11-07 11:56:39 0
Generic GO Term Finder
 
Resource Report
Resource Website
100+ mentions
Generic GO Term Finder (RRID:SCR_008870) GOTermFinder, GO-TermFinder, GO Term Finder, GO::TermFinder analysis service resource, data analysis service, data processing software, production service resource, service resource, software application, software resource, source code The Generic GO Term Finder finds the significant GO terms shared among a list of genes from an organism, displaying the results in a table and as a graph (showing the terms and their ancestry). The user may optionally provide background information or a custom gene association file or filter evidence codes. This tool is capable of batch processing multiple queries at once. GO::TermFinder comprises a set of object-oriented Perl modules GO::TermFinder can be used on any system on which Perl can be run, either as a command line application, in single or batch mode, or as a web-based CGI script. This implementation, developed at the Lewis-Sigler Institute at Princeton, depends on the GO-TermFinder software written by Gavin Sherlock and Shuai Weng at Stanford University and the GO:View module written by Shuai Weng. It is made publicly available through the GMOD project. The full source code and documentation for GO:TermFinder are freely available from http://search.cpan.org/dist/GO-TermFinder/. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene ontology, gene, graph, visualization, genomics, gene association, ontology or annotation visualization, term enrichment, ontology, process, function, component, enrichment, bio.tools is listed by: 3DVC
is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Generic Model Organism Database Project
has parent organization: Princeton University; New Jersey; USA
has parent organization: Comprehensive Perl Archive Network
NHGRI 1R01HG002732 PMID:15297299 Free for academic use nlx_149293, biotools_go_term_finder https://bio.tools/go_term_finder SCR_008870 SciCrunch Registry Generic Gene Ontology (GO) Term Finder, Generic Gene Ontology Term Finder 2026-11-07 11:56:43 108
LegumeIP
 
Resource Report
Resource Website
10+ mentions
LegumeIP (RRID:SCR_008906) LegumeIP analysis service resource, data analysis service, data or information resource, database, production service resource, service resource LegumeIP is an integrative database and bioinformatics platform for comparative genomics and transcriptomics to facilitate the study of gene function and genome evolution in legumes, and ultimately to generate molecular based breeding tools to improve quality of crop legumes. LegumeIP currently hosts large-scale genomics and transcriptomics data, including: * Genomic sequences of three model legumes, i.e. Medicago truncatula, Glycine max (soybean) and Lotus japonicus, including two reference plant species, Arabidopsis thaliana and Poplar trichocarpa, with the annotation based on UniProt TrEMBL, InterProScan, Gene Ontology and KEGG databases. LegumeIP covers a total 222,217 protein-coding gene sequences. * Large-scale gene expression data compiled from 104 array hybridizations from L. japonicas, 156 array hybridizations from M. truncatula gene atlas database, and 14 RNA-Seq-based gene expression profiles from G. max on different tissues including four common tissues: Nodule, Flower, Root and Leaf. * Systematic synteny analysis among M. truncatula, G. max, L. japonicus and A. thaliana. * Reconstruction of gene family and gene family-wide phylogenetic analysis across the five hosted species. LegumeIP features comprehensive search and visualization tools to enable the flexible query on gene annotation, gene family, synteny, relative abundance of gene expression. gene function, genome evolution, legume, gene, genome, plant, genomics, transcriptomic, gene annotation, gene family, synteny, gene expression, blast, genomic sequence, microarray, rna-seq, comparative genomics, bio.tools is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is related to: UniProt
is related to: InterProScan
is related to: Gene Ontology
is related to: KEGG
has parent organization: Samuel Roberts Noble Foundation
Samuel Roberts Noble Foundation ;
NSF ABI-0960897
PMID:22110036 biotools:legumeip, nlx_151455 https://bio.tools/legumeip SCR_008906 SciCrunch Registry LegumeIP: an integrative database for comparative genomics and transcriptomics of model legumes, LegumeIP - An Integrative Platform to Study Gene Function and Genome Evolution in Legumes 2026-11-07 11:56:45 23
KGGSeq
 
Resource Report
Resource Website
50+ mentions
KGGSeq (RRID:SCR_005311) KGGSeq software resource A biological Knowledge-based mining platform for Genomic and Genetic studies using Sequence data. The software platform, constituted of bioinformatics and statistical genetics functions, makes use of valuable biologic resources and knowledge for sequencing-based genetic mapping of variants / genes responsible for human diseases / traits. It facilitates geneticists to fish for the genetic determinants of human diseases / traits in the big sea of DNA sequences. KGGSeq has paid attention to downstream analysis of genetic mapping. The framework was implemented to filter and prioritize genetic variants from whole exome sequencing data. genomic, genetic, sequence, mutation, exome sequencing, disease, gene, variant, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
Monogenic disorder, Cancer PMID:22241780 biotools:kggseq, OMICS_02260 https://bio.tools/kggseq SCR_005311 SciCrunch Registry KGGSeq: A biological Knowledge-based mining platform for Genomic and Genetic studies using Sequence data 2026-11-07 11:55:55 58
Scripture
 
Resource Report
Resource Website
10+ mentions
Scripture (RRID:SCR_005269) Scripture software resource Software for transcriptome reconstruction that relies solely on RNA-Seq reads and an assembled genome to build a transcriptome ab initio. The statistical methods to estimate read coverage significance are also applicable to other sequencing data. Scripture also has modules for ChIP-Seq peak calling. transcriptome, rna-seq read, genome sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Alt Event Finder
has parent organization: Broad Institute
PMID:20436462 biotools:scripture, OMICS_01265 https://bio.tools/scripture SCR_005269 SciCrunch Registry 2026-11-07 11:55:55 11
Hmmer
 
Resource Report
Resource Website
5000+ mentions
Hmmer (RRID:SCR_005305) HMMER analysis service resource, data analysis service, data analysis software, data processing software, production service resource, service resource, software application, software resource Tool for searching sequence databases for homologs of protein sequences, and for making protein sequence alignments. It implements methods using probabilistic models called profile hidden Markov models (profile HMMs). Compared to BLAST, FASTA, and other sequence alignment and database search tools based on older scoring methodology, HMMER aims to be significantly more accurate and more able to detect remote homologs because of the strength of its underlying mathematical models. In the past, this strength came at significant computational expense, but in the new HMMER3 project, HMMER is now essentially as fast as BLAST. homolog, protein sequence, source code, FASEB list is used by: Mantis
is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: SoftCite
is related to: VectorBase
has parent organization: Janelia Research
Howard Hughes Medical Institute PMID:21593126
DOI:10.1093/bioinformatics/14.9.755
OMICS_00996, nlx_144358 https://sources.debian.org/src/hmmer/ SCR_005305 SciCrunch Registry HMMER - biosequence analysis using profile hidden Markov models 2026-11-07 11:55:30 9520

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